| Schedule of selected financial information with respect to the company's single operating segment |
| | | | | | | | | | | | | | | Three Months Ended | | Six Months Ended | | | June 30, | | June 30, | | | 2026 | | 2025 | | 2026 | | 2025 | Revenue: | | | | | | | | | | | | | Product revenue, net | | $ | 243,600 | | $ | 156,797 | | $ | 457,866 | | $ | 294,582 | License and collaboration revenue | | | - | | | - | | | - | | | - | Total revenue | | | 243,600 | | | 156,797 | | | 457,866 | | | 294,582 | Operating expenses: | | | | | | | | | | | | | Cost of goods sold | | | 23,572 | | | 18,603 | | | 44,368 | | | 36,471 | Collaboration expenses | | | 88,069 | | | 52,418 | | | 163,646 | | | 96,208 | Direct research and development expenses by program: | | | | | | | | | | | | | ARCALYST | | | 332 | | | 171 | | | 673 | | | 526 | KPL-387 | | | 21,442 | | | 8,485 | | | 37,594 | | | 13,663 | KPL-1161 | | | 766 | | | 370 | | | 1,721 | | | 470 | Abiprubart | | | 176 | | | 635 | | | 229 | | | 5,002 | Unallocated research and development expenses | | | 18,183 | | | 9,092 | | | 28,157 | | | 18,417 | Selling, general and administrative | | | 63,866 | | | 46,863 | | | 125,017 | | | 90,393 | Total operating expenses | | | 216,406 | | | 136,637 | | | 401,405 | | | 261,150 | Other income, net (1) | | | 3,951 | | | 2,717 | | | 7,365 | | | 5,010 | Income before income taxes | | | 31,145 | | | 22,877 | | | 63,826 | | | 38,442 | Provision for income taxes | | | (5,713) | | | (5,045) | | | (15,802) | | | (12,071) | Net income | | $ | 25,432 | | $ | 17,832 | | $ | 48,024 | | $ | 26,371 | | | | | | | | | | | | | | Other significant noncash items: | | | | | | | | | | | | | Share-based compensation expense | | $ | 11,636 | | $ | 8,876 | | $ | 21,692 | | $ | 16,624 | Non-cash lease expense | | | 1,011 | | | 924 | | | 2,005 | | | 1,759 | Deferred income taxes | | | 2,661 | | | 2,644 | | | 7,184 | | | 5,637 |
|
| Schedule of total revenue by geographic region of the customer |
| | | | | | | | | | | | | | | Three Months Ended | | Six Months Ended | | | June 30, | | June 30, | | | 2026 | | 2025 | | 2026 | | 2025 | Revenue: | | | | | | | | | | | | | United States | | $ | 243,116 | | $ | 156,506 | | $ | 457,184 | | $ | 294,102 | United Kingdom | | | 484 | | | 291 | | | 682 | | | 480 | Total revenue | | $ | 243,600 | | $ | 156,797 | | $ | 457,866 | | $ | 294,582 |
|