3.26.1 html 195 249 1 true 53 0 false 7 false false R1.htm 75000 - Document - Document and Entity Information Sheet http://tyra.bio/20260630/taxonomy/role/Role_DocumentDocumentAndEntityInformation Document and Entity Information Cover 1 false false R2.htm 75010 - Statement - Condensed Balance Sheets (unaudited) Sheet http://tyra.bio/20260630/taxonomy/role/StatementCondensedBalanceSheetsUnaudited Condensed Balance Sheets (unaudited) Statements 2 false false R3.htm 75020 - Statement - Condensed Balance Sheets (unaudited) (Parenthetical) Sheet http://tyra.bio/20260630/taxonomy/role/StatementCondensedBalanceSheetsUnauditedParenthetical Condensed Balance Sheets (unaudited) (Parenthetical) Statements 3 false false R4.htm 75030 - Statement - Condensed Statements of Operations and Comprehensive Loss (unaudited) Sheet http://tyra.bio/20260630/taxonomy/role/StatementCondensedStatementsOfOperationsAndComprehensiveLossUnaudited Condensed Statements of Operations and Comprehensive Loss (unaudited) Statements 4 false false R5.htm 75050 - Statement - Condensed Statements of Stockholders' Equity (unaudited) Sheet http://tyra.bio/20260630/taxonomy/role/StatementCondensedStatementsOfStockholdersEquityUnaudited Condensed Statements of Stockholders' Equity (unaudited) Statements 5 false false R6.htm 75060 - Statement - Condensed Statements of Stockholders' Equity (unaudited) (Parenthetical) Sheet http://tyra.bio/20260630/taxonomy/role/StatementCondensedStatementsOfStockholdersEquityUnauditedParenthetical Condensed Statements of Stockholders' Equity (unaudited) (Parenthetical) Statements 6 false false R7.htm 75070 - Statement - Condensed Statements of Cash Flows (Unaudited) Sheet http://tyra.bio/20260630/taxonomy/role/StatementCondensedStatementsOfCashFlowsUnaudited Condensed Statements of Cash Flows (Unaudited) Statements 7 false false R8.htm 75100 - Statement - Condensed Statements of Cash Flows (unaudited) (Parenthetical) Sheet http://tyra.bio/20260630/taxonomy/role/StatementCondensedStatementsOfCashFlowsUnauditedParenthetical Condensed Statements of Cash Flows (unaudited) (Parenthetical) Statements 8 false false R9.htm 995410 - Disclosure - Pay vs Performance Disclosure Sheet http://xbrl.sec.gov/ecd/role/PvpDisclosure Pay vs Performance Disclosure Notes 9 false false R10.htm 995445 - Disclosure - Insider Trading Arrangements Sheet http://xbrl.sec.gov/ecd/role/InsiderTradingArrangements Insider Trading Arrangements Notes 10 false false R11.htm 995455 - Disclosure - Organization and Summary of Significant Accounting Policies Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureOrganizationAndSummaryOfSignificantAccountingPolicies Organization and Summary of Significant Accounting Policies Notes 11 false false R12.htm 995465 - Disclosure - Fair Value Measurements Sheet http://tyra.bio/20260630/taxonomy/role/Role_DisclosureFairValueMeasurements Fair Value Measurements Notes 12 false false R13.htm 995475 - Disclosure - Marketable Securities Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureMarketableSecurities Marketable Securities Notes 13 false false R14.htm 995495 - Disclosure - Accrued Expenses and Other Current Liabilities Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureAccruedExpensesAndOtherCurrentLiabilities Accrued Expenses and Other Current Liabilities Notes 14 false false R15.htm 995515 - Disclosure - Stockholders' Equity Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureStockholdersEquity Stockholders' Equity Notes 15 false false R16.htm 995525 - Disclosure - Equity Incentive Plans and Stock-Based Compensation Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureEquityIncentivePlansAndStockbasedCompensation Equity Incentive Plans and Stock-Based Compensation Notes 16 false false R17.htm 995535 - Disclosure - Net Loss Per Share Sheet http://tyra.bio/20260630/taxonomy/role/Role_DisclosureNetLossPerShare Net Loss Per Share Notes 17 false false R18.htm 995555 - Disclosure - Leases Sheet http://tyra.bio/20260630/taxonomy/role/Role_DisclosureLeases Leases Notes 18 false false R19.htm 995565 - Disclosure - Commitments and Contingencies Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureCommitmentsAndContingencies Commitments and Contingencies Notes 19 false false R20.htm 995575 - Disclosure - Segment Information Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureSegmentInformation Segment Information Notes 20 false false R21.htm 995595 - Disclosure - Subsequent Events Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureSubsequentEvents Subsequent Events Notes 21 false false R22.htm 995605 - Disclosure - Organization and Summary of Significant Accounting Policies (Policies) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureOrganizationAndSummaryOfSignificantAccountingPoliciesPolicies Organization and Summary of Significant Accounting Policies (Policies) Policies http://tyra.bio/20260630/taxonomy/role/DisclosureOrganizationAndSummaryOfSignificantAccountingPolicies 22 false false R23.htm 995615 - Disclosure - Fair