Document and Entity Information Document Information [Table] Document Information [Line Items] Document Type Document Quarterly Report Document Period End Date Document Transition Report Entity File Number Entity Registrant Name Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Address, Address Line One Entity Address, Postal Zip Code Entity Address, City or Town Entity Address, Country Country Region City Area Code Local Phone Number Title of 12(b) Security Trading Symbol Security Exchange Name Entity Current Reporting Status Entity Interactive Data Current Entity Filer Category Entity Small Business Entity Emerging Growth Company Entity Shell Company Entity Common Stock, Shares Outstanding Entity Central Index Key Current Fiscal Year End Date Document Fiscal Year Focus Document Fiscal Period Focus Amendment Flag CONSOLIDATED BALANCE SHEETS Assets, Current [Abstract] Current assets Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Debt Securities, Held-to-Maturity, Amortized Cost, after Allowance for Credit Loss, Current Current investment securities Amortized cost Accounts Receivable, Net, Current Accounts receivable Prepaid Expense, Current Prepaid expenses The balance of other current assets and receivables. Other current assets and receivables Other current assets and receivables Assets, Current Total current assets Assets, Noncurrent [Abstract] Non-current assets Property, Plant and Equipment, Net. Property, plant and equipment, net Other Long-Term Investments Other investments Total Operating Lease, Right-of-Use Asset Operating lease right-of-use assets Intangible Assets, Net (Excluding Goodwill) Intangible assets, net Goodwill Goodwill Deferred Income Tax Assets, Net Deferred tax assets, net Other Assets, Noncurrent Other non-current assets Assets, Noncurrent Total non-current assets Assets Total assets Liabilities, Current [Abstract] Current liabilities Accounts Payable, Current Accounts payable Accrued Liabilities, Current Accrued expenses and other current liabilities Total Value of outstanding derivative securities that permit the holder the right to purchase securities (classified as liability) from the issuer at a specified price, classified as current. Warrant Liability, Current Liability related to pre-funded warrants Operating Lease, Liability, Current Current portion of operating lease liabilities Liabilities, Current Total current liabilities Liabilities, Noncurrent [Abstract] Non-current liabilities Long-term Debt, Excluding Current Maturities Long-term debt The amount of non current portion of liability from royalty financing agreement. Liability from Royalty Financing Agreement, Non Current Ending balance Beginning balance Liability from royalty financing agreement Operating Lease, Liability, Noncurrent Operating lease liabilities, net of current portion Business Combination, Contingent Consideration, Liability, Noncurrent Ending Balance Beginning Balance Contingent consideration Deferred Income Tax Liabilities, Net Deferred tax liability, net Other Liabilities, Noncurrent Other non-current liabilities, net of current portion Liabilities, Noncurrent Total non-current liabilities Liabilities Total liabilities Commitments and Contingencies. Commitments and contingencies Stockholders' Equity Attributable to Parent [Abstract] Shareholders' equity Common Stock, Value, Issued Ordinary shares, €0.05 par value: 100,000,000 shares authorized at June 30, 2026, and 80,000,000 at December 31, 2025, and 69,334,839 and 62,336,717 shares issued and outstanding at June 30, 2026, and December 31, 2025, respectively. Additional Paid in Capital Additional paid-in-capital Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive loss Retained Earnings (Accumulated Deficit) Accumulated deficit Stockholders' Equity Attributable to Parent Ending balance Beginning balance Total shareholders' equity Liabilities and Equity Total liabilities and shareholders' equity Statement [Table] Statement [Line Items] Common Stock, Par or Stated Value Per Share Ordinary shares, par value (in euros per share) Common Stock, Shares Authorized Shares authorized Ordinary shares, authorized Common Stock, Shares, Issued Ordinary shares, issued Common Stock, Shares, Outstanding Ending balance (in shares) Beginning balance (in shares) Ordinary shares, outstanding CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS Revenue from Contract with Customer, Excluding Assessed Tax License revenues Revenues Total revenues Operating Expenses [Abstract] Operating expenses: Cost of Goods and Services Sold Cost of license revenues Research and Development Expense Research and development expenses Selling, General and Administrative Expense. Selling, general and administrative expenses Costs and Expenses Total operating expenses Other Operating Income Other income Other Expenses Other expense Operating Income (Loss) Loss from operations Investment Income, Interest Interest income Interest Expense Interest expense Foreign Currency Transaction Gain (Loss), before Tax Foreign currency (losses) / gains, net Other Nonoperating Income (Expense). Other non-operating (losses), net Other reconciling items Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest Loss before income tax expense Income Tax Expense (Benefit) Income tax expense Net loss Loss for the period Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Other