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    <element id="LPCN_ReportableSegmentMember" name="ReportableSegmentMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_LeadClinicalCandidateMember" name="LeadClinicalCandidateMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_OtherResearchAndDevelopmentProgramsMember" name="OtherResearchAndDevelopmentProgramsMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_LicenseFeeAndRoyaltiesReceivableCurrent" name="LicenseFeeAndRoyaltiesReceivableCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_RevenueRecognitionServicesLicensingFee" name="RevenueRecognitionServicesLicensingFee" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_StockIssuedDuringPeriodValueVestingOfRestrictedStockUnitsGross" name="StockIssuedDuringPeriodValueVestingOfRestrictedStockUnitsGross" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_StockIssuedDuringPeriodSharesVestingOfRestrictedStockUnitsGross" name="StockIssuedDuringPeriodSharesVestingOfRestrictedStockUnitsGross" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_IncreaseDecreaseInLicenseAndRoyaltiesReceivable" name="IncreaseDecreaseInLicenseAndRoyaltiesReceivable" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_DisclosureLeasesAbstract" name="DisclosureLeasesAbstract" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_BasisOfPresentationTable" name="BasisOfPresentationTable" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" />
    <element id="LPCN_BasisOfPresentationLineItems" name="BasisOfPresentationLineItems" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_LicenseFee" name="LicenseFee" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_PaymentsToBeMadeForLicenseFees" name="PaymentsToBeMadeForLicenseFees" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_PaymentReceivedForLicenseFee" name="PaymentReceivedForLicenseFee" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_DevelopmentAndSalesMilestonePaymentsReceived" name="DevelopmentAndSalesMilestonePaymentsReceived" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_PercentageOfRoyaltyPayment" name="PercentageOfRoyaltyPayment" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_LicenseRevenueNonoperating" name="LicenseRevenueNonoperating" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_EligibleDevelopmentAndSalesMilestonePaymentsToBeReceived" name="EligibleDevelopmentAndSalesMilestonePaymentsToBeReceived" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_CollaborativeArrangementRoyaltiesPercentageOfNetSales" name="CollaborativeArrangementRoyaltiesPercentageOfNetSales" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_PercentageOfRoyaltiesReductionBasedUponProductLaunch" name="PercentageOfRoyaltiesReductionBasedUponProductLaunch" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsAbstract" name="ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsAbstract" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_AggregateValueOfCommonStockSharesRegisteredForSale" name="AggregateValueOfCommonStockSharesRegisteredForSale" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_PercentageOfGrossProceedOnSaleOfShares" name="PercentageOfGrossProceedOnSaleOfShares" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_ProceedsFromIssuanceOfCommonStockGross" name="ProceedsFromIssuanceOfCommonStockGross" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_PercentageOfRoyalty" name="PercentageOfRoyalty" nillable="true" xbrli:periodType="instant" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_AgreementDescription" name="AgreementDescription" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_NonoperatingIncomeExpenseIncludingTaxes" name="NonoperatingIncomeExpenseIncludingTaxes" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="LPCN_NumberOfCommonSharesRegisteredForSale" name="NumberOfCommonSharesRegisteredForSale" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
</schema>
