Trading Arrangements, by Individual Trading Arrangements, by Individual [Table] Trading Arrangement: Trading Arrangement [Axis] Maximum Maximum [Member] Statistical Measurement [Domain] Statistical Measurement [Domain] Title of 12(b) Security Title of 12(b) Security Document Fiscal Year Focus Document Fiscal Year Focus Adjustment to Compensation, Amount Adjustment to Compensation Amount Segment Reporting [Abstract] Restructuring Plan [Axis] Restructuring Plan [Axis] Common stock, $0.0001 par value, 200,000,000 shares authorized as of June 30, 2026 and December 31, 2025; 48,599,066 and 48,596,817 shares issued and outstanding as of June 30, 2026 and December 31, 2025, respectively Common Stock, Value, Issued Employee compensation and benefits Employee-related Liabilities, Current Schedule of Outstanding Term Loans Payable Schedule of Long-Term Debt Instruments [Table Text Block] Period for interest only payments (in months) Debt Instrument, Interest Only Payments, Period Debt Instrument, Interest Only Payments, Period Gains recognized related to the change in fair value of the derivative liability Change in fair value Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Period Increase (Decrease) Entity Ex Transition Period Entity Ex Transition Period Restatement Determination Date Restatement Determination Date Conversion price (in usd per share) Debt Instrument, Convertible, Conversion Price Amendment Flag Amendment Flag Gain on modification of lease liability Gain on modification of lease liability Gain (Loss) on Termination of Lease Current liabilities: Liabilities, Current [Abstract] Accounts payable, accrued expenses and other liabilities Increase (Decrease) in Accounts Payable and Other Operating Liabilities Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Fair value of derivative liability at issuance of term loan Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Issuances Leases [Abstract] Payments for other fees and expenses Payments For Other Fees And Expenses Payments For Other Fees And Expenses Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Entity Address, State or Province Entity Address, State or Province Granted (in shares) Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross PEO Total Compensation Amount PEO Total Compensation Amount Common stock par value (in usd per share) Common Stock, Par or Stated Value Per Share Weighted-average common shares outstanding, basic (in shares) Weighted Average Number of Shares Outstanding, Basic Non-cash interest expense Non-Cash Interest Expense Non-Cash Interest Expense Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Fair Value, by Balance Sheet Grouping [Table] Fair Value, by Balance Sheet Grouping [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Number of reportable segments Number of Reportable Segments Total current liabilities Liabilities, Current Period Three Debt Instrument, Covenant, Period Three [Member] Debt Instrument, Covenant, Period Three Subsequent Events Subsequent Events, Policy [Policy Text Block] Entity Address, City or Town Entity Address, City or Town Statement of Financial Position [Abstract] Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] Class of Stock [Axis] Class of Stock [Axis] Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount Proceeds from issuances under Employee Stock Purchase Plan Proceeds from Stock Plans Period Two Debt Instrument, Covenant, Period Two [Member] Debt Instrument, Covenant, Period Two Level 2 Fair Value, Inputs, Level 2 [Member] Other expense: Nonoperating Income (Expense) [Abstract] Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Amortization of debt discount and accretion of Final Fee (8.94%) Amortization of Debt Discount And Accretion Of Final Fee Amortization of Debt Discount And Accretion Of Final Fee Loan agreement, amount Line of Credit Facility, Maximum Borrowing Capacity Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Employee retention bonuses, benefits and related taxes Employee Retention Bonuses [Member] Employee Retention Bonuses Stock-based compensation Other Restructuring [Member] Allowable amount to invest in future offerings Debt Instrument, Covenant, Allowable Amount To Invest In Future Offerings Debt Instrument, Covenant, Allowable Amount To Invest In Future Offerings Schedule of Long-term Debt Instruments [Table] Schedule of Long-Term Debt Instruments [Table] Common stock to be issued upon exercise of the K2HV Loan Agreement conversion feature Loan Agreement [Member] Loan Agreement Recent Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Segment Reporting Segment Reporting [Table Text Block] Loss on sale and disposal of property and equipment, net Gain (Loss) on Disposition of Property Plant Equipment Use of Estimates Use of Estimates, Policy [Policy Text Block] Schedule of Accrued Expenses and Other Current Liabilities Schedule of Accrued Liabilities [Table Text Block] Schedule of Weighted-Average Significant Unobservable Inputs Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block] Net