Segment information - Significant Expenses by Segment (Details) $ in Thousands |
3 Months Ended | 6 Months Ended | ||
|---|---|---|---|---|
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Jun. 30, 2026
USD ($)
segment
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Jun. 30, 2025
USD ($)
segment
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Jun. 30, 2026
USD ($)
segment
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Jun. 30, 2025
USD ($)
segment
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| Segment and geographic information | ||||
| Number of operating segments | segment | 1 | 1 | 1 | 1 |
| Number of reportable segments | segment | 1 | 1 | 1 | 1 |
| Total revenues | $ 360,519 | $ 178,875 | $ 633,070 | $ 1,354,971 |
| Net income (loss) attributable to common stockholders | 83,496 | (64,849) | 80,687 | 801,713 |
| Income tax expense (benefit) | 14,049 | (6,203) | 14,396 | 57,063 |
| Amortization | 11,841 | 4,061 | 23,422 | 7,859 |
| Operating segments | Life Science | ||||
| Segment and geographic information | ||||
| Total revenues | 360,519 | 178,875 | 633,070 | 1,354,971 |
| Cost of product, collaboration and license sales | 10,933 | 8,093 | 30,611 | 15,800 |
| Program spend | 42,580 | 49,705 | 80,125 | 97,863 |
| Employee costs | 68,348 | 65,593 | 144,469 | 133,292 |
| Manufacturing costs | 6,232 | 19,519 | 15,317 | 34,470 |
| Administrative costs | 16,547 | 17,896 | 33,236 | 36,310 |
| Occupancy costs | 7,493 | 6,643 | 15,848 | 13,825 |
| Other segment items | 124,890 | 76,275 | 232,777 | 221,698 |
| Net income (loss) attributable to common stockholders | 83,496 | (64,849) | 80,687 | 801,713 |
| Interest income | (18,119) | (20,991) | (36,104) | (38,236) |
| Interest expense | 66,600 | 51,349 | 133,615 | 102,686 |
| Income tax expense (benefit) | 14,049 | (6,203) | 14,396 | 57,063 |
| Depreciation | 4,009 | 3,573 | 7,815 | 7,031 |
| Amortization | 11,841 | 4,061 | 23,422 | 7,859 |
| All other | 46,510 | 44,486 | 89,633 | 85,295 |
| Total other segment items | $ 124,890 | $ 76,275 | $ 232,777 | $ 221,698 |
| X | ||||||||||
- Definition The aggregate total of administrative costs of the reporting entity. No definition available.
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- Definition The cost of product sales, collaboration and license sales excluding amortization of intangible assets and royalties No definition available.
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- Definition Amount of expense for occupancy costs. No definition available.
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- Definition Amount of all other net segment expense not specifically itemized. No definition available.
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- Definition Costs incurred for product candidates before and following a clinical trial. No definition available.
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- Definition The aggregate expense charged against earnings to allocate the cost of intangible assets (nonphysical assets not used in production) in a systematic and rational manner to the periods expected to benefit from such assets. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition The amount of expense recognized in the current period that reflects the allocation of the cost of tangible assets over the assets' useful lives. Includes production and non-production related depreciation. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount of interest expense classified as nonoperating. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount before accretion (amortization) of purchase discount (premium) of interest income on nonoperating securities. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount of expense for salary, wage, profit sharing; incentive and equity-based compensation; and other employee benefit. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition The aggregate costs incurred in the production of goods for sale. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Number of segments reported by the entity. A reportable segment is a component of an entity for which there is an accounting requirement to report separate financial information on that component in the entity's financial statements. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount of other expense (income) and loss (gain) calculated as difference between segment revenue and separately disclosed expense category to arrive at segment profit (loss). Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. No definition available.
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- Details
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- Details
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