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Options forfeited (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Weighted-average discount rate Operating Lease, Weighted Average Discount Rate, Percent Risk-free interest rate, Minimum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Schedule of Stock Unit Award Activity PSU Nonvested Restricted Stock Shares Activity [Table Text Block] Segment Reporting [Table] Segment Reporting [Table] Number of shares available for grant (in shares) Beginning balance (in shares) Ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Sale of Stock Sale of Stock [Axis] Weighted- Average Remaining Contractual Term (Years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Cash Cash [Member] Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Other income, net: Other Nonoperating Income (Expense) [Abstract] All Trading Arrangements All Trading Arrangements [Member] Investments in fair market value, continuous unrealized loss position, less than 12 months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months Other Performance Measure, Amount Other Performance Measure, Amount Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Loss from operations Operating Income (Loss) Current Fiscal Year End Date Current Fiscal Year End Date Remainder of 2026 Other Commitment, to be Paid, Remainder of Fiscal Year Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Unrealized foreign exchange loss (gain) Unrealized Gain (Loss), Foreign Currency Transaction, after Tax Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Common stock, dividends, declared (in dollars per share) Common Stock, Dividends, Per Share, Declared Entity File Number Entity File Number Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Schedule of Contractual Maturities of Investments Investments Classified by Contractual Maturity Date [Table Text Block] Schedule of Activity Under Stock Option Plans Share-Based Payment Arrangement, Option, Activity [Table Text Block] Weighted- Average Exercise Price Per Share Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Common stock, shares issued (in shares) Common Stock, Shares, Issued Measure: Measure [Axis] Assignment Agreement Assignment Agreement [Member] Assignment Agreement. 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Entity Small Business Entity Small Business Comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent 2029 Lessee, Operating Lease, Liability, to be Paid, Year Three Termination Date Trading Arrangement Termination Date Shares withheld for taxes (in shares) Share-Based Payment Arrangement, Shares Withheld for Tax Withholding Obligation Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Other assets Other Assets, Noncurrent Document Type Document Type Accrued expenses Accrued Liabilities, Current Fair Value as of Grant Date Award Grant Date Fair Value Beginning balance Ending balance Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Outstanding Aggregate Intrinsic Value, Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Supply Commitment Arrangement [Domain] Supply Commitment Arrangement [Domain] Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Arrangement Duration Trading Arrangement Duration Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Local Phone Number Local Phone Number Reportable Segment Reportable Segment [Member] Reportable Segment Entity Address, Postal Zip Code Entity Address, Postal Zip Code Entity Registrant Name Entity Registrant Name Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract] Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] SWITZERLAND SWITZERLAND Aggregate Intrinsic Value, Vested and expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Commitments and contingencies (Note 6) Commitments and Contingencies Antidilutive Securities, Name Antidilutive Securities, Name [Domain] Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Number of conditional options Number of Conditional Options Number of Conditional Options Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Executive Category: Executive Category [Axis] Supply Commitment [Table] Supply Commitment [Table] Changes in operating assets and liabilities: Increase (Decrease) in Operating Liabilities [Abstract] ATM sales agreement at weighted average price (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Intrinsic Value, Amount Per Share Counterparty Name Counterparty Name [Axis] Liabilities and Stockholders' Equity Liabilities and Equity [Abstract] Other Commitments [Table] Other Commitments [Table] Weighted-Average Remaining Contractual Term (Years), Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted-Average Remaining Contractual Term Additional renewal period Number of Additional Renewal Periods Number of additional renewal periods. All Award Types Award Type [Domain] Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount Remainder of 2026 Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year Fair Value Measurements and Fair Value of Financial Instruments Fair Value Disclosures [Text Block] Level 3 Fair Value, Inputs, Level 3 [Member] U.S. government agency securities US Government Agencies Debt Securities [Member] Funding Arrangements Funding Arrangement [Text Block] Funding arrangement. Expected term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Operating lease, agreement term (in years) Lessee, Operating Lease, Term of Contract Exercise of stock options (in shares) Number Of Options Exercised Excludes Options Exercised From NPLN Number of options exercised, excludes options exercised from NPLN. PEO Name PEO Name Geographical [Axis] Geographical [Axis] Accrued expenses Increase (Decrease) in Accrued Liabilities Restricted cash Restricted Cash Long-Lived Asset, Class Long-Lived Asset, Class [Axis] Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Entity Tax Identification Number Entity Tax Identification Number Potential funding period of award to develop vaccine to prevent infections (in years) Potential Funding Period Of Award To Develop Vaccine To Prevent Infections Potential funding period of award to develop vaccine to prevent infections. Other Commitments [Line Items] Other Commitments [Line Items] Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] options exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Cash, cash equivalents and restricted cash, beginning of period Cash, cash equivalents and restricted cash, end of period Cash, cash equivalents and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Accounts payable Increase (Decrease) in Accounts Payable Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Non-NEOs Non-NEOs [Member] Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Company Organization and Nature of Business Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Measurement Frequency Measurement Frequency [Domain] Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense Employee Stock Employee Stock [Member] Leases Lessee, Operating Leases [Text Block] Net loss per share, basic (in dollars per share) Earnings Per Share, Basic Available for issuance of shares increased (in shares) Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Increase In Available For Grant Share based compensation arrangement by share based payment award number of shares increase in available for grant. Total current assets Assets, Current Statistical Measurement Statistical Measurement [Axis] Insider Trading Arrangements [Line Items] Award Type Award Type [Axis] Lonza Commercial Manufacturing and Supply Agreement Lonza Commercial Manufacturing and Supply Agreement [Member] Lonza commercial manufacturing and supply agreement. Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Accumulated deficit Retained Earnings (Accumulated Deficit) Gross Unrealized Losses Cash And Cash Equivalents Gross Unrealized Loss Before Tax Cash and cash equivalents gross unrealized loss before tax. Restricted cash Restricted Cash, Noncurrent Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Common Stock Common Stock [Member] Fair Value Total Debt Securities, Available-for-Sale Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Cover [Abstract] Cover [Abstract] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Table] Fair Value Measurement Inputs and Valuation Techniques [Table] Equity Awards Adjustments Equity Awards Adjustments [Member] Total liabilities and stockholders' equity Liabilities and Equity Employee Stock Option Stock options Share-Based Payment Arrangement, Option [Member] Segments [Axis] Segments [Axis] Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Asset Class Asset Class [Axis] Plan Name Plan Name [Axis] Agreement termination penalty Agreement Termination Penalty Agreement termination penalty. Tabular List, Table Tabular List [Table Text Block] Schedule of Stock-based Compensation Expense Share-Based Payment Arrangement, Cost by Plan [Table Text Block] Other (expense) income Other Nonoperating Income (Expense) Name Awards Close in Time to MNPI Disclosures, Individual Name Automatic renewal period Automatic Renewal Period Automatic renewal period. Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Performance Contingent Stock Options (PCSOs) Performance Contingent Stock Options (PCSOs) [Member] Performance Contingent Stock Options (PCSOs) Cancelled (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period General and administrative General and administrative General and Administrative Expense Long-Lived Asset, Class Long-Lived Asset, Class [Domain] Average price (in dollars per share) Sale of Stock, Price Per Share Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Preferred stock, $0.001 par value — 10,000,000 shares authorized at June 30, 2026 and December 31, 2025; no shares issued and outstanding at June 30, 2026 and December 31, 2025 Preferred Stock, Value, Issued Employee stock purchase plan Employee Stock Purchase Plan [Member] Employee stock purchase plan. 2020 Employee Stock Purchase Plan Two Thousand Twenty Employee Stock Purchase Plan [Member] Two thousand twenty employee stock purchase plan. Adjustment to Compensation: Adjustment to Compensation [Axis] Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Total non-cancelable purchase commitments due to our key manufacturing partners Other Commitment Potential funding amount of award to develop vaccine to prevent infections Potential Funding Amount Of Award To Develop Vaccine To Prevent Infections Potential funding amount of award to develop vaccine to prevent infections. Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Vested and expected options (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Name Measure Name Income Taxes Income Tax Disclosure [Text Block] Accounts payable Accounts Payable, Current Pay vs Performance Disclosure [Line Items] Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Domain] Commercial Manufacturing and Supply Agreements Commitments Disclosure [Text Block] Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Additional Paid-in Capital Additional Paid-in Capital [Member] Entity Filer Category Entity Filer Category Investments in fair market value, unrealized loss position Debt Securities, Available-for-Sale, Unrealized Loss Position Short-term investments Short-Term Investments Name Trading Arrangement, Individual Name Cash and cash equivalents Cash and cash equivalents Cash and Cash Equivalent Aggregate gross proceeds from issuance of common stock Gross Proceeds From Issuance Of Common Stock Gross proceeds from issuance of common stock. Upfront consideration in cash after agreement date Upfront Consideration in Cash After Agreement Date Upfront consideration in cash after agreement date. Operating lease rent expense recognized Operating Lease, Expense Company Selected Measure Amount Company Selected Measure Amount Depreciation and amortization Depreciation, Depletion and Amortization 2027 Other Commitment, to be Paid, Year One 2020 Plan 2020 Plan [Member] 2020 Plan Weighted-Average Remaining Contractual Term (Years), Vested and expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Entity Address, Address Line Two Entity Address, Address Line Two Schedule Of Stock By Class [Table] Stock, Class of Stock [Table] Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest At The Market Sales Agreement 2026 At The Market Sales Agreement 2026 [Member] At The Market Sales Agreement 2026 Gross Unrealized Gains Cash And Cash Equivalents Gross Unrealized Gain Before Tax Cash and cash equivalents gross unrealized gain before tax. Commercial paper Commercial Paper, Not Included with Cash and Cash Equivalents [Member] Current assets: Assets, Current [Abstract] Weighted-average remaining lease term (in years) Operating Lease, Weighted Average Remaining Lease Term Non-PEO NEO Non-PEO NEO [Member] Entity Address, Address Line One Entity Address, Address Line One Vested and released (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Tax provision Income Tax Expense (Benefit) Award Timing Method Award Timing Method [Text Block] Net increase (decrease) in cash, cash equivalents and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Expected volatility, Minimum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum Net loss Net loss Net loss Net loss Net Income (Loss) Attributable to Parent Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Statement [Table] Statement [Table] Restatement Determination Date: Restatement Determination Date [Axis] Repurposing fee Repurposing Fee Repurposing fee Leerink Partners LLC Leerink Partners LLC [Member] Leerink Partners LLC Certificates of Deposit Certificates of Deposit [Member] Interest income Investment Income, Interest Weighted-Average Exercise Price Per Share, Exercisable (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Thereafter Other Commitment, To Be Paid, After Year Three Other Commitment, To Be Paid, After Year Three Basis of Presentation and Summary of Significant Accounting Policies Basis of Presentation and Significant Accounting Policies [Text Block] Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block]