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  <xs:element id="pebo_OtherInvestmentSecurities" abstract="false" name="OtherInvestmentSecurities" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_DepositsAndRepurchaseAgreementsMember" abstract="true" name="DepositsAndRepurchaseAgreementsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_FederalHomeLoanBankAndFederalReserveBankMember" abstract="true" name="FederalHomeLoanBankAndFederalReserveBankMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_PremiumFinanceLoanMember" abstract="true" name="PremiumFinanceLoanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_ConsumerIndirectLoanMember" abstract="true" name="ConsumerIndirectLoanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_ConsumerDirectLoanMember" abstract="true" name="ConsumerDirectLoanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_FinancingReceivableExcludingAccruedInterest90DaysOrMorePastDueStillAccruingNumberOfLoans" abstract="false" name="FinancingReceivableExcludingAccruedInterest90DaysOrMorePastDueStillAccruingNumberOfLoans" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="pebo_FinancingReceivableExcludingAccruedInterest90DaysOrMorePastDueStillAccruingPeriodIncreaseDecrease" abstract="false" name="FinancingReceivableExcludingAccruedInterest90DaysOrMorePastDueStillAccruingPeriodIncreaseDecrease" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_PercentofLoansConsideredCurrent" abstract="false" name="PercentofLoansConsideredCurrent" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="pebo_FinancingReceivableLoanRelationshipAggregateCreditExposureEvaluationThreshold" abstract="false" name="FinancingReceivableLoanRelationshipAggregateCreditExposureEvaluationThreshold" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_FinancingReceivableCollaterallyDependentLoansNumberOfCustomerRelationships" abstract="false" name="FinancingReceivableCollaterallyDependentLoansNumberOfCustomerRelationships" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="pebo_FinancingReceivableCollaterallyDependentLoansValueOfCustomerRelationshipsIncluded" abstract="false" name="FinancingReceivableCollaterallyDependentLoansValueOfCustomerRelationshipsIncluded" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_LossMember" abstract="true" name="LossMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_IndefiniteLivedIntangibleAssetsGrossExcludingGoodwillAndAcquiredIntangibles" abstract="false" name="IndefiniteLivedIntangibleAssetsGrossExcludingGoodwillAndAcquiredIntangibles" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_IntangibleAssetsNetExcludingGoodwillAndServicingRights" abstract="false" name="IntangibleAssetsNetExcludingGoodwillAndServicingRights" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncompeteAgreements" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNoncompeteAgreements" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_IntangibleAssetFiniteLivedEstimatedAmortizationExpenseAfterYearFour" abstract="false" name="IntangibleAssetFiniteLivedEstimatedAmortizationExpenseAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_RetailCertificateOfDepositAxis" abstract="true" name="RetailCertificateOfDepositAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="pebo_RetailCertificateOfDepositDomain" abstract="true" name="RetailCertificateOfDepositDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_RetailCertificateOfDepositMember" abstract="true" name="RetailCertificateOfDepositMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_BrokeredCertificateOfDepositAxis" abstract="true" name="BrokeredCertificateOfDepositAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="pebo_BrokeredCertificateOfDepositDomain" abstract="true" name="BrokeredCertificateOfDepositDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_BrokeredCertificateOfDepositMember" abstract="true" name="BrokeredCertificateOfDepositMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_DepositsGovernmental" abstract="false" name="DepositsGovernmental" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_TimeDepositMaturitiesAfterYearFour" abstract="false" name="TimeDepositMaturitiesAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_IncreaseDecreaseInStockByClassRollForward" abstract="true" name="IncreaseDecreaseInStockByClassRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="pebo_ChangesRelatedToStockBasedCompensationAwardsAbstract" abstract="true" name="ChangesRelatedToStockBasedCompensationAwardsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="pebo_ShareRepurchaseProgramAuthorizedOnJanuary282021Member" abstract="true" name="ShareRepurchaseProgramAuthorizedOnJanuary282021Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentExcludingGainLossOnSaleOfSecuritiesAndSettlements" abstract="false" name="OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentExcludingGainLossOnSaleOfSecuritiesAndSettlements" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_DividendsPaidOnUnvestedShares" abstract="false" name="DividendsPaidOnUnvestedShares" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_UndistributedEarningsLossAllocatedToUnvestedShares" abstract="false" name="UndistributedEarningsLossAllocatedToUnvestedShares" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_BrokeredDemandDepositsMember" abstract="true" name="BrokeredDemandDepositsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_CashPledgedToPeoplesFromCounterparties" abstract="false" name="CashPledgedToPeoplesFromCounterparties" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_CashPledgedToPeoplesFromCounterpartiesInvestmentSecurities" abstract="false" name="CashPledgedToPeoplesFromCounterpartiesInvestmentSecurities" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_OtherComprehensiveIncomeLossGainLossBeforeReclassificationAndTax" abstract="false" name="OtherComprehensiveIncomeLossGainLossBeforeReclassificationAndTax" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_EquityPlan2006Member" abstract="true" name="EquityPlan2006Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_EmployeeMember" abstract="true" name="EmployeeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_PerformanceBasedVestingMember" abstract="true" name="PerformanceBasedVestingMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_EmployeeStockPurchasePlanDiscount" abstract="false" name="EmployeeStockPurchasePlanDiscount" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="pebo_TimeBasedVestingMember" abstract="true" name="TimeBasedVestingMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_EmployeesMember" abstract="true" name="EmployeesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_NonEmployeeDirectorsMember" abstract="true" name="NonEmployeeDirectorsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_FiduciaryIncomeMember" abstract="true" name="FiduciaryIncomeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_BrokerageIncomeMember" abstract="true" name="BrokerageIncomeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_TransactionFeeMember" abstract="true" name="TransactionFeeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="pebo_CommissionAndFeesFromSaleOfInsurancePolicies" abstract="false" name="CommissionAndFeesFromSaleOfInsurancePolicies" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_PerformanceBasedInsuranceCommissions" abstract="false" name="PerformanceBasedInsuranceCommissions" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_InterchangeElectronicBankingIncome" abstract="false" name="InterchangeElectronicBankingIncome" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_PromotionalAndUsageElectronicBankingIncome" abstract="false" name="PromotionalAndUsageElectronicBankingIncome" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_OngoingMaintenanceFeesForDepositAccounts" abstract="false" name="OngoingMaintenanceFeesForDepositAccounts" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_TransactionalBasedFeesForDepositAccounts" abstract="false" name="TransactionalBasedFeesForDepositAccounts" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_TransactionalBasedFeesIncludedInOtherNonInterestIncome" abstract="false" name="TransactionalBasedFeesIncludedInOtherNonInterestIncome" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_ContractWithCustomerAssetIncreaseInAdditionalIncomeReceivable" abstract="false" name="ContractWithCustomerAssetIncreaseInAdditionalIncomeReceivable" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_ContractWithCustomerLiabilityRollForward" abstract="true" name="ContractWithCustomerLiabilityRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="pebo_ContractWithCustomerLiabilityAdditions" abstract="false" name="ContractWithCustomerLiabilityAdditions" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_ContractWithCustomerLiabilityRevenueRecognizedIncludingOpeningBalance" abstract="false" name="ContractWithCustomerLiabilityRevenueRecognizedIncludingOpeningBalance" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_SalesTypeLeaseVariableLeaseIncomeExpense" abstract="false" name="SalesTypeLeaseVariableLeaseIncomeExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_SalesTypeLeaseInitialDirectCostExpense" abstract="false" name="SalesTypeLeaseInitialDirectCostExpense" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_SalesTypeAndDirectFinancingLeasesLeaseReceivableToBeReceivedAfterYearFour" abstract="false" name="SalesTypeAndDirectFinancingLeasesLeaseReceivableToBeReceivedAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="pebo_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" abstract="false" name="LesseeOperatingLeaseLiabilityToBePaidAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
</xs:schema>