Value Measurements (Tables) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureFairValueMeasurementsTables Fair Value Measurements (Tables) Tables http://tyra.bio/20260630/taxonomy/role/Role_DisclosureFairValueMeasurements 23 false false R24.htm 995625 - Disclosure - Marketable Securities (Tables) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureMarketableSecuritiesTables Marketable Securities (Tables) Tables http://tyra.bio/20260630/taxonomy/role/DisclosureMarketableSecurities 24 false false R25.htm 995645 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureAccruedExpensesAndOtherCurrentLiabilitiesTables Accrued Expenses and Other Current Liabilities (Tables) Tables http://tyra.bio/20260630/taxonomy/role/DisclosureAccruedExpensesAndOtherCurrentLiabilities 25 false false R26.htm 995655 - Disclosure - Stockholders' Equity (Tables) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureStockholdersEquityTables Stockholders' Equity (Tables) Tables http://tyra.bio/20260630/taxonomy/role/DisclosureStockholdersEquity 26 false false R27.htm 995665 - Disclosure - Equity Incentive Plans and Stock-Based Compensation (Tables) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureEquityIncentivePlansAndStockbasedCompensationTables Equity Incentive Plans and Stock-Based Compensation (Tables) Tables http://tyra.bio/20260630/taxonomy/role/DisclosureEquityIncentivePlansAndStockbasedCompensation 27 false false R28.htm 995675 - Disclosure - Net Loss Per Share (Tables) Sheet http://tyra.bio/20260630/taxonomy/role/Role_DisclosureNetLossPerShareTables Net Loss Per Share (Tables) Tables http://tyra.bio/20260630/taxonomy/role/Role_DisclosureNetLossPerShare 28 false false R29.htm 995685 - Disclosure - Leases (Tables) Sheet http://tyra.bio/20260630/taxonomy/role/Role_DisclosureLeasesTables Leases (Tables) Tables http://tyra.bio/20260630/taxonomy/role/Role_DisclosureLeases 29 false false R30.htm 995695 - Disclosure - Segment Information (Tables) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureSegmentInformationTables Segment Information (Tables) Tables http://tyra.bio/20260630/taxonomy/role/DisclosureSegmentInformation 30 false false R31.htm 995705 - Disclosure - Organization and Summary of Significant Accounting Policies - Additional Information (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureOrganizationAndSummaryOfSignificantAccountingPoliciesAdditionalInformationDetails Organization and Summary of Significant Accounting Policies - Additional Information (Details) Details 31 false false R32.htm 995725 - Disclosure - Fair Value Measurements - Summary of assets measured at fair value (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureFairValueMeasurementsSummaryOfAssetsMeasuredAtFairValueDetails Fair Value Measurements - Summary of assets measured at fair value (Details) Details 32 false false R33.htm 995735 - Disclosure - Marketable Securities - Summary of Available-for-Sale Securities and Gross Unrealized Losses (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureMarketableSecuritiesSummaryOfAvailableforsaleSecuritiesAndGrossUnrealizedLossesDetails Marketable Securities - Summary of Available-for-Sale Securities and Gross Unrealized Losses (Details) Details 33 false false R34.htm 995745 - Disclosure - Marketable Securities (Additional Information) (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureMarketableSecuritiesAdditionalInformationDetails Marketable Securities (Additional Information) (Details) Details http://tyra.bio/20260630/taxonomy/role/DisclosureMarketableSecuritiesTables 34 false false R35.htm 995755 - Disclosure - Property and Equipment - Schedule of Property and Equipment (Detail) Sheet http://tyra.bio/20260630/taxonomy/role/Role_DisclosurePropertyAndEquipmentScheduleOfPropertyAndEquipmentDetail Property and Equipment - Schedule of Property and Equipment (Detail) Details 35 false false R36.htm 995775 - Disclosure - Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureAccruedExpensesAndOtherCurrentLiabilitiesScheduleOfAccruedExpensesAndOtherCurrentLiabilitiesDetails Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Details) Details 36 false false R37.htm 995785 - Disclosure - Stockholders' Equity - Additional Information (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureStockholdersEquityAdditionalInformationDetails Stockholders' Equity - Additional Information (Details) Details 37 false false R38.htm 995795 - Disclosure - Stockholders' Equity - Summary of Reserved Shares of Common Stock (Details) - shares (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureStockholdersEquitySummaryOfReservedSharesOfCommonStockDetailsSharesDetails Stockholders' Equity - Summary of Reserved Shares of Common Stock (Details) - shares (Details) Details 38 false false R39.htm 995805 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Additional Information (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureEquityIncentivePlansAndStockbasedCompensationAdditionalInformationDetails Equity