v3.26.1
Insider Trading Arrangements
 3 Months Ended
Jun. 30, 2026
shares
Trading Arrangements, by Individual  
Material Terms of Trading Arrangement
The following is a summary of the material terms of the contracts, instructions or written plans for the purchase or sale of the Company’s securities adopted or terminated by our officers (as defined in Rule 16a-1(f) under the Exchange Act) and directors during the quarter ended June 30, 2026:
Type of Trading Arrangement
Name and Position
Date
Action
Rule 10b5-1*
Expiration Date
Total Ordinary Shares to be Sold
Robert Iannone
(Executive Vice President, Global Head of Research and Development, Chief Medical Officer)
5/28/2026AdoptionX
5/28/2027, or such earlier date upon which all transactions are completed or expire without execution
Indeterminable(1)
Renee D. Gala
(President and Chief Executive Officer)
6/4/2026AdoptionX
8/5/2027, or such earlier date upon which all transactions are completed
Up to 7,400
Mark D. Smith
(Director)
6/15/2026TerminationX12/31/20261,157
* Contract, instruction or written plan intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) under the Exchange Act
(1) Dr. Iannone's Rule 10b5-1 Trading Plan provides for the (i) same-day exercise and sale of up to 53,700 stock options, (ii) sale of up to 16,038 ordinary shares, (iii) sale of an indeterminable number of ordinary shares sufficient to cover stock option exercise costs and estimated tax withholding amounts and customary brokerage fees, and (iv) sale of an indeterminable number of ordinary shares from the settlement of RSUs and PSUs. The number of ordinary shares in clauses (iii) and (iv) are indeterminable because the numbers will vary based on the extent to which vesting, performance or exercise conditions are satisfied, the market price of the Company's ordinary shares at the time of settlement and the number of shares that would otherwise be issuable on each settlement date of a covered stock option, RSU or PSU that are sold or withheld in an amount sufficient to satisfy the applicable tax withholding obligations.
Non-Rule 10b5-1 Arrangement Adopted false
Non-Rule 10b5-1 Arrangement Terminated false
Robert Iannone [Member]  
Trading Arrangements, by Individual  
Name Robert Iannone
Title Executive Vice President, Global Head of Research and Development, Chief Medical Officer
Rule 10b5-1 Arrangement Adopted true
Adoption Date 5/28/2026
Expiration Date 5/28/2027
Arrangement Duration 365 days
Renee D. Gala [Member]  
Trading Arrangements, by Individual  
Name Renee D. Gala
Title President and Chief Executive Officer
Rule 10b5-1 Arrangement Adopted true
Adoption Date 6/4/2026
Expiration Date 8/5/2027
Arrangement Duration 427 days
Aggregate Available 7,400
Mark D. Smith [Member]  
Trading Arrangements, by Individual  
Name Mark D. Smith
Title Director
Rule 10b5-1 Arrangement Terminated true
Termination Date 6/15/2026
Aggregate Available 1,157