REVENUE - Disaggregation of Revenue by Product and Region (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026	Jun. 30, 2025
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	$ 12,973	$ 12,269	$ 24,462	$ 23,470
United States
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	8,991	8,519	16,779	16,392
International
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	3,664	3,481	7,108	6,590
Other
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	318	270	575	488
Growth Portfolio
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	7,560	6,596	13,787	12,159
Opdivo
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	2,485	2,560	4,631	4,824
Opdivo Qvantig
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	261	30	424	38
Orencia
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	1,034	963	1,852	1,733
Yervoy
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	769	728	1,420	1,351
Reblozyl
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	735	568	1,291	1,046
Breyanzi
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	484	344	896	607
Opdualag
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	349	284	644	537
Camzyos
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	416	260	729	419
Zeposia
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	169	150	287	257
Sotyktu
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	87	70	156	126
Krazati
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	55	48	105	96
Cobenfy
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	63	35	119	62
Other Growth products
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	653	557	1,234	1,063
Legacy Portfolio
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	5,422	5,673	10,699	11,311
Eliquis
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	4,481	3,680	8,617	7,245
Revlimid
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	425	838	773	1,774
Pomalyst/Imnovid
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	204	708	717	1,366
Sprycel
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	88	120	160	295
Abraxane
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	55	105	105	210
Other Legacy products
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	170	223	326	421
Other revenue
Segment Reporting, Entity-Wide Information Not Provided as Part of Reportable Segment, Product and Service, Revenue [Line Items]
Total Revenues	$ (9)	$ 0	$ (23)	$ 0