v3.26.1
Segment Reporting - Summary of the Significant Segment Expenses (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2026
Mar. 31, 2026
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2026
Jun. 30, 2025
Segment Reporting [Line Items]            
Research and development $ 152,169   $ 99,236   $ 253,175 $ 205,683
Platform and external research and development 14,117   7,425   25,582 15,040
Personnel related 28,793   19,510   57,348 40,212
Stock-based compensation 14,976   10,523   28,057 23,543
Facility-related and other 12,500   7,418   24,381 14,330
Professional and consulting fees 9,975   6,713   17,740 13,689
Interest income (7,788)   (6,625)   (16,544) (13,725)
Interest expense 4,595   94   8,797 94
Other expense (income), net 88   1,597   219 1,687
Net loss 178,556 $ 120,854 110,857 $ 115,361 299,410 226,219
DYNE-251 (DMD)            
Segment Reporting [Line Items]            
Research and development 52,321   29,525   90,069 51,238
DYNE-101 (DM1)            
Segment Reporting [Line Items]            
Research and development $ 48,979   $ 34,677   $ 63,761 $ 80,111