v3.26.1
Segment Reporting and Disaggregation of Relevant Expense Captions - Segment Reporting Information, by Segment (Details) - USD ($)
$ in Millions
 3 Months Ended 6 Months Ended
Jun. 30, 2026
Jun. 30, 2025
Jun. 30, 2026
Jun. 30, 2025
Segment Reporting [Line Items]        
Total revenues $ 959.0 $ 687.5 $ 1,773.5 $ 1,260.1
Less:        
Cost of revenues, excluding amortization of acquired intangible assets 23.2 10.3 36.9 18.5
Total research and development 326.7 244.3 622.9 507.5
Acquired in-process research and development 1.5 0.0 22.7 0.1
Selling, general, and administrative 439.7 286.3 758.2 562.8
Amortization of acquired intangible assets 16.4 1.0 16.5 2.0
Gain on sale of business, net of transaction costs 0.0 0.0 (28.6) 0.0
Interest expense 2.9 0.0 2.9 0.0
Unrealized (gain) loss on equity investments (1.2) 6.7 (26.5) 37.3
Investment income and other, net (12.4) (20.6) (40.5) (42.3)
Provision for income taxes 17.8 52.0 66.7 58.8
Net income 144.4 107.5 342.3 115.4
Reportable Segment        
Segment Reporting [Line Items]        
Total revenues 959.0 687.5 1,773.5 1,260.1
Less:        
Cost of revenues, excluding amortization of acquired intangible assets 23.2 10.3 36.9 18.5
Total research and development 326.7 244.3 622.9 507.5
Acquired in-process research and development 1.5 0.0 22.7 0.1
Selling, general, and administrative 439.7 286.3 758.2 562.8
Amortization of acquired intangible assets 16.4 1.0 16.5 2.0
Gain on sale of business, net of transaction costs 0.0 0.0 (28.6) 0.0
Interest expense 2.9 0.0 2.9 0.0
Unrealized (gain) loss on equity investments (1.2) 6.7 (26.5) 37.3
Investment income and other, net (12.4) (20.6) (40.5) (42.3)
Provision for income taxes 17.8 52.0 66.7 58.8
Net income 144.4 107.5 342.3 115.4
Reportable Segment | INGREZZA net product sales        
Segment Reporting [Line Items]        
Total revenues 716.5 624.4 1,373.3 1,169.6
Reportable Segment | CRENESSITY net product sales        
Segment Reporting [Line Items]        
Total revenues 183.5 53.2 336.8 67.7
Reportable Segment | VYKAT XR net product sales        
Segment Reporting [Line Items]        
Total revenues 54.3 0.0 54.3 0.0
Reportable Segment | Other revenues        
Segment Reporting [Line Items]        
Total revenues 4.7 9.9 9.1 22.8
Reportable Segment | External research and development        
Less:        
Total research and development 168.5 120.6 316.5 228.5
Reportable Segment | Payroll and benefits        
Less:        
Total research and development 115.4 72.2 199.9 147.2
Reportable Segment | Milestones        
Less:        
Total research and development 0.3 15.1 22.9 60.5
Reportable Segment | Other research and development        
Less:        
Total research and development $ 42.5 $ 36.4 $ 83.6 $ 71.3