<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:019e640b-6aea-741e-a894-f7d966976722,g:66c406c1-46e7-473c-807f-d89f42c369e3-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:arcroleRef arcroleURI="https://xbrl.org/2023/arcrole/summation-item" xlink:type="simple" xlink:href="https://www.xbrl.org/2023/calculation-1.1.xsd#summation-item"/>
  <link:roleRef roleURI="http://www.santander.com/role/CondensedConsolidatedBalanceSheets" xlink:type="simple" xlink:href="san-20260630.xsd#CondensedConsolidatedBalanceSheets"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/CondensedConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_san_TaxLiabilities_019e640b-7266-700e-a58c-69b572b150b0" xlink:href="san-20260630.xsd#san_TaxLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentTaxLiabilities_019e640b-7266-72ef-8549-8b7b0ebe6b68" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CurrentTaxLiabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TaxLiabilities_019e640b-7266-700e-a58c-69b572b150b0" xlink:to="loc_ifrs-full_CurrentTaxLiabilities_019e640b-7266-72ef-8549-8b7b0ebe6b68" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DeferredTaxLiabilities_019e640b-7266-74bb-a655-e2e89134ea5a" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DeferredTaxLiabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TaxLiabilities_019e640b-7266-700e-a58c-69b572b150b0" xlink:to="loc_ifrs-full_DeferredTaxLiabilities_019e640b-7266-74bb-a655-e2e89134ea5a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Equity_019e640b-7266-7303-8ed3-a9ae2f1276e2" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Equity"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-73ac-b706-5cf5d1a07f0f" xlink:href="san-20260630.xsd#san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_019e640b-7266-7303-8ed3-a9ae2f1276e2" xlink:to="loc_san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-73ac-b706-5cf5d1a07f0f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AccumulatedOtherComprehensiveIncome_019e640b-7266-7aa3-86a9-4f2b5b906d4c" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AccumulatedOtherComprehensiveIncome"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_019e640b-7266-7303-8ed3-a9ae2f1276e2" xlink:to="loc_ifrs-full_AccumulatedOtherComprehensiveIncome_019e640b-7266-7aa3-86a9-4f2b5b906d4c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncontrollingInterests_019e640b-7266-7d1c-9ddd-6c170839c091" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_NoncontrollingInterests"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_019e640b-7266-7303-8ed3-a9ae2f1276e2" xlink:to="loc_ifrs-full_NoncontrollingInterests_019e640b-7266-7d1c-9ddd-6c170839c091" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-7dd0-8670-afd609853d52" xlink:href="san-20260630.xsd#san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_RevaluationSurplus_019e640b-7266-701f-9184-66bf83d5eec9" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_RevaluationSurplus"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-7dd0-8670-afd609853d52" xlink:to="loc_ifrs-full_RevaluationSurplus_019e640b-7266-701f-9184-66bf83d5eec9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ProfitLossAttributableToShareholdersOfParent_019e640b-7266-7a30-b1a0-44258850ccd9" xlink:href="san-20260630.xsd#san_ProfitLossAttributableToShareholdersOfParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-7dd0-8670-afd609853d52" xlink:to="loc_san_ProfitLossAttributableToShareholdersOfParent_019e640b-7266-7a30-b1a0-44258850ccd9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_SharePremium_019e640b-7266-7fba-9de7-d611f8063853" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_SharePremium"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-7dd0-8670-afd609853d52" xlink:to="loc_ifrs-full_SharePremium_019e640b-7266-7fba-9de7-d611f8063853" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReserveOfEquityComponentOfConvertibleInstruments_019e640b-7266-7e37-a7ce-926a24ed7475" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReserveOfEquityComponentOfConvertibleInstruments"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-7dd0-8670-afd609853d52" xlink:to="loc_ifrs-full_ReserveOfEquityComponentOfConvertibleInstruments_019e640b-7266-7e37-a7ce-926a24ed7475" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_RetainedEarningsExcludingProfitLossForReportingPeriod_019e640b-7266-71b9-bb83-b717c50404ee" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_RetainedEarningsExcludingProfitLossForReportingPeriod"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-7dd0-8670-afd609853d52" xlink:to="loc_ifrs-full_RetainedEarningsExcludingProfitLossForReportingPeriod_019e640b-7266-71b9-bb83-b717c50404ee" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_TreasuryShares_019e640b-7266-766d-ba9a-a1aa31383fd0" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_TreasuryShares"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-7dd0-8670-afd609853d52" xlink:to="loc_ifrs-full_TreasuryShares_019e640b-7266-766d-ba9a-a1aa31383fd0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherReserves_019e640b-7266-76c7-8281-df06067f7abd" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherReserves"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-7dd0-8670-afd609853d52" xlink:to="loc_ifrs-full_OtherReserves_019e640b-7266-76c7-8281-df06067f7abd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherEquityInterest_019e640b-7266-74a5-9037-3fb960c3dba3" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherEquityInterest"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-7dd0-8670-afd609853d52" xlink:to="loc_ifrs-full_OtherEquityInterest_019e640b-7266-74a5-9037-3fb960c3dba3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IssuedCapital_019e640b-7266-7fa8-bb87-db4c3790b766" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IssuedCapital"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-7dd0-8670-afd609853d52" xlink:to="loc_ifrs-full_IssuedCapital_019e640b-7266-7fa8-bb87-db4c3790b766" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_InterimDividends_019e640b-7266-73cc-849d-55b07be7a28b" xlink:href="san-20260630.xsd#san_InterimDividends"/>
    <link:calculationArc order="10" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_EquityAttributableToOwnersOfParentExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-7dd0-8670-afd609853d52" xlink:to="loc_san_InterimDividends_019e640b-7266-73cc-849d-55b07be7a28b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Liabilities_019e640b-7266-7cb7-99f7-f9c3b3e586ee" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Liabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinancialLiabilitiesAtFairValueThroughProfitOrLossClassifiedAsHeldForTrading_019e640b-7266-75ea-b11c-9c25b46f522e" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FinancialLiabilitiesAtFairValueThroughProfitOrLossClassifiedAsHeldForTrading"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Liabilities_019e640b-7266-7cb7-99f7-f9c3b3e586ee" xlink:to="loc_ifrs-full_FinancialLiabilitiesAtFairValueThroughProfitOrLossClassifiedAsHeldForTrading_019e640b-7266-75ea-b11c-9c25b46f522e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinancialLiabilitiesAtFairValueThroughProfitOrLossDesignatedAsUponInitialRecognition_019e640b-7266-7473-9469-1b1719b4c75a" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FinancialLiabilitiesAtFairValueThroughProfitOrLossDesignatedAsUponInitialRecognition"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Liabilities_019e640b-7266-7cb7-99f7-f9c3b3e586ee" xlink:to="loc_ifrs-full_FinancialLiabilitiesAtFairValueThroughProfitOrLossDesignatedAsUponInitialRecognition_019e640b-7266-7473-9469-1b1719b4c75a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinancialLiabilitiesAtAmortisedCost_019e640b-7266-7541-ad7d-408f7548297f" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FinancialLiabilitiesAtAmortisedCost"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Liabilities_019e640b-7266-7cb7-99f7-f9c3b3e586ee" xlink:to="loc_ifrs-full_FinancialLiabilitiesAtAmortisedCost_019e640b-7266-7541-ad7d-408f7548297f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DerivativeFinancialLiabilitiesHeldForHedging_019e640b-7266-7def-bb1d-1c9734b533bf" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DerivativeFinancialLiabilitiesHeldForHedging"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Liabilities_019e640b-7266-7cb7-99f7-f9c3b3e586ee" xlink:to="loc_ifrs-full_DerivativeFinancialLiabilitiesHeldForHedging_019e640b-7266-7def-bb1d-1c9734b533bf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AccumulatedFairValueHedgeAdjustmentOnHedgedItemIncludedInCarryingAmountLiabilities_019e640b-7266-7e49-b35d-68e1b01a55c0" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AccumulatedFairValueHedgeAdjustmentOnHedgedItemIncludedInCarryingAmountLiabilities"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Liabilities_019e640b-7266-7cb7-99f7-f9c3b3e586ee" xlink:to="loc_ifrs-full_AccumulatedFairValueHedgeAdjustmentOnHedgedItemIncludedInCarryingAmountLiabilities_019e640b-7266-7e49-b35d-68e1b01a55c0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Provisions_019e640b-7266-74a6-9afc-126903dbefa2" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Provisions"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Liabilities_019e640b-7266-7cb7-99f7-f9c3b3e586ee" xlink:to="loc_ifrs-full_Provisions_019e640b-7266-74a6-9afc-126903dbefa2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_TaxLiabilities_019e640b-7266-70d1-bdc9-e83d4a29ce85" xlink:href="san-20260630.xsd#san_TaxLiabilities"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Liabilities_019e640b-7266-7cb7-99f7-f9c3b3e586ee" xlink:to="loc_san_TaxLiabilities_019e640b-7266-70d1-bdc9-e83d4a29ce85" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherLiabilities_019e640b-7266-7477-82fe-e49203d0b57c" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherLiabilities"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Liabilities_019e640b-7266-7cb7-99f7-f9c3b3e586ee" xlink:to="loc_ifrs-full_OtherLiabilities_019e640b-7266-7477-82fe-e49203d0b57c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_LiabilitiesIncludedInDisposalGroupsClassifiedAsHeldForSale_019e640b-7266-7069-b8be-9f7755616beb" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_LiabilitiesIncludedInDisposalGroupsClassifiedAsHeldForSale"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Liabilities_019e640b-7266-7cb7-99f7-f9c3b3e586ee" xlink:to="loc_ifrs-full_LiabilitiesIncludedInDisposalGroupsClassifiedAsHeldForSale_019e640b-7266-7069-b8be-9f7755616beb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InsuranceContractsIssuedThatAreLiabilities_019e640b-7266-7d8f-9a84-53854dcae3cd" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InsuranceContractsIssuedThatAreLiabilities"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Liabilities_019e640b-7266-7cb7-99f7-f9c3b3e586ee" xlink:to="loc_ifrs-full_InsuranceContractsIssuedThatAreLiabilities_019e640b-7266-7d8f-9a84-53854dcae3cd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_TaxAssets_019e640b-7266-742c-9d66-b3b626d9c0ff" xlink:href="san-20260630.xsd#san_TaxAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CurrentTaxAssets_019e640b-7266-73bb-9164-f860e9638bb2" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CurrentTaxAssets"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TaxAssets_019e640b-7266-742c-9d66-b3b626d9c0ff" xlink:to="loc_ifrs-full_CurrentTaxAssets_019e640b-7266-73bb-9164-f860e9638bb2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DeferredTaxAssets_019e640b-7266-73dc-8233-ec91fb4f844a" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DeferredTaxAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TaxAssets_019e640b-7266-742c-9d66-b3b626d9c0ff" xlink:to="loc_ifrs-full_DeferredTaxAssets_019e640b-7266-73dc-8233-ec91fb4f844a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_EquityAndLiabilities_019e640b-7266-7cb1-93be-362faf776779" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_EquityAndLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Liabilities_019e640b-7266-7cc2-a46f-388e71563817" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Liabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_EquityAndLiabilities_019e640b-7266-7cb1-93be-362faf776779" xlink:to="loc_ifrs-full_Liabilities_019e640b-7266-7cc2-a46f-388e71563817" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Equity_019e640b-7266-7ef2-8804-06a938e82932" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Equity"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_EquityAndLiabilities_019e640b-7266-7cb1-93be-362faf776779" xlink:to="loc_ifrs-full_Equity_019e640b-7266-7ef2-8804-06a938e82932" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReserveOfEquityComponentOfConvertibleInstruments_019e640b-7266-7f99-a463-f9d72a4eba53" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReserveOfEquityComponentOfConvertibleInstruments"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_CompoundFinancialInstrumentEquityComponent_019e640b-7266-742b-bc36-1d3612029e12" xlink:href="san-20260630.xsd#san_CompoundFinancialInstrumentEquityComponent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ReserveOfEquityComponentOfConvertibleInstruments_019e640b-7266-7f99-a463-f9d72a4eba53" xlink:to="loc_san_CompoundFinancialInstrumentEquityComponent_019e640b-7266-742b-bc36-1d3612029e12" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherEquityInstrumentsIssued_019e640b-7266-791a-8707-65a2d2eea5af" xlink:href="san-20260630.xsd#san_OtherEquityInstrumentsIssued"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ReserveOfEquityComponentOfConvertibleInstruments_019e640b-7266-7f99-a463-f9d72a4eba53" xlink:to="loc_san_OtherEquityInstrumentsIssued_019e640b-7266-791a-8707-65a2d2eea5af" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashAndCashEquivalents_019e640b-7266-71ee-b1b7-b30f6bb56253" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashAndCashEquivalents"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_ifrs-full_CashAndCashEquivalents_019e640b-7266-71ee-b1b7-b30f6bb56253" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossClassifiedAsHeldForTrading_019e640b-7266-79ff-8b17-8460486be389" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossClassifiedAsHeldForTrading"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossClassifiedAsHeldForTrading_019e640b-7266-79ff-8b17-8460486be389" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossMandatorilyMeasuredAtFairValue_019e640b-7266-7792-b95a-bb253c95ffe6" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossMandatorilyMeasuredAtFairValue"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossMandatorilyMeasuredAtFairValue_019e640b-7266-7792-b95a-bb253c95ffe6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossDesignatedAsUponInitialRecognition_019e640b-7266-7e6a-a9d4-105b8f0ae7d3" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossDesignatedAsUponInitialRecognition"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossDesignatedAsUponInitialRecognition_019e640b-7266-7e6a-a9d4-105b8f0ae7d3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinancialAssetsAtFairValueThroughOtherComprehensiveIncome_019e640b-7266-78ef-9fcf-b6080a74f422" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FinancialAssetsAtFairValueThroughOtherComprehensiveIncome"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_ifrs-full_FinancialAssetsAtFairValueThroughOtherComprehensiveIncome_019e640b-7266-78ef-9fcf-b6080a74f422" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinancialAssetsAtAmortisedCost_019e640b-7266-7e15-a5a8-435482c49b5c" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FinancialAssetsAtAmortisedCost"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_ifrs-full_FinancialAssetsAtAmortisedCost_019e640b-7266-7e15-a5a8-435482c49b5c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DerivativeFinancialAssetsHeldForHedging_019e640b-7266-7981-b82f-82ebbe4b31bb" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DerivativeFinancialAssetsHeldForHedging"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_ifrs-full_DerivativeFinancialAssetsHeldForHedging_019e640b-7266-7981-b82f-82ebbe4b31bb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AccumulatedFairValueHedgeAdjustmentOnHedgedItemIncludedInCarryingAmountAssets_019e640b-7266-7c36-b38e-9664f4c29156" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AccumulatedFairValueHedgeAdjustmentOnHedgedItemIncludedInCarryingAmountAssets"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_ifrs-full_AccumulatedFairValueHedgeAdjustmentOnHedgedItemIncludedInCarryingAmountAssets_019e640b-7266-7c36-b38e-9664f4c29156" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InvestmentAccountedForUsingEquityMethod_019e640b-7266-7025-9560-25079b22c721" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InvestmentAccountedForUsingEquityMethod"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_ifrs-full_InvestmentAccountedForUsingEquityMethod_019e640b-7266-7025-9560-25079b22c721" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReinsuranceContractsHeldThatAreAssets_019e640b-7266-77ed-9ab5-c829d92fad29" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReinsuranceContractsHeldThatAreAssets"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_ifrs-full_ReinsuranceContractsHeldThatAreAssets_019e640b-7266-77ed-9ab5-c829d92fad29" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_TangibleAssets_019e640b-7266-78c5-be34-12f3678889c9" xlink:href="san-20260630.xsd#san_TangibleAssets"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_san_TangibleAssets_019e640b-7266-78c5-be34-12f3678889c9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IntangibleAssetsAndGoodwill_019e640b-7266-787a-8fa2-1f5bdc6795f3" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IntangibleAssetsAndGoodwill"/>
    <link:calculationArc order="12" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_ifrs-full_IntangibleAssetsAndGoodwill_019e640b-7266-787a-8fa2-1f5bdc6795f3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_TaxAssets_019e640b-7266-7221-8f45-96b174fedbc3" xlink:href="san-20260630.xsd#san_TaxAssets"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_san_TaxAssets_019e640b-7266-7221-8f45-96b174fedbc3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherAssets_019e640b-7266-7084-8f26-601d01c7ddbc" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherAssets"/>
    <link:calculationArc order="14" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_ifrs-full_OtherAssets_019e640b-7266-7084-8f26-601d01c7ddbc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncurrentAssetsOrDisposalGroupsClassifiedAsHeldForSale_019e640b-7266-7cb6-9a5c-d84bd1169b39" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_NoncurrentAssetsOrDisposalGroupsClassifiedAsHeldForSale"/>
    <link:calculationArc order="15" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7266-73f5-8d87-c699ae10a824" xlink:to="loc_ifrs-full_NoncurrentAssetsOrDisposalGroupsClassifiedAsHeldForSale_019e640b-7266-7cb6-9a5c-d84bd1169b39" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AccumulatedOtherComprehensiveIncome_019e640b-7266-77b9-92f5-c8a50867ef35" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AccumulatedOtherComprehensiveIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss_019e640b-7266-7b97-baa5-5a6357c26ebb" xlink:href="san-20260630.xsd#san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AccumulatedOtherComprehensiveIncome_019e640b-7266-77b9-92f5-c8a50867ef35" xlink:to="loc_san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss_019e640b-7266-7b97-baa5-5a6357c26ebb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherComprehensiveIncomeItemsThatMayBeReclassifiedToProfitOrLoss_019e640b-7266-7bda-be4d-62e12072cf29" xlink:href="san-20260630.xsd#san_OtherComprehensiveIncomeItemsThatMayBeReclassifiedToProfitOrLoss"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AccumulatedOtherComprehensiveIncome_019e640b-7266-77b9-92f5-c8a50867ef35" xlink:to="loc_san_OtherComprehensiveIncomeItemsThatMayBeReclassifiedToProfitOrLoss_019e640b-7266-7bda-be4d-62e12072cf29" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InvestmentAccountedForUsingEquityMethod_019e640b-7266-7077-b43a-86b86a02d969" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InvestmentAccountedForUsingEquityMethod"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InvestmentsInJointVenturesAccountedForUsingEquityMethod_019e640b-7266-70e5-a2b8-bc56221b0862" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InvestmentsInJointVenturesAccountedForUsingEquityMethod"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_InvestmentAccountedForUsingEquityMethod_019e640b-7266-7077-b43a-86b86a02d969" xlink:to="loc_ifrs-full_InvestmentsInJointVenturesAccountedForUsingEquityMethod_019e640b-7266-70e5-a2b8-bc56221b0862" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InvestmentsInAssociatesAccountedForUsingEquityMethod_019e640b-7266-7371-83b2-918216eb2c42" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InvestmentsInAssociatesAccountedForUsingEquityMethod"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_InvestmentAccountedForUsingEquityMethod_019e640b-7266-7077-b43a-86b86a02d969" xlink:to="loc_ifrs-full_InvestmentsInAssociatesAccountedForUsingEquityMethod_019e640b-7266-7371-83b2-918216eb2c42" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IssuedCapital_019e640b-7266-72e5-87a9-16ffe149d2d9" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IssuedCapital"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_CalledUpPaidCapital_019e640b-7266-74d2-8758-20a91777365f" xlink:href="san-20260630.xsd#san_CalledUpPaidCapital"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_IssuedCapital_019e640b-7266-72e5-87a9-16ffe149d2d9" xlink:to="loc_san_CalledUpPaidCapital_019e640b-7266-74d2-8758-20a91777365f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_UnpaidCapitalCalledUp_019e640b-7266-7de3-a2ce-45c0aaf85d08" xlink:href="san-20260630.xsd#san_UnpaidCapitalCalledUp"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_IssuedCapital_019e640b-7266-72e5-87a9-16ffe149d2d9" xlink:to="loc_san_UnpaidCapitalCalledUp_019e640b-7266-7de3-a2ce-45c0aaf85d08" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IntangibleAssetsAndGoodwill_019e640b-7266-7c9f-8ccb-07e9357ae6ed" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IntangibleAssetsAndGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Goodwill_019e640b-7266-7591-be70-97743b907dbe" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Goodwill"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_IntangibleAssetsAndGoodwill_019e640b-7266-7c9f-8ccb-07e9357ae6ed" xlink:to="loc_ifrs-full_Goodwill_019e640b-7266-7591-be70-97743b907dbe" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IntangibleAssetsOtherThanGoodwill_019e640b-7266-787b-80df-cf5a5724068a" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IntangibleAssetsOtherThanGoodwill"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_IntangibleAssetsAndGoodwill_019e640b-7266-7c9f-8ccb-07e9357ae6ed" xlink:to="loc_ifrs-full_IntangibleAssetsOtherThanGoodwill_019e640b-7266-787b-80df-cf5a5724068a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_TangibleAssets_019e640b-7266-718f-8526-1097315498d1" xlink:href="san-20260630.xsd#san_TangibleAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PropertyPlantAndEquipmentIncludingRightofuseAssets_019e640b-7266-7a12-8c9c-0653e918f6d7" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_PropertyPlantAndEquipmentIncludingRightofuseAssets"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TangibleAssets_019e640b-7266-718f-8526-1097315498d1" xlink:to="loc_ifrs-full_PropertyPlantAndEquipmentIncludingRightofuseAssets_019e640b-7266-7a12-8c9c-0653e918f6d7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InvestmentProperty_019e640b-7266-7406-954c-900fb892e4fa" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InvestmentProperty"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TangibleAssets_019e640b-7266-718f-8526-1097315498d1" xlink:to="loc_ifrs-full_InvestmentProperty_019e640b-7266-7406-954c-900fb892e4fa" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherAssets_019e640b-7266-71d3-b72d-e61d9cb1062d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InsuranceContractsIssuedThatAreAssets_019e640b-7266-70a5-b4f1-81e7b2011d71" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InsuranceContractsIssuedThatAreAssets"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherAssets_019e640b-7266-71d3-b72d-e61d9cb1062d" xlink:to="loc_ifrs-full_InsuranceContractsIssuedThatAreAssets_019e640b-7266-70a5-b4f1-81e7b2011d71" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Inventories_019e640b-7266-7930-95b6-20d742033fe3" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Inventories"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherAssets_019e640b-7266-71d3-b72d-e61d9cb1062d" xlink:to="loc_ifrs-full_Inventories_019e640b-7266-7930-95b6-20d742033fe3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherNonfinancialAssets_019e640b-7266-78bc-840a-9b6ea21867c9" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherNonfinancialAssets"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherAssets_019e640b-7266-71d3-b72d-e61d9cb1062d" xlink:to="loc_ifrs-full_OtherNonfinancialAssets_019e640b-7266-78bc-840a-9b6ea21867c9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_NoncontrollingInterests_019e640b-7266-7b2c-b178-b0b31e11ad69" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_NoncontrollingInterests"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_AccumulatedOtherComprehensiveIncomeAttributableToNonControllingInterests_019e640b-7266-76fd-9a6e-6bed443ebc73" xlink:href="san-20260630.xsd#san_AccumulatedOtherComprehensiveIncomeAttributableToNonControllingInterests"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncontrollingInterests_019e640b-7266-7b2c-b178-b0b31e11ad69" xlink:to="loc_san_AccumulatedOtherComprehensiveIncomeAttributableToNonControllingInterests_019e640b-7266-76fd-9a6e-6bed443ebc73" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_NonControllingInterestExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-721f-b635-710f94aac754" xlink:href="san-20260630.xsd#san_NonControllingInterestExcludingAccumulatedOtherComprehensiveIncome"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_NoncontrollingInterests_019e640b-7266-7b2c-b178-b0b31e11ad69" xlink:to="loc_san_NonControllingInterestExcludingAccumulatedOtherComprehensiveIncome_019e640b-7266-721f-b635-710f94aac754" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/CondensedConsolidatedIncomeStatements" xlink:type="simple" xlink:href="san-20260630.xsd#CondensedConsolidatedIncomeStatements"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/CondensedConsolidatedIncomeStatements" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InterestRevenueExpense_019e640b-7266-73a7-b17a-e83c5cc0fc92" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InterestRevenueExpense"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_RevenueFromInterest_019e640b-7266-753f-9882-6f2ec0c913e4" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_RevenueFromInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_InterestRevenueExpense_019e640b-7266-73a7-b17a-e83c5cc0fc92" xlink:to="loc_ifrs-full_RevenueFromInterest_019e640b-7266-753f-9882-6f2ec0c913e4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InterestExpense_019e640b-7266-7f54-8208-aff3ddd9fdd8" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InterestExpense"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_InterestRevenueExpense_019e640b-7266-73a7-b17a-e83c5cc0fc92" xlink:to="loc_ifrs-full_InterestExpense_019e640b-7266-7f54-8208-aff3ddd9fdd8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7266-75ea-ac7d-7d42d38895c7" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLossBeforeTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ImpairmentLossReversalOfImpairmentOfInvestmentsInSubsidiariesJointVenturesAndAssociatesNet_019e640b-7266-7166-90e6-6989728dea06" xlink:href="san-20260630.xsd#san_ImpairmentLossReversalOfImpairmentOfInvestmentsInSubsidiariesJointVenturesAndAssociatesNet"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7266-75ea-ac7d-7d42d38895c7" xlink:to="loc_san_ImpairmentLossReversalOfImpairmentOfInvestmentsInSubsidiariesJointVenturesAndAssociatesNet_019e640b-7266-7166-90e6-6989728dea06" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GrossProfit_019e640b-7266-781f-8adc-2d7573e73bad" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_GrossProfit"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7266-75ea-ac7d-7d42d38895c7" xlink:to="loc_ifrs-full_GrossProfit_019e640b-7266-781f-8adc-2d7573e73bad" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DepreciationAndAmortisationExpense_019e640b-7266-71c3-ab23-7c98ce2e1383" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DepreciationAndAmortisationExpense"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7266