comprehensive loss: Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent Foreign currency translation gains / (losses), net Comprehensive Income (Loss), Net of Tax, Attributable to Parent Total comprehensive loss Earnings Per Share, Basic [Abstract] Loss per ordinary share - basic Earnings Per Share, Basic Basic net loss per ordinary share Earnings Per Share, Diluted [Abstract] Loss per ordinary share - diluted Earnings Per Share, Diluted Diluted net loss per ordinary share Weighted Average Number of Shares Outstanding, Basic Weighted average shares - basic Weighted Average Number of Shares Outstanding, Diluted Weighted average shares - diluted CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY / (DEFICIT) Equity Components [Axis] Equity Component [Domain] Ordinary shares Ordinary shares Additional paid-in capital Additional paid-in capital Accumulated other comprehensive income / (loss) Accumulated other comprehensive loss gain / (loss) Accumulated deficit Accumulated deficit Increase (Decrease) in Stockholders' Equity [Roll Forward] CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY / (DEFICIT) Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Other comprehensive gain (loss), net Stock Issued During Period, Value, New Issues Follow-on public offering Stock Issued During Period, Shares, New Issues Follow-on public offering (in shares) Stock Issued During Period, Value, Stock Options Exercised Exercises of share options Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Exercised (in shares) Exercises of share options (in shares) Stock Issued During Period, Value, Share-based Compensation, Gross Restricted and performance share units distributed during the period Stock Issued During Period, Shares, Share-based Compensation, Gross Restricted and performance share units distributed during the period (in shares) Stock Issued During Period, Value, Employee Stock Purchase Plan Issuance of ordinary shares relating to employee stock purchase plan Stock Issued During Period, Shares, Employee Stock Purchase Plans Issuance of ordinary shares relating to employee stock purchase plan (in shares) Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition Share-based compensation expense CONSOLIDATED STATEMENTS OF CASH FLOWS Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Cash flows from operating activities Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net loss Adjustments, Noncash Items, to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Depreciation, Depletion and Amortization, Nonproduction Depreciation and amortization expense Depreciation and amortization Amortization of Debt Discount (Premium) Amortization of discount on investment securities Share-based Compensation. Share-based compensation expense The amount of interest expense net of interest paid on royalty financing agreement. Royalty Financing Agreement, Interest Expense Interest expense - Royalty Financing Agreement Royalty financing agreement interest expense, net of interest paid Interest expense for the period Amount of deferred income tax expense (benefit) with adjustments pertaining to income (loss) from continuing operations. Deferred Income Tax Expense (Benefit) with adjustments Deferred tax expense Business Combination, Contingent Consideration Arrangements, Change in Amount of Contingent Consideration, Liability Fair value (loss) / gain - contingent consideration Changes in fair value of contingent consideration Unrealized change in fair value (presented within Research and development expenses) Fair Value Adjustment of Warrants Changes in fair value of liability related to pre-funded warrants Fair value loss - Liability related to pre-funded warrants Foreign Currency Transaction Gain (Loss), Unrealized Unrealized foreign exchange losses / (gains), net Other Noncash Income (Expense) Other items, net Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: The amount of increase (decrease) in accounts receivable and contract assets, prepaid expenses, and other current assets and receivables. Increase (Decrease) in Accounts Receivable and Contract Assets, Prepaid Expenses, and Other Current Assets and Receivables Accounts receivable, prepaid expenses, and other current assets and receivables Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities Accrued expenses, other liabilities, and operating leases Net Cash Provided by (Used in) Operating Activities, Continuing Operations Net cash used in operating activities Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Cash flows from investing activities Proceeds from Maturities, Prepayments and Calls of Held-to-Maturity Securities Proceeds on maturity of debt securities Payments to Acquire Held-to-Maturity Securities Investments in debt securities Payments to Acquire Property, Plant, and Equipment Purchases of property, plant, and equipment Net Cash Provided by (Used in) Investing Activities, Continuing Operations Net cash generated from investing activities Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Cash flows from financing activities Sale of Stock, Consideration Received on Transaction Net proceeds Proceeds from follow-on public offering of ordinary shares, net of issuance costs Proceeds from Issuance of Shares under Incentive and Share-based Compensation Plans, Including Stock Options Proceeds from issuance of ordinary shares