Segment Reporting - Schedule of Segment Reporting Information, by Segment (Details) - USD ($) $ in Thousands |
3 Months Ended | 6 Months Ended | ||||
|---|---|---|---|---|---|---|
Jun. 30, 2026 |
Mar. 31, 2026 |
Jun. 30, 2025 |
Mar. 31, 2025 |
Jun. 30, 2026 |
Jun. 30, 2025 |
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| Significant segment expenses | ||||||
| Research and development | $ 12,702 | $ 14,063 | $ 24,349 | $ 27,775 | ||
| General and administrative | 4,726 | 3,839 | 9,983 | 8,237 | ||
| Total operating expenses | 17,428 | 17,902 | 34,332 | 36,012 | ||
| Loss from operations | (17,428) | (17,902) | (34,332) | (36,012) | ||
| Interest income | 2,342 | 2,029 | 4,847 | 4,279 | ||
| Net loss | (15,154) | $ (14,456) | (16,040) | $ (15,990) | (29,610) | (32,030) |
| Reportable Segment | ||||||
| Significant segment expenses | ||||||
| General and administrative | 4,726 | 3,839 | 9,983 | 8,237 | ||
| Total operating expenses | 17,428 | 17,902 | 34,332 | 36,012 | ||
| Loss from operations | (17,428) | (17,902) | (34,332) | (36,012) | ||
| Interest income | 2,342 | 2,029 | 4,847 | 4,279 | ||
| Other segment items | (68) | (167) | (125) | (297) | ||
| Net loss | (15,154) | (16,040) | (29,610) | (32,030) | ||
| Discovery programs | Reportable Segment | ||||||
| Significant segment expenses | ||||||
| Research and development | 1,317 | 1,328 | 2,743 | 2,710 | ||
| Unallocated internal costs | Reportable Segment | ||||||
| Significant segment expenses | ||||||
| Research and development | 4,176 | 3,338 | 7,822 | 6,121 | ||
| PIPE-791 | Reportable Segment | ||||||
| Significant segment expenses | ||||||
| Research and development | 7,127 | 6,178 | 13,178 | 11,732 | ||
| PIPE-307 | Reportable Segment | ||||||
| Significant segment expenses | ||||||
| Research and development | (259) | 2,160 | (8) | 4,775 | ||
| CTX-343 | Reportable Segment | ||||||
| Significant segment expenses | ||||||
| Research and development | $ 341 | $ 1,059 | $ 614 | $ 2,437 | ||
| X | ||||||||||
- Definition The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount before accretion (amortization) of purchase discount (premium) of interest income on nonoperating securities. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Generally recurring costs associated with normal operations except for the portion of these expenses which can be clearly related to production and included in cost of sales or services. Includes selling, general and administrative expense. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition The net result for the period of deducting operating expenses from operating revenues. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- References No definition available.
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- Definition Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount of other expense (income) and loss (gain) calculated as difference between segment revenue and separately disclosed expense category to arrive at segment profit (loss). Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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