-75ea-ac7d-7d42d38895c7" xlink:to="loc_ifrs-full_DepreciationAndAmortisationExpense_019e640b-7266-71c3-ab23-7c98ce2e1383" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_GainsLossesOnDisposalsOfNonFinancialAssetsNet_019e640b-7266-78e8-bc56-401031aa81e7" xlink:href="san-20260630.xsd#san_GainsLossesOnDisposalsOfNonFinancialAssetsNet"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7266-75ea-ac7d-7d42d38895c7" xlink:to="loc_san_GainsLossesOnDisposalsOfNonFinancialAssetsNet_019e640b-7266-78e8-bc56-401031aa81e7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_GainsLossesOnNoncurrentAssetsHeldForSaleNotClassifiedAsDiscontinuedOperations_019e640b-7266-7766-95fb-3f02176cd7d7" xlink:href="san-20260630.xsd#san_GainsLossesOnNoncurrentAssetsHeldForSaleNotClassifiedAsDiscontinuedOperations"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7266-75ea-ac7d-7d42d38895c7" xlink:to="loc_san_GainsLossesOnNoncurrentAssetsHeldForSaleNotClassifiedAsDiscontinuedOperations_019e640b-7266-7766-95fb-3f02176cd7d7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ProvisionsAndReversalOfProvisions_019e640b-7266-7dd9-8657-574e9f1ad917" xlink:href="san-20260630.xsd#san_ProvisionsAndReversalOfProvisions"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7266-75ea-ac7d-7d42d38895c7" xlink:to="loc_san_ProvisionsAndReversalOfProvisions_019e640b-7266-7dd9-8657-574e9f1ad917" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ImpairmentLossReversalOfImpairmentRecognisedInProfitOrLossNonFinancialAssetsNet_019e640b-7266-7cda-9a7f-d24baff06f81" xlink:href="san-20260630.xsd#san_ImpairmentLossReversalOfImpairmentRecognisedInProfitOrLossNonFinancialAssetsNet"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7266-75ea-ac7d-7d42d38895c7" xlink:to="loc_san_ImpairmentLossReversalOfImpairmentRecognisedInProfitOrLossNonFinancialAssetsNet_019e640b-7266-7cda-9a7f-d24baff06f81" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ImpairmentLossImpairmentGainAndReversalOfImpairmentLossDeterminedInAccordanceWithIFRS9_019e640b-7266-7162-aead-feccdf2e55cc" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ImpairmentLossImpairmentGainAndReversalOfImpairmentLossDeterminedInAccordanceWithIFRS9"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7266-75ea-ac7d-7d42d38895c7" xlink:to="loc_ifrs-full_ImpairmentLossImpairmentGainAndReversalOfImpairmentLossDeterminedInAccordanceWithIFRS9_019e640b-7266-7162-aead-feccdf2e55cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdministrativeExpense_019e640b-7266-7481-a41a-c35d9618716e" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdministrativeExpense"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7266-75ea-ac7d-7d42d38895c7" xlink:to="loc_ifrs-full_AdministrativeExpense_019e640b-7266-7481-a41a-c35d9618716e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GainRecognisedInBargainPurchaseTransaction_019e640b-7266-7675-a374-bdd1e5f5bfdd" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_GainRecognisedInBargainPurchaseTransaction"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7266-75ea-ac7d-7d42d38895c7" xlink:to="loc_ifrs-full_GainRecognisedInBargainPurchaseTransaction_019e640b-7266-7675-a374-bdd1e5f5bfdd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_GrossProfit"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FeeAndCommissionIncome_019e640b-7266-74db-b3c4-353aac27fe94" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FeeAndCommissionIncome"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_ifrs-full_FeeAndCommissionIncome_019e640b-7266-74db-b3c4-353aac27fe94" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_GainsLossesOnFinancialAssetsAndLiabilitiesAtFairValueThroughProfitOrLoss_019e640b-7266-7d69-8ca4-ac31c1771289" xlink:href="san-20260630.xsd#san_GainsLossesOnFinancialAssetsAndLiabilitiesAtFairValueThroughProfitOrLoss"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_san_GainsLossesOnFinancialAssetsAndLiabilitiesAtFairValueThroughProfitOrLoss_019e640b-7266-7d69-8ca4-ac31c1771289" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GainsLossesOnFinancialAssetsAtFairValueThroughProfitOrLossMandatorilyMeasuredAtFairValue_019e640b-7266-7619-a9ed-75a2c14d3599" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_GainsLossesOnFinancialAssetsAtFairValueThroughProfitOrLossMandatorilyMeasuredAtFairValue"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_ifrs-full_GainsLossesOnFinancialAssetsAtFairValueThroughProfitOrLossMandatorilyMeasuredAtFairValue_019e640b-7266-7619-a9ed-75a2c14d3599" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InterestRevenueExpense_019e640b-7266-7a90-b291-3ef9cecf48ae" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InterestRevenueExpense"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_ifrs-full_InterestRevenueExpense_019e640b-7266-7a90-b291-3ef9cecf48ae" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_GainsLossesOnFinancialAssetsAndLiabilitiesHeldForTrading_019e640b-7266-761b-b519-ddd28f394a73" xlink:href="san-20260630.xsd#san_GainsLossesOnFinancialAssetsAndLiabilitiesHeldForTrading"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_san_GainsLossesOnFinancialAssetsAndLiabilitiesHeldForTrading_019e640b-7266-761b-b519-ddd28f394a73" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FeeAndCommissionExpense_019e640b-7266-7b98-8619-de0c1c4fa7e3" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FeeAndCommissionExpense"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_ifrs-full_FeeAndCommissionExpense_019e640b-7266-7b98-8619-de0c1c4fa7e3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherOperatingExpense_019e640b-7266-7336-a6e1-a7b99d8fa859" xlink:href="san-20260630.xsd#san_OtherOperatingExpense"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_san_OtherOperatingExpense_019e640b-7266-7336-a6e1-a7b99d8fa859" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GainsLossesOnExchangeDifferencesOnTranslationRecognisedInProfitOrLoss_019e640b-7266-7ee5-8aae-9f228df57429" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_GainsLossesOnExchangeDifferencesOnTranslationRecognisedInProfitOrLoss"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_ifrs-full_GainsLossesOnExchangeDifferencesOnTranslationRecognisedInProfitOrLoss_019e640b-7266-7ee5-8aae-9f228df57429" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherOperatingIncome1_019e640b-7266-7b26-ab00-81ca8320243e" xlink:href="san-20260630.xsd#san_OtherOperatingIncome1"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_san_OtherOperatingIncome1_019e640b-7266-7b26-ab00-81ca8320243e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_RevenueFromDividends_019e640b-7266-72f7-b8c7-a2a78000cba0" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_RevenueFromDividends"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_ifrs-full_RevenueFromDividends_019e640b-7266-72f7-b8c7-a2a78000cba0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ExpensesFromInsuranceAndReinsuranceContractsRecognisedInProfitOrLoss_019e640b-7266-7ad3-b2d4-0d79018d3b27" xlink:href="san-20260630.xsd#san_ExpensesFromInsuranceAndReinsuranceContractsRecognisedInProfitOrLoss"/>
    <link:calculationArc order="11" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_san_ExpensesFromInsuranceAndReinsuranceContractsRecognisedInProfitOrLoss_019e640b-7266-7ad3-b2d4-0d79018d3b27" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_GainsLossesOnFinancialAssetsAndLiabilitiesNotMeasuredAtFairValueThroughProfitOrLossNet_019e640b-7266-7c4f-ae8a-50290f109bf5" xlink:href="san-20260630.xsd#san_GainsLossesOnFinancialAssetsAndLiabilitiesNotMeasuredAtFairValueThroughProfitOrLossNet"/>
    <link:calculationArc order="12" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_san_GainsLossesOnFinancialAssetsAndLiabilitiesNotMeasuredAtFairValueThroughProfitOrLossNet_019e640b-7266-7c4f-ae8a-50290f109bf5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_GainsOrLossesFromHedgeAccountingNet_019e640b-7266-7666-bd90-a6f75dcf197a" xlink:href="san-20260630.xsd#san_GainsOrLossesFromHedgeAccountingNet"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_san_GainsOrLossesFromHedgeAccountingNet_019e640b-7266-7666-bd90-a6f75dcf197a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod_019e640b-7266-7ec3-bce2-3e808fda4fa3" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod"/>
    <link:calculationArc order="14" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_ifrs-full_ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod_019e640b-7266-7ec3-bce2-3e808fda4fa3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_IncomeFromInsuranceAndReinsuranceContractsRecognisedInProfitOrLoss_019e640b-7266-7dd2-b1f9-6b829d100cd1" xlink:href="san-20260630.xsd#san_IncomeFromInsuranceAndReinsuranceContractsRecognisedInProfitOrLoss"/>
    <link:calculationArc order="15" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7266-7e7f-8d15-fb965155263c" xlink:to="loc_san_IncomeFromInsuranceAndReinsuranceContractsRecognisedInProfitOrLoss_019e640b-7266-7dd2-b1f9-6b829d100cd1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLoss_019e640b-7266-7521-bad3-91c35af58c23" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossFromDiscontinuedOperations_019e640b-7266-73fb-ae81-4fd84e7f0f0a" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLossFromDiscontinuedOperations"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLoss_019e640b-7266-7521-bad3-91c35af58c23" xlink:to="loc_ifrs-full_ProfitLossFromDiscontinuedOperations_019e640b-7266-73fb-ae81-4fd84e7f0f0a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossFromContinuingOperations_019e640b-7266-7159-b255-f3a93f6b7947" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLossFromContinuingOperations"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLoss_019e640b-7266-7521-bad3-91c35af58c23" xlink:to="loc_ifrs-full_ProfitLossFromContinuingOperations_019e640b-7266-7159-b255-f3a93f6b7947" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdministrativeExpense_019e640b-7266-7944-9f70-0bd42073e2a1" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdministrativeExpense"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_EmployeeBenefitsExpense_019e640b-7266-7a1b-a404-f9bd67c403a5" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_EmployeeBenefitsExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AdministrativeExpense_019e640b-7266-7944-9f70-0bd42073e2a1" xlink:to="loc_ifrs-full_EmployeeBenefitsExpense_019e640b-7266-7a1b-a404-f9bd67c403a5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherGeneralAdministrativeExpenses_019e640b-7266-7ef1-abf0-706c8efa9898" xlink:href="san-20260630.xsd#san_OtherGeneralAdministrativeExpenses"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AdministrativeExpense_019e640b-7266-7944-9f70-0bd42073e2a1" xlink:to="loc_san_OtherGeneralAdministrativeExpenses_019e640b-7266-7ef1-abf0-706c8efa9898" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossFromContinuingOperations_019e640b-7266-719f-853d-028482d6569e" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLossFromContinuingOperations"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncomeTaxExpenseContinuingOperations_019e640b-7266-70af-8718-9cc05aa403bd" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IncomeTaxExpenseContinuingOperations"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossFromContinuingOperations_019e640b-7266-719f-853d-028482d6569e" xlink:to="loc_ifrs-full_IncomeTaxExpenseContinuingOperations_019e640b-7266-70af-8718-9cc05aa403bd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7266-72a4-8f17-5e286b636783" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLossBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossFromContinuingOperations_019e640b-7266-719f-853d-028482d6569e" xlink:to="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7266-72a4-8f17-5e286b636783" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ImpairmentLossReversalOfImpairmentRecognisedInProfitOrLossNonFinancialAssetsNet_019e640b-7266-7299-b740-583913fdd3da" xlink:href="san-20260630.xsd#san_ImpairmentLossReversalOfImpairmentRecognisedInProfitOrLossNonFinancialAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ImpairmentLossOrReversalOfImpairmentRecognisedInProfitOrLossTangibleAssets_019e640b-7266-72c1-9b43-b0842bf63474" xlink:href="san-20260630.xsd#san_ImpairmentLossOrReversalOfImpairmentRecognisedInProfitOrLossTangibleAssets"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_ImpairmentLossReversalOfImpairmentRecognisedInProfitOrLossNonFinancialAssetsNet_019e640b-7266-7299-b740-583913fdd3da" xlink:to="loc_san_ImpairmentLossOrReversalOfImpairmentRecognisedInProfitOrLossTangibleAssets_019e640b-7266-72c1-9b43-b0842bf63474" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ImpairmentLossRecognisedInProfitOrLossIntangibleAssetsAndGoodwill_019e640b-7266-70d8-8f4a-19b40de83ae1" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ImpairmentLossRecognisedInProfitOrLossIntangibleAssetsAndGoodwill"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_ImpairmentLossReversalOfImpairmentRecognisedInProfitOrLossNonFinancialAssetsNet_019e640b-7266-7299-b740-583913fdd3da" xlink:to="loc_ifrs-full_ImpairmentLossRecognisedInProfitOrLossIntangibleAssetsAndGoodwill_019e640b-7266-70d8-8f4a-19b40de83ae1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ImpairmentLossOrReversalOfImpairmentRecognisedInProfitOrLossOtherNonFinancialAssetsNet_019e640b-7266-7d53-988e-3a07f412ca61" xlink:href="san-20260630.xsd#san_ImpairmentLossOrReversalOfImpairmentRecognisedInProfitOrLossOtherNonFinancialAssetsNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_ImpairmentLossReversalOfImpairmentRecognisedInProfitOrLossNonFinancialAssetsNet_019e640b-7266-7299-b740-583913fdd3da" xlink:to="loc_san_ImpairmentLossOrReversalOfImpairmentRecognisedInProfitOrLossOtherNonFinancialAssetsNet_019e640b-7266-7d53-988e-3a07f412ca61" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/CondensedConsolidatedIncomeStatements_1" xlink:type="simple" xlink:href="san-20260630.xsd#CondensedConsolidatedIncomeStatements_1"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/CondensedConsolidatedIncomeStatements_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLoss_019e640b-7266-7f5e-bbf2-3d31eca755d2" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossAttributableToOwnersOfParent_019e640b-7266-7254-8672-0864c54aa161" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLossAttributableToOwnersOfParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLoss_019e640b-7266-7f5e-bbf2-3d31eca755d2" xlink:to="loc_ifrs-full_ProfitLossAttributableToOwnersOfParent_019e640b-7266-7254-8672-0864c54aa161" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossAttributableToNoncontrollingInterests_019e640b-7266-7fbf-9af3-6344a745072e" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLossAttributableToNoncontrollingInterests"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLoss_019e640b-7266-7f5e-bbf2-3d31eca755d2" xlink:to="loc_ifrs-full_ProfitLossAttributableToNoncontrollingInterests_019e640b-7266-7fbf-9af3-6344a745072e" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/CondensedConsolidatedStatementsofRecognizedIncomeandExpense" xlink:type="simple" xlink:href="san-20260630.xsd#CondensedConsolidatedStatementsofRecognizedIncomeandExpense"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/CondensedConsolidatedStatementsofRecognizedIncomeandExpense" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019f8004-d1a7-75ff-8b7e-b48a3e8cc430" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans_019f8004-d1a7-74a4-a8c6-3519c4d3cdc1" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019f8004-d1a7-75ff-8b7e-b48a3e8cc430" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans_019f8004-d1a7-74a4-a8c6-3519c4d3cdc1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_NonCurrentAssetsHeldForSaleThatWillNotBeReclassifiedToProfitOrLossBeforeTax_019f8004-d1a7-7f4b-a270-08c53d3a46ea" xlink:href="san-20260630.xsd#san_NonCurrentAssetsHeldForSaleThatWillNotBeReclassifiedToProfitOrLossBeforeTax"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019f8004-d1a7-75ff-8b7e-b48a3e8cc430" xlink:to="loc_san_NonCurrentAssetsHeldForSaleThatWillNotBeReclassifiedToProfitOrLossBeforeTax_019f8004-d1a7-7f4b-a270-08c53d3a46ea" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ShareOfOtherComprehensiveIncomeOfAssociatesAndJointVenturesAccountedForUsingEquityMethodThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019f8004-d1a7-72ff-9bb4-425b67da36ba" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ShareOfOtherComprehensiveIncomeOfAssociatesAndJointVenturesAccountedForUsingEquityMethodThatWillNotBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019f8004-d1a7-75ff-8b7e-b48a3e8cc430" xlink:to="loc_ifrs-full_ShareOfOtherComprehensiveIncomeOfAssociatesAndJointVenturesAccountedForUsingEquityMethodThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019f8004-d1a7-72ff-9bb4-425b67da36ba" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesFromInvestmentsInEquityInstruments_019f8004-d1a7-720d-8c9c-bbaf5de64ec6" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesFromInvestmentsInEquityInstruments"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019f8004-d1a7-75ff-8b7e-b48a3e8cc430" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesFromInvestmentsInEquityInstruments_019f8004-d1a7-720d-8c9c-bbaf5de64ec6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnHedgingInstrumentsThatHedgeInvestmentsInEquityInstruments_019f8004-d1a7-70c0-a6f6-ad5a25a7504e" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnHedgingInstrumentsThatHedgeInvestmentsInEquityInstruments"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019f8004-d1a7-75ff-8b7e-b48a3e8cc430" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnHedgingInstrumentsThatHedgeInvestmentsInEquityInstruments_019f8004-d1a7-70c0-a6f6-ad5a25a7504e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ChangesInTheFairValueOfEquityInstrumentsMeasuredAtFairValueThroughOtherComprehensiveIncomeHedgedItem_019f8004-d1a7-7b71-aef0-604b7b87534d" xlink:href="san-20260630.xsd#san_ChangesInTheFairValueOfEquityInstrumentsMeasuredAtFairValueThroughOtherComprehensiveIncomeHedgedItem"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019f8004-d1a7-75ff-8b7e-b48a3e8cc430" xlink:to="loc_san_ChangesInTheFairValueOfEquityInstrumentsMeasuredAtFairValueThroughOtherComprehensiveIncomeHedgedItem_019f8004-d1a7-7b71-aef0-604b7b87534d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ChangesInTheFairValueOfEquityInstrumentsMeasuredAtFairValueThroughOtherComprehensiveIncomeHedgingInstrument_019f8004-d1a7-7b2b-992a-4f47305aeb43" xlink:href="san-20260630.xsd#san_ChangesInTheFairValueOfEquityInstrumentsMeasuredAtFairValueThroughOtherComprehensiveIncomeHedgingInstrument"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019f8004-d1a7-75ff-8b7e-b48a3e8cc430" xlink:to="loc_san_ChangesInTheFairValueOfEquityInstrumentsMeasuredAtFairValueThroughOtherComprehensiveIncomeHedgingInstrument_019f8004-d1a7-7b2b-992a-4f47305aeb43" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxChangeInFairValueOfFinancialLiabilityAttributableToChangeInCreditRiskOfLiability_019f8004-d1a7-72fd-9345-abfd69f8b13c" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxChangeInFairValueOfFinancialLiabilityAttributableToChangeInCreditRiskOfLiability"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019f8004-d1a7-75ff-8b7e-b48a3e8cc430" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxChangeInFairValueOfFinancialLiabilityAttributableToChangeInCreditRiskOfLiability_019f8004-d1a7-72fd-9345-abfd69f8b13c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLoss_019f8004-d1a7-76f7-9de5-4018b64a089e" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLoss"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019f8004-d1a7-75ff-8b7e-b48a3e8cc430" xlink:to="loc_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLoss_019f8004-d1a7-76f7-9de5-4018b64a089e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxExchangeDifferencesOnTranslation_019e640b-7266-7dc4-bb43-e896a900faf4" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxExchangeDifferencesOnTranslation"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GainsLossesOnExchangeDifferencesOnTranslationBeforeTax_019e640b-7266-78f2-be58-a184497829e3" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_GainsLossesOnExchangeDifferencesOnTranslationBeforeTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxExchangeDifferencesOnTranslation_019e640b-7266-7dc4-bb43-e896a900faf4" xlink:to="loc_ifrs-full_GainsLossesOnExchangeDifferencesOnTranslationBeforeTax_019e640b-7266-78f2-be58-a184497829e3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherReclassificationAdjustmentsOnExchangeDifferencesOnTranslationBeforeTax_019e640b-7266-77cd-91e7-5ff414877ef5" xlink:href="san-20260630.xsd#san_OtherReclassificationAdjustmentsOnExchangeDifferencesOnTranslationBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxExchangeDifferencesOnTranslation_019e640b-7266-7dc4-bb43-e896a900faf4" xlink:to="loc_san_OtherReclassificationAdjustmentsOnExchangeDifferencesOnTranslationBeforeTax_019e640b-7266-77cd-91e7-5ff414877ef5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReclassificationAdjustmentsOnExchangeDifferencesOnTranslationBeforeTax_019e640b-7266-7e3e-a65d-567940cf80bc" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReclassificationAdjustmentsOnExchangeDifferencesOnTranslationBeforeTax"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxExchangeDifferencesOnTranslation_019e640b-7266-7dc4-bb43-e896a900faf4" xlink:to="loc_ifrs-full_ReclassificationAdjustmentsOnExchangeDifferencesOnTranslationBeforeTax_019e640b-7266-7e3e-a65d-567940cf80bc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_019f8003-c1c2-76b1-a731-9f5d2fdd5b53" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxHedgesOfNetInvestmentsInForeignOperations_019f8003-c1c2-768f-8ab1-ab4c38c4a069" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxHedgesOfNetInvestmentsInForeignOperations"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_019f8003-c1c2-76b1-a731-9f5d2fdd5b53" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxHedgesOfNetInvestmentsInForeignOperations_019f8003-c1c2-768f-8ab1-ab4c38c4a069" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxExchangeDifferencesOnTranslation_019f8003-c1c2-721f-b14a-2bde16473fe2" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxExchangeDifferencesOnTranslation"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_019f8003-c1c2-76b1-a731-9f5d2fdd5b53" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxExchangeDifferencesOnTranslation_019f8003-c1c2-721f-b14a-2bde16473fe2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxCashFlowHedges_019f8003-c1c2-74e2-a504-bd3156387f6f" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxCashFlowHedges"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_019f8003-c1c2-76b1-a731-9f5d2fdd5b53" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxCashFlowHedges_019f8003-c1c2-74e2-a504-bd3156387f6f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherComprehensiveIncomeBeforeTaxHedgingInstrumentsNotDesignated_019f8003-c1c2-7d37-ab42-38ac8cbfee49" xlink:href="san-20260630.xsd#san_OtherComprehensiveIncomeBeforeTaxHedgingInstrumentsNotDesignated"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_019f8003-c1c2-76b1-a731-9f5d2fdd5b53" xlink:to="loc_san_OtherComprehensiveIncomeBeforeTaxHedgingInstrumentsNotDesignated_019f8003-c1c2-7d37-ab42-38ac8cbfee49" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome_019f8003-c1c2-756c-b3b5-8f123745f730" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_019f8003-c1c2-76b1-a731-9f5d2fdd5b53" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome_019f8003-c1c2-756c-b3b5-8f123745f730" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherComprehensiveIncomeBeforeTaxNonCurrentAssetsClassifiedAsHeldForSale_019f8003-c1c2-7fae-be80-ba7c02f60f25" xlink:href="san-20260630.xsd#san_OtherComprehensiveIncomeBeforeTaxNonCurrentAssetsClassifiedAsHeldForSale"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_019f8003-c1c2-76b1-a731-9f5d2fdd5b53" xlink:to="loc_san_OtherComprehensiveIncomeBeforeTaxNonCurrentAssetsClassifiedAsHeldForSale_019f8003-c1c2-7fae-be80-ba7c02f60f25" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ShareOfOtherComprehensiveIncomeOfAssociatesAndJointVenturesAccountedForUsingEquityMethodThatWillBeReclassifiedToProfitOrLossNetOfTax_019f8003-c1c2-78b3-bb4b-8422baff6d4c" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ShareOfOtherComprehensiveIncomeOfAssociatesAndJointVenturesAccountedForUsingEquityMethodThatWillBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_019f8003-c1c2-76b1-a731-9f5d2fdd5b53" xlink:to="loc_ifrs-full_ShareOfOtherComprehensiveIncomeOfAssociatesAndJointVenturesAccountedForUsingEquityMethodThatWillBeReclassifiedToProfitOrLossNetOfTax_019f8003-c1c2-78b3-bb4b-8422baff6d4c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLoss_019f8003-c1c2-707f-8927-9d78b5ff32c4" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLoss"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_019f8003-c1c2-76b1-a731-9f5d2fdd5b53" xlink:to="loc_ifrs-full_IncomeTaxRelatingToComponentsOfOtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLoss_019f8003-c1c2-707f-8927-9d78b5ff32c4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxHedgesOfNetInvestmentsInForeignOperations_019e640b-7266-723e-b4f2-9b2623cbbaa4" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxHedgesOfNetInvestmentsInForeignOperations"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherReclassificationAdjustmentsOnHedgesOfNetInvestmentsInForeignOperationsBeforeTax_019e640b-7266-76d2-bfc9-29e4f3bffe84" xlink:href="san-20260630.xsd#san_OtherReclassificationAdjustmentsOnHedgesOfNetInvestmentsInForeignOperationsBeforeTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxHedgesOfNetInvestmentsInForeignOperations_019e640b-7266-723e-b4f2-9b2623cbbaa4" xlink:to="loc_san_OtherReclassificationAdjustmentsOnHedgesOfNetInvestmentsInForeignOperationsBeforeTax_019e640b-7266-76d2-bfc9-29e4f3bffe84" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReclassificationAdjustmentsOnHedgesOfNetInvestmentsInForeignOperationsBeforeTax_019e640b-7266-7759-8c37-a30ac773f3a5" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReclassificationAdjustmentsOnHedgesOfNetInvestmentsInForeignOperationsBeforeTax"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxHedgesOfNetInvestmentsInForeignOperations_019e640b-7266-723e-b4f2-9b2623cbbaa4" xlink:to="loc_ifrs-full_ReclassificationAdjustmentsOnHedgesOfNetInvestmentsInForeignOperationsBeforeTax_019e640b-7266-7759-8c37-a30ac773f3a5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GainsLossesOnHedgesOfNetInvestmentsInForeignOperationsBeforeTax_019e640b-7266-7b8f-a254-ee53332920f7" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_GainsLossesOnHedgesOfNetInvestmentsInForeignOperationsBeforeTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxHedgesOfNetInvestmentsInForeignOperations_019e640b-7266-723e-b4f2-9b2623cbbaa4" xlink:to="loc_ifrs-full_GainsLossesOnHedgesOfNetInvestmentsInForeignOperationsBeforeTax_019e640b-7266-7b8f-a254-ee53332920f7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome_019e640b-7266-7c8a-85ca-949da7d56796" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReclassificationAdjustmentsOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncomeBeforeTax_019e640b-7266-74ed-80d7-a461f0fcee60" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReclassificationAdjustmentsOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncomeBeforeTax"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome_019e640b-7266-7c8a-85ca-949da7d56796" xlink:to="loc_ifrs-full_ReclassificationAdjustmentsOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncomeBeforeTax_019e640b-7266-74ed-80d7-a461f0fcee60" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherReclassificationAdjustmentsOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncomeBeforeTax_019e640b-7266-718a-8998-cdee90520217" xlink:href="san-20260630.xsd#san_OtherReclassificationAdjustmentsOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncomeBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome_019e640b-7266-7c8a-85ca-949da7d56796" xlink:to="loc_san_OtherReclassificationAdjustmentsOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncomeBeforeTax_019e640b-7266-718a-8998-cdee90520217" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GainsLossesOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncomeBeforeTax_019e640b-7266-7f83-b7cc-96d2b54d2b83" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_GainsLossesOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncomeBeforeTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome_019e640b-7266-7c8a-85ca-949da7d56796" xlink:to="loc_ifrs-full_GainsLossesOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncomeBeforeTax_019e640b-7266-7f83-b7cc-96d2b54d2b83" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncome_019e640b-7266-7e64-96b3-bed9d53a54aa" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