Segment Reporting - Schedule of Operating Expenses by Function (Details) - USD ($) |
3 Months Ended | 6 Months Ended | ||||
|---|---|---|---|---|---|---|
Jun. 30, 2026 |
Mar. 31, 2026 |
Jun. 30, 2025 |
Mar. 31, 2025 |
Jun. 30, 2026 |
Jun. 30, 2025 |
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| Revenue: | ||||||
| Collaboration revenue | $ 1,110,000 | $ 0 | $ 1,335,000 | $ 0 | ||
| Operating expenses: | ||||||
| Research and development | 16,603,000 | 17,370,000 | 31,447,000 | 38,446,000 | ||
| General and administrative | 5,406,000 | 6,712,000 | 10,853,000 | 13,174,000 | ||
| Impairment loss | 21,821,000 | 21,821,000 | 0 | |||
| Loss on lease termination, net | 1,368,000 | 1,368,000 | ||||
| Total operating expenses | 45,198,000 | 24,082,000 | 65,489,000 | 51,620,000 | ||
| Loss from operations | (44,088,000) | (24,082,000) | (64,154,000) | (51,620,000) | ||
| Other income, net: | ||||||
| Interest income | 697,000 | 815,000 | 1,491,000 | 1,449,000 | ||
| Other (loss) income, net | (2,000) | (16,000) | (2,000) | 24,000 | ||
| Total other income, net | 695,000 | 799,000 | 1,489,000 | 1,473,000 | ||
| Net loss before income tax expense | (43,393,000) | (23,283,000) | (62,665,000) | (50,147,000) | ||
| Income tax expense | 0 | 0 | 0 | 0 | ||
| Net loss | (43,393,000) | $ (19,272,000) | (23,283,000) | $ (26,864,000) | (62,665,000) | (50,147,000) |
| Clinical | ||||||
| Operating expenses: | ||||||
| Research and development | 5,202,000 | 5,397,000 | 10,578,000 | 11,345,000 | ||
| Manufacturing (pre-commercial) | ||||||
| Operating expenses: | ||||||
| Research and development | 3,852,000 | 4,077,000 | 7,317,000 | 9,524,000 | ||
| Research | ||||||
| Operating expenses: | ||||||
| Research and development | 3,820,000 | 4,182,000 | 6,778,000 | 10,102,000 | ||
| Other | ||||||
| Operating expenses: | ||||||
| Research and development | $ 3,729,000 | $ 3,714,000 | $ 6,774,000 | $ 7,475,000 | ||
| X | ||||||||||
- Definition Amount of write-down of assets recognized in the income statement. Includes, but is not limited to, losses from tangible assets, intangible assets and goodwill. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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| X | ||||||||||
- Definition Amount of gain (loss) on termination of lease before expiration of lease term. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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| X | ||||||||||
- Definition Amount of income (loss) from continuing operations, including income (loss) from equity method investments, before deduction of income tax expense (benefit), and income (loss) attributable to noncontrolling interest. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount before accretion (amortization) of purchase discount (premium) of interest income on nonoperating securities. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition The aggregate amount of income or expense from ancillary business-related activities (that is to say, excluding major activities considered part of the normal operations of the business). Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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| X | ||||||||||
- References No definition available.
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| X | ||||||||||
- Definition Generally recurring costs associated with normal operations except for the portion of these expenses which can be clearly related to production and included in cost of sales or services. Includes selling, general and administrative expense. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- References No definition available.
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| X | ||||||||||
- Definition The net result for the period of deducting operating expenses from operating revenues. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount of income (expense) related to nonoperating activities, classified as other. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- References No definition available.
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