Trading Arrangements, by Individual
Trading Arrangements, by Individual [Table]
Shares used in per share calculations:
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
Trading Arrangement:
Trading Arrangement [Axis]
Maximum
Maximum [Member]
Unrealized holding gains (losses) on marketable securities, tax
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment, Tax
New Hampshire
NEW HAMPSHIRE
Total assets
Offsetting Derivative Assets [Abstract]
Statistical Measurement [Domain]
Statistical Measurement [Domain]
Title of 12(b) Security
Title of 12(b) Security
Subsequent Event
Subsequent Event [Member]
Debt Securities, Available-for-sale [Table]
Debt Securities, Available-for-Sale [Table]
Document Fiscal Year Focus
Document Fiscal Year Focus
Gross Amounts Offset
Derivative Liability, Subject to Master Netting Arrangement, Asset Offset
Total stock-based compensation expense, net of tax
Share-Based Payment Arrangement, Expense, after Tax
Derivative Instruments, Gain (Loss) [Table]
Derivative Instruments, Gain (Loss) [Table]
Adjustment to Compensation, Amount
Adjustment to Compensation Amount
Financial Instrument [Axis]
Financial Instrument [Axis]
Debt covenant, consolidated leverage ratio
Debt Covenant, Consolidated Leverage Ratio
Consolidated leverage ratio that must be maintained in order to be in compliance with debt covenants.
Segment Reporting [Abstract]
Common stock, $0.01 par value; 500,000,000 shares authorized, 253,347,555 and 253,991,224 shares issued and outstanding, respectively
Common Stock, Value, Issued
Payments in connection with common stock withheld for employee tax obligations
Payment, Tax Withholding, Share-Based Payment Arrangement
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Table]
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Table]
Loss contingencies
Loss Contingency Accrual
Line of Credit
Line of Credit [Member]
Restatement Determination Date
Restatement Determination Date
Derivative Instrument [Axis]
Derivative Instrument [Axis]
Collaborative arrangement, allocation of research and development expenses, percent
Collaborative Arrangement, Allocation Of Research And Development Expenses, Percent
Collaborative Arrangement, Allocation Of Research And Development Expenses, Percent
Fair Value by Measurement Frequency [Axis]
Measurement Frequency [Axis]
Total cash equivalents and marketable securities, Gross Unrealized Gains
Cash Equivalents, Debt and Equity Securities, Unrealized Gain
Cash Equivalents, Debt and Equity Securities, Unrealized Gain
Amendment Flag
Amendment Flag
Marketed Products
Marketing-Related Intangible Assets [Member]
Current liabilities:
Liabilities, Current [Abstract]
Schedule of Cash Flow Hedging Instruments
Schedule of Notional Amounts of Outstanding Derivative Positions [Table Text Block]
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Gross
Unrealized
Losses
Gross unrealized loss
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
CASGEVY
CASGEVY [Member]
CASGEVY
Asset-backed securities
Asset-Backed Securities [Member]
Other comprehensive income (loss):
Other Comprehensive Income (Loss), Net of Tax [Abstract]
Adjustment to Non-PEO NEO Compensation Footnote
Adjustment to Non-PEO NEO Compensation Footnote [Text Block]
Schedule of Cash Equivalents
Schedule of Cash and Cash Equivalents [Table Text Block]
May 2025 Share Repurchase Program
May 2025 Share Repurchase Program [Member]
May 2025 Share Repurchase Program
Entity Address, State or Province
Entity Address, State or Province
Foreign currency translation adjustment
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent
PEO Total Compensation Amount
PEO Total Compensation Amount
Common stock, par value (in dollars per share)
Common Stock, Par or Stated Value Per Share
Financial instruments carried at fair value (asset positions):
Assets, Fair Value Disclosure [Abstract]
Reclassification out of Accumulated Other Comprehensive Income
Reclassification out of Accumulated Other Comprehensive Income [Member]
Cash equivalents
Cash and Cash Equivalents [Abstract]
Other intangible assets, net
Intangible assets, net (excluding goodwill), total
Intangible Asset, Excluding Goodwill, after Accumulated Amortization
Collaborative Arrangements by Agreement [Domain]
Collaborative Arrangements by Agreement [Domain]
Collaborative Arrangements by Agreement [Domain]
Accrued expenses
Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities
Share Repurchase Program [Domain]
Share Repurchase Program [Domain]
Notional amount of foreign currency forward contract
Derivative, Notional Amount
Basic (in shares)
Basic weighted-average common shares outstanding (in shares)
Weighted Average Number of Shares Outstanding, Basic
Outstanding Aggregate Erroneous Compensation Amount
Outstanding Aggregate Erroneous Compensation Amount
Total current liabilities
Liabilities, Current
Work-in-process
Inventory, Work in Process, Net of Reserves
Matures after five years
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, after Year 5 Through 10
Other current liabilities, Foreign currency forward contracts
Derivative Liability, Current
Pharmaceuticals
Pharmaceuticals [Member]
Pharmaceuticals
Other revenues
Collaborative and Royalty [Member]
Collaborative and Royalty [Member]
Entity Address, City or Town
Entity Address, City or Town
Share-based Compensation Arrangement by Share-based Payment Award
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Statement of Financial Position [Abstract]
Statement of Financial Position [Abstract]