carrying amount of note payable Long-Term Debt Document Period End Date Document Period End Date Shares reserved for issuance under the 2021 Employee Stock Purchase Plan 2021 Stock Employee Stock Purchase Plan 2021 Stock Employee Stock Purchase Plan [Member] 2021 Stock Employee Stock Purchase Plan Changes in operating assets and liabilities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Net cash provided by investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Equity Awards Adjustments, Excluding Value Reported in Compensation Table Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member] Preferred stock outstanding (in shares) Preferred Stock, Shares Outstanding Manufacturing Operating Expense, Manufacturing, Adjustment Operating Expense, Manufacturing, Adjustment Common and Preferred Stock Equity [Text Block] Security Exchange Name Security Exchange Name Effective interest rate (percent) Debt Instrument, Interest Rate, Effective Percentage Granted (in usd per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Debt instrument, final fee amount Debt Instrument, External Leg Fees Debt Instrument, External Leg Fees Development and regulatory milestone payments Development and Regulatory Milestones Development and Regulatory Milestones Total liabilities Liabilities, Fair Value Disclosure Entity Shell Company Entity Shell Company Extinguishment of note payable Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings Common stock authorized to be issued (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Operating lease liability, current Operating Lease, Liability, Current Accrued interest Interest Payable, Current Stock option expiration period upon termination Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Upon Termination Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Upon Termination Net Income (Loss) Attributable to Common Stockholders per Share Earnings Per Share [Text Block] Name Outstanding Recovery, Individual Name Earnings Per Share [Abstract] Earnings Per Share [Abstract] Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] Document Fiscal Period Focus Document Fiscal Period Focus Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Total liabilities Liabilities Trading Symbol Trading Symbol Schedule of Interest Expense Interest Income and Interest Expense Disclosure [Table Text Block] Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Research and discovery Operating Expense, Research and Discovery, Adjustment Operating Expense, Research and Discovery, Adjustment Share-based compensation expense not yet recognized Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Company Selected Measure Name Company Selected Measure Name Sale of Stock [Domain] Sale of Stock [Domain] Market Offering Market Offering [Member] Market Offering Adjustment rate (percent) Debt Conversion, Converted Instrument, Rate Supplemental disclosure of non-cash investing and financing activities: Noncash Investing and Financing Items [Abstract] Note payable Long-Term Debt, Gross Operating activities: Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Compensation Amount Outstanding Recovery Compensation Amount Contract research Accrued Contract Research, Current Accrued Contract Research, Current Individual: Individual [Axis] Weighted-average common shares outstanding, diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted Entity Emerging Growth Company Entity Emerging Growth Company Equity Valuation Assumption Difference, Footnote Equity Valuation Assumption Difference, Footnote [Text Block] Underlying Security Market Price Change Underlying Security Market Price Change, Percent Dividends declared Dividends Payable Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Adjustment to right of use asset in exchange for reduction in lease liability Adjustment To Right-of-Use Asset In Exchange For Reduction In Lease Liability Adjustment To Right-of-Use Asset In Exchange For Reduction In Lease Liability Measurement input Embedded Derivative Liability, Measurement Input Lease termination Operating Lease, Payments Award Timing Predetermined Award Timing Predetermined [Flag] Adjustment To PEO Compensation, Footnote Adjustment To PEO Compensation, Footnote [Text Block] Level 1 Fair Value, Inputs, Level 1 [Member] Organization, Consolidation and Presentation of Financial Statements [Abstract] Area of building space Area of Real Estate Property All Executive Categories All Executive Categories [Member] Operating lease liability Increase (Decrease) in Operating Lease Liability Pension Adjustments Service Cost Pension Adjustments Service Cost [Member] Preferred stock par value (in usd per share) Preferred Stock, Par or Stated Value Per Share Depreciation expense Depreciation Plan Name [Domain] Plan Name [Domain] Antidilutive Securities [Axis] Antidilutive Securities [Axis] Outstanding at beginning of period (in usd per share) Outstanding at end of period (in usd per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Reconciliation