Property, plant and equipment, net, as of June 30, 2026 and December 31, 2025 consisted of the following (in millions): | | | | | | | | | | | | | | | | | June 30, | | December 31, | | | 2026 | | 2025 | Land and land improvements | | $ | 77 | | | $ | 78 | | Building and building improvements | | 1,216 | | | 1,183 | | | Manufacturing and laboratory equipment | | 550 | | | 542 | | Leasehold improvements | | 409 | | | 403 | | | Furniture, fixtures and other | | 40 | | | 39 | | Computer equipment and software | | 205 | | | 196 | | | | | | | Construction in progress | | 279 | | | 298 | | Right-of-use assets, financing (Note 10) | | 132 | | | 132 | | | Total | | 2,908 | | | 2,871 | | Less: Accumulated depreciation | | (849) | | | (737) | | | Property, plant and equipment, net | | $ | 2,059 | | | $ | 2,134 | | | | | | |
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