Total cash equivalents and marketable securities, Gross Unrealized Losses
Cash Equivalents, Debt and Equity Securities, Unrealized Loss
Cash Equivalents, Debt and Equity Securities, Unrealized Loss
Award Timing MNPI Disclosure
Award Timing MNPI Disclosure [Text Block]
Basis of Presentation
Basis of Accounting, Policy [Policy Text Block]
Product revenues, net
Products
Product [Member]
Finite-lived intangible assets, net, total
Intangible Asset, Finite-Lived, after Accumulated Amortization
Peer Group Total Shareholder Return Amount
Peer Group Total Shareholder Return Amount
Corporate equity securities
Equity Securities, FV-NI and without Readily Determinable Fair Value [Abstract]
Crinetics
Crinetics [Member]
Crinetics
Accumulated Amortization
Intangible Asset, Finite-Lived, Accumulated Amortization
Level 2
Fair Value, Inputs, Level 2 [Member]
Total Shareholder Return Vs Peer Group
Total Shareholder Return Vs Peer Group [Text Block]
Line of credit facility, maximum borrowing capacity
Line of Credit Facility, Maximum Borrowing Capacity
Non-Rule 10b5-1 Arrangement Terminated
Non-Rule 10b5-1 Arrangement Terminated [Flag]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
United States
UNITED STATES
Subsequent Event Type [Axis]
Subsequent Event Type [Axis]
Stock-based compensation expense related to inventories
Share-Based Payment Arrangement, Amount Capitalized
Proceeds from upfront payment
Proceeds From Upfront Payment
Proceeds From Upfront Payment
Recently Issued Accounting Standards
New Accounting Pronouncements, Policy [Policy Text Block]
Schedule of Significant Segment Expenses
Segment Reporting [Table Text Block]
2026 Term Loan, Tranche Three
2026 Term Loan, Tranche Three [Member]
2026 Term Loan, Tranche Three
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Total other comprehensive income (loss)
Other comprehensive (loss) income, net of tax
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent
Matures after one year through five years
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, after Year One Through Five
Document Period End Date
Document Period End Date
Changes in operating assets and liabilities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Net cash used in investing activities
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Equity Awards Adjustments, Excluding Value Reported in Compensation Table
Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member]
Amount of credit agreement
Debt Instrument, Face Amount
Costs and expenses:
Costs and Expenses [Abstract]
Security Exchange Name
Security Exchange Name
Debt instrument, due period
Debt Instrument, Term
Business combination, total equity value
Business Combination, Price of Acquisition, Expected
Reclassification out of Accumulated Other Comprehensive Income [Domain]
Reclassification out of Accumulated Other Comprehensive Income [Domain]
Development expenses
Development Expenses
Development Expenses
Lessee, Lease, Description [Line Items]
Lessee, Lease, Description [Line Items]
Accumulated other comprehensive income (loss)
Accumulated Other Comprehensive Income (Loss), Net of Tax
Entity Shell Company
Entity Shell Company
Comprehensive Income (Loss), Net of Tax, Including Portion Attributable to Noncontrolling Interest [Abstract]
Statement of Comprehensive Income [Abstract]
Earnings Per Share
Earnings Per Share [Text Block]
Name
Outstanding Recovery, Individual Name
Net income per common share:
Earnings Per Share [Abstract]
Award Timing, How MNPI Considered
Award Timing, How MNPI Considered [Text Block]
Document Fiscal Period Focus
Document Fiscal Period Focus
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Peer Group Issuers, Footnote
Peer Group Issuers, Footnote [Text Block]
Schedule of Revenues by Product
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Table Text Block]
Total liabilities
Liabilities
Trading Symbol
Trading Symbol
Discount Rate
Measurement Input, Discount Rate [Member]
Geographical [Domain]
Geographical [Domain]
Indefinite-lived intangible assets
Intangible Asset, Excluding Goodwill, Indefinite-Lived
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member]
Pension Adjustments Prior Service Cost
Pension Adjustments Prior Service Cost [Member]
Company Selected Measure Name
Company Selected Measure Name
Purchases of available-for-sale debt securities
Payments to Acquire Debt Securities, Available-for-Sale
Amounts reclassified from accumulated other comprehensive income (loss)
Reclassification from AOCI, Current Period, Net of Tax, Attributable to Parent
Schedule of Restricted Cash
Restrictions on Cash and Cash Equivalents [Table Text Block]
Income Tax Disclosure [Abstract]
Income Tax Disclosure [Abstract]
Effect of potentially dilutive securities:
Weighted Average Number of Shares Outstanding, Diluted, Adjustment [Abstract]
Schedule of Indefinite-Lived Intangible Assets by Major Class [Table]
Intangible Asset, Indefinite-Lived [Table]
Swiss franc
Switzerland, Francs
Amortized Cost
Equity Securities, FV-NI, Cost
Credit Facility [Domain]
Credit Facility [Domain]
Stock-based compensation expense:
Share-based Compensation Allocation [Abstract]
-- None. No documentation exists for this element. --
Schedule of Cash Equivalents and Marketable Debt and Equity Securities
Cash, Cash Equivalent, and Investment [Table Text Block]
Cash flows from operating activities:
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Amortized Cost
Cash Equivalents And Debt Securities, Available for Sale