Incentive Plans and Stock-Based Compensation - Additional Information (Details) Details 39 false false R40.htm 995815 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Summary of Stock Option Activity (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureEquityIncentivePlansAndStockbasedCompensationSummaryOfStockOptionActivityDetails Equity Incentive Plans and Stock-Based Compensation - Summary of Stock Option Activity (Details) Details 40 false false R41.htm 995825 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Summary of Fair Value of Stock Option Grants (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureEquityIncentivePlansAndStockbasedCompensationSummaryOfFairValueOfStockOptionGrantsDetails Equity Incentive Plans and Stock-Based Compensation - Summary of Fair Value of Stock Option Grants (Details) Details 41 false false R42.htm 995835 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Summary of Company RSU activity (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureEquityIncentivePlansAndStockbasedCompensationSummaryOfCompanyRsuActivityDetails Equity Incentive Plans and Stock-Based Compensation - Summary of Company RSU activity (Details) Details 42 false false R43.htm 995845 - Disclosure - Equity Incentive Plans and Stock-Based Compensation - Summary of Stock-based Compensation Expense (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureEquityIncentivePlansAndStockbasedCompensationSummaryOfStockbasedCompensationExpenseDetails Equity Incentive Plans and Stock-Based Compensation - Summary of Stock-based Compensation Expense (Details) Details 43 false false R44.htm 995855 - Disclosure - Net Loss Per Share - Schedule of Basic and Diluted Net Loss Per Share (Detail) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureNetLossPerShareScheduleOfBasicAndDilutedNetLossPerShareDetail Net Loss Per Share - Schedule of Basic and Diluted Net Loss Per Share (Detail) Details 44 false false R45.htm 995865 - Disclosure - Net Loss Per Share - Schedule of Potentially Dilutive Securities Including All Outstanding Stock Options were excluded in Calculation of Diluted Shares Outstanding (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureNetLossPerShareScheduleOfPotentiallyDilutiveSecuritiesIncludingAllOutstandingStockOptionsWereExcludedInCalculationOfDilutedShar Net Loss Per Share - Schedule of Potentially Dilutive Securities Including All Outstanding Stock Options were excluded in Calculation of Diluted Shares Outstanding (Details) Details 45 false false R46.htm 995885 - Disclosure - Leases - Additional Information (Details) Sheet http://tyra.bio/20260630/taxonomy/role/Role_DisclosureLeasesAdditionalInformationDetails Leases - Additional Information (Details) Details 46 false false R47.htm 995895 - Disclosure - Leases - Schedule of Components of Lease Cost (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureLeasesScheduleOfComponentsOfLeaseCostDetails Leases - Schedule of Components of Lease Cost (Details) Details 47 false false R48.htm 995905 - Disclosure - Leases - Schedule of Maturities Lease Liabilities Weighted-Average Remaining Term and Weighted-Average Discount Rate (Details) Sheet http://tyra.bio/20260630/taxonomy/role/Role_DisclosureLeasesScheduleOfMaturitiesLeaseLiabilitiesWeightedAverageRemainingTermAndWeightedAverageDiscountRateDetails Leases - Schedule of Maturities Lease Liabilities Weighted-Average Remaining Term and Weighted-Average Discount Rate (Details) Details 48 false false R49.htm 995935 - Disclosure - Segment Information (Additional Information) (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureSegmentInformationAdditionalInformationDetails Segment Information (Additional Information) (Details) Details http://tyra.bio/20260630/taxonomy/role/DisclosureSegmentInformationTables 49 false false R50.htm 995945 - Disclosure - Segment Information - Schedule of Reconciliation of the Company's Net Loss (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureSegmentInformationScheduleOfReconciliationOfTheCompanysNetLossDetails Segment Information - Schedule of Reconciliation of the Company's Net Loss (Details) Details 50 false false R51.htm 995955 - Disclosure - Segment Information - Schedule of Reconciliation of the Company's Net Loss (Parenthetical) (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureSegmentInformationScheduleOfReconciliationOfTheCompanysNetLossParentheticalDetails Segment Information - Schedule of Reconciliation of the Company's Net Loss (Parenthetical) (Details) Details 51 false false R52.htm 995965 - Disclosure - Subsequent Events (Additional Information) (Details) Sheet http://tyra.bio/20260630/taxonomy/role/DisclosureSubsequentEventsAdditionalInformationDetails Subsequent Events (Additional Information) (Details) Details http://tyra.bio/20260630/taxonomy/role/DisclosureSubsequentEvents 52 false false All Reports Book All Reports tyra-20260630.htm tyra-20260630.xsd http://fasb.org/us-gaap/2026 http://xbrl.sec.gov/dei/2026 http://xbrl.sec.gov/ecd/2026 false false