v3.26.1
Property, Plant and Equipment, Net
 6 Months Ended
Jun. 30, 2026
Property, Plant, and Equipment [Abstract]  
Property, Plant and Equipment, Net
8. Property, Plant and Equipment, Net

Property, plant and equipment, net, as of June 30, 2026 and December 31, 2025 consisted of the following (in millions):
June 30,December 31,
20262025
Land and land improvements
$77 $78 
Building and building improvements
1,216 1,183 
Manufacturing and laboratory equipment550 542 
Leasehold improvements
409 403 
Furniture, fixtures and other40 39 
Computer equipment and software
205 196 
Construction in progress
279 298 
Right-of-use assets, financing (Note 10)
132 132 
Total2,908 2,871 
Less: Accumulated depreciation
(849)(737)
Property, plant and equipment, net$2,059 $2,134 

Depreciation and amortization expense related to property, plant and equipment for the three and six months ended June 30, 2026 was $56 million and $112 million, respectively. Depreciation and amortization expense related to property, plant and equipment for the three and six months ended June 30, 2025 was $56 million and $94 million, respectively.