Cash Equivalents And Debt Securities, Available for Sale
Compensation Amount
Outstanding Recovery Compensation Amount
Individual:
Individual [Axis]
Intangible Asset, Indefinite-Lived [Line Items]
Intangible Asset, Indefinite-Lived [Line Items]
Diluted (in shares)
Diluted weighted-average common shares outstanding (in shares)
Weighted Average Number of Shares Outstanding, Diluted
Disaggregation of Revenue [Line Items]
Disaggregation of Revenue [Line Items]
Entity Emerging Growth Company
Entity Emerging Growth Company
Equity Valuation Assumption Difference, Footnote
Equity Valuation Assumption Difference, Footnote [Text Block]
ALYFTREK
ALYFTREK [Member]
ALYFTREK
Line of Credit Facility [Table]
Line of Credit Facility [Table]
Underlying Security Market Price Change
Underlying Security Market Price Change, Percent
Property and equipment, net
Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, after Accumulated Depreciation and Amortization
Commercial paper
Commercial Paper [Member]
Hedging
Derivative Instruments and Hedging Activities Disclosure [Text Block]
U.S. Treasury securities
US Treasury Securities [Member]
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Total liabilities
Gross Amounts Recognized
Derivative Liability, Subject to Master Netting Arrangement, before Offset
Award Timing Predetermined
Award Timing Predetermined [Flag]
Intangible Asset, Goodwill and Other [Abstract]
Intangible Asset, Goodwill and Other [Abstract]
Debt Securities, Available-for-sale [Line Items]
Debt Securities, Available-for-Sale [Line Items]
Adjustment To PEO Compensation, Footnote
Adjustment To PEO Compensation, Footnote [Text Block]
Stock-based compensation expense
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Level 1
Fair Value, Inputs, Level 1 [Member]
Other assets, Foreign currency forward contracts
Derivative Asset, Noncurrent
Effective tax rate
Effective Income Tax Rate Reconciliation, Percent
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Indefinite-lived Intangible Assets, Major Class Name [Domain]
Intangible Asset, Indefinite-Lived, Class [Domain]
Area of real estate property (in square feet)
Area of Real Estate Property
Total marketable available-for-sale debt securities
Debt Securities, Available-for-Sale [Abstract]
Share-based payment arrangements (in shares)
Incremental Common Shares Attributable to Dilutive Effect of Share-Based Payment Arrangements
Deferred income taxes
Increase (Decrease) in Other Deferred Liability
All Executive Categories
All Executive Categories [Member]
Pension Adjustments Service Cost
Pension Adjustments Service Cost [Member]
Preferred stock, par value (in dollars per share)
Preferred Stock, Par or Stated Value Per Share
Antidilutive Securities [Axis]
Antidilutive Securities [Axis]
Operating lease assets
Operating Lease, Right-of-Use Asset
Optional renewal term length
Lessee, Operating Lease, Renewal Term
Schedule of Computation of Basic and Diluted Net Income Per Common Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Fair Value Disclosures [Abstract]
Fair Value Disclosures [Abstract]
Royalty
Royalty [Member]
Debt Instrument, Name [Domain]
Debt Instrument, Name [Domain]
Issuance of common stock under benefit plans
Stock Issued During Period, Value, Employee Benefit Plan
Segment Information
Segment Reporting [Text Block]
Long-term line of credit
Long-Term Line of Credit
Minimum
Minimum [Member]
Expiration Date
Trading Arrangement Expiration Date
Hedging Relationship [Axis]
Hedging Relationship [Axis]
Effect of changes in exchange rates on cash
Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Prepaid expenses and other current assets
Restricted Cash and Cash Equivalent
Income Statement Location [Axis]
Location, Statement of Income, Balance [Axis]
Gross Amounts Not Offset
Derivative Asset, Subject to Master Netting Arrangement, Deduction of Financial Instrument Not Offset
Non-Rule 10b5-1 Arrangement Adopted
Non-Rule 10b5-1 Arrangement Adopted [Flag]
Legal Offset
Derivative Asset, Subject to Master Netting Arrangement, after Offset and Deduction
Cash equivalents
Cash and Cash Equivalents, Fair Value Disclosure
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member]
Total financial liabilities
Financial Liabilities Fair Value Disclosure
Aggregate Pension Adjustments Service Cost
Aggregate Pension Adjustments Service Cost [Member]
Derivative [Table]
Derivative [Table]
Common stock, shares authorized (in shares)
Common Stock, Shares Authorized
Estimated Useful Lives
Intangible Asset, Finite-Lived, Useful Life
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Antidilutive Security, Excluded EPS Calculation [Table]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Exercise Price
Award Exercise Price
Cash flows from investing activities:
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Recurring Basis
Fair Value, Recurring [Member]
Segment Reporting [Line Items]
Segment Reporting [Line Items]
Number of shares authorized to be repurchased
Share Repurchase Program, Authorized, Amount
Amortized Cost
Debt and Equity Securities, Cost
Debt and Equity Securities, Cost
Sales and maturities of available-for-sale debt securities
Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale
Document Quarterly Report
Document Quarterly Report
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member]
Segments [Domain]
Segments [Domain]
Collaborative Arrangements by Agreement [Axis]
Collaborative Arrangements by Agreement [Axis]
Significant terms of collaboration arrangements, by individual agreement.