019e640b-7266-7ad4-8a02-7ba01b4e8d08" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncome_019e640b-7266-7e64-96b3-bed9d53a54aa" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax_019e640b-7266-7ad4-8a02-7ba01b4e8d08" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_019e640b-7266-7db9-9fba-ac52b83e8305" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncome_019e640b-7266-7e64-96b3-bed9d53a54aa" xlink:to="loc_ifrs-full_OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax_019e640b-7266-7db9-9fba-ac52b83e8305" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnHedgingInstrumentsThatHedgeInvestmentsInEquityInstruments_019e640b-7266-7a4d-b0b8-ba36694b2d0f" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnHedgingInstrumentsThatHedgeInvestmentsInEquityInstruments"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ChangesInTheFairValueOfEquityInstrumentsMeasuredAtFairValueThroughOtherComprehensiveIncomeHedgingInstrument_019e640b-7266-730d-beab-b4d584819f5e" xlink:href="san-20260630.xsd#san_ChangesInTheFairValueOfEquityInstrumentsMeasuredAtFairValueThroughOtherComprehensiveIncomeHedgingInstrument"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnHedgingInstrumentsThatHedgeInvestmentsInEquityInstruments_019e640b-7266-7a4d-b0b8-ba36694b2d0f" xlink:to="loc_san_ChangesInTheFairValueOfEquityInstrumentsMeasuredAtFairValueThroughOtherComprehensiveIncomeHedgingInstrument_019e640b-7266-730d-beab-b4d584819f5e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ChangesInTheFairValueOfEquityInstrumentsMeasuredAtFairValueThroughOtherComprehensiveIncomeHedgedItem_019e640b-7266-7d36-bd7b-a698324b0253" xlink:href="san-20260630.xsd#san_ChangesInTheFairValueOfEquityInstrumentsMeasuredAtFairValueThroughOtherComprehensiveIncomeHedgedItem"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxGainsLossesOnHedgingInstrumentsThatHedgeInvestmentsInEquityInstruments_019e640b-7266-7a4d-b0b8-ba36694b2d0f" xlink:to="loc_san_ChangesInTheFairValueOfEquityInstrumentsMeasuredAtFairValueThroughOtherComprehensiveIncomeHedgedItem_019e640b-7266-7d36-bd7b-a698324b0253" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherComprehensiveIncomeBeforeTaxHedgingInstrumentsNotDesignated_019e640b-7266-7272-937f-024f765485d9" xlink:href="san-20260630.xsd#san_OtherComprehensiveIncomeBeforeTaxHedgingInstrumentsNotDesignated"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ReclassificationAdjustmentsOnHedgingInstrumentsNotDesignatedBeforeTax_019e640b-7266-7ce9-80a8-b5161ccf1af3" xlink:href="san-20260630.xsd#san_ReclassificationAdjustmentsOnHedgingInstrumentsNotDesignatedBeforeTax"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeBeforeTaxHedgingInstrumentsNotDesignated_019e640b-7266-7272-937f-024f765485d9" xlink:to="loc_san_ReclassificationAdjustmentsOnHedgingInstrumentsNotDesignatedBeforeTax_019e640b-7266-7ce9-80a8-b5161ccf1af3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherReclassificationAdjustmentsOnHedgingInstrumentsNotDesignatedBeforeTax_019e640b-7266-7443-9d4e-91e4044f0477" xlink:href="san-20260630.xsd#san_OtherReclassificationAdjustmentsOnHedgingInstrumentsNotDesignatedBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeBeforeTaxHedgingInstrumentsNotDesignated_019e640b-7266-7272-937f-024f765485d9" xlink:to="loc_san_OtherReclassificationAdjustmentsOnHedgingInstrumentsNotDesignatedBeforeTax_019e640b-7266-7443-9d4e-91e4044f0477" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_GainsLossesOnRemeasuringHedgingInstrumentsNotDesignatedBeforeTax_019e640b-7266-70bc-807e-fd12b3047aea" xlink:href="san-20260630.xsd#san_GainsLossesOnRemeasuringHedgingInstrumentsNotDesignatedBeforeTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeBeforeTaxHedgingInstrumentsNotDesignated_019e640b-7266-7272-937f-024f765485d9" xlink:to="loc_san_GainsLossesOnRemeasuringHedgingInstrumentsNotDesignatedBeforeTax_019e640b-7266-70bc-807e-fd12b3047aea" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxCashFlowHedges_019e640b-7266-711e-b67a-fbb871d98d6b" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncomeBeforeTaxCashFlowHedges"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherReclassificationAdjustmentsOnCashFlowHedgesBeforeTax_019e640b-7266-73f6-81fe-c0ba13b781e1" xlink:href="san-20260630.xsd#san_OtherReclassificationAdjustmentsOnCashFlowHedgesBeforeTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxCashFlowHedges_019e640b-7266-711e-b67a-fbb871d98d6b" xlink:to="loc_san_OtherReclassificationAdjustmentsOnCashFlowHedgesBeforeTax_019e640b-7266-73f6-81fe-c0ba13b781e1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReclassificationAdjustmentsOnCashFlowHedgesBeforeTax_019e640b-7266-7d37-88f1-6bfbd7c55537" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReclassificationAdjustmentsOnCashFlowHedgesBeforeTax"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxCashFlowHedges_019e640b-7266-711e-b67a-fbb871d98d6b" xlink:to="loc_ifrs-full_ReclassificationAdjustmentsOnCashFlowHedgesBeforeTax_019e640b-7266-7d37-88f1-6bfbd7c55537" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_AmountsTransferredToInitialCarryingAmountOfHedgedItemsBeforeTax_019e640b-7266-75d0-8e3a-b085a1b39546" xlink:href="san-20260630.xsd#san_AmountsTransferredToInitialCarryingAmountOfHedgedItemsBeforeTax"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxCashFlowHedges_019e640b-7266-711e-b67a-fbb871d98d6b" xlink:to="loc_san_AmountsTransferredToInitialCarryingAmountOfHedgedItemsBeforeTax_019e640b-7266-75d0-8e3a-b085a1b39546" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GainsLossesOnCashFlowHedgesBeforeTax_019e640b-7266-7c6d-bcff-e35996cdd234" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_GainsLossesOnCashFlowHedgesBeforeTax"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OtherComprehensiveIncomeBeforeTaxCashFlowHedges_019e640b-7266-711e-b67a-fbb871d98d6b" xlink:to="loc_ifrs-full_GainsLossesOnCashFlowHedgesBeforeTax_019e640b-7266-7c6d-bcff-e35996cdd234" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ComprehensiveIncome_019f7000-e5c3-79f1-ab4b-f1d5ece1aead" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ComprehensiveIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLoss_019f7000-e5c3-717a-869b-88fb2265af6a" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ComprehensiveIncome_019f7000-e5c3-79f1-ab4b-f1d5ece1aead" xlink:to="loc_ifrs-full_ProfitLoss_019f7000-e5c3-717a-869b-88fb2265af6a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherComprehensiveIncome_019f7000-e5c3-7089-9140-d89787826c6f" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherComprehensiveIncome"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ComprehensiveIncome_019f7000-e5c3-79f1-ab4b-f1d5ece1aead" xlink:to="loc_ifrs-full_OtherComprehensiveIncome_019f7000-e5c3-7089-9140-d89787826c6f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherComprehensiveIncomeBeforeTaxNonCurrentAssetsClassifiedAsHeldForSale_019e640b-7266-7d05-8b6a-99b3641575a1" xlink:href="san-20260630.xsd#san_OtherComprehensiveIncomeBeforeTaxNonCurrentAssetsClassifiedAsHeldForSale"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_GainsLossesOnNonCurrentAssetsClassifiedAsHeldForSaleBeforeTax_019e640b-7266-76e2-b72d-c530423fa003" xlink:href="san-20260630.xsd#san_GainsLossesOnNonCurrentAssetsClassifiedAsHeldForSaleBeforeTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeBeforeTaxNonCurrentAssetsClassifiedAsHeldForSale_019e640b-7266-7d05-8b6a-99b3641575a1" xlink:to="loc_san_GainsLossesOnNonCurrentAssetsClassifiedAsHeldForSaleBeforeTax_019e640b-7266-76e2-b72d-c530423fa003" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ReclassificationAdjustmentsOnNonCurrentAssetsClassifiedAsHeldForSaleBeforeTax_019e640b-7266-7938-8c56-f73008e63112" xlink:href="san-20260630.xsd#san_ReclassificationAdjustmentsOnNonCurrentAssetsClassifiedAsHeldForSaleBeforeTax"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeBeforeTaxNonCurrentAssetsClassifiedAsHeldForSale_019e640b-7266-7d05-8b6a-99b3641575a1" xlink:to="loc_san_ReclassificationAdjustmentsOnNonCurrentAssetsClassifiedAsHeldForSaleBeforeTax_019e640b-7266-7938-8c56-f73008e63112" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherReclassificationAdjustmentsOnNonCurrentAssetsClassifiedAsHeldForSaleBeforeTax_019e640b-7266-7aeb-b061-a42cc086054f" xlink:href="san-20260630.xsd#san_OtherReclassificationAdjustmentsOnNonCurrentAssetsClassifiedAsHeldForSaleBeforeTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeBeforeTaxNonCurrentAssetsClassifiedAsHeldForSale_019e640b-7266-7d05-8b6a-99b3641575a1" xlink:to="loc_san_OtherReclassificationAdjustmentsOnNonCurrentAssetsClassifiedAsHeldForSaleBeforeTax_019e640b-7266-7aeb-b061-a42cc086054f" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/CondensedConsolidatedStatementsofRecognizedIncomeandExpenseAlternativeCalc" xlink:type="simple" xlink:href="san-20260630.xsd#CondensedConsolidatedStatementsofRecognizedIncomeandExpenseAlternativeCalc"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/CondensedConsolidatedStatementsofRecognizedIncomeandExpenseAlternativeCalc" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ComprehensiveIncome_019f7f8d-2b55-7230-842d-a11c6b093d5b" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ComprehensiveIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ComprehensiveIncomeAttributableToNoncontrollingInterests_019f7f8d-2b55-76e7-8df2-808d845680c0" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ComprehensiveIncomeAttributableToNoncontrollingInterests"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ComprehensiveIncome_019f7f8d-2b55-7230-842d-a11c6b093d5b" xlink:to="loc_ifrs-full_ComprehensiveIncomeAttributableToNoncontrollingInterests_019f7f8d-2b55-76e7-8df2-808d845680c0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ComprehensiveIncomeAttributableToOwnersOfParent_019f7f8d-2b55-718a-ba09-2b4182018c92" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ComprehensiveIncomeAttributableToOwnersOfParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ComprehensiveIncome_019f7f8d-2b55-7230-842d-a11c6b093d5b" xlink:to="loc_ifrs-full_ComprehensiveIncomeAttributableToOwnersOfParent_019f7f8d-2b55-718a-ba09-2b4182018c92" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/CondensedConsolidatedStatementsofChangesinTotalEquity" xlink:type="simple" xlink:href="san-20260630.xsd#CondensedConsolidatedStatementsofChangesinTotalEquity"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/CondensedConsolidatedStatementsofChangesinTotalEquity" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:href="san-20260630.xsd#san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CancellationOfTreasuryShares_019e640b-7266-7fc0-b0f8-984473549d24" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CancellationOfTreasuryShares"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_ifrs-full_CancellationOfTreasuryShares_019e640b-7266-7fc0-b0f8-984473549d24" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncreaseDecreaseThroughSharebasedPaymentTransactions_019e640b-7266-77b2-a075-ccfd8527c518" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IncreaseDecreaseThroughSharebasedPaymentTransactions"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_ifrs-full_IncreaseDecreaseThroughSharebasedPaymentTransactions_019e640b-7266-77b2-a075-ccfd8527c518" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_TransferFromLiabilitiesToEquity_019e640b-7266-721f-84a8-35840cdb410c" xlink:href="san-20260630.xsd#san_TransferFromLiabilitiesToEquity"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_san_TransferFromLiabilitiesToEquity_019e640b-7266-721f-84a8-35840cdb410c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncreaseDecreaseThroughTransfersAndOtherChangesEquity_019e640b-7266-7f4f-a5a6-af7a0b0ac0ee" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IncreaseDecreaseThroughTransfersAndOtherChangesEquity"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_ifrs-full_IncreaseDecreaseThroughTransfersAndOtherChangesEquity_019e640b-7266-7f4f-a5a6-af7a0b0ac0ee" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DividendsPaid_019e640b-7266-7d3a-b7a4-7a645ccb9cf4" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DividendsPaid"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_ifrs-full_DividendsPaid_019e640b-7266-7d3a-b7a4-7a645ccb9cf4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_IssuanceOfPreferredShares_019e640b-7266-7fd5-b5d3-435781c2efce" xlink:href="san-20260630.xsd#san_IssuanceOfPreferredShares"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_san_IssuanceOfPreferredShares_019e640b-7266-7fd5-b5d3-435781c2efce" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncreaseDecreaseThroughAcquisitionOfSubsidiary_019e640b-7266-7b1f-800f-d85272d78abc" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IncreaseDecreaseThroughAcquisitionOfSubsidiary"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_ifrs-full_IncreaseDecreaseThroughAcquisitionOfSubsidiary_019e640b-7266-7b1f-800f-d85272d78abc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_TransferFromEquityToLiabilities_019e640b-7266-7800-97b3-51657e734e82" xlink:href="san-20260630.xsd#san_TransferFromEquityToLiabilities"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_san_TransferFromEquityToLiabilities_019e640b-7266-7800-97b3-51657e734e82" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PurchaseOfTreasuryShares_019e640b-7266-71d8-82b5-f94a2a5a7621" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_PurchaseOfTreasuryShares"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_ifrs-full_PurchaseOfTreasuryShares_019e640b-7266-71d8-82b5-f94a2a5a7621" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IssueOfEquity_019e640b-7266-7d65-8a55-fd38902c67ee" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IssueOfEquity"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_ifrs-full_IssueOfEquity_019e640b-7266-7d65-8a55-fd38902c67ee" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_IncreaseDecreaseThroughTransfersBetweenEquityItems_019e640b-7266-73b7-ac95-3d64a04bcf13" xlink:href="san-20260630.xsd#san_IncreaseDecreaseThroughTransfersBetweenEquityItems"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_san_IncreaseDecreaseThroughTransfersBetweenEquityItems_019e640b-7266-73b7-ac95-3d64a04bcf13" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_MaturityOfOtherFinancialInstruments_019e640b-7266-7bd4-ae29-cfadfe4c526d" xlink:href="san-20260630.xsd#san_MaturityOfOtherFinancialInstruments"/>
