Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
   Rule 13d-1(b)
   Rule 13d-1(c)
   Rule 13d-1(d)




schemaVersion:


SCHEDULE 13G




Comment for Type of Reporting Person:  These securities are held of record by TCG Crossover III (as defined in Item 2(a) below). TCG Crossover GP III (as defined in Item 2(a) below) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities. Based on 172,251,449 ordinary shares, as follows: (a) 49,290,234 ordinary shares outstanding as of May 19, 2026, as reported by the Issuer (as defined in Item 1(a) below) in its definitive proxy statement, filed with the United States Securities and Exchange Commission (the Commission) on June 3, 2026 (the Proxy Statement), plus (b) 122,961,215 ordinary shares issued in a private placement transaction that closed on July 28, 2026, as reported in the Issuer's Current Report on Form 8-K, filed with the Commission on July 28, 2026 (the Private Placement).


SCHEDULE 13G




Comment for Type of Reporting Person:  These securities are held of record by TCG Crossover III. TCG Crossover GP III is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities. Based on 172,251,449 ordinary shares, as follows: (a) 49,290,234 ordinary shares outstanding as of May 19, 2026, as reported by the Issuer in the Proxy Statement, plus (b) 122,961,215 ordinary shares issued in the Private Placement.


SCHEDULE 13G




Comment for Type of Reporting Person:  These securities are held of record by TCG Crossover III. TCG Crossover GP III is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities. Based on 172,251,449 ordinary shares, as follows: (a) 49,290,234 ordinary shares outstanding as of May 19, 2026, as reported by the Issuer in the Proxy Statement, plus (b) 122,961,215 ordinary shares issued in the Private Placement.


SCHEDULE 13G



 
TCG Crossover GP III, LLC
 
Signature:/s/ Craig Skaling
Name/Title:Craig Skaling, Authorized Signatory
Date:08/04/2026
 
TCG Crossover Fund III, L.P.
 
Signature:/s/ Craig Skaling
Name/Title:Craig Skaling, Authorized Signatory
Date:08/04/2026
 
Chen Yu
 
Signature:/s/ Craig Skaling
Name/Title:Craig Skaling, as Attorney-in-Fact for Chen Yu
Date:08/04/2026
Exhibit Information

Exhibit 1 - Joint Filing Agreement


ATTACHMENTS / EXHIBITS

ATTACHMENTS / EXHIBITS

EX-99.1