Europe
Europe [Member]
Awards Close in Time to MNPI Disclosures, Table
Awards Close in Time to MNPI Disclosures [Table Text Block]
Equity Component [Domain]
Equity Component [Domain]
PEO Actually Paid Compensation Amount
PEO Actually Paid Compensation Amount
Measurement Input Type [Domain]
Measurement Input Type [Domain]
Total costs and expenses
Costs and Expenses
Adoption Date
Trading Arrangement Adoption Date
Euro
Euro Member Countries, Euro
Total shareholders’ equity
Beginning balance
Ending balance
Equity, Attributable to Parent
Fair Value
Equity Securities, FV-NI, Current
Assets
Assets [Abstract]
Title
Trading Arrangement, Individual Title
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost
Accounting Policies [Abstract]
Accounting Policies [Abstract]
Restatement does not require Recovery
Restatement Does Not Require Recovery [Text Block]
Insider Trading Policies and Procedures [Line Items]
2026 Term Loan
2026 Term Loan [Member]
2026 Term Loan
Other financing activities
Proceeds from (Payment for) Other Financing Activity
Insider Trading Policies and Procedures Adopted
Insider Trading Policies and Procedures Adopted [Flag]
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Derivative Instruments, Gain (Loss) [Line Items]
Derivative Instruments, Gain (Loss) [Line Items]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Selling, general and administrative expenses
Selling, General and Administrative Expense
Business Combination [Domain]
Business Combination [Domain]
Letters of Credit
Letter of Credit [Member]
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Geographical Area, Revenue and Long-Lived Asset [Line Items]
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Geographical Area, Revenue and Long-Lived Asset [Line Items]
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Compensation Actually Paid vs. Net Income
Compensation Actually Paid vs. Net Income [Text Block]
Antidilutive securities excluded from computation of earnings per share (in shares)
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Number of operating segments
Number of Operating Segments
Restricted stock units (including performance-based restricted stock units (“PSUs”))
Unvested restricted stock units (including PSUs)
Restricted Stock Units (RSUs) [Member]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Entity Central Index Key
Entity Central Index Key
Additional paid-in capital
Additional Paid in Capital, Common Stock
All Adjustments to Compensation
All Adjustments to Compensation [Member]
Business Combination [Axis]
Business Combination [Axis]
Equity [Abstract]
Equity [Abstract]
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member]
Net cash provided by operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Value of shares repurchased
Stock Repurchased During Period, Value, Net Of Tax
Stock Repurchased During Period, Value, Net Of Tax
Income Statement [Abstract]
Income Statement [Abstract]
Document Transition Report
Document Transition Report
Remaining milestone payment
Business Combination, Remaining Milestone Payment
Business Combination, Remaining Milestone Payment
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV [Axis]
Share Repurchase Program [Table]
Share Repurchase Program [Table]
Designated as Hedging Instruments
Designated as hedging instruments
Designated as Hedging Instrument [Member]
Deferred tax assets
Deferred Income Tax Assets, Net
Amount payable
Debt Instrument, Periodic Payment
Schedule of Provision for Income Taxes and Effective Tax rates
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
Proceeds from conversion of notes receivable
Proceeds from Collection of Notes Receivable
Stock Appreciation Rights (SARs)
Stock Appreciation Rights (SARs) [Member]
Intangible Asset, Finite-Lived
Intangible Asset, Finite-Lived [Table Text Block]
Schedule of Product Revenues by Geographic Location
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Geographical Area, Revenue and Long-Lived Asset [Table Text Block]
Basis spread on variable rate (as a percent)
Debt Instrument, Basis Spread on Variable Rate
City Area Code
City Area Code
Variable Rate [Domain]
Variable Rate [Domain]
Research expenses
Research Expenses
Research Expenses
Restricted stock units (including PSUs)
Restricted Stock [Member]
Accumulated Other Comprehensive Income (Loss)
Total
AOCI Attributable to Parent [Member]
All Individuals
All Individuals [Member]
Subsequent Events
Subsequent Events [Text Block]
Name
Forgone Recovery, Individual Name
Finished goods
Inventory, Finished Goods, Net of Reserves
Contingent consideration
Business Combination, Contingent Consideration, Liability, Noncurrent
Non-GAAP Measure Description
Non-GAAP Measure Description [Text Block]
Intangible Assets
Intangible Asset [Text Block]
Long-term marketable securities
Marketable Securities, Noncurrent
Statement [Line Items]
Statement
Statement [Line Items]
Total assets
Assets
Entity [Domain]
Entity [Domain]
Interest income, net
Interest income, net
Investment Income, Net
Preferred stock, shares issued (in shares)
Preferred Stock, Shares Issued
Schedule of Stock-based Compensation Expense by Line Item
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Equity securities without readily determinable fair value, amount
Equity Securities without Readily Determinable Fair Value, Amount
Gross
Unrealized
Gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Stock-based Compensation Expense and Share Repurchase Programs
Share-Based Payment Arrangement [Text Block]
Intangible asset impairment charge
Intangible asset impairment charge
Intangible Asset, Excluding Goodwill, Indefinite-Lived, Impairment Loss
Other comprehensive (loss) income before reclassifications
OCI, before Reclassifications, Net of Tax, Attributable to Parent
PEO
PEO [Member]
Fair Value
Cash Equivalents And Debt Securities, Available for Sale, Fair Value Disclosure
Cash Equivalents And Debt Securities, Available for Sale, Fair Value Disclosure
Total stock-based compensation expense included in “Total costs and expenses”
Share-Based Payment Arrangement, Expense
