v3.26.1
Segment Information - Schedule of Revenues by Product (Details) - USD ($)
$ in Millions
 3 Months Ended 6 Months Ended 18 Months Ended
Jun. 30, 2026
Jun. 30, 2025
Jun. 30, 2026
Jun. 30, 2025
Jun. 30, 2026
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]          
Total product revenues, net $ 3,333.9 $ 2,964.7 $ 6,320.8 $ 5,734.9  
Total CF product revenues, net          
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]          
Total product revenues, net 3,207.9 2,901.6 6,122.9 5,646.3  
TRIKAFTA/KAFTRIO          
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]          
Total product revenues, net 2,497.2 2,551.1 4,851.9 5,086.6  
ALYFTREK          
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]          
Total product revenues, net 573.6 156.8 998.0 210.7 $ 1,800.0
Other CF product revenues          
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]          
Total product revenues, net 137.1 193.7 273.0 349.0  
CASGEVY          
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]          
Total product revenues, net 76.4 30.4 119.3 44.6  
JOURNAVX          
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]          
Total product revenues, net 49.6 12.0 78.6 13.3  
Product revenues, net          
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]          
Total product revenues, net $ 3,333.9 $ 2,944.0 $ 6,320.8 $ 5,704.2