Other Balance Sheet Components (Tables)
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6 Months Ended |
Jun. 30, 2026 |
| Organization, Consolidation and Presentation of Financial Statements [Abstract] |
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| Schedule of Accounts, Notes, Loans and Financing Receivable |
Accounts receivable, net, as of June 30, 2026 and December 31, 2025 consisted of the following (in millions): | | | | | | | | | | | | | | | | | June 30, | | December 31, | | | 2026 | | 2025 | | Accounts receivable | | $ | 120 | | | $ | 368 | | | | | | | Less: Allowance for doubtful accounts | | (6) | | | (3) | | Less: Wholesalers chargebacks, discounts and fees | | (97) | | | (181) | | | Accounts receivable, net | | $ | 17 | | | $ | 184 | |
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| Schedule of Prepaid Expenses and Other Current Assets |
Prepaid expenses and other current assets, as of June 30, 2026 and December 31, 2025 consisted of the following (in millions): | | | | | | | | | | | | | | | | | | | June 30, | | December 31, | | | | | 2026 | | 2025 | | | | Prepaid services | | $ | 146 | | | $ | 169 | | | | Down payments and prepayments related to manufacturing and materials | | 70 | | | 61 | | | | | Interest receivable | | 40 | | | 42 | | | | | | | | | | | Prepaid income tax and income tax receivable | | 36 | | | 41 | | | | Research and development funding receivable (Note 5) | | 31 | | | — | | | | | | | | | | | | Value added tax receivable | | 15 | | | 37 | | | | | | | | | | | Collaboration receivable (Note 5) | | — | | | 13 | | | | | Other current assets | | 42 | | | 45 | | | | | | | | | | | | | | | | | | | Prepaid expenses and other current assets | | $ | 380 | | | $ | 408 | | | | | | | | | | |
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| Schedule of Other Non-Current Assets |
Other non-current assets, as of June 30, 2026 and December 31, 2025 consisted of the following (in millions): | | | | | | | | | | | | | | | | | June 30, | | December 31, | | | 2026 | | 2025 | Income tax receivable, non-current | | $ | 161 | | | $ | 161 | | Finite-lived intangible assets, net(2) | | 109 | | | 45 | | Down payments and prepayments, non-current | | 90 | | | 100 | | Deferred tax assets | | 82 | | | 81 | | Inventory, non-current(1) | | 81 | | | 114 | | Goodwill | | 52 | | | 52 | | | | | | | | | | | | | Other | | 43 | | | 52 | | | Other non-current assets | | $ | 618 | | | $ | 605 | |
_______ (1)Consisted of raw materials with an anticipated consumption beyond one year. (2)Includes a $66 million intangible asset related to a license recognized in connection with the settlement agreement with Arbutus and Genevant. See Note 12 for additional details.
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| Schedule of Accrued Liabilities |
Accrued liabilities, as of June 30, 2026 and December 31, 2025 consisted of the following (in millions): | | | | | | | | | | | | | | | | | June 30, | | December 31, | | | 2026 | | 2025 | Royalties(1) | | $ | 954 | | | $ | 31 | | Provisions related to product sales (Note 3) | | 421 | | | 509 | | | Compensation-related | | 192 | | | 420 | | | Manufacturing | | 86 | | | 140 | | | Development operations | | 78 | | | 106 | | | Other external goods and services | | 58 | | | 57 | | | Raw materials | | 44 | | | 30 | | | Clinical trials | | 38 | | | 20 | | | Property, plant and equipment | | 18 | | | 45 | | Commercial | | 18 | | | 23 | | Loss on future firm purchase commitments(2) | | 2 | | | 5 | | | | | | | | Accrued liabilities | | $ | 1,909 | | | $ | 1,386 | |
______ (1) Includes $950 million related to the litigation settlement with Arbutus and Genevant (Note 12). (2) Related to losses that are expected to arise from firm, non-cancellable, commitments for future raw material purchases (Note 7).
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| Schedule of Other Current Liabilities |
Other current liabilities, as of June 30, 2026 and December 31, 2025 consisted of the following (in millions): | | | | | | | | | | | | | | | | | | | June 30, | | December 31, | | | | | 2026 | | 2025 | | | Estimated reimbursements to wholesalers and distributors | | $ | 58 | | | $ | 84 | | | | Lease liabilities - financing (Note 10) | | 31 | | | 25 | | | | Lease liabilities - operating (Note 10) | | 21 | | | 17 | | | | Collaboration liabilities (Note 5) | | 15 | | | — | | | | Research and development funding liability (Note 5) | | 14 | | | 43 | | | | | | | | | | | | Other | | 24 | | | 16 | | | | | Other current liabilities | | $ | 163 | | | $ | 185 | | | |
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| Schedule of Other Noncurrent Liabilities |
Other non-current liabilities, as of June 30, 2026 and December 31, 2025 consisted of the following (in millions): | | | | | | | | | | | | | | | | | June 30, | | December 31, | | | 2026 | | 2025 | Tax liabilities | | $ | 255 | | | $ | 249 | | Other | | 29 | | | 36 | | Other non-current liabilities | | $ | 284 | | | $ | 285 | |
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| Schedule of Deferred Revenue |
The following table summarizes the activities related to product sales provision recorded as accrued liabilities for the six months ended June 30, 2026 (in millions): | | | | | | | | | | | Returns and other fees | | Balance at December 31, 2025 | | $ | (509) | | Provision related to sales made in current period | | (23) | | Provision related to sales made in prior periods | | 36 | | | Payments and returns related to sales made in current period | | 1 | | Payments and returns related to sales made in prior year | | 74 | | | Balance at June 30, 2026 | | $ | (421) | |
The following table summarizes the activities in deferred revenue for the six months ended June 30, 2026 (in millions): | | | | | | | | | | | | | | | | | | | | | | | | | | | | | December 31, 2025 | | Additions | | Deductions | | June 30, 2026 | Net product sales | | $ | 107 | | | $ | 171 | | | $ | (13) | | | $ | 265 | | | Other revenue | | 145 | | | 117 | | | (85) | | | 177 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Total deferred revenue | | $ | 252 | | | $ | 288 | | | $ | (98) | | | $ | 442 | |
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