Gross Amounts Offset
Derivative Asset, Subject to Master Netting Arrangement, Liability Offset
Marketable securities
Marketable Securities, Current
Other long-term liabilities
Other Liabilities, Noncurrent
Goodwill
Goodwill
Assembled Workforce
Employment Contracts [Member]
Forgone Recovery due to Violation of Home Country Law, Amount
Forgone Recovery due to Violation of Home Country Law, Amount
Gross Amounts Not Offset
Derivative Liability, Subject to Master Netting Arrangement, Deduction of Financial Instrument Not Offset
Matures within one year
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One
Subsequent Event Type [Domain]
Subsequent Event Type [Domain]
Retained Earnings
Retained Earnings [Member]
Long-term operating lease liabilities
Operating Lease, Liability, Noncurrent
Revolving Credit Facility
Revolving Credit Facility [Member]
Contingent liabilities
Contingent Liabilities
Contingent Liabilities
On Available-For-Sale Debt Securities
AOCI, Accumulated Gain (Loss), Debt Securities, Available-for-Sale, Parent [Member]
Erroneously Awarded Compensation Recovery
Erroneously Awarded Compensation Recovery [Table]
Increase (Decrease) in Stockholders' Equity
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Common stock, shares outstanding (in shares)
Beginning balance (in shares)
Ending balance (in shares)
Common Stock, Shares, Outstanding
Award Timing Disclosures [Line Items]
Foreign Currency Translation Adjustment
Foreign Currency Forward Contract
Accumulated Foreign Currency Adjustment Attributable to Parent [Member]
Corporate debt securities
Corporate Debt Securities [Member]
Diluted (in dollars per share)
Diluted net income per common share (in dollars per share)
Earnings Per Share, Diluted
Accumulated Other Comprehensive Income (Loss) [Table]
Accumulated Other Comprehensive Income (Loss) [Table]
Entity Current Reporting Status
Entity Current Reporting Status
Net cash used in financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Total Shareholder Return Amount
Total Shareholder Return Amount
Common stock withheld for employee tax obligations
Share-Based Payment Arrangement, Decrease for Tax Withholding Obligation
Prepaid expenses and other assets
Increase (Decrease) in Prepaid Expense and Other Assets
Cash Flow Hedging
Cash Flow Hedging [Member]
Financial instruments carried at fair value (liability positions):
Liabilities, Fair Value Disclosure [Abstract]
Net unrealized (losses) gains
Unrealized Gain (Loss) on Investments
Line of Credit Facility [Line Items]
Line of Credit Facility [Line Items]
Schedule of Offsetting Assets
Offsetting Assets [Table Text Block]
Share-based Payment Arrangement [Abstract]
Share-Based Payment Arrangement [Abstract]
Cash flows from financing activities:
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Total revenues
Total product revenues, net
Revenue from Contract with Customer, Excluding Assessed Tax
British pound sterling
United Kingdom, Pounds
Financial Instruments [Domain]
Financial Instruments [Domain]
Total stock-based compensation expense included in “Total costs and expenses”
Share-Based Payment Arrangement, Expensed and Capitalized, Amount
Indemnification claims
Indemnification Claims
Amount of indemnification claims currently outstanding
Gross Amounts Presented
Derivative Asset
Inventories
Inventory Disclosure [Text Block]
Repurchases of common stock
Stock Repurchased During Period, Value
Indefinite-Lived Intangible Assets [Axis]
Intangible Asset, Finite-Lived, Class [Axis]
Equity Awards Adjustments, Footnote
Equity Awards Adjustments, Footnote [Text Block]
Share Repurchase Program [Line Items]
Share Repurchase Program [Line Items]
Underlying Securities
Award Underlying Securities Amount
Intangible assets, gross (excluding goodwill)
Intangible Asset, Excluding Goodwill, before Accumulated Amortization
Debt covenant, increase in consolidated leverage ratio
Debt Covenant, Increase In Consolidated Leverage Ratio
Debt Covenant, Increase In Consolidated Leverage Ratio
Schedule of Cash, Cash Equivalents and Available-for-sale Securities [Table]
Schedule of Cash, Cash Equivalents and Available-for-sale Securities [Table]
Schedule of the cash and cash equivalents and available-for-sale investments held by the entity.
Issuances of common stock under benefit plans
Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Including Option Exercised
Other investing activities
Payment for (Proceeds from) Other Investing Activity
Inventories
Increase (Decrease) in Inventories
Segment Reporting [Table]
Segment Reporting [Table]
Commitments and Contingencies Disclosure [Abstract]
Commitments and Contingencies Disclosure [Abstract]
All Trading Arrangements
All Trading Arrangements [Member]
Other Performance Measure, Amount
Other Performance Measure, Amount
Award Timing MNPI Considered
Award Timing MNPI Considered [Flag]
Income from operations
Operating Income (Loss)
Current Fiscal Year End Date
Current Fiscal Year End Date
JOURNAVX
JOURNAVX [Member]
JOURNAVX
Non-PEO NEO Average Total Compensation Amount
Non-PEO NEO Average Total Compensation Amount
Derivative [Line Items]
Derivative [Line Items]
Repurchase of common stock (in shares)
Shares repurchased (in shares)
Stock Repurchased During Period, Shares
Australian dollar
Australia, Dollars
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member]
Entity File Number
Entity File Number
Rule 10b5-1 Arrangement Adopted
Rule 10b5-1 Arrangement Adopted [Flag]
Corporate equity securities
Equity Securities [Member]
Recovery of Erroneously Awarded Compensation Disclosure [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Total cash equivalents and marketable securities, Amortized Cost
Cash Equivalents, Debt and Equity Securities, Cost
Cash Equivalents, Debt and Equity Securities, Cost
Common stock, shares issued (in shares)
Common Stock, Shares, Issued
Measure:
Measure [Axis]
Gross
Unrealized
Gains
Equity Securities, FV-NI, Unrealized Gain
Allowance for credit loss for available-for-sale debt securities
Debt Securities, Available-for-Sale, Allowance for Credit Loss
