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Amount of cost to be recognized for option under share-based payment arrangement.

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Exercise or strike price stated in the contract for options indexed to the issuer's equity shares.

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The number of grants made during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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Number of additional shares authorized for issuance under share-based payment arrangement.

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Number of shares authorized for issuance under share-based payment arrangement.

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The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable.

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Amount of accumulated difference between fair value of underlying shares on dates of exercise and exercise price on options exercised (or share units converted) into shares.

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The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology.

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Maximum number of shares that may be issued in accordance with the plan as a proportion of outstanding capital stock.

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Equity-Based Compensation - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026	Jun. 30, 2025	Mar. 31, 2026	Mar. 31, 2025	Aug. 20, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Recognized stock-based compensation expense	$ 18,938	$ 15,415	$ 34,945	$ 29,649
Equity-based compensation expense	18,938	15,415	34,945	29,649
Employee Stock Option
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Intrinsic value of stock options exercised	$ 37,200	$ 5,300	$ 70,500	$ 7,400
Weighted-average fair value of options granted	$ 59.06	$ 25.46	$ 62.3	$ 21.8
Recognized stock-based compensation expense	$ 13,531	$ 12,391	$ 25,536	$ 23,961
Unrecognized stock-based compensation expense	110,300		$ 110,300
Unrecognized compensation cost, recognition period			3 years 2 months 12 days
Equity-based compensation expense	13,531	12,391	$ 25,536	23,961
Employee Stock Option \| Research and Development Arrangement [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Recognized stock-based compensation expense	6,512	5,983	12,229	11,696
Equity-based compensation expense	6,512	5,983	12,229	11,696
Employee Stock Option \| General and Administrative [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Recognized stock-based compensation expense	7,019	6,408	13,307	12,265
Equity-based compensation expense	7,019	6,408	13,307	12,265
Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Recognized stock-based compensation expense	5,200	$ 2,800	9,000	$ 5,200
Unrecognized stock-based compensation expense	$ 56,200		$ 56,200
Unrecognized compensation cost, recognition period			3 years 10 months 24 days
Granted	78,725	191,300	422,967	519,100
Equity-based compensation expense	$ 5,200	$ 2,800	$ 9,000	$ 5,200
Restricted Stock \| Research and Development Arrangement [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Recognized stock-based compensation expense	3,700	1,900	6,400	3,500
Equity-based compensation expense	3,700	1,900	6,400	3,500
Restricted Stock \| General and Administrative [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Recognized stock-based compensation expense	1,500	900	2,600	1,700
Equity-based compensation expense	$ 1,500	900	$ 2,600	1,700
2020 Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares authorized for issuance under plan							4,457,370
Maximum number of shares to be issued, percentage			4.00%
Shares remaining available for future grants	6,464,760		6,464,760
Weighted-average fair value of options granted			$ 97.53
Recognized stock-based compensation expense	$ 200	$ 0	$ 300	$ 0
Performance stock options vesting	60.00%		60.00%			40.00%
Second clinical milestone vesting percentage						40.00%
Third clinical milestone vesting percentage	15.00%		15.00%			20.00%
Granted	0	0	95,000	88,000
Option Indexed to Issuer's Equity, Strike Price		$ 30.17
Performance stock options outstanding	88,000		88,000
Equity-based compensation expense	$ 200	$ 0	$ 300	$ 0
2020 Plan \| Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Granted	0	0	73,672	285,723
2020 Plan \| Performance Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Weighted-average fair value of options granted			$ 126.09
Recognized stock-based compensation expense	$ 200		$ 300
Performance stock options vesting					60.00%	40.00%
Second clinical milestone vesting percentage						40.00%
Third clinical milestone vesting percentage					15.00%	20.00%
Granted	0	0	73,672	0
Option Indexed to Issuer's Equity, Strike Price			$ 30.17
Equity-based compensation expense	$ 200		$ 300
2020 Plan \| Minimum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range	0.00%		0.00%			0.00%
2020 Plan \| Minimum [Member] \| Performance Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range	0.00%		0.00%		0.00%
2020 Plan \| Maximum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range	100.00%		100.00%			100.00%
2020 Plan \| Maximum [Member] \| Performance Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Performance stock options range	100.00%		100.00%		100.00%
2020 Plan \| Executive Officer [Member] \| Performance Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Granted		0		285,723
2020 ESPP
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares authorized for issuance under plan							445,653
Shares remaining available for future grants	2,716,358		2,716,358
Share-based compensation, description			The 2020 ESPP provides that the number of shares reserved and available for issuance will automatically increase on January 1, 2021 and each January 1 thereafter through January 1, 2030, by the lesser of (i) 438,898 shares of common stock, (ii) 1% of the Company’s outstanding number of shares of common stock on the immediately preceding December 31 or (iii) such lesser number of shares of common stock as determined by the administrator of the 2020 ESPP.
2020 ESPP \| Lesser of Potential Outcome 1
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Maximum number of shares to be issued, percentage			1.00%
Number of additional shares authorized			438,898
2018 Plan \| Restricted Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Granted			496,639