Stock award plan - Share-based compensation expense (Details) - USD ($) $ in Thousands	3 Months Ended	6 Months Ended
Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026	Jun. 30, 2025
Stock option plan
Share-based compensation expense	$ 23,291	$ 18,543	$ 46,712	$ 36,603
Research and development
Stock option plan
Share-based compensation expense	10,547	9,030	21,677	17,693
Selling, general and administrative
Stock option plan
Share-based compensation expense	$ 12,744	$ 9,513	$ 25,035	$ 18,910

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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+ Details