Accumulated Other Comprehensive Income (Loss)
Comprehensive Income (Loss) Note [Text Block]
Equity Components [Axis]
Equity Components [Axis]
Equity Components [Axis]
Accounts receivable
Increase (Decrease) in Accounts Receivable
Currency [Axis]
Currency [Axis]
Product and Service [Domain]
Product and Service [Domain]
Cash paid for income taxes
Income Tax Paid, after Refund Received
Schedule of Foreign Exchange Contracts
Schedule of Foreign Exchange Contracts, Statement of Financial Position [Table Text Block]
Disaggregation of Revenue [Table]
Disaggregation of Revenue [Table]
Entity Interactive Data Current
Entity Interactive Data Current
Variable Rate [Axis]
Variable Rate [Axis]
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract]
Compensation Actually Paid vs. Other Measure
Compensation Actually Paid vs. Other Measure [Text Block]
Entity Small Business
Entity Small Business
Comprehensive income
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
CRISPR
CRISPR [Member]
CRISPR
Termination Date
Trading Arrangement Termination Date
Common stock withheld for employee tax obligations (in shares)
Share-Based Payment Arrangement, Shares Withheld for Tax Withholding Obligation
Subsequent Events [Abstract]
Fair Value, Recurring and Nonrecurring [Table]
Fair Value, Recurring and Nonrecurring [Table]
Compensation Actually Paid vs. Total Shareholder Return
Compensation Actually Paid vs. Total Shareholder Return [Text Block]
MNPI Disclosure Timed for Compensation Value
MNPI Disclosure Timed for Compensation Value [Flag]
Other current liabilities
Other Liabilities, Current
Marketable securities:
Marketable Securities
Other assets
Other Assets, Noncurrent
Document Type
Document Type
Prepaid expenses and other current assets, Foreign currency forward contracts
Derivative Asset, Current
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Accrued expenses
Accrued Liabilities, Current
Fair Value as of Grant Date
Award Grant Date Fair Value
Intangible Asset, Indefinite-Lived
Intangible Asset, Indefinite-Lived [Table Text Block]
Summary of cash, cash equivalents and marketable securities
Schedule of Cash, Cash Equivalents and Available-for-sale Securities [Line Items]
-- None. No documentation exists for this element. --
Acquired in-process research and development expenses
Research and Development Asset Acquired in Transaction Other than Business Combination or Joint Venture Formation, Writeoff
Pay vs Performance Disclosure, Table
Pay vs Performance [Table Text Block]
Stock repurchase program, remaining amount
Share Repurchase Program, Remaining Authorized, Amount
Arrangement Duration
Trading Arrangement Duration
Subsequent Event [Line Items]
Subsequent Event [Line Items]
Statement of Stockholders' Equity [Abstract]
Statement of Stockholders' Equity [Abstract]
Local Phone Number
Local Phone Number
Additional Balance Sheet & Cash Flow Information
Additional Financial Information Disclosure [Text Block]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Registrant Name
Entity Registrant Name
Basis of Presentation and Accounting Policies
Organization, Consolidation, Basis of Presentation, Business Description and Accounting Policies [Text Block]
Insider Trading Policies and Procedures Not Adopted
Insider Trading Policies and Procedures Not Adopted [Text Block]
Commitments and contingencies (Note L)
Commitments and Contingencies
Finite-lived intangible assets, gross
Intangible Asset, Finite-Lived, before Accumulated Amortization
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name [Domain]
Changed Peer Group, Footnote
Changed Peer Group, Footnote [Text Block]
Reclassification out of Accumulated Other Comprehensive Income [Axis]
Reclassification out of Accumulated Other Comprehensive Income [Axis]
Other CF product revenues
Manufactured Product, Other [Member]
Forgone Recovery due to Expense of Enforcement, Amount
Forgone Recovery due to Expense of Enforcement, Amount
Executive Category:
Executive Category [Axis]
Non-U.S. Currency Loans
Non-U.S. Currency Loans [Member]
Non-U.S. Currency Loans
Liabilities and Shareholders’ Equity
Liabilities and Equity [Abstract]
Intangible Asset, Finite-Lived, Class [Domain]
Intangible Asset, Finite-Lived, Class [Domain]
Schedule of Financial Assets Subject to Fair Value Measurements
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Inventories
Total
Inventory, Net
Award Type [Domain]
Award Type [Domain]
Non-PEO NEO Average Compensation Actually Paid Amount
Non-PEO NEO Average Compensation Actually Paid Amount
Fair Value Measurements
Fair Value Disclosures [Text Block]
Level 3
Fair Value, Inputs, Level 3 [Member]
U.S. government agency securities
US Government Agencies Debt Securities [Member]
Total cash equivalents and marketable securities, Fair Value
Total cash equivalents and marketable securities, fair value
Cash Equivalents, Debt and Equity Securities, Fair Value
Cash Equivalents, Debt and Equity Securities, Fair Value
Supplemental disclosure of cash flow information:
Supplemental Cash Flow Information [Abstract]
February 2023 Share Repurchase Program
February 2023 Share Repurchase Program [Member]
February 2023 Share Repurchase Program
Schedule of Fair Value of Our Contingent Consideration Liabilities
Business Combination, Contingent Consideration [Table Text Block]
PEO Name
PEO Name
2026 Term Loan, Tranche One
2026 Term Loan, Tranche One [Member]
2026 Term Loan, Tranche One
Geographical [Axis]
Geographical [Axis]
Contract liabilities
Contract with Customer, Liability
On Foreign Currency Forward Contracts
Accumulated Gain (Loss), Net, Cash Flow Hedge, Parent [Member]
Other segment items
Segment Reporting, Other Segment Item, Amount
Stock Price or TSR Estimation Method
Stock Price or TSR Estimation Method [Text Block]
Entity Tax Identification Number
Entity Tax Identification Number
Contingent consideration, measurement input (percent)
Business Combination, Contingent Consideration, Liability, Measurement Input
Legal Entity [Axis]
Legal Entity [Axis]
Allocation of net profits and net losses, percent
Collaborative Arrangement, Allocation Of Net Profits And Losses, Percent
