v3.26.1
Segment Reprting
6 Months Ended
Jun. 30, 2026
Segment Reporting [Abstract]  
Segment Reporting

9. Segment Reporting

The Company’s segment determination is based on the financial results that are regularly evaluated by the Company’s chief operating decision maker ("CODM") to determine resource allocation and assess performance. The Company's CODM is its chief executive officer. The Company has one operating and one reportable segment. Net long-lived assets are all physically located in the United States and the total assets of the segment equal the total assets presented on the condensed consolidated balance sheet. The primary financial measure by which the CODM evaluates the business is net loss. The CODM uses net loss to monitor budget versus actual results to assess performance of the segment. A summary of the significant segment expenses reported to the CODM are shown below for the three and six months ended June 30, 2026 and 2025:

 

 

 

Three Months Ended June 30,

 

 

Six Months Ended June 30,

 

(in thousands)

 

2026

 

 

2025

 

 

2026

 

 

2025

 

Operating Expenses

 

 

 

 

 

 

 

 

 

 

 

 

Z-rostudirsen (DMD)

 

$

52,321

 

 

$

29,525

 

 

$

90,069

 

 

$

51,238

 

Z-basivarsen (DM1)

 

 

48,979

 

 

 

34,677

 

 

 

63,761

 

 

 

80,111

 

Platform and external research and development

 

 

14,117

 

 

 

7,425

 

 

 

25,582

 

 

 

15,040

 

Personnel related

 

 

28,793

 

 

 

19,510

 

 

 

57,348

 

 

 

40,212

 

Stock-based compensation

 

 

14,976

 

 

 

10,523

 

 

 

28,057

 

 

 

23,543

 

Facility-related and other

 

 

12,500

 

 

 

7,418

 

 

 

24,381

 

 

 

14,330

 

Professional and consulting fees

 

 

9,975

 

 

 

6,713

 

 

 

17,740

 

 

 

13,689

 

Interest income

 

 

(7,788

)

 

 

(6,625

)

 

 

(16,544

)

 

 

(13,725

)

Interest expense

 

 

4,595

 

 

 

94

 

 

 

8,797

 

 

 

94

 

Other expense (income), net

 

 

88

 

 

 

1,597

 

 

 

219

 

 

 

1,687

 

Net loss

 

$

178,556

 

 

$

110,857

 

 

$

299,410

 

 

$

226,219