v3.26.1
Segment Reporting - Schedule of Segment Revenue Reconciled to Consolidated Net Loss (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2026
Jun. 30, 2025
Jun. 30, 2026
Jun. 30, 2025
Segment Reporting [Line Items]        
Total revenue $ 25,118 $ 1,031 $ 35,852 $ 1,392
Less:        
Cost of Revenue (154) 0 (354) 0
Research and development        
Total research and development expenses (99,850) (80,301) (199,931) (156,541)
Selling, general and administrative        
Total other income, net 11,604 13,475 24,137 28,106
Net loss (120,855) (115,637) (248,700) (212,411)
Product revenue, net        
Segment Reporting [Line Items]        
Total revenue 24,038 0 34,344 0
Collaboration and license revenue        
Segment Reporting [Line Items]        
Total revenue 1,080 1,031 1,508 1,392
Reportable Segment        
Segment Reporting [Line Items]        
Total revenue 25,118 1,031 35,852 1,392
Less:        
Cost of Revenue (154) 0 (354) 0
Research and development        
Paltusotine (13,702) (14,478) (25,571) (31,729)
Atumelnant (24,806) (11,161) (45,073) (18,910)
Other research and development programs (8,892) (9,607) (18,559) (16,665)
Research and development personnel expenses (29,330) (25,138) (59,979) (50,765)
Research and development stock-based compensation (14,004) (13,099) (33,332) (24,918)
Other research and development (9,116) (6,818) (17,417) (13,554)
Total research and development expenses (99,850) (80,301) (199,931) (156,541)
Selling, general and administrative        
Other selling, general and administrative expenses (26,299) (23,471) (46,741) (38,245)
Selling, general and administrative personnel expenses (20,397) (13,346) (40,434) (25,439)
Selling, general and administrative stock-based compensation (10,877) (13,025) (21,229) (21,684)
Total selling, general and administrative expenses (57,573) (49,842) (108,404) (85,368)
Total other income, net 11,604 13,475 24,137 28,106
Net loss (120,855) (115,637) (248,700) (212,411)
Reportable Segment | Product revenue, net        
Segment Reporting [Line Items]        
Total revenue 24,038 0 34,344 0
Reportable Segment | Collaboration and license revenue        
Segment Reporting [Line Items]        
Total revenue $ 1,080 $ 1,031 $ 1,508 $ 1,392