Segment Information - Segment Information (Details) - Ionis Operations [Member] - USD ($) $ in Thousands |
3 Months Ended | 6 Months Ended | ||||
|---|---|---|---|---|---|---|
Jun. 30, 2026 |
Jun. 30, 2025 |
Jun. 30, 2026 |
Jun. 30, 2025 |
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| Segment Information [Abstract] | ||||||
| Revenue | $ 267,949 | $ 452,049 | $ 514,042 | $ 583,660 | ||
| Cost of sales | 2,563 | 3,541 | 5,398 | 4,904 | ||
| Drug discovery | 29,120 | 30,255 | 57,677 | 57,244 | ||
| Drug development | 103,958 | 117,689 | 208,140 | 230,635 | ||
| Medical affairs | 11,318 | 7,826 | 21,307 | 13,468 | ||
| Manufacturing and development chemistry | 20,639 | 21,545 | 40,947 | 35,826 | ||
| R&D support | 26,974 | 20,607 | 49,405 | 41,159 | ||
| Selling, general and administrative | 130,075 | 81,081 | 262,012 | 148,061 | ||
| Other segment items | [1] | 57,948 | 45,954 | 76,330 | 75,750 | |
| Net income (loss) | $ (114,646) | $ 123,551 | $ (207,174) | $ (23,387) | ||
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- Definition Expenses related to drug development, including expenses for marketed medicines and those in Phase 3 development. No definition available.
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- Definition Expenses related to drug discovery research and advancing the Company's core technology. No definition available.
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- Definition Expenses related to manufacturing and development chemistry for providing drug supplies to drug development and our collaboration partners, including personnel costs, specialized chemicals for oligonucleotide manufacturing, validation batches to support regulatory approvals, laboratory supplies and outside services. No definition available.
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- Definition Expenses related to medical affairs for funding and coordinating investigator-sponsored trials, communicating scientific and clinical information to healthcare providers, medical professionals and patients, and managing publications. No definition available.
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- Definition Expenses related to research and development support such as rent, repair and maintenance for buildings and equipment, utilities, depreciation of laboratory equipment and facilities, amortization of intellectual property, information technology costs, procurement costs and waste disposal costs. No definition available.
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- Definition The aggregate costs related to goods produced and sold and services rendered by an entity during the reporting period. This excludes costs incurred during the reporting period related to financial services rendered and other revenue generating activities. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount of other expense (income) and loss (gain) calculated as difference between segment revenue and separately disclosed expense category to arrive at segment profit (loss). Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition The aggregate total costs related to selling a firm's product and services, as well as all other general and administrative expenses. Direct selling expenses (for example, credit, warranty, and advertising) are expenses that can be directly linked to the sale of specific products. Indirect selling expenses are expenses that cannot be directly linked to the sale of specific products, for example telephone expenses, Internet, and postal charges. General and administrative expenses include salaries of non-sales personnel, rent, utilities, communication, etc. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Details
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