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Operating Expenses [Abstract] Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] Schedule of Fair Value of Stock Options was Estimated using Weighted-average Assumptions Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Options Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] City Area Code City Area Code Accumulated Other Comprehensive Income (Loss) AOCI Attributable to Parent [Member] All Individuals All Individuals [Member] Noncash operating lease expense Operating Lease, Right-of-Use Asset, Periodic Reduction Name Forgone Recovery, Individual Name Weighted-average period (in years) Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Amortized Cost Cash, Cash Equivalents And Available-For-Sale Debt Securities, Amortized Cost Cash, Cash 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Unrealized Gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Shares purchased through employee stock purchase plan Stock Issued During Period, Value, Employee Stock Purchase Plan PEO PEO [Member] Beginning balance (in shares) Ending balance (in shares) Shares, Outstanding Cash and Cash Equivalents [Domain] Cash and Cash Equivalents [Domain] Options expired (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Share-based payment arrangement, expense Share-Based Payment Arrangement, Expense Marketable securities Marketable Securities, Current Cash Equivalents Cash Equivalents [Member] Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Debt securities, available-for-sale, unrealized loss position, number of positions Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions Exercise of stock options (in shares) Options exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Amortized Cost Cash Equivalents, at Carrying Value Accumulated Deficit Retained Earnings [Member] Operating lease liabilities, net of current portion Operating lease liabilities, net of current portion Operating Lease, Liability, Noncurrent Total operating expenses Operating Expenses Money Market Funds Money Market Funds [Member] Fair Value Measurements Fair Value Measurement, Policy [Policy Text Block] Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Options cancelled and forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Unrealized gain (loss) on marketable securities Unrealized (loss) gain on marketable securities OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Common stock, shares, outstanding (in shares) Common Stock, Shares, Outstanding Award Timing Disclosures [Line Items] Corporate debt securities Corporate Debt Securities [Member] Net loss per share, diluted (in dollars per share) Earnings Per Share, Diluted Entity Current Reporting Status Entity Current Reporting Status Unrealized Gain Cash Equivalents, Accumulated Gross Unrealized Gain, Before Tax Cash Equivalents, Accumulated Gross Unrealized Gain, Before Tax Net cash provided by financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Interim Period, Costs Not Allocable [Domain] Interim Period, Costs Not Allocable [Domain] Total Shareholder Return Amount Total Shareholder Return Amount Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets Follow-on Offering Follow-on Offering [Member] Follow-on Offering Research and development Research and Development Expense Lease Contractual Term [Domain] Lease Contractual Term [Domain] J&J License Agreement J&J License Agreement [Member] Represents the J&J License Agreement. Financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Property and equipment, net Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization Losses Cash And Cash Equivalents And Debt Securities, Available-For-Sale, Accumulated Gross Unrealized Loss, Before Tax Cash And Cash Equivalents And Debt Securities, Available-For-Sale, Accumulated Gross Unrealized Loss, Before Tax Maturity in Years Debt Securities, Available-for-Sale, Term Financial Instruments [Domain] Financial Instruments [Domain] Exercise of stock options Stock Issued During Period, Value, Stock Options Exercised Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Underlying Securities Award Underlying Securities Amount Common stock warrant Common Stock Warrant [Member] Represents common stock warrant. Shares available for issuance under the 2026 Inducement Plan 2026 Inducement Plan [Member] 2026 Inducement Plan Options cancelled and forfeited (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Segment Reporting [Table] Segment Reporting [Table] Sale of Stock [Axis] Sale of Stock [Axis] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Schedule of Lease, Cost Lease, Cost [Table Text Block] Schedule of Amortized Cost and Fair Value of the Company’s Cash Equivalents and Marketable Securities by Major Investment Category Schedule of Available-for-Sale Securities Reconciliation [Table Text Block] Commitments and Contingencies Disclosure [Abstract] All Trading Arrangements All Trading Arrangements [Member] Other Performance Measure, Amount Other Performance Measure, Amount Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Loss from operations Loss from operations Operating Income (Loss) Current Fiscal Year End Date Current Fiscal Year End Date Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Yankee debt Debt Security, Government, Non-US [Member] Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Entity File Number Entity File Number Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Schedule of Stock Option Activity Share-Based Payment Arrangement, Option, Activity [Table Text Block] Weighted- Average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Common stock, shares, issued (in shares) Common Stock, Shares, Issued Measure: Measure [Axis] Entity Information [Line Items] Entity Information [Line Items] Equity Components [Axis] Equity Components [Axis] Product and Service [Domain] Product and Service [Domain] Class of Stock [Line Items] Class of Stock [Line Items] PIPE-791 PIPE-791 [Member] In relation to the product PIPE-791. Class A Common Class A [Member] Upfront payment received Upfront Payment Received Amount of upfront payment received. Entity Interactive Data Current Entity Interactive Data Current Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Entity Small Business Entity Small Business Comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent 2029 Lessee, Operating Lease, Liability, to be Paid, Year Three Termination Date Trading Arrangement Termination Date Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Other long-term assets Other Assets, Noncurrent Document Type Document Type Accrued expenses Total accrued expenses Accrued Liabilities, Current Fair Value as of Grant Date Award Grant Date Fair Value Schedule of Cash Equivalents And Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block] Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Options exercisable Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Reportable Segment Reportable Segment [Member] Reportable Segment Arrangement Duration Trading Arrangement Duration Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Local Phone Number Local Phone Number Entity Address, Postal Zip Code Entity Address, Postal Zip Code Entity Registrant Name Entity Registrant Name Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Options vested and expected to vest Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Commitments and contingencies (Note 8) Commitments and Contingencies Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Executive Category: Executive Category [Axis] Options expired (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period Liabilities and Stockholders' Equity Liabilities and Equity [Abstract] Options exercisable Weighted-Average Remaining Contractual Term Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted-Average Remaining Contractual Term Unallocated internal costs Unallocated Internal Costs [Member] In relation to unallocated internal costs. Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] New Lease Agreement New Lease Agreement [Member] The new lease agreement. Marketable Securities [Abstract] Award Type [Domain] Award Type [Domain] Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount 2026 Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year Fair Value Measurements Fair Value Disclosures [Text Block] Significant Unobservable Inputs (Level 3) Fair Value, Inputs, Level 3 [Member] U.S. Government agency securities US Government Agencies Debt Securities [Member] Expected term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Lessee, operating lease, term of contract (in years) Lessee, Operating Lease, Term of Contract PEO Name PEO Name Accrued expenses Increase (Decrease) in Accrued Liabilities Cash, cash equivalents and marketable securities Cash, Cash Equivalents, and Short-Term Investments Other segment items Segment Reporting, Other Segment Item, Amount Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Entity Tax Identification Number Entity Tax Identification Number Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] Options exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Accrued professional and consulting expenses Accrued Professional Fees, Current Accounts payable Increase (Decrease) in Accounts Payable Other accrued expenses Other Accrued Liabilities, Current Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Non-NEOs Non-NEOs [Member] Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Organization and Basis of Presentation Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Stock-based compensation Share-Based Payment Arrangement, Noncash Expense Loss on disposal of property and equipment Gain (Loss) On Disposal Of Property And Equipment The amount of gain (loss) on disposal of property and equipment. Conversion of Class B common stock into Class A common stock (in shares) Stock Issued During Period, Shares, Conversion of Convertible Securities Net loss per share, basic (in dollars per share) Earnings Per Share, Basic Total current assets Assets, Current Statistical Measurement [Axis] Statistical Measurement [Axis] Insider Trading Arrangements [Line Items] Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Award Type [Axis] Award Type [Axis] Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] CTX-343 CTX-343 [Member] In relation to CTX-343 Accumulated deficit Accumulated deficit Retained Earnings (Accumulated Deficit) Product and Service [Axis] Product and Service [Axis] Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Class A and Class B Common Stock Common Stock [Member] Fair Value Debt securities, fair value Debt Securities, Available-for-Sale Expected volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Debt securities, available-for-sale, number of positions Debt Securities, Available-For-Sale, Number of Positions Number of investments in debt securities measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale). Cover [Abstract] Cover [Abstract] Dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Equity Awards Adjustments Equity Awards Adjustments [Member] License Agreement Collaborative Arrangement Disclosure [Text Block] Total liabilities and stockholders' equity Liabilities and Equity Common stock options Share-Based Payment Arrangement, Option [Member] Segments [Axis] Segments [Axis] Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Plan Name [Axis] Plan Name [Axis] Tabular List, Table Tabular List [Table Text Block] Additional paid-in-capital Additional Paid in Capital Other expense, net Other Nonoperating Income (Expense) Short-Term Investments Short-Term Investments [Member] Name Awards Close in Time to MNPI Disclosures, Individual Name Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] Outstanding Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value General and administrative General and Administrative Expense Sale of stock, price per share (in dollars per share) Sale of Stock, Price Per Share Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Preferred stock, $0.001 par value; authorized shares—10,000,000 at June 30, 2026 and December 31, 2025; no shares issued or outstanding at June 30, 2026 and December 31, 2025. 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Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Additional Paid-in Capital Additional Paid-in Capital [Member] Entity Filer Category Entity Filer Category Fair Value Debt Securities, Available-for-Sale, Unrealized Loss Position Convertible Class B common stock Convertible Class B Common Stock [Member] Convertible Class B Common Stock Name Trading Arrangement, Individual Name Cash and cash equivalents Cash and Cash Equivalent Operating lease expenses Operating Lease, Expense Company Selected Measure Amount Company Selected Measure Amount Depreciation and amortization Depreciation, Depletion and Amortization Options vested and expected to vest Weighted-Average Remaining Contractual Term Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Accretion of premiums/discounts on marketable securities, net Investment Income, Net, Amortization of Discount and Premium Stock, Class of Stock [Table] Stock, Class of Stock [Table] Commercial paper Commercial Paper, Not Included with Cash and Cash Equivalents [Member] Current assets: Assets, Current [Abstract] Weighted-average remaining lease term Operating Lease, Weighted Average Remaining Lease Term Non-PEO NEO Non-PEO NEO [Member] Entity Address, Address Line One Entity Address, Address Line One Adjustments to reconcile net loss to cash used in operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Noncash Item [Abstract] Award Timing Method Award Timing Method [Text Block] Net decrease in cash and cash equivalents Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Cash Equivalents and Marketable Securities Cash, Cash Equivalent, and Marketable Security [Text Block] Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Employee Stock Ownership Plan (ESOP), Plan [Domain] Employee Stock Ownership Plan (ESOP), Plan [Domain] Net loss Net loss Net loss Net loss Net Income (Loss) Attributable to Parent Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Statement [Table] Statement [Table] Restatement Determination Date: Restatement Determination Date [Axis] Proceeds from exercise of stock options Proceeds from Stock Options Exercised Discovery programs Discovery Programs [Member] In relation to discovery programs. Certificates of deposits Certificates of Deposit [Member] Interest income Investment Income, Interest Options exercisable (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Cash and Cash Equivalents [Axis] Cash and Cash Equivalents [Axis] Accrued Liabilities [Abstract] Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block]