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  <xs:element id="ogn_RevenueInterestPurchaseAndSaleAgreementMember" abstract="true" name="RevenueInterestPurchaseAndSaleAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_OrganonFinance1LLCMember" abstract="true" name="OrganonFinance1LLCMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_DebtInstrumentRemainingPrincipalAmount" abstract="false" name="DebtInstrumentRemainingPrincipalAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ogn_RevenueInterestPurchaseAndSaleAgreementAndNovaQuestDebtMember" abstract="true" name="RevenueInterestPurchaseAndSaleAgreementAndNovaQuestDebtMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_DebtInstrumentDebtCovenantsDebtPrepaymentPeriodPriorToClosing" abstract="false" name="DebtInstrumentDebtCovenantsDebtPrepaymentPeriodPriorToClosing" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ogn_DebtInstrumentInterestPayments" abstract="false" name="DebtInstrumentInterestPayments" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ogn_DebtInstrumentAverageMaturity" abstract="false" name="DebtInstrumentAverageMaturity" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ogn_LongTermDebtMaturityAfterYearFour" abstract="false" name="LongTermDebtMaturityAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ogn_ContingentConsiderationLiabilityMember" abstract="true" name="ContingentConsiderationLiabilityMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_DisposalGroupContingentConsiderationAssetCurrent" abstract="false" name="DisposalGroupContingentConsiderationAssetCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ogn_CrossCurrencyInterestRateContractEuroDenominatedDebtInstrumentsMember" abstract="true" name="CrossCurrencyInterestRateContractEuroDenominatedDebtInstrumentsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_CrossCurrencyInterestRateContractU.S.DollarDenominatedDebtInstrumentsMember" abstract="true" name="CrossCurrencyInterestRateContractU.S.DollarDenominatedDebtInstrumentsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_EuroDenominatedTermLoanBFacilityMember" abstract="true" name="EuroDenominatedTermLoanBFacilityMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_A2034NotesMember" abstract="true" name="A2034NotesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_EuroDenominatedSubsidiariesMember" abstract="true" name="EuroDenominatedSubsidiariesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_ContingentConsiderationAcquiredMember" abstract="true" name="ContingentConsiderationAcquiredMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityFairValueAdjustment" abstract="false" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityFairValueAdjustment" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ogn_EuroDenominatedDebtInstrumentMember" abstract="true" name="EuroDenominatedDebtInstrumentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityAccretion" abstract="false" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityAccretion" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ogn_SamsungBioepisCoLtdMember" abstract="true" name="SamsungBioepisCoLtdMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_RenflexisAndBrenzysMember" abstract="true" name="RenflexisAndBrenzysMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_CollaborationArrangementAgreementPeriod" abstract="false" name="CollaborationArrangementAgreementPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ogn_CollaborativeArrangementAmendedFuturePayments" abstract="false" name="CollaborativeArrangementAmendedFuturePayments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="ogn_CollaborativeArrangementFuturePaymentTerm" abstract="false" name="CollaborativeArrangementFuturePaymentTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="ogn_CollaborationArrangementProfitSharingArrangementPercentage" abstract="false" name="CollaborationArrangementProfitSharingArrangementPercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ogn_ImplanonMember" abstract="true" name="ImplanonMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_NexplanonMember" abstract="true" name="NexplanonMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_FederalCourtMember" abstract="true" name="FederalCourtMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_NewJerseyStateCourtMember" abstract="true" name="NewJerseyStateCourtMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_PennsylvaniaStateCourtMember" abstract="true" name="PennsylvaniaStateCourtMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_CaliforniaStateCourtMember" abstract="true" name="CaliforniaStateCourtMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_FemurFractureMDLCourtMember" abstract="true" name="FemurFractureMDLCourtMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_NorthernDistrictOfOhioMember" abstract="true" name="NorthernDistrictOfOhioMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_FemurFractureLitigationMember" abstract="true" name="FemurFractureLitigationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_EncubeEthicalPrivateLimitedMember" abstract="true" name="EncubeEthicalPrivateLimitedMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_MylanPharmaceuticalsInc.MylanMember" abstract="true" name="MylanPharmaceuticalsInc.MylanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_NatcoPharmaLimitedMember" abstract="true" name="NatcoPharmaLimitedMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="ogn_MinimumPercentageOfAttorneysEligibleClientsToReleaseAnyLiabilityRelatedToTheirFiledClaims" abstract="false" name="MinimumPercentageOfAttorneysEligibleClientsToReleaseAnyLiabilityRelatedToTheirFiledClaims" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="ogn_LossContingencyUnfiledClaimsNumber" abstract="false" name="LossContingencyUnfiledClaimsNumber" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="ogn_LossContingencyMattersInvolvedNumber" abstract="false" name="LossContingencyMattersInvolvedNumber" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="ogn_LossContingencyNumberOfPlaintiffsToDeclineSettlementOffer" abstract="false" name="LossContingencyNumberOfPlaintiffsToDeclineSettlementOffer" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="ogn_NumberOfShareholderDerivativeLawsuitsFiled" abstract="false" name="NumberOfShareholderDerivativeLawsuitsFiled" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="ogn_LossContingencyPatentsUnderReview" abstract="false" name="LossContingencyPatentsUnderReview" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
</xs:schema>