related to employee stock options and purchase plans Net Cash Provided by (Used in) Financing Activities, Continuing Operations Net cash generated from financing activities Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents Currency effect on cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Net increase in cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents Cash, cash equivalents and restricted cash at the end of period Cash, cash equivalents and restricted cash at the beginning of period Total cash, cash equivalents and restricted cash Restricted Cash, Noncurrent Restricted cash Restricted cash related to leasehold and other deposits Supplemental Cash Flow Elements [Abstract] Supplemental cash flow disclosures: Interest Paid Cash paid for interest General business information Nature of Operations [Text Block] General business information Summary of significant accounting policies Basis of Presentation and Significant Accounting Policies [Text Block] Summary of significant accounting policies Current investment securities Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Current investment securities Fair value measurement. Fair Value Disclosures [Text Block] Fair value measurement Accrued expenses and other current liabilities The entire disclosure for accrued expenses and other current liabilities. Accrued Expenses and Other Current Liabilities Disclosure [Text Block] Accrued expenses and other current liabilities Long-term debt Long-term Debt [Text Block] Long-term debt No definition available. Royalty Financing Agreement The entire disclosure for royalty financing agreement. Royalty Financing Agreement [Text Block] Royalty Financing Agreement Shareholders' equity Stockholders' Equity Note Disclosure [Text Block] Shareholders' equity Share-based compensation Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based compensation Share-based compensation Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Share-based compensation Segment reporting Segment Reporting Disclosure [Text Block] Segment reporting Other investments and concentration of credit risk Investment [Text Block] Other investments and concentration of credit risk Income taxes Income Tax Disclosure [Text Block] Income taxes Basic and diluted loss per share Earnings Per Share [Text Block] Basic and diluted loss per share Commitments and contingencies Commitments and Contingencies Disclosure [Text Block] Commitments and contingencies Subsequent events Subsequent Events [Text Block] Subsequent events Basis of Accounting, Policy [Policy Text Block] Basis of preparation Disclosure of accounting policies for Unaudited interim financial information. Unaudited Interim Financial Information [Policy Text Block] Unaudited interim financial information Use of Estimates, Policy [Policy Text Block] Use of estimates Significant Accounting Policies [Text Block] Accounting policies New Accounting Pronouncements, Policy [Policy Text Block] Recent accounting pronouncements Debt Securities, Held-to-Maturity [Table Text Block] Schedule of investments in government debt securities Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Schedule of assets and liabilities measured at fair value on recurring basis Tabular disclosure of changes in fair value of contingent consideration. Schedule of Changes in Fair Value of Contingent Consideration [Table Text Block] Schedule of changes in fair value of contingent consideration Tabular disclosure of changes in fair value of warrant liability. Schedule of Changes in Fair Value of Warrant Liability [Table Text Block] Schedule of changes in fair value of pre funded warrants Schedule of Accounts Payable and Accrued Liabilities [Table Text Block] Schedule of accrued expenses and other current liabilities Tabular disclosure for movement in the liability related to royalty financing agreement Schedule of Movement in Liability Related to Royalty Financing Agreement [Table Text Block] Schedule of movement in the liability related to royalty financing agreement Plan Name [Axis] Stock-Based Compensation Plans [Domain] Represents the information pertaining to 2014 Plan. Plan In 2014 [Member] 2014 Plan Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] Schedule of share-based compensation expense by classification included in consolidated statements of operations and comprehensive loss Schedule of Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Table Text Block] Schedule of share-based compensation expense / (income) Schedule of Unrecognized Compensation Cost, Nonvested Awards [Table Text Block] Schedule of unrecognized compensation expense related to unvested awards Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] Summary of option activity Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule of weighted-average assumptions for fair value of option issued Schedule of Share-based Compensation, Restricted Stock Units Award Activity [Table Text Block] Summary of RSUs activity Share-based Compensation, Performance Shares Award Unvested Activity [Table Text Block] Summary of PSUs activity Schedule of Segment Reporting Information, by Segment [Table Text Block] Schedule of segment reporting Investment [Table Text Block] Schedule of other investments Tabular disclosure of potential dilutive common shares. Schedule of Potential Dilutive Common Shares [Table Text Block] Schedule