v3.26.1
Document And Entity Information - shares
6 Months Ended
Jun. 30, 2026
Jul. 17, 2026
Cover [Abstract]    
Entity Central Index Key 0000944809  
Entity Registrant Name OPKO Health, Inc.  
Amendment Flag false  
Current Fiscal Year End Date --12-31  
Document Fiscal Period Focus Q2  
Document Fiscal Year Focus 2026  
Document Type 10-Q  
Document Quarterly Report true  
Document Period End Date Jun. 30, 2026  
Document Transition Report false  
Entity File Number 001-33528  
Entity Incorporation, State or Country Code DE  
Entity Tax Identification Number 75-2402409  
Entity Address, Address Line One 4400 Biscayne Blvd.  
Entity Address, City or Town Miami  
Entity Address, State or Province FL  
Entity Address, Postal Zip Code 33137  
City Area Code 305  
Local Phone Number 575-4100  
Title of 12(b) Security Common Stock, par value $0.01 per share  
Trading Symbol OPK  
Security Exchange Name NASDAQ  
Entity Current Reporting Status Yes  
Entity Interactive Data Current Yes  
Entity Filer Category Accelerated Filer  
Entity Small Business false  
Entity Emerging Growth Company false  
Entity Shell Company false  
Entity Common Stock, Shares Outstanding   746,328,225