of cash, cash equivalents and restricted cash and cash equivalents to the condensed consolidated balance sheets Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation [Abstract] Operating lease right of use asset Operating Lease, Right-of-Use Asset Fair Value Disclosures [Abstract] Debt Disclosure [Abstract] Debt Instrument, Name [Domain] Debt Instrument, Name [Domain] Sales commissions, percentage Sales Commissions, Percentage Sales Commissions, Percentage Segment Information Segment Reporting [Text Block] Minimum Minimum [Member] Expiration Date Trading Arrangement Expiration Date Income Statement Location [Axis] Location, Statement of Income, Balance [Axis] Non-Rule 10b5-1 Arrangement Adopted Non-Rule 10b5-1 Arrangement Adopted [Flag] Money market funds Cash and Cash Equivalents, Fair Value Disclosure Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted-Average Remaining Contractual Term Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member] Expected contingent payment Collaborative Arrangement, Expected Contingent Consideration Collaborative Arrangement, Expected Contingent Consideration Repayments of notes payable Repayments of Notes Payable Exercisable at end of period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Issuance costs Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs Aggregate Pension Adjustments Service Cost Aggregate Pension Adjustments Service Cost [Member] Proceeds from at the market offering of common stock, net of issuance costs Proceeds from Issuance of Common Stock Common stock authorized (in shares) Common Stock, Shares Authorized Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Antidilutive Security, Excluded EPS Calculation [Table] Exercise Price Award Exercise Price Restructuring Cost [Table] Restructuring Cost [Table] Investing activities: Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] 2026 Restructuring Plan 2026 Restructuring Plan [Member] 2026 Restructuring Plan Segment Reporting [Line Items] Segment Reporting [Line Items] Document Quarterly Report Document Quarterly Report Debt Instrument, Covenant, Period [Axis] Debt Instrument, Covenant, Period [Axis] Debt Instrument, Covenant, Period Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member] Segments [Domain] Segments [Domain] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Period Four Debt Instrument, Covenant, Period Four [Member] Debt Instrument, Covenant, Period Four Term Loan Debt Disclosure [Text Block] Unamortized debt discount and issuance costs Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net Amount of net cash proceeds from certain financing activities Debt Instrument, Covenant, Achievement of Milestones and Receipt Of Proceeds From Financing Activities Debt Instrument, Covenant, Achievement of Milestones and Receipt Of Proceeds From Financing Activities Schedule of Restructuring and Related Costs Restructuring and Related Costs [Table Text Block] Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] Balance at beginning of period Balance at beginning of period Restructuring Reserve Equity Component [Domain] Equity Component [Domain] PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount Measurement Input Type [Domain] Measurement Input Type [Domain] Business Combination, Asset Acquisition, Transaction between Entities under Common Control, and Joint Venture Formation [Abstract] Adoption Date Trading Arrangement Adoption Date Total stockholders’ equity Stockholders' equity, beginning balance Stockholders' equity, ending balance Equity, Attributable to Parent Total other expense Nonoperating Income (Expense) Loss on extinguishment of debt Deferred Debt Issuance Cost, Writeoff Restructuring Type [Axis] Restructuring Type [Axis] Stock-based compensation expense APIC, Share-Based Payment Arrangement, Option, Increase for Cost Recognition Assets Assets [Abstract] Title Trading Arrangement, Individual Title Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Facility fee Debt Instrument, Fee Amount Accounting Policies [Abstract] Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Risk-free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Operating lease, liability Operating Lease, Liability Insider Trading Policies and Procedures [Line Items] Outstanding at beginning of period (in shares) Outstanding at end of period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current General and administrative support Selling, General and Administrative Expense Type of Restructuring [Domain] Type of Restructuring [Domain] Maximum number of shares to be added annually, as a percentage of outstanding shares (percent) Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum Amortization of employee retention bonuses paid in the prior period Restructuring Reserve, Amortization Of Employee Retention Bonuses Paid In The Prior Period Restructuring Reserve, Amortization Of Employee Retention Bonuses Paid In The Prior Period Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Dividend yield (continuous) Measurement Input, Expected Dividend Rate [Member] Antidilutive securities excluded from computation of earnings per share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Schedule of Antidilutive Securities Excluded from Computation of Loss per Share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Entity Central Index Key Entity Central Index Key Note payable, net of discount and issuance costs Notes Payable, Current All Adjustments to Compensation All Adjustments to Compensation [Member] Accretion of debt discount (percent) Amortization of Debt Discount And Accretion Of Final Fee, Percentage Amortization of Debt Discount And Accretion Of Final Fee, Percentage Equity [Abstract] Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Net cash used in operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Debt Instrument, Covenant, Period [Domain] Debt Instrument, Covenant, Period [Domain] Debt Instrument, Covenant, Period Income Statement [Abstract] Shares purchased by employees (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Document Transition Report Document Transition Report Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Notice period to terminate lease Lessee, Operating Leases, Notice Period To Terminate Lessee, Operating Leases, Notice Period To Terminate Restructuring Plan [Domain] Restructuring Plan [Domain] Coupon rate (percent) Interest Expense, Coupon Rate, Percentage Interest Expense, Coupon Rate, Percentage Volatility Measurement Input, Volatility [Member] Measurement Input, Volatility Operating expenses: Operating Expenses [Abstract] Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] Schedule of Weighted -average Valuation Assumptions Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Number of Options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Floating rate spread in effect (greater than) (percent) Debt Instrument, Basis Spread on Variable Rate City Area Code City Area Code Common stock to be issued upon exercise of the K2HV Loan Agreement conversion feature Restricted Stock [Member] All Individuals All Individuals [Member] Common stock to be issued upon exercise of the K2HV Loan Agreement conversion feature Convertible Debt Securities [Member] Non-cash lease expense Operating Lease, Right-of-Use Asset, Periodic Reduction Collaborative Arrangement Collaborative Arrangement [Member] Name Forgone Recovery, Individual Name Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward] Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward] Share-based compensation not yet recognized, recognition period Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Statement [Line Items] Statement [Line Items] Total assets Assets Minimum amount of offering of common stock Debt Instrument, Covenant, Minimum Amount Of Single Offering of Common Stock Debt Instrument, Covenant, Minimum Amount Of Single Offering of Common Stock Common stock to be issued under the 2021 ESPP Common Stock Issued Under The 2021 ESPP [Member] Common Stock Issued Under The 2021 ESPP Preferred stock issued (in shares) Preferred Stock, Shares Issued Common stock available for issuance (in shares) Common Stock, Capital Shares Reserved for Future Issuance Contingent consideration Collaborative Arrangement, Contingent Consideration Collaborative Arrangement, Contingent Consideration Weighted-average grant date fair value of awards (in usd per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Interest expense Interest Expense, Nonoperating Schedule of Stock-based Compensation Expense Recognized Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] 2017 Stock Incentive Plan 2017 Stock Incentive Plan [Member] 2017 Stock Incentive Plan Stock-based Compensation Share-Based Payment Arrangement [Text Block] Issuance of common stock from at the market offering, net of issuance costs (in shares) Stock Issued During Period, Shares, New Issues PEO PEO [Member] Debt instrument variable rate floor (percent) Debt Instrument, Variable Rate Floor Debt Instrument, Variable Rate Floor Cash and Cash Equivalents [Domain] Cash and Cash Equivalents [Domain] Reportable Segment Reportable Segment [Member] Reportable Segment ATM Offering - Baby Shelf Limitation ATM Offering - Baby Shelf Limitation [Member] ATM Offering - Baby Shelf Limitation Total stock-based compensation Share-Based Payment Arrangement, Expense Maximum number of shares to be added annually, as a percentage of outstanding shares (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Stock option exercises (in shares) Exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Fair Value Measurement Inputs and Valuation Techniques [Line Items] Fair Value Measurement Inputs and Valuation Techniques [Line Items] Payables and Accruals [Abstract] Accumulated Deficit Retained Earnings [Member] Operating lease liability, net of current portion Operating Lease, Liability, Noncurrent Total operating expenses Operating Expenses Money market funds Money Market Funds [Member] Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Cancelled (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Common stock outstanding (in shares) Stockholders' equity, beginning balance (in shares) Stockholders' equity, ending balance (in shares) Common Stock, Shares, Outstanding Award Timing Disclosures [Line Items] Payment of debt issuance costs Payments of Debt Issuance Costs Net income (loss) per common share, diluted (in usd per share) Earnings Per Share, Diluted Entity Current Reporting Status Entity Current Reporting Status Net cash (used in) provided by financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Total Shareholder Return Amount Total Shareholder Return Amount Prepaid expenses and other assets Increase (Decrease) in Prepaid Expense and Other Assets Term Loans Term Loans [Member] Term Loans Research and development Research and Development Expense Stock price (in usd per share) Measurement Input, Share Price [Member] Adjustments to reconcile net loss to net cash used in operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Accrued Expenses and Other Current Liabilities Accrued Expenses and Other Current Liabilities Disclosure [Text Block] Accrued Expenses and Other Current Liabilities Share-Based Payment Arrangement [Abstract] Financing activities: Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Property and equipment, net Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization Schedule of Common Stock Reserved for Issuance Schedule of Stockholders Equity [Table Text Block] Contract termination costs Contract Termination [Member] Assets: Financial Instruments, Financial Assets, Balance Sheet Groupings [Abstract] Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Underlying Securities Award Underlying Securities Amount Issuance of common stock from at the market offering, net of issuance costs Stock Issued During Period, Value, New Issues Cancelled (in usd per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Segment Reporting [Table] Segment Reporting [Table] Sale of Stock [Axis] Sale of Stock [Axis] Weighted-Average Remaining
Contractual Life
(in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] All Trading Arrangements All Trading Arrangements [Member] Balance at beginning of period Balance at end of period Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value Schedule of Assets Measured at Fair Value on a Recurring Basis Fair Value Measurements, Recurring and Nonrecurring [Table Text Block] Change in fair value of derivative liability Derivative, Gain (Loss) on Derivative, Net Other Performance Measure, Amount Other Performance Measure, Amount Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Operating income (loss) Operating Income (Loss) Current Fiscal Year End Date Current Fiscal Year End Date Proceeds from drawdown of term loans Proceeds from Issuance of Debt Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Total Estimated Costs Restructuring and Related Cost, Expected Cost Restructuring Reserve [Roll Forward] Restructuring Reserve [Roll Forward] Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Shares reserved for exercises of outstanding stock options Equity Option [Member] Entity File Number Entity File Number Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Sales-based milestone payments Sales-Based Milestones Sales-Based Milestones Schedule of Stock Option Activity Share-Based Payment Arrangement, Option, Activity [Table Text Block] Weighted-Average Exercise Price per Share Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Total restructuring costs Restructuring costs recognized during the period Restructuring Costs Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Common stock issued (in shares) Common Stock, Shares, Issued Measure: Measure [Axis] Clinical development Operating Expense, Clinical Development, Adjustment Operating Expense, Clinical Development, Adjustment One-time charge related to modification Share-Based Payment Arrangement, Plan Modification, Incremental Cost Equity Components [Axis] Equity Components [Axis] Class of Stock [Line Items] Class of Stock [Line Items] 2021 Stock Incentive Plan 2021 Stock Incentive Plan [Member] 2021 Stock Incentive Plan Restructuring costs Restructuring Reserve, Current Entity Interactive Data Current Entity Interactive Data Current Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Entity Small Business Entity Small Business Debt discount Debt Instrument, Unamortized Discount Termination Date Trading Arrangement Termination Date Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] Employee retention bonuses paid in advance Restructuring Reserve, Employee Retention Bonuses Paid In Advance Restructuring Reserve, Employee Retention Bonuses Paid In Advance MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Stock option expiration period Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Other assets Other Assets, Noncurrent Document Type Document Type Loss on extinguishment of note payable Loss on extinguishment of note payable Gain (Loss) on