of potentially dilutive ordinary shares Debt Securities, Held-to-Maturity [Table] Debt Securities, Held-to-Maturity [Table] Financial Instrument [Axis] Financial Instrument [Axis] Fair Value Option Grouping Fair Value Option Grouping Debt Security, Government, Non-US [Member] Government debt securities (held-to-maturity) Schedule of Held-to-Maturity Securities [Line Items] Current investment securities Debt Securities, Current [Abstract] Current investments securities: Amount of accumulated unrecognized gain on investment in current portion of debt security measured at amortized cost (held-to-maturity). Debt Securities Current, Held-to-Maturity, Accumulated Unrecognized Gain Gross unrealized holding gains Debt Securities, Current Estimated fair value Debt Securities, Held-to-Maturity, Allowance for Credit Loss Expected credit loss Fair Value Measurements, Recurring and Nonrecurring [Table] Measurement Frequency [Axis] Fair Value, Measurement Frequency [Domain] Recurring Fair Value Measurements Recurring Fair Value Measurements Fair Value, Hierarchy [Axis] Fair Value Plan Asset Measurement [Domain] Fair value hierarchy Level 1 Quoted prices in active markets (Level 1) Fair value hierarchy Level 2 Significant other observable inputs (Level 2) Fair value hierarchy Level 3 Significant unobservable inputs (Level 3) Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Assets, Fair Value Disclosure [Abstract] Assets: Cash and Cash Equivalents, Fair Value Disclosure Cash and cash equivalents Assets, Fair Value Disclosure Total assets Liabilities, Fair Value Disclosure [Abstract] Liabilities: Fair value of warrant liabilities. Warrant Liability, Fair Value Disclosure Ending balance Beginning balance Liability related to pre-funded warrants Fair value of contingent consideration in a business combination that is classified in other non-current liabilities. Contingent Consideration Classified As Liability Fair Value Disclosure Contingent consideration The amount of consideration payable for post acquisition services. Use for fair value note also Consideration for Post Acquisition Services Consideration for post-acquisition services Financial and Nonfinancial Liabilities, Fair Value Disclosure Total liabilities Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Business Acquisition [Axis] Business Acquisition, Acquiree [Domain] This member stands for Corlieve Therapeutics SAS. uniQure France uniQure France [S.A.S] Scenario [Axis] Scenario [Domain] Represents the information pertaining to 100% likelihood of AMT-260 advancing into clinical development. One hundred percent likelihood of AMT-260 advancing into clinical development One hundred percent likelihood of AMT-260 advancing into clinical development Range [Axis] Range [Domain] Maximum Maximum Minimum Minimum Fair value measurement The amount of contingent consideration payable upon achievement of contractually defined milestones. Business Acquisition Contingent Consideration Payable Upon Achievement of Contractually Defined Milestones Contingent consideration payable upon achievement of contractually defined milestones The fair value of contingent consideration discount rate percentage. Fair Value of Contingent Consideration Discount Rate Percentage Contingent consideration discount rate percentage Percentage of increase in Probability of Success in clinical development. Percentage of Increase in Probability of Success in Clinical Development Percentage of increase in Probability of Success Adjustments to contingent consideration resulting from foreign currency translation adjustments. Contingent Consideration, Foreign Currency Translation Adjustments Currency translation effects Class of Warrant or Right [Table] Class of Warrant or Right [Axis] Class of Warrant or Right [Domain] Represents the information pertaining to pre-funded warrants. Pre-Funded Warrants [Member] Pre-Funded Warrants Class of Warrant or Right Class of Warrant or Right, Number of Securities Called by Warrants or Rights Warrants to purchase shares Share Price Public offering price Class of Warrant or Right, Exercise Price of Warrants or Rights Warrants exercise price The amount of currency translation adjustments related to warrants. Warrants, Currency Translation Effects Currency translation effects Carrying value as of the balance sheet date of obligations incurred through that date and payable for serviced provided by vendors not yet billed. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accruals for Services Provided by Vendors Not Yet Billed, Current Accruals for goods received from and services provided by vendors, not yet billed Employee-related Liabilities, Current Personnel-related accruals and liabilities (As of June 30, 2026, $7.2 million (December 31, 2025: $0.0 million) related to cash proceeds from employees' stock option exercises) Accounts Payable, Trade, Current Liability owed to the Purchaser pursuant to the Royalty Financing Agreement (refer to Note 7, "Royalty Financing Agreement") Liability owed to the Purchaser (presented as "Accrued expense and other current liabilities") The amount of current liability related to expected future losses of long term purchase commitments. Long Term Purchase Commitments, Liability, Current Current portion of firm purchase commitment liability (including Genezen CSA termination payment) Other Accrued