Collaborative Arrangement, Allocation Of Net Profits And Losses, Percent
Gross
Unrealized
Gains
Debt and Equity Securities, Unrealized Gain
Debt and Equity Securities, Unrealized Gain
Schedule of Credits Recognized in Condensed Consolidated Statements of Income (Loss)
Collaborative Arrangement and Arrangement Other than Collaborative [Table Text Block]
Income tax effect
Share-Based Payment Arrangement, Expense, Tax Benefit
Lessee, Lease, Description [Table]
Lessee, Lease, Description [Table]
2026 Term Loan, Tranche Two
2026 Term Loan, Tranche Two [Member]
2026 Term Loan, Tranche Two
Cash, cash equivalents and restricted cash—beginning of period
Cash, cash equivalents and restricted cash—end of period
Cash, cash equivalents and restricted cash per condensed consolidated statement of cash flows
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Accounts payable
Increase (Decrease) in Accounts Payable
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Base Rate
Base Rate [Member]
Aggregate Erroneous Compensation Not Yet Determined
Aggregate Erroneous Compensation Not Yet Determined [Text Block]
Legal Offset
Derivative Liability, Subject to Master Netting Arrangement, after Offset and Deduction
Schedule of Foreign Exchange Contracts, Condensed Consolidated Statements of Operations
Reclassification out of Accumulated Other Comprehensive Income [Table Text Block]
Material Terms of Trading Arrangement
Material Terms of Trading Arrangement [Text Block]
Non-NEOs
Non-NEOs [Member]
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member]
Debt Instrument [Axis]
Debt Instrument [Axis]
Measurement Frequency [Domain]
Measurement Frequency [Domain]
Subsequent Event [Table]
Subsequent Event [Table]
Stock-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
ESPP share issuances
Employee Stock [Member]
Schedule of Inventories by Type
Schedule of Inventory, Current [Table Text Block]
Long-Term Debt, Type [Domain]
Long-Term Debt, Type [Domain]
Basic (in dollars per share)
Basic net income per common share (in dollars per share)
Earnings Per Share, Basic
TRIKAFTA/KAFTRIO
TRIKAFTA/KAFTRIO [Member]
TRIKAFTA/KAFTRIO [Member]
Measurement Input Type [Axis]
Measurement Input Type [Axis]
Repurchases of common stock
Payments for Repurchase of Common Stock
Total current assets
Assets, Current
Statistical Measurement [Axis]
Statistical Measurement [Axis]
Insider Trading Arrangements [Line Items]
Business combination, price per share, expected
Business Combination, Price Per Share, Expected
Business Combination, Price Per Share, Expected
Other
Other Countries Outside of the United States and Europe [Member]
Other Countries Outside of the United States and Europe [Member]
Award Type [Axis]
Award Type [Axis]
Named Executive Officers, Footnote
Named Executive Officers, Footnote [Text Block]
Accounts receivable, net
Accounts Receivable, after Allowance for Credit Loss, Current
Retained earnings
Retained Earnings (Accumulated Deficit)
Unrealized holding (losses) gains on available-for-sale debt securities, net of tax of $4.9, $(2.1), $13.7 and $(6.7), respectively
Other Comprehensive Income (Loss), Available-for-Sale Securities Adjustment, Net of Tax, Portion Attributable to Parent
Product and Service [Axis]
Product and Service [Axis]
All Currencies [Domain]
All Currencies [Domain]
Unrealized gains (losses) on foreign currency forward contracts, net of tax of $(11.2), $54.1, $(35.1) and $79.7, respectively
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification and Tax, Parent
Change in fair value of contingent consideration
Increase in fair value of contingent payments
Business Combination, Contingent Consideration, Change in Contingent Consideration, Liability, Increase (Decrease)
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member]
Awards Close in Time to MNPI Disclosures
Awards Close in Time to MNPI Disclosures [Table]
Proceeds from Issuance of Secured Debt
Proceeds from Issuance of Secured Debt
Common Stock
Common Stock [Member]
Fair Value
Total
Debt Securities, Available-for-Sale
Contingent consideration liabilities
Beginning balance
Ending balance
Business Combination, Contingent Consideration, Liability
Compensation Actually Paid vs. Company Selected Measure
Compensation Actually Paid vs. Company Selected Measure [Text Block]
Cover [Abstract]
Cover [Abstract]
Number of reportable segments not disclosed flag
Number Of Reportable Segments Not Disclosed Flag
Number Of Reportable Segments Not Disclosed Flag
Total revenues outside of the United States
Non-US [Member]
Derivative Contract [Domain]
Derivative Contract [Domain]
Equity Awards Adjustments
Equity Awards Adjustments [Member]
Collaboration, License and Other Arrangements
Collaborative Arrangement Disclosure [Text Block]
Hedging Relationship [Domain]
Hedging Relationship [Domain]
Realized gain (loss) amount
Debt Securities, Available-for-Sale, Realized Gain (Loss)
Foreign currency forward contracts
Derivative Liability, Noncurrent
Total liabilities and shareholders’ equity
Liabilities and Equity
Realized gain on investments
Realized Investment Gains (Losses)
Stock options
Stock options
Share-Based Payment Arrangement, Option [Member]
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Geographical Area, Revenue and Long-Lived Asset [Table]
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Geographical Area, Revenue and Long-Lived Asset [Table]
Segments [Axis]
Segments [Axis]
Other liabilities
Increase (Decrease) in Other Operating Liabilities
Additional 402(v) Disclosure
Additional 402(v) Disclosure [Text Block]
Inventory Disclosure [Abstract]
Inventory Disclosure [Abstract]
Tabular List, Table
Tabular List [Table Text Block]
Schedule of Company's Net Unrealized Gains (Losses) on Corporate Equity Securities
Unrealized Gain (Loss) on Investments [Table Text Block]
Other income (expense), net
Other income (expense), net
Other Nonoperating Income (Expense)
Royalty burden (as a percent)
Royalty Burden, Percentage
Royalty Burden, Percentage
Gross
Unrealized
Losses
Equity Securities, FV-NI, Unrealized Loss
