| Schedule of significant expense categories by operating segment |
| | | | | | | | | | | | | | | Three months ended June 30, | | Six months ended June 30, | | | 2026 | | 2025 | | 2026 | | 2025 | Total revenues | | $ | 360,519 | | $ | 178,875 | | $ | 633,070 | | $ | 1,354,971 | Less: | | | | | | | | | | | | | Cost of product, collaboration and license sales | | | 10,933 | | | 8,093 | | | 30,611 | | | 15,800 | Program spend | | | 42,580 | | | 49,705 | | | 80,125 | | | 97,863 | Employee costs | | | 68,348 | | | 65,593 | | | 144,469 | | | 133,292 |
Manufacturing costs | | | 6,232 | | | 19,519 | | | 15,317 | | | 34,470 | Administrative costs | | | 16,547 | | | 17,896 | | | 33,236 | | | 36,310 | Occupancy costs | | | 7,493 | | | 6,643 | | | 15,848 | | | 13,825 | Other segment items (a) | | | 124,890 | | | 76,275 | | | 232,777 | | | 221,698 | Segment net income (loss) | | $ | 83,496 | | $ | (64,849) | | $ | 80,687 | | $ | 801,713 | Reconciliation of profit or loss | | | | | | | | | | | | | Adjustments and reconciling items | | | — | | | — | | | — | | | — | Consolidated net income (loss) | | $ | 83,496 | | $ | (64,849) | | $ | 80,687 | | $ | 801,713 |
| (a) | Other segment items includes the following: |
| | | | | | | | | | | | | | | | Three months ended June 30, | | | Six months ended June 30, | | | | 2026 | | 2025 | | | 2026 | | 2025 | Interest income | | $ | (18,119) | | $ | (20,991) | | $ | (36,104) | | $ | (38,236) | Interest expense | | | 66,600 | | | 51,349 | | | 133,615 | | | 102,686 | Income tax expense (benefit) | | | 14,049 | | | (6,203) | | | 14,396 | | | 57,063 | Depreciation | | | 4,009 | | | 3,573 | | | 7,815 | | | 7,031 | Amortization | | | 11,841 | | | 4,061 | | | 23,422 | | | 7,859 | All other (b) | | | 46,510 | | | 44,486 | | | 89,633 | | | 85,295 | Total other segment items | | $ | 124,890 | | $ | 76,275 | | $ | 232,777 | | $ | 221,698 |
| (b) | All other includes cost of goods sold, royalty, travel and entertainment, distribution costs, bad debt expense, finance costs, contract labor costs, stock compensation expense, change in the fair value of contingent consideration, and other expense. |
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