Extinguishment of Debt Accrued expenses and other current liabilities Total accrued expenses and other current liabilities Accrued Liabilities, Current Fair Value as of Grant Date Award Grant Date Fair Value Exercisable, Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Purchase period Employee Stock Ownership Plan, Purchase Period Employee Stock Ownership Plan, Purchase Period Arrangement Duration Trading Arrangement Duration Statement of Stockholders' Equity [Abstract] Local Phone Number Local Phone Number Entity Address, Postal Zip Code Entity Address, Postal Zip Code Entity Registrant Name Entity Registrant Name Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Period One Debt Instrument, Covenant, Period One [Member] Debt Instrument, Covenant, Period One Commitments and contingencies Commitments and Contingencies Collaboration revenue Revenues Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Executive Category: Executive Category [Axis] Repayment of note payable and extinguishment costs Repayment Of Note Payable And Extinguishment Costs Repayment Of Note Payable And Extinguishment Costs Liabilities and stockholders’ equity Liabilities and Equity [Abstract] Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted-Average Remaining Contractual Term Award Type [Domain] Award Type [Domain] Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount Financial Instruments and Fair Value Measurements Fair Value Disclosures [Text Block] Level 3 Fair Value, Inputs, Level 3 [Member] Supplemental disclosure of cash flow information: Supplemental Cash Flow Information [Abstract] Expected term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Collaboration revenue Revenue from Collaborative Arrangement, Excluding Revenue from Contract with Customer PEO Name PEO Name Liabilities: Financial Instruments, Financial Liabilities, Balance Sheet Groupings [Abstract] Other segment expenses Segment Reporting, Other Segment Item, Amount Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Entity Tax Identification Number Entity Tax Identification Number Total interest expense on effective rate (19.24%) Interest Expense, Debt Cash payments made during the period Payments for Restructuring Exercised (in usd per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Cash, cash equivalents and restricted cash and cash equivalents—beginning of period Cash, cash equivalents and restricted cash and cash equivalents—end of period Total cash, cash equivalents and restricted cash and cash equivalents Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Professional fees Accrued Professional Fees, Current Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Other Other Accrued Liabilities, Current Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Non-NEOs Non-NEOs [Member] Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Nature of Business Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Debt Instrument [Axis] Debt Instrument [Axis] Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense Lease Termination Lessee, Operating Leases [Text Block] Long-term Debt, Type [Domain] Long-Term Debt, Type [Domain] Net income (loss) per common share, basic (in usd per share) Earnings Per Share, Basic Measurement Input Type [Axis] Measurement Input Type [Axis] Risk-free rate (continuous) Measurement Input, Risk Free Interest Rate [Member] Total current assets Assets, Current Statistical Measurement [Axis] Statistical Measurement [Axis] Insider Trading Arrangements [Line Items] Award Type [Axis] Award Type [Axis] ATM Offering ATM Offering [Member] ATM Offering Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Accumulated deficit Retained Earnings (Accumulated Deficit) Restructuring and Related Activities [Abstract] Restricted cash and cash equivalents Restricted Cash, Noncurrent Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Capacity available to draw on the term loans Debt Instrument, Unused Borrowing Capacity, Amount Common Stock Common Stock [Member] Expected volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Employee severance, benefits and related taxes Employee Severance [Member] Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Cover [Abstract] Expected annual dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Reduction in workforce (percent) Restructuring and Related Cost, Number of Positions Eliminated, Period Percent Offering period Employee Stock Ownership Plan, Offering Period Employee Stock Ownership Plan, Offering Period Interest expense based on coupon interest rate (10.3%) of outstanding term loans Interest Expense, Debt, Excluding Amortization Fair Value Measurement Inputs and Valuation Techniques [Table] Fair Value Measurement Inputs and Valuation Techniques [Table] Term loan Loans Payable [Member] Equity Awards Adjustments Equity Awards Adjustments [Member] Collaboration Revenue Collaborative Arrangement Disclosure [Text Block] Total liabilities and stockholders’ equity Liabilities and Equity Derivative liability Derivative Liability, Noncurrent