Equity Incentive Plans (Tables)
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6 Months Ended |
Jun. 30, 2026 |
| Share-Based Payment Arrangement [Abstract] |
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| Schedule of Stock Option Plans |
Our stock option activity during the six months ended June 30, 2026 was as follows: | | | | | | | | | | | | | | | | | | | | | | | | | Options Outstanding | | Weighted- Average Exercise Price | | Weighted- Average Remaining Term (in years) | | Aggregate Intrinsic Value (000’s) | | Balance at December 31, 2025 | 13,631,074 | | $ | 29.54 | | | | | | | Granted | 2,061,977 | | $ | 43.03 | | | | | | | Exercised | (629,013) | | $ | 23.27 | | | | | | | Forfeited and expired | (535,854) | | $ | 39.31 | | | | | | | Balance at June 30, 2026 | 14,528,184 | | $ | 31.37 | | | 7.0 | | $ | 126,176 | | | Exercisable at June 30, 2026 | 8,677,703 | | $ | 26.64 | | | 6.0 | | $ | 107,911 | |
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| Schedule of Restricted Stock Units |
Our RSU activity during the six months ended June 30, 2026, was as follows: | | | | | | | | | | | | | Restricted Stock Units Outstanding | | Weighted-Average Grant Date Fair Value | | Balance at December 31, 2025 | 2,321,732 | | | $ | 35.23 | | | Granted | 1,352,622 | | | $ | 42.92 | | | Vested | (682,005) | | | $ | 33.33 | | | Forfeited | (201,352) | | | $ | 37.67 | | | Balance at June 30, 2026 | 2,790,997 | | | $ | 39.24 | |
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| Schedule of Stock-Based Compensation Expense |
Stock-based compensation expense for all equity awards is reported in the condensed consolidated statements of operations and comprehensive income (loss) as follows: | | | | | | | | | | | | | | | | | | | | | | | | | Three months ended June 30, | | Six months ended June 30, | | 2026 | | 2025 | | 2026 | | 2025 | | Research and development | $ | 14,004 | | | $ | 13,099 | | | $ | 33,332 | | | $ | 24,918 | | | Selling, general and administrative | 10,877 | | | 13,025 | | | 21,229 | | | 21,684 | | | Total stock-based compensation expense (exclusive of capitalized stock-based compensation expense) | 24,881 | | | 26,124 | | | 54,561 | | | 46,602 | | | Capitalized stock-based compensation expense | 66 | | | — | | | 200 | | | — | | | Total stock-based compensation expense | $ | 24,947 | | | $ | 26,124 | | | $ | 54,761 | | | $ | 46,602 | |
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| Schedule of Unrecognized Stock-Based Compensation Expense |
A summary of our total unrecognized stock-based compensation expense, as of June 30, 2026, is as follows: | | | | | | | | | | | | | Unrecognized Stock-Based Compensation Expense | | Average Remaining Vesting Period (in years) | | Stock option awards | $ | 136,699 | | | 2.5 | | RSU awards | $ | 97,548 | | | 3.0 | | ESPP | $ | 3,770 | | | 1.0 |
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