Amounts owed under license agreement.

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- Definition

Payment of annual license fees and annual antibody program fees.

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Potential development regulatory and sales based milestone payments due.

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The potential amount of milestone payments due upon achievement of specified targets.

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Upfront and near term milestone payments due.

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Upfront payments due.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity.

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Commitments and Contingencies - Additional Information (Details) $ in Thousands, £ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2026 USD ($)	Jun. 30, 2025 USD ($)	Jun. 30, 2026 USD ($)	Jun. 30, 2025 USD ($)	Jun. 30, 2026 GBP (£)	Oct. 16, 2025 USD ($)
Other Commitments [Line Items]
Research and development expense	$ 48,686	$ 26,251	$ 83,214	$ 53,254
Leads License Agreement [Member]
Other Commitments [Line Items]
Upfront payment due						$ 38,000
Upfront and near-term milestone payments due	30,000		30,000			30,000
Potential milestone payments due						8,000
Research and development expense	100		100
Leads License Agreement [Member] \| Development Milestone [Member]
Other Commitments [Line Items]
Development and regulatory approval and sales based milestone due						$ 962,000
Alloy Therapeutics Llc [Member]
Other Commitments [Line Items]
Payment of annual license fees and program fees			50
Amounts owed under license agreement		100		100
Alloy Therapeutics Llc [Member] \| Development Milestone [Member] \| First Selected Antibody [Member] \| Maximum [Member]
Other Commitments [Line Items]
Potential milestone payments due	1,800		1,800
Alloy Therapeutics Llc [Member] \| Commercial Milestone [Member] \| First Selected Antibody [Member] \| Maximum [Member]
Other Commitments [Line Items]
Potential milestone payments due	11,000		11,000
Alloy Therapeutics Llc [Member] \| Milestone Payments [Member]
Other Commitments [Line Items]
Amounts owed under license agreement			0
IONTAS Limited [Member] \| Development Milestone [Member] \| First Development Program [Member]
Other Commitments [Line Items]
Potential milestone payments due	4,100		4,100		£ 3.1
IONTAS Limited [Member] \| Development Milestone [Member] \| Second Development Program [Member]
Other Commitments [Line Items]
Potential milestone payments due	3,300		3,300		2.5
IONTAS Limited [Member] \| Commercial Milestone [Member] \| First Development Program [Member]
Other Commitments [Line Items]
Potential milestone payments due	3,000		3,000		£ 2.3
IONTAS Limited [Member] \| Milestone Payments [Member]
Other Commitments [Line Items]
Research and development expense	$ 300	$ 200	$ 500	$ 400