    <link:calculationArc order="12" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_san_MaturityOfOtherFinancialInstruments_019e640b-7266-7bd4-ae29-cfadfe4c526d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_IssuanceOfOtherFinancialInstruments_019e640b-7266-71f7-9a2f-c960cb703531" xlink:href="san-20260630.xsd#san_IssuanceOfOtherFinancialInstruments"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_san_IssuanceOfOtherFinancialInstruments_019e640b-7266-71f7-9a2f-c960cb703531" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReductionOfIssuedCapital_019e640b-7266-7c10-b961-9a29fbc2c771" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReductionOfIssuedCapital"/>
    <link:calculationArc order="14" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_ifrs-full_ReductionOfIssuedCapital_019e640b-7266-7c10-b961-9a29fbc2c771" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncreaseDecreaseThroughConversionOfConvertibleInstruments_019e640b-7266-7f01-a05e-a350320e4e33" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IncreaseDecreaseThroughConversionOfConvertibleInstruments"/>
    <link:calculationArc order="15" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInEquityOtherThanComprehensiveIncome_019e640b-7266-7552-be39-ebecc42165d8" xlink:to="loc_ifrs-full_IncreaseDecreaseThroughConversionOfConvertibleInstruments_019e640b-7266-7f01-a05e-a350320e4e33" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="san-20260630.xsd#CondensedConsolidatedStatementsofCashFlows"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_019e640b-7266-7ef6-835a-c499c2f1b86f" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IncreaseDecreaseInCashAndCashEquivalents"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_019e640b-7266-7734-8c29-aa69ddc677f2" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashFlowsFromUsedInOperatingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_019e640b-7266-7ef6-835a-c499c2f1b86f" xlink:to="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_019e640b-7266-7734-8c29-aa69ddc677f2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_019e640b-7266-75a7-ad9a-38d8d155783d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashFlowsFromUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_019e640b-7266-7ef6-835a-c499c2f1b86f" xlink:to="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_019e640b-7266-75a7-ad9a-38d8d155783d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-7266-7384-9e06-828b7a1db986" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashFlowsFromUsedInFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_019e640b-7266-7ef6-835a-c499c2f1b86f" xlink:to="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-7266-7384-9e06-828b7a1db986" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_EffectOfExchangeRateChangesOnCashAndCashEquivalents_019e640b-7266-7d1a-b3d1-6922e1c127c5" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_EffectOfExchangeRateChangesOnCashAndCashEquivalents"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_IncreaseDecreaseInCashAndCashEquivalents_019e640b-7266-7ef6-835a-c499c2f1b86f" xlink:to="loc_ifrs-full_EffectOfExchangeRateChangesOnCashAndCashEquivalents_019e640b-7266-7d1a-b3d1-6922e1c127c5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-7266-7275-8768-d77d595163b2" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashFlowsFromUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OutflowsOfCashFromFinancingActivities_019e640b-7266-7b2b-bbb9-c9339818bef4" xlink:href="san-20260630.xsd#san_OutflowsOfCashFromFinancingActivities"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-7266-7275-8768-d77d595163b2" xlink:to="loc_san_OutflowsOfCashFromFinancingActivities_019e640b-7266-7b2b-bbb9-c9339818bef4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_InflowsOfCashFromFinancingActivities_019e640b-7266-7733-972c-652346db3d9f" xlink:href="san-20260630.xsd#san_InflowsOfCashFromFinancingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-7266-7275-8768-d77d595163b2" xlink:to="loc_san_InflowsOfCashFromFinancingActivities_019e640b-7266-7733-972c-652346db3d9f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashAndCashEquivalents_019e640b-7266-7b8b-950f-501418117352" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashAndCashEquivalents"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashAndBankBalancesAtCentralBanks_019e640b-7266-78d4-8535-afcba1141b8b" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashAndBankBalancesAtCentralBanks"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashAndCashEquivalents_019e640b-7266-7b8b-950f-501418117352" xlink:to="loc_ifrs-full_CashAndBankBalancesAtCentralBanks_019e640b-7266-78d4-8535-afcba1141b8b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherCashAndCashEquivalents_019e640b-7266-7c0a-9881-8250033522e7" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherCashAndCashEquivalents"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashAndCashEquivalents_019e640b-7266-7b8b-950f-501418117352" xlink:to="loc_ifrs-full_OtherCashAndCashEquivalents_019e640b-7266-7c0a-9881-8250033522e7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_BankOverdraftsClassifiedAsCashEquivalents_019e640b-7266-76f7-a354-e8b20eaec2af" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_BankOverdraftsClassifiedAsCashEquivalents"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashAndCashEquivalents_019e640b-7266-7b8b-950f-501418117352" xlink:to="loc_ifrs-full_BankOverdraftsClassifiedAsCashEquivalents_019e640b-7266-76f7-a354-e8b20eaec2af" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashOnHand_019e640b-7266-715f-92ff-d192805c2367" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashOnHand"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashAndCashEquivalents_019e640b-7266-7b8b-950f-501418117352" xlink:to="loc_ifrs-full_CashOnHand_019e640b-7266-715f-92ff-d192805c2367" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsToReconcileProfitLossOtherThanChangesInWorkingCapital_019e640b-7266-74f0-91aa-27caf844afef" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdjustmentsToReconcileProfitLossOtherThanChangesInWorkingCapital"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForDepreciationAndAmortisationExpense_019e640b-7266-73fb-9281-dd90f78521aa" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdjustmentsForDepreciationAndAmortisationExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AdjustmentsToReconcileProfitLossOtherThanChangesInWorkingCapital_019e640b-7266-74f0-91aa-27caf844afef" xlink:to="loc_ifrs-full_AdjustmentsForDepreciationAndAmortisationExpense_019e640b-7266-73fb-9281-dd90f78521aa" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherAdjustmentsForNoncashItems_019e640b-7266-7321-8267-e84869259f4c" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherAdjustmentsForNoncashItems"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AdjustmentsToReconcileProfitLossOtherThanChangesInWorkingCapital_019e640b-7266-74f0-91aa-27caf844afef" xlink:to="loc_ifrs-full_OtherAdjustmentsForNoncashItems_019e640b-7266-7321-8267-e84869259f4c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OutflowsOfCashFromFinancingActivities_019e640b-7266-763f-8f4f-034fe40fe2da" xlink:href="san-20260630.xsd#san_OutflowsOfCashFromFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DividendsPaidClassifiedAsFinancingActivities_019e640b-7266-7567-bdca-28395c59cdec" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DividendsPaidClassifiedAsFinancingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OutflowsOfCashFromFinancingActivities_019e640b-7266-763f-8f4f-034fe40fe2da" xlink:to="loc_ifrs-full_DividendsPaidClassifiedAsFinancingActivities_019e640b-7266-7567-bdca-28395c59cdec" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_RepaymentsOfSubordinatedLiabilities_019e640b-7266-7143-b5f3-79c857813018" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_RepaymentsOfSubordinatedLiabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OutflowsOfCashFromFinancingActivities_019e640b-7266-763f-8f4f-034fe40fe2da" xlink:to="loc_ifrs-full_RepaymentsOfSubordinatedLiabilities_019e640b-7266-7143-b5f3-79c857813018" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_PaymentsToRedeemEntityShares_019e640b-7266-76aa-a258-915435a3a944" xlink:href="san-20260630.xsd#san_PaymentsToRedeemEntityShares"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OutflowsOfCashFromFinancingActivities_019e640b-7266-763f-8f4f-034fe40fe2da" xlink:to="loc_san_PaymentsToRedeemEntityShares_019e640b-7266-76aa-a258-915435a3a944" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_PaymentsToAcquireEntityShares_019e640b-7266-7d17-921b-65cf17ee0881" xlink:href="san-20260630.xsd#san_PaymentsToAcquireEntityShares"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OutflowsOfCashFromFinancingActivities_019e640b-7266-763f-8f4f-034fe40fe2da" xlink:to="loc_san_PaymentsToAcquireEntityShares_019e640b-7266-7d17-921b-65cf17ee0881" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherOutflowsOfCashClassifiedAsFinancingActivities_019e640b-7266-7d40-a2a5-b1cf7257bf63" xlink:href="san-20260630.xsd#san_OtherOutflowsOfCashClassifiedAsFinancingActivities"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OutflowsOfCashFromFinancingActivities_019e640b-7266-763f-8f4f-034fe40fe2da" xlink:to="loc_san_OtherOutflowsOfCashClassifiedAsFinancingActivities_019e640b-7266-7d40-a2a5-b1cf7257bf63" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InflowsOfCashFromInvestingActivities_019e640b-7266-7907-b94a-d4b3e30ca96d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InflowsOfCashFromInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromLosingControlOfSubsidiariesOrOtherBusinessesClassifiedAsInvestingActivities_019e640b-7266-73a6-9af4-ac94c64e8302" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashFlowsFromLosingControlOfSubsidiariesOrOtherBusinessesClassifiedAsInvestingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_InflowsOfCashFromInvestingActivities_019e640b-7266-7907-b94a-d4b3e30ca96d" xlink:to="loc_ifrs-full_CashFlowsFromLosingControlOfSubsidiariesOrOtherBusinessesClassifiedAsInvestingActivities_019e640b-7266-73a6-9af4-ac94c64e8302" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromDisposalOfNoncurrentAssetsOrDisposalGroupsClassifiedAsHeldForSaleAndDiscontinuedOperations_019e640b-7266-744f-8794-90bf1588473f" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProceedsFromDisposalOfNoncurrentAssetsOrDisposalGroupsClassifiedAsHeldForSaleAndDiscontinuedOperations"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_InflowsOfCashFromInvestingActivities_019e640b-7266-7907-b94a-d4b3e30ca96d" xlink:to="loc_ifrs-full_ProceedsFromDisposalOfNoncurrentAssetsOrDisposalGroupsClassifiedAsHeldForSaleAndDiscontinuedOperations_019e640b-7266-744f-8794-90bf1588473f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromSalesOfIntangibleAssetsClassifiedAsInvestingActivities_019e640b-7266-7478-8e54-55fd38076239" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProceedsFromSalesOfIntangibleAssetsClassifiedAsInvestingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_InflowsOfCashFromInvestingActivities_019e640b-7266-7907-b94a-d4b3e30ca96d" xlink:to="loc_ifrs-full_ProceedsFromSalesOfIntangibleAssetsClassifiedAsInvestingActivities_019e640b-7266-7478-8e54-55fd38076239" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromSalesOfInvestmentsAccountedForUsingEquityMethod_019e640b-7266-7093-a63a-ef5c6901b611" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProceedsFromSalesOfInvestmentsAccountedForUsingEquityMethod"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_InflowsOfCashFromInvestingActivities_019e640b-7266-7907-b94a-d4b3e30ca96d" xlink:to="loc_ifrs-full_ProceedsFromSalesOfInvestmentsAccountedForUsingEquityMethod_019e640b-7266-7093-a63a-ef5c6901b611" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherProceedsOfCashClassifiedAsInvestingActivities_019e640b-7266-745e-b7d0-e1290ce29ac2" xlink:href="san-20260630.xsd#san_OtherProceedsOfCashClassifiedAsInvestingActivities"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_InflowsOfCashFromInvestingActivities_019e640b-7266-7907-b94a-d4b3e30ca96d" xlink:to="loc_san_OtherProceedsOfCashClassifiedAsInvestingActivities_019e640b-7266-745e-b7d0-e1290ce29ac2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromSalesOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities_019e640b-7266-7bb3-954d-2129cceb6c33" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProceedsFromSalesOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_InflowsOfCashFromInvestingActivities_019e640b-7266-7907-b94a-d4b3e30ca96d" xlink:to="loc_ifrs-full_ProceedsFromSalesOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities_019e640b-7266-7bb3-954d-2129cceb6c33" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_AdjustmentsForDecreaseIncreaseInOperatingAssets_019e640b-7266-7ecb-ae98-dfe05a3eeaa2" xlink:href="san-20260630.xsd#san_AdjustmentsForDecreaseIncreaseInOperatingAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInFinancialAssetsHeldForTrading_019e640b-7266-7d30-8eb6-c457fb7b1f15" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdjustmentsForDecreaseIncreaseInFinancialAssetsHeldForTrading"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_AdjustmentsForDecreaseIncreaseInOperatingAssets_019e640b-7266-7ecb-ae98-dfe05a3eeaa2" xlink:to="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInFinancialAssetsHeldForTrading_019e640b-7266-7d30-8eb6-c457fb7b1f15" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_AdjustmentsForDecreaseIncreaseInNonTradingFinancialAssetsMandatorilyAtFairValueThroughProfitOrLoss_019e640b-7266-72db-a3ea-75ce7d081bc8" xlink:href="san-20260630.xsd#san_AdjustmentsForDecreaseIncreaseInNonTradingFinancialAssetsMandatorilyAtFairValueThroughProfitOrLoss"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_AdjustmentsForDecreaseIncreaseInOperatingAssets_019e640b-7266-7ecb-ae98-dfe05a3eeaa2" xlink:to="loc_san_AdjustmentsForDecreaseIncreaseInNonTradingFinancialAssetsMandatorilyAtFairValueThroughProfitOrLoss_019e640b-7266-72db-a3ea-75ce7d081bc8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInFinancialAssetsMeasuredAtFairValueThroughProfitOrLoss_019e640b-7266-7c56-9ccb-abb5a48666c4" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdjustmentsForDecreaseIncreaseInFinancialAssetsMeasuredAtFairValueThroughProfitOrLoss"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_AdjustmentsForDecreaseIncreaseInOperatingAssets_019e640b-7266-7ecb-ae98-dfe05a3eeaa2" xlink:to="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInFinancialAssetsMeasuredAtFairValueThroughProfitOrLoss_019e640b-7266-7c56-9ccb-abb5a48666c4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome_019e640b-7266-7269-82aa-5f91a3018aa5" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdjustmentsForDecreaseIncreaseInFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_AdjustmentsForDecreaseIncreaseInOperatingAssets_019e640b-7266-7ecb-ae98-dfe05a3eeaa2" xlink:to="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome_019e640b-7266-7269-82aa-5f91a3018aa5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInFinancialAssetsMeasuredAtAmortisedCost_019e640b-7266-74c0-9a6d-10f6b922a2d8" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdjustmentsForDecreaseIncreaseInFinancialAssetsMeasuredAtAmortisedCost"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_AdjustmentsForDecreaseIncreaseInOperatingAssets_019e640b-7266-7ecb-ae98-dfe05a3eeaa2" xlink:to="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInFinancialAssetsMeasuredAtAmortisedCost_019e640b-7266-74c0-9a6d-10f6b922a2d8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInOtherAssets_019e640b-7266-7e1a-8ccd-9fd5f46f1acf" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdjustmentsForDecreaseIncreaseInOtherAssets"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_AdjustmentsForDecreaseIncreaseInOperatingAssets_019e640b-7266-7ecb-ae98-dfe05a3eeaa2" xlink:to="loc_ifrs-full_AdjustmentsForDecreaseIncreaseInOtherAssets_019e640b-7266-7e1a-8ccd-9fd5f46f1acf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition_019e640b-7266-7cf1-a4d3-7a91e1df77a3" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashAndCashEquivalents_019e640b-7266-7ec4-a178-d1131d98e5d0" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashAndCashEquivalents"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition_019e640b-7266-7cf1-a4d3-7a91e1df77a3" xlink:to="loc_ifrs-full_CashAndCashEquivalents_019e640b-7266-7ec4-a178-d1131d98e5d0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashAndCashEquivalentsClassifiedAsPartOfDisposalGroupHeldForSale_019e640b-7266-7ac0-9337-4b23d20fd5ec" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashAndCashEquivalentsClassifiedAsPartOfDisposalGroupHeldForSale"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition_019e640b-7266-7cf1-a4d3-7a91e1df77a3" xlink:to="loc_ifrs-full_CashAndCashEquivalentsClassifiedAsPartOfDisposalGroupHeldForSale_019e640b-7266-7ac0-9337-4b23d20fd5ec" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OutflowsOfCashFromInvestingActivities_019e640b-7266-7979-9691-6d5be4cc183a" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OutflowsOfCashFromInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsUsedInObtainingControlOfSubsidiariesOrOtherBusinessesClassifiedAsInvestingActivities_019e640b-7266-7007-ae58-99d3fd5dab3b" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashFlowsUsedInObtainingControlOfSubsidiariesOrOtherBusinessesClassifiedAsInvestingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OutflowsOfCashFromInvestingActivities_019e640b-7266-7979-9691-6d5be4cc183a" xlink:to="loc_ifrs-full_CashFlowsUsedInObtainingControlOfSubsidiariesOrOtherBusinessesClassifiedAsInvestingActivities_019e640b-7266-7007-ae58-99d3fd5dab3b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherPaymentsOfCashClassifiedAsInvestingActivities_019e640b-7266-748d-934d-997ed671c25b" xlink:href="san-20260630.xsd#san_OtherPaymentsOfCashClassifiedAsInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OutflowsOfCashFromInvestingActivities_019e640b-7266-7979-9691-6d5be4cc183a" xlink:to="loc_san_OtherPaymentsOfCashClassifiedAsInvestingActivities_019e640b-7266-748d-934d-997ed671c25b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PurchaseOfInterestsInInvestmentsAccountedForUsingEquityMethod_019e640b-7266-7d09-90e3-40c40327ceb1" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_PurchaseOfInterestsInInvestmentsAccountedForUsingEquityMethod"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OutflowsOfCashFromInvestingActivities_019e640b-7266-7979-9691-6d5be4cc183a" xlink:to="loc_ifrs-full_PurchaseOfInterestsInInvestmentsAccountedForUsingEquityMethod_019e640b-7266-7d09-90e3-40c40327ceb1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities_019e640b-7266-7130-ac09-9d57299ab08d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OutflowsOfCashFromInvestingActivities_019e640b-7266-7979-9691-6d5be4cc183a" xlink:to="loc_ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities_019e640b-7266-7130-ac09-9d57299ab08d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities_019e640b-7266-739b-844a-52c7c3b038f8" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OutflowsOfCashFromInvestingActivities_019e640b-7266-7979-9691-6d5be4cc183a" xlink:to="loc_ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities_019e640b-7266-739b-844a-52c7c3b038f8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_PurchaseOfNonCurrentAssetsAndLiabilitiesClassifiedAsHeldForSale_019e640b-7266-79c9-b4b4-5baf8fac4c94" xlink:href="san-20260630.xsd#san_PurchaseOfNonCurrentAssetsAndLiabilitiesClassifiedAsHeldForSale"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_OutflowsOfCashFromInvestingActivities_019e640b-7266-7979-9691-6d5be4cc183a" xlink:to="loc_san_PurchaseOfNonCurrentAssetsAndLiabilitiesClassifiedAsHeldForSale_019e640b-7266-79c9-b4b4-5baf8fac4c94" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_InflowsOfCashFromFinancingActivities_019e640b-7266-7d83-bcaf-9f11a0af33fa" xlink:href="san-20260630.xsd#san_InflowsOfCashFromFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromIssueOfSubordinatedLiabilities_019e640b-7266-7aed-ac9f-d0e0a54d6904" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProceedsFromIssueOfSubordinatedLiabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_InflowsOfCashFromFinancingActivities_019e640b-7266-7d83-bcaf-9f11a0af33fa" xlink:to="loc_ifrs-full_ProceedsFromIssueOfSubordinatedLiabilities_019e640b-7266-7aed-ac9f-d0e0a54d6904" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromIssuingShares_019e640b-7266-74c0-9b8b-02e7f64dc00b" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProceedsFromIssuingShares"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_InflowsOfCashFromFinancingActivities_019e640b-7266-7d83-bcaf-9f11a0af33fa" xlink:to="loc_ifrs-full_ProceedsFromIssuingShares_019e640b-7266-74c0-9b8b-02e7f64dc00b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherInflowsOfCashClassifiedAsFinancingActivities_019e640b-7266-76eb-bed1-19f2c3e33b82" xlink:href="san-20260630.xsd#san_OtherInflowsOfCashClassifiedAsFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_InflowsOfCashFromFinancingActivities_019e640b-7266-7d83-bcaf-9f11a0af33fa" xlink:to="loc_san_OtherInflowsOfCashClassifiedAsFinancingActivities_019e640b-7266-76eb-bed1-19f2c3e33b82" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromSaleOrIssueOfTreasuryShares_019e640b-7266-7347-81b0-7da9a88c46df" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProceedsFromSaleOrIssueOfTreasuryShares"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_InflowsOfCashFromFinancingActivities_019e640b-7266-7d83-bcaf-9f11a0af33fa" xlink:to="loc_ifrs-full_ProceedsFromSaleOrIssueOfTreasuryShares_019e640b-7266-7347-81b0-7da9a88c46df" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_019e640b-7266-7611-a533-4971a9a3235d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashFlowsFromUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OutflowsOfCashFromInvestingActivities_019e640b-7266-7236-ac7e-bb46e5943269" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OutflowsOfCashFromInvestingActivities"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_019e640b-7266-7611-a533-4971a9a3235d" xlink:to="loc_ifrs-full_OutflowsOfCashFromInvestingActivities_019e640b-7266-7236-ac7e-bb46e5943269" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InflowsOfCashFromInvestingActivities_019e640b-7266-7409-850f-95a4bfe8df69" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InflowsOfCashFromInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInInvestingActivities_019e640b-7266-7611-a533-4971a9a3235d" xlink:to="loc_ifrs-full_InflowsOfCashFromInvestingActivities_019e640b-7266-7409-850f-95a4bfe8df69" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_AdjustmentsForIncreaseDecreaseInOperatingLiabilities_019e640b-7266-7632-bfaa-e3e920167408" xlink:href="san-20260630.xsd#san_AdjustmentsForIncreaseDecreaseInOperatingLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInFinancialLiabilitiesHeldForTrading_019e640b-7266-7eed-ae5b-dd9ff158d870" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdjustmentsForIncreaseDecreaseInFinancialLiabilitiesHeldForTrading"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_AdjustmentsForIncreaseDecreaseInOperatingLiabilities_019e640b-7266-7632-bfaa-e3e920167408" xlink:to="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInFinancialLiabilitiesHeldForTrading_019e640b-7266-7eed-ae5b-dd9ff158d870" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInFinancialLiabilitiesMeasuredAtFairValueThroughProfitOrLoss_019e640b-7266-797e-b67a-869c500e4f6d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdjustmentsForIncreaseDecreaseInFinancialLiabilitiesMeasuredAtFairValueThroughProfitOrLoss"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_AdjustmentsForIncreaseDecreaseInOperatingLiabilities_019e640b-7266-7632-bfaa-e3e920167408" xlink:to="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInFinancialLiabilitiesMeasuredAtFairValueThroughProfitOrLoss_019e640b-7266-797e-b67a-869c500e4f6d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInFinancialLiabilitiesMeasuredAtAmortisedCost_019e640b-7266-7566-9821-3c0f265e5480" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdjustmentsForIncreaseDecreaseInFinancialLiabilitiesMeasuredAtAmortisedCost"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_AdjustmentsForIncreaseDecreaseInOperatingLiabilities_019e640b-7266-7632-bfaa-e3e920167408" xlink:to="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInFinancialLiabilitiesMeasuredAtAmortisedCost_019e640b-7266-7566-9821-3c0f265e5480" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInOtherLiabilities_019e640b-7266-78f1-8453-86831fe7aa27" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdjustmentsForIncreaseDecreaseInOtherLiabilities"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_AdjustmentsForIncreaseDecreaseInOperatingLiabilities_019e640b-7266-7632-bfaa-e3e920167408" xlink:to="loc_ifrs-full_AdjustmentsForIncreaseDecreaseInOtherLiabilities_019e640b-7266-78f1-8453-86831fe7aa27" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_019e640b-7266-7b99-bb03-19e810c25e96" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashFlowsFromUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLoss_019e640b-7266-71a1-a3e3-1f03c9808307" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_019e640b-7266-7b99-bb03-19e810c25e96" xlink:to="loc_ifrs-full_ProfitLoss_019e640b-7266-71a1-a3e3-1f03c9808307" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustmentsToReconcileProfitLossOtherThanChangesInWorkingCapital_019e640b-7266-72c0-b143-2d69467ff189" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdjustmentsToReconcileProfitLossOtherThanChangesInWorkingCapital"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_019e640b-7266-7b99-bb03-19e810c25e96" xlink:to="loc_ifrs-full_AdjustmentsToReconcileProfitLossOtherThanChangesInWorkingCapital_019e640b-7266-72c0-b143-2d69467ff189" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_AdjustmentsForDecreaseIncreaseInOperatingAssets_019e640b-7266-79ea-a062-bca83afe656a" xlink:href="san-20260630.xsd#san_AdjustmentsForDecreaseIncreaseInOperatingAssets"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_019e640b-7266-7b99-bb03-19e810c25e96" xlink:to="loc_san_AdjustmentsForDecreaseIncreaseInOperatingAssets_019e640b-7266-79ea-a062-bca83afe656a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_AdjustmentsForIncreaseDecreaseInOperatingLiabilities_019e640b-7266-7a67-868f-494c8b14a75d" xlink:href="san-20260630.xsd#san_AdjustmentsForIncreaseDecreaseInOperatingLiabilities"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_019e640b-7266-7b99-bb03-19e810c25e96" xlink:to="loc_san_AdjustmentsForIncreaseDecreaseInOperatingLiabilities_019e640b-7266-7a67-868f-494c8b14a75d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities_019e640b-7266-7e02-85fe-3b8835c64826" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInOperatingActivities_019e640b-7266-7b99-bb03-19e810c25e96" xlink:to="loc_ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities_019e640b-7266-7e02-85fe-3b8835c64826" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/GrupoSantanderTSDBankingGroupplcAssetsAcquiredandLiabilitiesAssumedDetails" xlink:type="simple" xlink:href="san-20260630.xsd#GrupoSantanderTSDBankingGroupplcAssetsAcquiredandLiabilitiesAssumedDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/GrupoSantanderTSDBankingGroupplcAssetsAcquiredandLiabilitiesAssumedDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_san_IdentifiableAssetsAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7e07-a0c7-2f537829ab78" xlink:href="san-20260630.xsd#san_IdentifiableAssetsAcquiredRecognisedAsOfAcquisitionDate"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashAndCashEquivalentsRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7c60-b4e4-b40508458902" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashAndCashEquivalentsRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableAssetsAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7e07-a0c7-2f537829ab78" xlink:to="loc_ifrs-full_CashAndCashEquivalentsRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7c60-b4e4-b40508458902" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_FinancialInstrumentsAssetsRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7f0c-ad19-e3aebf8c465c" xlink:href="san-20260630.xsd#san_FinancialInstrumentsAssetsRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableAssetsAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7e07-a0c7-2f537829ab78" xlink:to="loc_san_FinancialInstrumentsAssetsRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7f0c-ad19-e3aebf8c465c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DepositsWithCreditInstitutionsAssetsRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-76fe-a94f-780e33467779" xlink:href="san-20260630.xsd#san_DepositsWithCreditInstitutionsAssetsRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableAssetsAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7e07-a0c7-2f537829ab78