Name
Awards Close in Time to MNPI Disclosures, Individual Name
Shareholders’ equity:
Equity, Including Portion Attributable to Noncontrolling Interest [Abstract]
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member]
General and administrative expenses
General and Administrative Expense
Preferred stock, shares authorized (in shares)
Preferred Stock, Shares Authorized
Preferred stock, $0.01 par value; 1,000,000 shares authorized; none issued
Preferred Stock, Value, Issued
Adjustment to Compensation:
Adjustment to Compensation [Axis]
Share Repurchase Program [Axis]
Share Repurchase Program [Axis]
Hedging Designation [Domain]
Hedging Designation [Domain]
Rule 10b5-1 Arrangement Terminated
Rule 10b5-1 Arrangement Terminated [Flag]
Aggregate Erroneous Compensation Amount
Aggregate Erroneous Compensation Amount
Cash paid for interest
Interest Paid, Excluding Capitalized Interest, Operating Activity
Statement of Cash Flows [Abstract]
Statement of Cash Flows [Abstract]
Hedging Designation [Axis]
Hedging Designation [Axis]
Foreign currency forward contracts
Foreign Exchange Forward [Member]
In-process research and development
In Process Research and Development [Member]
Fair Value
Debt and Equity Securities, Fair Value
Debt and Equity Securities, Fair Value
Credit Facility [Axis]
Credit Facility [Axis]
Aggregate Available
Trading Arrangement, Securities Aggregate Available Amount
Total financial assets
Assets, Fair Value Disclosure
Total CF product revenues, net
Cystic Fibrosis Products [Member]
Cystic Fibrosis Products
Canadian dollar
Canada, Dollars
Unrealized (losses) gains on foreign currency forward contracts, tax
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification, Tax, Parent
Name
Measure Name
Income Taxes
Income Tax Disclosure [Text Block]
Accounts payable
Accounts Payable, Current
Pay vs Performance Disclosure [Line Items]
Fair Value, Measurements, Fair Value Hierarchy [Domain]
Fair Value Hierarchy and NAV [Domain]
Other non-cash items, net
Other Noncash Income (Expense)
Issuance of common stock under benefit plans (in shares)
Stock Issued During Period, Shares, Employee Benefit Plan
Pay vs Performance Disclosure
Pay vs Performance Disclosure [Table]
Additional Paid-in Capital
Additional Paid-in Capital [Member]
Entity Filer Category
Entity Filer Category
Debt securities fair value, unrealized loss position
Debt Securities, Available-for-Sale, Unrealized Loss Position
Indefinite-lived Intangible Assets [Axis]
Intangible Asset, Indefinite-Lived, Class [Axis]
Gross
Unrealized
Losses
Debt and Equity Securities, Unrealized Loss
Debt and Equity Securities, Unrealized Loss
Schedule of Offsetting Liabilities
Offsetting Liabilities [Table Text Block]
Name
Trading Arrangement, Individual Name
Selling and other commercial expenses
Selling Expense
Cash and cash equivalents
Cash and Cash Equivalent
Raw materials
Inventory, Raw Materials, Net of Reserves
Company Selected Measure Amount
Company Selected Measure Amount
Not Designated as Hedging Instrument
Not designated as hedging instruments
Not Designated as Hedging Instrument [Member]
Investments, Debt and Equity Securities [Abstract]
Investments, Debt and Equity Securities [Abstract]
Depreciation and amortization expense
Depreciation, Depletion and Amortization
SOFR Loan
Secured Overnight Financing Rate (SOFR) [Member]
Commercial paper
Commercial Paper, Not Included with Cash and Cash Equivalents [Member]
Net unrecognized tax benefits which would affect the tax rate if recognized
Unrecognized Tax Benefits that Would Impact Effective Tax Rate
Current assets:
Assets, Current [Abstract]
Gross Amounts Presented
Derivative Liability
Non-PEO NEO
Non-PEO NEO [Member]
Line of credit facility additional borrowing capacity
Line Of Credit Facility Additional Borrowing Capacity
Amount of increased borrowing capacity available in the future.
Entity Address, Address Line One
Entity Address, Address Line One
Right-of-use operating lease assets
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Provision for income taxes
Provision for income taxes
Income Tax Expense (Benefit)
Adjustments to reconcile net income to net cash provided by operating activities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Noncash Item [Abstract]
Cost of sales
Cost of Product and Service Sold
Award Timing Method
Award Timing Method [Text Block]
Net increase in cash, cash equivalents and restricted cash
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Total liabilities
Offsetting Derivative Liabilities [Abstract]
Marketable Securities and Other Investments
Cash, Cash Equivalent, and Marketable Security [Text Block]
Forgone Recovery, Explanation of Impracticability
Forgone Recovery, Explanation of Impracticability [Text Block]
Research and development expenses
Research and development expenses
Research and Development Expense (Excluding Acquired in Process Cost)
AOCI Attributable to Parent, Net of Tax [Roll Forward]
AOCI Attributable to Parent, Net of Tax [Roll Forward]
Net income
Net income
Net income
Net Income (Loss) Attributable to Parent
Long-Term Debt, Type [Axis]
Long-Term Debt, Type [Axis]
Erroneous Compensation Analysis
Erroneous Compensation Analysis [Text Block]
Bridge Loan
Bridge Loan [Member]
Balance Sheet Location [Axis]
Location, Statement of Financial Position, Balance [Axis]
Statement [Table]
Statement [Table]
Restatement Determination Date:
Restatement Determination Date [Axis]
Schedule of Accumulated Other Comprehensive Income (Loss)
Schedule of Accumulated Other Comprehensive Income (Loss) [Table Text Block]
Certificates of deposit
Certificates of Deposit [Member]
Derivative term
Derivative, Contract Term
Total assets
Gross Amounts Recognized
Derivative Asset, Subject to Master Netting Arrangement, before Offset
CRISPR JDCA
CRISPR JDCA [Member]
CRISPR joint development and commercialization agreement
Pension Benefits Adjustments, Footnote
Pension Benefits Adjustments, Footnote [Text Block]
Derivative Instruments and Hedging Activities Disclosure [Abstract]
Derivative Instruments and Hedging Activities Disclosure [Abstract]