Shares reserved for issuance under the 2021 Stock Incentive Plan Outstanding stock options Share-Based Payment Arrangement, Option [Member] Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] Segments [Axis] Segments [Axis] Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Plan Name [Axis] Plan Name [Axis] Tabular List, Table Tabular List [Table Text Block] Restricted cash and cash equivalents Restricted Cash and Cash Equivalent, Noncurrent Additional paid-in capital Additional Paid in Capital Other income, net Other Nonoperating Income (Expense) Name Awards Close in Time to MNPI Disclosures, Individual Name ESPP purchase price, percent Employee Stock Ownership Plan, Purchase Price, Percent Employee Stock Ownership Plan, Purchase Price, Percent Stockholders’ equity: Equity, Including Portion Attributable to Noncontrolling Interest [Abstract] Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] Outstanding, Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value General and administrative General and Administrative Expense Price per share (in usd per share) Sale of Stock, Price Per Share Preferred stock authorized (in shares) Preferred Stock, Shares Authorized Preferred stock, $0.0001 par value, 5,000,000 shares authorized as of June 30, 2026 and December 31, 2025; no shares issued or outstanding as of June 30, 2026 and December 31, 2025 Preferred Stock, Value, Issued Adjustment to Compensation: Adjustment to Compensation [Axis] Class of Stock [Domain] Class of Stock [Domain] Restructuring Cost and Reserve [Line Items] Restructuring Cost and Reserve [Line Items] Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Cash paid for interest Interest Paid, Excluding Capitalized Interest, Operating Activity Statement of Cash Flows [Abstract] Strategic Review and Liquidity Restructuring Restructuring and Related Activities Disclosure [Text Block] Issuance costs in accounts payable and accrued expenses Stock Issuance Costs Incurred But Not Yet Paid Stock Issuance Costs Incurred But Not Yet Paid Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Total assets Assets, Fair Value Disclosure Non-compete covenant period Collaborative Arrangement, Non-Compete Covenant Period Collaborative Arrangement, Non-Compete Covenant Period Additional interest rate (percent) Debt Instrument, Additional Interest Rate Debt Instrument, Additional Interest Rate Name Measure Name Non-cash charges recognized during the period Restructuring Reserve, Settled without Cash Accounts payable Accounts Payable, Current Pay vs Performance Disclosure [Line Items] Fair Value Hierarchy and NAV [Domain] Fair Value Hierarchy and NAV [Domain] Debt Instrument [Line Items] Debt Instrument [Line Items] Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Additional Paid-in Capital Additional Paid-in Capital [Member] Entity Filer Category Entity Filer Category Shares reserved for issuance as part of the K2HV Loan Agreement conversion feature K2HV Conversion Feature [Member] K2HV Conversion Feature Final fee, percentage Debt Instrument, Final Fee, Percentage Debt Instrument, Final Fee, Percentage Name Trading Arrangement, Individual Name Cash and cash equivalents Cash and cash equivalents Cash and Cash Equivalent Expected term (in years) Measurement Input, Expected Term [Member] Manufacturing Accrued Manufacturing, Current Accrued Manufacturing, Current Company Selected Measure Amount Company Selected Measure Amount Common stock, amount authorized Common Stock, Amount Authorized Common Stock, Amount Authorized Entity Address, Address Line Two Entity Address, Address Line Two Schedule of Stock by Class [Table] Stock, Class of Stock [Table] Current assets: Assets, Current [Abstract] Derivative liability Derivative Liability Non-PEO NEO Non-PEO NEO [Member] Entity Address, Address Line One Entity Address, Address Line One Award Timing Method Award Timing Method [Text Block] Consolidation Consolidation, Policy [Policy Text Block] Net decrease in cash, cash equivalents and restricted cash and cash equivalents Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Net income (loss) Net income (loss) Net loss Net Income (Loss) Attributable to Parent Long-term Debt, Type [Axis] Long-Term Debt, Type [Axis] Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Proceeds from sale of property and equipment Proceeds from Sale of Property, Plant, and Equipment Statement [Table] Statement [Table] Restatement Determination Date: Restatement Determination Date [Axis] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Interest income Investment Income, Interest Conversion of outstanding principal Debt Conversion, Converted Instrument, Amount Exercisable at end of period (in usd per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Cash and Cash Equivalents [Axis] Cash and Cash Equivalents [Axis] Revenue: Revenues [Abstract] Summary of Significant Accounting Policies Basis of Presentation and Significant Accounting Policies [Text Block] Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block]