| Summary of Segment Information |
The following table reconciles segment direct profit or loss to the Company’s condensed consolidated results (in thousands):
|
|
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|
|
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|
|
|
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|
|
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|
|
|
Three Months Ended June 30, |
|
|
Six Months Ended June 30, |
|
|
|
2026 |
|
|
2025 |
|
|
2026 |
|
|
2025 |
|
Revenue |
|
$ |
9,325 |
|
|
$ |
13,817 |
|
|
$ |
15,554 |
|
|
$ |
172,386 |
|
Zorevunersen(1) |
|
|
28,243 |
|
|
|
11,382 |
|
|
|
48,097 |
|
|
|
29,056 |
|
ADOA(1) |
|
|
2,697 |
|
|
|
1,747 |
|
|
|
4,555 |
|
|
|
2,140 |
|
SYNGAP1(1) |
|
|
1,073 |
|
|
|
818 |
|
|
|
1,818 |
|
|
|
1,160 |
|
MECP2(1) |
|
|
— |
|
|
|
(200 |
) |
|
|
— |
|
|
|
(53 |
) |
Other external program costs |
|
|
3,990 |
|
|
|
1,841 |
|
|
|
7,169 |
|
|
|
3,670 |
|
Payroll and other personnel costs - R&D (2) |
|
|
18,218 |
|
|
|
11,618 |
|
|
|
34,336 |
|
|
|
22,629 |
|
Payroll and other personnel costs - SG&A (2) |
|
|
13,318 |
|
|
|
8,979 |
|
|
|
24,375 |
|
|
|
17,908 |
|
Other non-program costs - R&D (3) |
|
|
1,628 |
|
|
|
1,615 |
|
|
|
3,308 |
|
|
|
3,022 |
|
Other non-program costs - SG&A (3) |
|
|
5,587 |
|
|
|
3,317 |
|
|
|
10,742 |
|
|
|
8,914 |
|
Interest expense |
|
|
(17 |
) |
|
|
(3 |
) |
|
|
(41 |
) |
|
|
(3 |
) |
Interest income |
|
|
3,520 |
|
|
|
3,792 |
|
|
|
6,939 |
|
|
|
6,681 |
|
Other income |
|
|
308 |
|
|
|
28 |
|
|
|
327 |
|
|
|
57 |
|
Provision for income taxes |
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
(1,278 |
) |
Segment net income (loss) |
|
$ |
(61,618 |
) |
|
$ |
(23,483 |
) |
|
$ |
(111,621 |
) |
|
$ |
89,397 |
|
(1) Includes external research and development and sales, general and administrative expenses associated with programs. (2) Includes salaries, benefits and other personnel related expenses, including stock based compensation expense, of relevant personnel. (3) Includes costs incurred for conducting non-program activities related to Company activities.
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