0000001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - Condensed Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - Condensed Consolidated Balance Sheets (parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - Condensed Consolidated Statements of Operations link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - Condensed Consolidated Statements of Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - Condensed Consolidated Statements of Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 9952156 - Statement - Condensed Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 9952157 - Disclosure - Overview and Basis of Presentation link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Marketable Securities link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Inventory link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Leases link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Accrued Expenses link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Product Revenue link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Share-Based Payments link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Net Loss per Share link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Segment Information link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Marketable Securities (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Inventory (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Accrued Expenses (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Product Revenue (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Share-Based Payments (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Net Loss per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Segment Information (Tables) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Overview and Basis of Presentation (Details) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Fair Value Measurements - Summary of Cash Equivalents and Marketable Securities Measured at Fair Value on a Recurring Basis (Details) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Fair Value Measurements - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Marketable Securities - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Marketable Securities - Schedule of Marketable Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Marketable Securities - Schedule of Marketable Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Inventory (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Inventory (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Leases - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Leases - Schedule of Lease Expense and Other Information Related to Leases (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Leases - Schedule of Undiscounted Minimum Rental Commitments under Non-cancelable Leases (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Leases - Schedule of Undiscounted Minimum Rental Commitments under Non-cancelable Leases (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Leases - Schedule of Future Minimum Lease Payments to be Received under the Long-term Sublease Agreements (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Accrued Expenses (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Product Revenue - Schedule of Product Revenue, Net (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Product Revenue - Schedule of Product Revenue Allowance and Reserve (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Product Revenue - Schedule of Revenue-related Reserves (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Product Revenue - Schedule of Changes in Contract Assets (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Share-Based Payments - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Share-Based Payments - Schedule of Company's Stock Option Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Share-Based Payments - Schedule of RSU Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Share-Based Payments - Schedule of PSU, Market-based Stock Unit or MSU Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Share-Based Payments - Schedule of Stock-Based Compensation Expense by Award Type Included within the Condensed Consolidated Statements of Operations (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Share-Based Payments - Schedule of Expenses Related to Stock Options and Stock-based Awards (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Share-Based Payments - Schedule of Expenses Related to Stock Options and Stock-based Awards (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Net Loss per Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Segment Information (Details) link:presentationLink link:calculationLink link:definitionLink