Alliance Revenue (Details) - USD ($) $ in Millions |
3 Months Ended | 6 Months Ended | ||
|---|---|---|---|---|
Jun. 30, 2026 |
Jun. 30, 2025 |
Jun. 30, 2026 |
Jun. 30, 2025 |
|
| Disclosure of products and services [line items] | ||||
| Alliance Revenue | $ 874 | $ 654 | $ 1,699 | $ 1,293 |
| Enhertu | ||||
| Disclosure of products and services [line items] | ||||
| Alliance Revenue | 1,058 | 834 | ||
| Tezspire | ||||
| Disclosure of products and services [line items] | ||||
| Alliance Revenue | 372 | 285 | ||
| Beyfortus | ||||
| Disclosure of products and services [line items] | ||||
| Alliance Revenue | 123 | 109 | ||
| Datroway | ||||
| Disclosure of products and services [line items] | ||||
| Alliance Revenue | 93 | 14 | ||
| Other royalty income | ||||
| Disclosure of products and services [line items] | ||||
| Alliance Revenue | 51 | 48 | ||
| Other Alliance Revenue | ||||
| Disclosure of products and services [line items] | ||||
| Alliance Revenue | $ 2 | $ 3 | ||