Liabilities, Current Other current liabilities Proceeds from Stock Options Exercised Cash proceeds from employees' stock option exercises Schedule of Long-term Debt Instruments [Table] Credit Facility [Axis] Credit Facility [Domain] Represents information pertaining to 2025 Amended Facility. Amended Facility 2025 [Member] 2025 Amended Facility Represents information pertaining to 2026 Amended Facility. Amended Facility 2026 [Member] 2026 Amended Facility Debt Instrument Tranche [Axis] Debt Instrument Tranche [Axis] Debt Instrument Tranche [Domain] Debt Instrument Tranche [Domain] Represents information pertaining to tranche based on approval of AMT-130. Debt Instrument, Tranche Based on Approval of AMT-130 [Member] Tranche Based on Approval of AMT-130 Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent event Debt Instrument [Line Items] Long-term debt Line of Credit Facility, Maximum Borrowing Capacity Maximum borrowing capacity Line of Credit, Current Line of credit Foreign Currency Transaction Loss, before Tax Foreign currency loss Foreign Currency Transaction Gain, before Tax Foreign currency gain Interest Expense, Debt Interest expense - Hercules debt facility Interest expense recorded Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Royalty Agreements [Member] Royalty Financing Agreement Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] Income taxes paid Payments to Acquire Royalty Interests in Mining Properties Royalty payments to the Purchaser Debt Instrument, Interest Rate, Effective Percentage Effective interest rate (as a percent) Stock, Class of Stock [Table] Class of Stock [Line Items] Shareholders' equity / (deficit) Sale of Stock, Number of Shares Issued in Transaction Offering expenses payable through public offering Shares Issued, Price Per Share Offering price per share of shares issued An arrangement whereby an employee, consultant, or member of the Board of Directors is entitled to receive in the future, subject to vesting and other restrictions, a number of shares in the entity at a specified price, as defined in the agreement. Share options Share options Restricted share units ("RSUs") Restricted Share Units Performance Share Awards Performance Share Units Employee Stock ESPP Income Statement Location [Axis] Income Statement Location [Domain] Research and Development Expense [Member] Research and development expenses Selling, general and administrative expense Selling, general and administrative expenses This member represents information pertaining to employee share purchase plan. Employee share purchase plan (ESPP) ESPP Employee Share Purchase Plan Represents share-based compensation plan approved at the general meeting of entity's shareholders on January 9, 2014. The 2014 Plan [Member] 2014 Plan This member stands for 2014 Plans and Employee Share Purchase Plan. 2014 Plans and ESPP 2014 Plans and ESPP Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized Increase in authorized shares Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant Ordinary shares available for issue Share-based Compensation Arrangement by Share-based Payment Award, Discount from Market Price, Purchase Date Discounted rate for purchase of shares Allocated Share-based Compensation Expense Share-based compensation expense Share-based compensation expense Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized Unrecognized compensation costs Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition Weighted-average remaining period for recognition (in years) Vesting [Axis] Vesting [Domain] One year from grant date One year from grant date Title of Individual [Axis] Title of Individual [Domain] Represents the member information pertaining to non-executive directors. Non-Executive Directors [Member] Non-Executive Directors Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period Vesting period (in years) Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage Vesting percentage per year Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Number of ordinary shares Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Outstanding at end of the period (in shares) Outstanding at beginning of the period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Forfeited (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Expirations in Period Expired (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Thereof, fully vested and exercisable at end of period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares Outstanding and expected to vest after at end of period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Weighted average exercise price Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Outstanding at end of period (in dollars per share) Outstanding at beginning of the period (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Granted (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Forfeited (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Expired (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Exercised (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Thereof, fully vested and exercisable at end of period (in dollars per share) The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and expected to vest under the stock option plan. Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding And Expected To Vest, Weighted Average Exercise Price Outstanding and expected to vest after at end of the period (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested in Period, Fair Value Total weighted average grant date fair value of options issued during the period (in $ millions) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract] Weighted-average assumptions used to estimate fair value of share options granted during year Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate Expected volatility (as a percent) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum Expected volatility, minimum(as a percent) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum Expected volatility, maximum(as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term Expected terms (in years) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Risk free interest rate (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Risk free interest rate, minimum (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum Risk free interest rate, maximum (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend yield (as a percent) Represents the member information pertaining to other than non-executive directors. Other than Non-Executive Directors [Member] Other than non-executive directors Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Number of shares Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number Non-vested at end of period (in shares) Non-vested at beginning of period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period Granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period Vested (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeited in Period Forfeited (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Weighted average grant-date fair value Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Non-vested at end of period (in dollars per share) Non-vested at beginning of period (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Granted (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Vested (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Forfeited (in dollars per share) Forfeited (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Additional Disclosures [Abstract] Other disclosure Fair value of equity instruments other than options granted. Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Fair value Total weighted average grant date fair value of RSUs granted during the period (in millions) Reconciliation of Operating Profit (Loss) from Segments to Consolidated [Table] Consolidation Items [Axis] Consolidation Items [Domain] Operating Segments [Member] Operating Segment Segment Reporting, Reconciling Item, Excluding Corporate Nonsegment [Member] Material Reconciling Segments [Axis] Segments [Domain] Represents information pertaining to the single reportable segment of the company. Single Reportable Segment [Member] Single Reportable Segment Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items] Segment reporting Number of Operating Segments Number of operating segments Number of Reportable Segments Number of reportable segments Revenue from Contract with Customer, Including Assessed Tax Revenue Labor and Related Expense Employee related expenses Represents the expense for laboratory and development expense. Laboratory And Development Expense Laboratory and development expenses Professional Fees Professional fees Communications and Information Technology Information technology system costs Amount of facility expenses. Facility expenses Facility expenses Segment Reporting, Other Segment Item, Amount Other segment items(1) Segment Reporting, Other Segment Item, Composition, Description Other segment items description Alternative Investment Carrying amount of equity investments Financing Receivable, after Allowance for Credit Loss, Noncurrent Convertible note receivable Concentration Risk [Table] Counterparty Name [Axis] Counterparty Name [Domain] Represents the member information pertaining to Genezen Holdings Inc. and its subsidiary Genezen MA, Inc. (together "Genezen"). Genezen Holdings Inc. and its subsidiary Genezen MA, Inc. [Member] Genezen Represents the Information pertaining to a collaborative agreement entity has with CSL Behring collaboration. CSL Behring collaboration [Member] CSL Behring Concentration Risk [Line Items] The amount of cash outflow associated with the prepayment for the services to be received. Prepayment Amount for Services to be Received Prepayments Financing Receivable, Allowance for Credit Loss, Noncurrent Expected credit losses Deferred Income Tax Expense (Benefit) Deferred tax expense Effective Income Tax Rate Reconciliation, Percent Effective income tax rate Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Enacted tax rate Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Antidilutive Securities [Axis] Antidilutive Securities, Name [Domain] Stock options under 2014 Plans Represents restricted share units and performance share units. Non-vested RSUs and PSUs Non-vested RSUs and PSUs Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Basic and diluted loss per share Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Total anti-dilutive ordinary share equivalents Subsequent Event [Table] Subsequent Event [Line Items] Subsequent events Represents the information pertaining to David Meek. David Meek [Member] David Meek N/A Non-Rule 10b5-1 Arr Modified Flag