| Schedule of reconciliation of net income to net cash generated from/(used in) operating activities |
| | | | | | | Six Months Ended June 30, | | | 2026 | | 2025 | | | | (in US$’000) | Net income | | 16,242 | | 455,555 | Adjustments to reconcile net income to net cash generated from/(used in) operating activities | | | | | Depreciation and amortization | | 7,072 | | 6,118 | Impairment of an intangible asset | | 8,941 | | — | Share-based compensation expense — share options | | 971 | | 1,552 | Share-based compensation expense — LTIP | | 3,991 | | 7,691 | Equity in earnings of equity investees, net of tax | | (3,798) | | (23,125) | Dilution loss of investment in ImageneBio, Inc. | | 1,107 | | — | Gain from divestment of an equity investee | | — | | (477,456) | Dividends received from SHPL | | 13,343 | | 6,987 | Changes in right-of-use assets | | (4,187) | | 685 | Other adjustments | | (1,564) | | 1,921 | Changes in operating assets and liabilities | | | | | Accounts receivable | | 9,197 | | 8,596 | Other receivables, prepayments and deposits | | 323 | | (4,943) | Amounts due from related parties | | (764) | | 204 | Inventories | | 222 | | 2,095 | Accounts payable | | (11,887) | | 1,204 | Other payables and accruals | | (5,202) | | (37,433) | Lease liabilities | | 3,720 | | (904) | Amounts due to related parties | | (638) | | 142 | Deferred revenue | | (23,917) | | (22,718) | Others | | (949) | | 935 | Total changes in operating assets and liabilities | | (29,895) | | (52,822) | Net cash generated from/(used in) operating activities | | 12,223 | | (72,894) |
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