v3.26.1
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Millions
6 Months Ended
Jun. 30, 2026
Jun. 30, 2025
Operating activities    
Net income (loss) $ 485.9 $ (811.0)
Adjustments to reconcile net income (loss) to net cash provided by operating activities:    
Intangible asset amortization 342.3 316.5
Share-based compensation 147.8 132.2
Acquired in-process research and development 77.0 905.4
Acquisition accounting inventory fair value step-up adjustment 54.1 67.0
Provision for losses on accounts receivable and inventory 21.7 6.8
Depreciation 18.2 22.3
Non-cash interest expense 9.6 21.9
Deferred tax benefit (104.9) (110.3)
Gain on sale of priority review voucher (122.8) 0.0
Other non-cash transactions 1.5 7.0
Changes in assets and liabilities:    
Accounts receivable (51.4) 10.5
Inventories (107.7) (61.9)
Prepaid expenses and other assets 56.8 19.9
Accounts payable 7.1 6.5
Accrued liabilities 0.6 (75.4)
Income taxes payable (0.3) 59.3
Other liabilities (11.6) 1.9
Net cash provided by operating activities 823.9 518.6
Investing activities    
Proceeds from maturity of investments 1,240.0 780.0
Proceeds from sale of priority review voucher 200.0 0.0
Payments related to sale of priority review voucher (77.2) 0.0
Purchases of property, plant and equipment (37.8) (26.8)
Acquired in-process research and development (77.0) 0.0
Acquisition of investments (770.0) (680.1)
Acquisition of intangible assets 0.0 (25.0)
Asset acquisition, net of cash acquired 0.0 (858.1)
Net cash provided by (used in) investing activities 478.0 (810.0)
Financing activities    
Repayment of 2026 Notes (1,000.0) 0.0
Payment of employee withholding taxes related to share-based awards (113.1) (69.4)
Repayments of long-term debt (15.5) (765.5)
Proceeds from employee equity incentive and purchase plans 55.6 22.0
Share repurchases 0.0 (125.0)
Net cash used in financing activities (1,073.0) (937.9)
Effect of exchange rates on cash and cash equivalents (1.0) 6.3
Net increase (decrease) in cash and cash equivalents 227.9 (1,223.0)
Cash and cash equivalents, at beginning of period 1,391.9 2,412.9
Cash and cash equivalents, at end of period $ 1,619.8 $ 1,189.9