0000001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 9952156 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY (DEFICIT) (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952157 - Disclosure - NATURE OF BUSINESS link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - BASIS OF PRESENTATION AND PRINCIPLES OF CONSOLIDATION link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - NET PRODUCT REVENUES link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - COLLABORATIONS link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - FAIR VALUE MEASUREMENTS link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - MARKETABLE DEBT SECURITIES link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - OTHER BALANCE SHEET DETAILS link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - CONVERTIBLE DEBT AND OTHER FINANCING link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - LIABILITIES RELATED TO THE SALE OF FUTURE ROYALTIES AND DEVELOPMENT FUNDING link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - STOCK-BASED COMPENSATION link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - NET INCOME (LOSS) PER COMMON SHARE link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - COMMITMENTS AND CONTINGENCIES link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - SEGMENT INFORMATION link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - BASIS OF PRESENTATION AND PRINCIPLES OF CONSOLIDATION (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - NET PRODUCT REVENUES (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - COLLABORATIONS (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - FAIR VALUE MEASUREMENTS (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - MARKETABLE DEBT SECURITIES (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - OTHER BALANCE SHEET DETAILS (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - LIABILITIES RELATED TO THE SALE OF FUTURE ROYALTIES AND DEVELOPMENT FUNDING (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - STOCK-BASED COMPENSATION (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - NET INCOME (LOSS) PER COMMON SHARE (Tables) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - SEGMENT INFORMATION (Tables) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - NATURE OF BUSINESS (Details) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - NET PRODUCT REVENUES - Schedule of Net Product Revenues (Detail) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - NET PRODUCT REVENUES - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - NET PRODUCT REVENUES - Schedule of Balances and Activity in Each Product Revenue Allowance and Reserve Category (Detail) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - COLLABORATIONS - Revenue from Collaborators (Detail) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - COLLABORATIONS - Balance of Receivables and Contract Liabilities Related to Collaboration Agreements (Detail) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - COLLABORATIONS - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - COLLABORATIONS - Schedule of Transaction Price Allocated (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - COLLABORATIONS - Schedule of Net Revenues From Collaborations (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - COLLABORATIONS - Schedule of Revenue Recognized under Collaboration (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - FAIR VALUE MEASUREMENTS - Fair Value of Assets Measured on a Recurring Basis (Detail) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - MARKETABLE DEBT SECURITIES - Schedule of Marketable Debt Securities (Detail) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - MARKETABLE DEBT SECURITIES - Schedule of Fair Value of Marketable Debt Securities (Detail) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - OTHER BALANCE SHEET DETAILS - Schedule of Inventory (Detail) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - OTHER BALANCE SHEET DETAILS - Narrative (Detail) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - OTHER BALANCE SHEET DETAILS - Schedule of Reconciliation of Cash, Cash Equivalents and Restricted Cash (Detail) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - OTHER BALANCE SHEET DETAILS - Schedule of Changes in Accumulated Other Comprehensive Loss (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - CONVERTIBLE DEBT AND OTHER FINANCING - Convertible Senior Notes (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - CONVERTIBLE DEBT AND OTHER FINANCING - Capped Call Transactions (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - CONVERTIBLE DEBT AND OTHER FINANCING - Revolving Credit Agreement (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - LIABILITIES RELATED TO THE SALE OF FUTURE ROYALTIES AND DEVELOPMENT FUNDING - Additional Information (Detail) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - LIABILITIES RELATED TO THE SALE OF FUTURE ROYALTIES AND DEVELOPMENT FUNDING - Schedule of Fair Value, Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - LIABILITIES RELATED TO THE SALE OF FUTURE ROYALTIES AND DEVELOPMENT FUNDING - Schedule of Future Royalties (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - STOCK-BASED COMPENSATION - Schedule of Share-Based Compensation Expenses Included Operating Costs and Expense (Detail) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - STOCK-BASED COMPENSATION - Schedule of Share-Based Compensation Expenses Included Operating Costs and Expense (Detail) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - NET INCOME (LOSS) PER COMMON SHARE - Schedule of Basic and Diluted Net (Loss) Income Per Share (Detail) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - NET INCOME (LOSS) PER COMMON SHARE - Common Share Equivalents Excluded from Calculation of Net Loss Per Common Share (Detail) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - NET INCOME (LOSS) PER COMMON SHARE - Narrative (Detail) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - COMMITMENTS AND CONTINGENCIES (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - SEGMENT INFORMATION - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - SEGMENT INFORMATION - Schedule of Expenses by Segment (Details) link:presentationLink link:calculationLink link:definitionLink