| Summary of the Significant Segment Expenses |
A summary of the significant segment expenses reported to the CODM are shown below for the three and six months ended June 30, 2026 and 2025:
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Three Months Ended June 30, |
|
|
Six Months Ended June 30, |
|
(in thousands) |
|
2026 |
|
|
2025 |
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|
2026 |
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|
2025 |
|
Operating Expenses |
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|
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|
|
|
|
Z-rostudirsen (DMD) |
|
$ |
52,321 |
|
|
$ |
29,525 |
|
|
$ |
90,069 |
|
|
$ |
51,238 |
|
Z-basivarsen (DM1) |
|
|
48,979 |
|
|
|
34,677 |
|
|
|
63,761 |
|
|
|
80,111 |
|
Platform and external research and development |
|
|
14,117 |
|
|
|
7,425 |
|
|
|
25,582 |
|
|
|
15,040 |
|
Personnel related |
|
|
28,793 |
|
|
|
19,510 |
|
|
|
57,348 |
|
|
|
40,212 |
|
Stock-based compensation |
|
|
14,976 |
|
|
|
10,523 |
|
|
|
28,057 |
|
|
|
23,543 |
|
Facility-related and other |
|
|
12,500 |
|
|
|
7,418 |
|
|
|
24,381 |
|
|
|
14,330 |
|
Professional and consulting fees |
|
|
9,975 |
|
|
|
6,713 |
|
|
|
17,740 |
|
|
|
13,689 |
|
Interest income |
|
|
(7,788 |
) |
|
|
(6,625 |
) |
|
|
(16,544 |
) |
|
|
(13,725 |
) |
Interest expense |
|
|
4,595 |
|
|
|
94 |
|
|
|
8,797 |
|
|
|
94 |
|
Other expense (income), net |
|
|
88 |
|
|
|
1,597 |
|
|
|
219 |
|
|
|
1,687 |
|
Net loss |
|
$ |
178,556 |
|
|
$ |
110,857 |
|
|
$ |
299,410 |
|
|
$ |
226,219 |
|
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