" xlink:to="loc_san_DepositsWithCreditInstitutionsAssetsRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-76fe-a94f-780e33467779" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_LoansToCustomersAssetsRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-779b-a5a4-90527b85c586" xlink:href="san-20260630.xsd#san_LoansToCustomersAssetsRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableAssetsAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7e07-a0c7-2f537829ab78" xlink:to="loc_san_LoansToCustomersAssetsRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-779b-a5a4-90527b85c586" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_FinancialAssetsAtFairValueThroughOtherComprehensiveIncomeRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-72d8-bd65-412f2e14b09f" xlink:href="san-20260630.xsd#san_FinancialAssetsAtFairValueThroughOtherComprehensiveIncomeRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableAssetsAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7e07-a0c7-2f537829ab78" xlink:to="loc_san_FinancialAssetsAtFairValueThroughOtherComprehensiveIncomeRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-72d8-bd65-412f2e14b09f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IdentifiableIntangibleAssetsRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7515-a712-1bc173e9e341" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IdentifiableIntangibleAssetsRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableAssetsAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7e07-a0c7-2f537829ab78" xlink:to="loc_ifrs-full_IdentifiableIntangibleAssetsRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7515-a712-1bc173e9e341" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PropertyPlantAndEquipmentRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-76d0-800b-017203c2cefd" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_PropertyPlantAndEquipmentRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableAssetsAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7e07-a0c7-2f537829ab78" xlink:to="loc_ifrs-full_PropertyPlantAndEquipmentRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-76d0-800b-017203c2cefd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherAssetsRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-74df-a29f-5261ae5003d9" xlink:href="san-20260630.xsd#san_OtherAssetsRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableAssetsAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-7e07-a0c7-2f537829ab78" xlink:to="loc_san_OtherAssetsRecognisedAsOfAcquisitionDate_019f5fa5-e3bf-74df-a29f-5261ae5003d9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IdentifiableAssetsAcquiredLiabilitiesAssumed_019f5fa6-1156-73cc-a3d8-451fdaa3d0c6" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IdentifiableAssetsAcquiredLiabilitiesAssumed"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_IdentifiableAssetsAcquiredRecognisedAsOfAcquisitionDate_019f5fa6-1156-7ae1-b6f4-4b9671c7b60b" xlink:href="san-20260630.xsd#san_IdentifiableAssetsAcquiredRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_IdentifiableAssetsAcquiredLiabilitiesAssumed_019f5fa6-1156-73cc-a3d8-451fdaa3d0c6" xlink:to="loc_san_IdentifiableAssetsAcquiredRecognisedAsOfAcquisitionDate_019f5fa6-1156-7ae1-b6f4-4b9671c7b60b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_IdentifiableLiabilitiesAcquiredRecognisedAsOfAcquisitionDate_019f5fa6-1156-713e-8ad4-d6c4a1f08245" xlink:href="san-20260630.xsd#san_IdentifiableLiabilitiesAcquiredRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_IdentifiableAssetsAcquiredLiabilitiesAssumed_019f5fa6-1156-73cc-a3d8-451fdaa3d0c6" xlink:to="loc_san_IdentifiableLiabilitiesAcquiredRecognisedAsOfAcquisitionDate_019f5fa6-1156-713e-8ad4-d6c4a1f08245" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_IdentifiableLiabilitiesAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-f64b-7420-a832-1a24fa95bb4c" xlink:href="san-20260630.xsd#san_IdentifiableLiabilitiesAcquiredRecognisedAsOfAcquisitionDate"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_CashAndBalancesWithCentralBanksLiabilitiesRecognisedAsOfAcquisitionDate_019f5fa5-f64b-7f91-8601-0409a335faba" xlink:href="san-20260630.xsd#san_CashAndBalancesWithCentralBanksLiabilitiesRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableLiabilitiesAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-f64b-7420-a832-1a24fa95bb4c" xlink:to="loc_san_CashAndBalancesWithCentralBanksLiabilitiesRecognisedAsOfAcquisitionDate_019f5fa5-f64b-7f91-8601-0409a335faba" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_FinancialInstrumentsLiabilitiesRecognisedAsOfAcquisitionDate_019f5fa5-f64b-7890-acfa-627b5ba334a5" xlink:href="san-20260630.xsd#san_FinancialInstrumentsLiabilitiesRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableLiabilitiesAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-f64b-7420-a832-1a24fa95bb4c" xlink:to="loc_san_FinancialInstrumentsLiabilitiesRecognisedAsOfAcquisitionDate_019f5fa5-f64b-7890-acfa-627b5ba334a5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_LoansFromCustomersLiabilitiesRecognisedAsOfAcquisitionDate_019f5fa5-f64b-76a4-88cd-7c79d645d0fd" xlink:href="san-20260630.xsd#san_LoansFromCustomersLiabilitiesRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableLiabilitiesAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-f64b-7420-a832-1a24fa95bb4c" xlink:to="loc_san_LoansFromCustomersLiabilitiesRecognisedAsOfAcquisitionDate_019f5fa5-f64b-76a4-88cd-7c79d645d0fd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DebtSecuritiesInIssueAndOtherFinancialLiabilitiesRecognisedAsOfAcquisitionDate_019f5fa5-f64b-792b-9144-d0339dddb894" xlink:href="san-20260630.xsd#san_DebtSecuritiesInIssueAndOtherFinancialLiabilitiesRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableLiabilitiesAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-f64b-7420-a832-1a24fa95bb4c" xlink:to="loc_san_DebtSecuritiesInIssueAndOtherFinancialLiabilitiesRecognisedAsOfAcquisitionDate_019f5fa5-f64b-792b-9144-d0339dddb894" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_SubordinatedDebtRecognisedAsOfAcquisitionDate_019f5fa5-f64b-781c-9582-fa59096ae1c3" xlink:href="san-20260630.xsd#san_SubordinatedDebtRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableLiabilitiesAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-f64b-7420-a832-1a24fa95bb4c" xlink:to="loc_san_SubordinatedDebtRecognisedAsOfAcquisitionDate_019f5fa5-f64b-781c-9582-fa59096ae1c3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherLiabilitiesRecognisedAsOfAcquisitionDate_019f5fa5-f64b-7578-ad8a-c7e76153841d" xlink:href="san-20260630.xsd#san_OtherLiabilitiesRecognisedAsOfAcquisitionDate"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IdentifiableLiabilitiesAcquiredRecognisedAsOfAcquisitionDate_019f5fa5-f64b-7420-a832-1a24fa95bb4c" xlink:to="loc_san_OtherLiabilitiesRecognisedAsOfAcquisitionDate_019f5fa5-f64b-7578-ad8a-c7e76153841d" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/ShareholderremunerationsystemandearningspershareScheduleofshareholderremunerationDetails" xlink:type="simple" xlink:href="san-20260630.xsd#ShareholderremunerationsystemandearningspershareScheduleofshareholderremunerationDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/ShareholderremunerationsystemandearningspershareScheduleofshareholderremunerationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidOrdinaryAndOtherShares_019ef48f-29f8-7c58-a123-fae855544502" xlink:href="san-20260630.xsd#san_DividendsPaidOrdinaryAndOtherShares"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DividendsPaidOtherShares_019ef48f-29f8-71ad-8846-e4e932f98a1e" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DividendsPaidOtherShares"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherShares_019ef48f-29f8-7c58-a123-fae855544502" xlink:to="loc_ifrs-full_DividendsPaidOtherShares_019ef48f-29f8-71ad-8846-e4e932f98a1e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DividendsPaidOrdinaryShares_019ef48f-29f8-71a9-a214-15076f1af19d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DividendsPaidOrdinaryShares"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherShares_019ef48f-29f8-7c58-a123-fae855544502" xlink:to="loc_ifrs-full_DividendsPaidOrdinaryShares_019ef48f-29f8-71a9-a214-15076f1af19d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidOrdinaryAndOtherSharesPercentageOfParValue_019ef48f-29f8-72bb-b8c2-764e00bf7b10" xlink:href="san-20260630.xsd#san_DividendsPaidOrdinaryAndOtherSharesPercentageOfParValue"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidWithChargeToReservesOrSharePremiumPercentageOfParValue_019ef48f-29f8-787c-8ff0-102249e07799" xlink:href="san-20260630.xsd#san_DividendsPaidWithChargeToReservesOrSharePremiumPercentageOfParValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherSharesPercentageOfParValue_019ef48f-29f8-72bb-b8c2-764e00bf7b10" xlink:to="loc_san_DividendsPaidWithChargeToReservesOrSharePremiumPercentageOfParValue_019ef48f-29f8-787c-8ff0-102249e07799" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_FlexiblePaymentPercentageOfParValue_019ef48f-29f8-7bce-a46d-4a41c72dc786" xlink:href="san-20260630.xsd#san_FlexiblePaymentPercentageOfParValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherSharesPercentageOfParValue_019ef48f-29f8-72bb-b8c2-764e00bf7b10" xlink:to="loc_san_FlexiblePaymentPercentageOfParValue_019ef48f-29f8-7bce-a46d-4a41c72dc786" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidOutOfProfitPercentageOfParValue_019ef48f-29f8-780f-bb50-6881f759b521" xlink:href="san-20260630.xsd#san_DividendsPaidOutOfProfitPercentageOfParValue"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherSharesPercentageOfParValue_019ef48f-29f8-72bb-b8c2-764e00bf7b10" xlink:to="loc_san_DividendsPaidOutOfProfitPercentageOfParValue_019ef48f-29f8-780f-bb50-6881f759b521" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendInKindPercentageOfParValue_019ef48f-29f8-7b44-82ad-a9559622c12c" xlink:href="san-20260630.xsd#san_DividendInKindPercentageOfParValue"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherSharesPercentageOfParValue_019ef48f-29f8-72bb-b8c2-764e00bf7b10" xlink:to="loc_san_DividendInKindPercentageOfParValue_019ef48f-29f8-7b44-82ad-a9559622c12c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidOrdinaryAndOtherSharesPerShare_019ef48f-29f8-7237-bfca-8a92c3909959" xlink:href="san-20260630.xsd#san_DividendsPaidOrdinaryAndOtherSharesPerShare"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidWithChargeToReservesOrSharePremiumPerShare_019ef48f-29f8-779d-bb74-5472a9f6486a" xlink:href="san-20260630.xsd#san_DividendsPaidWithChargeToReservesOrSharePremiumPerShare"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherSharesPerShare_019ef48f-29f8-7237-bfca-8a92c3909959" xlink:to="loc_san_DividendsPaidWithChargeToReservesOrSharePremiumPerShare_019ef48f-29f8-779d-bb74-5472a9f6486a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendInKindPerShare_019ef48f-29f8-75b6-9aab-35f1514694c2" xlink:href="san-20260630.xsd#san_DividendInKindPerShare"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherSharesPerShare_019ef48f-29f8-7237-bfca-8a92c3909959" xlink:to="loc_san_DividendInKindPerShare_019ef48f-29f8-75b6-9aab-35f1514694c2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidOutOfProfitPerShare_019ef48f-29f8-768a-9c6b-25bf0bf190e8" xlink:href="san-20260630.xsd#san_DividendsPaidOutOfProfitPerShare"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherSharesPerShare_019ef48f-29f8-7237-bfca-8a92c3909959" xlink:to="loc_san_DividendsPaidOutOfProfitPerShare_019ef48f-29f8-768a-9c6b-25bf0bf190e8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_FlexiblePaymentPerShare_019ef48f-29f8-72b1-96c5-33afb1b2e2be" xlink:href="san-20260630.xsd#san_FlexiblePaymentPerShare"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherSharesPerShare_019ef48f-29f8-7237-bfca-8a92c3909959" xlink:to="loc_san_FlexiblePaymentPerShare_019ef48f-29f8-72b1-96c5-33afb1b2e2be" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/ShareholderremunerationsystemandearningspershareScheduleofshareholderremunerationDetails_1" xlink:type="simple" xlink:href="san-20260630.xsd#ShareholderremunerationsystemandearningspershareScheduleofshareholderremunerationDetails_1"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/ShareholderremunerationsystemandearningspershareScheduleofshareholderremunerationDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidOrdinaryAndOtherShares_019ef48f-29f8-77f1-ac5e-ca43882ff281" xlink:href="san-20260630.xsd#san_DividendsPaidOrdinaryAndOtherShares"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendInKind_019ef48f-29f8-77cb-b7c6-1061ef92dcc7" xlink:href="san-20260630.xsd#san_DividendInKind"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherShares_019ef48f-29f8-77f1-ac5e-ca43882ff281" xlink:to="loc_san_DividendInKind_019ef48f-29f8-77cb-b7c6-1061ef92dcc7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_FlexiblePayment_019ef48f-29f8-7e10-8057-2a780dc770d5" xlink:href="san-20260630.xsd#san_FlexiblePayment"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherShares_019ef48f-29f8-77f1-ac5e-ca43882ff281" xlink:to="loc_san_FlexiblePayment_019ef48f-29f8-7e10-8057-2a780dc770d5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidOutOfProfit_019ef48f-29f8-7c4a-9bf4-00ca03d00fdc" xlink:href="san-20260630.xsd#san_DividendsPaidOutOfProfit"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherShares_019ef48f-29f8-77f1-ac5e-ca43882ff281" xlink:to="loc_san_DividendsPaidOutOfProfit_019ef48f-29f8-7c4a-9bf4-00ca03d00fdc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidWithChargeToReservesOrSharePremium_019ef48f-29f8-7c06-8a07-e4f87ff71c2e" xlink:href="san-20260630.xsd#san_DividendsPaidWithChargeToReservesOrSharePremium"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherShares_019ef48f-29f8-77f1-ac5e-ca43882ff281" xlink:to="loc_san_DividendsPaidWithChargeToReservesOrSharePremium_019ef48f-29f8-7c06-8a07-e4f87ff71c2e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidOrdinaryAndOtherSharesPercentageOfParValue_019ef48f-29f8-7924-a51d-3b4e4b40f71f" xlink:href="san-20260630.xsd#san_DividendsPaidOrdinaryAndOtherSharesPercentageOfParValue"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidPercentageOfParValueOtherShares_019ef48f-29f8-781d-a3cb-19350fc48b72" xlink:href="san-20260630.xsd#san_DividendsPaidPercentageOfParValueOtherShares"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherSharesPercentageOfParValue_019ef48f-29f8-7924-a51d-3b4e4b40f71f" xlink:to="loc_san_DividendsPaidPercentageOfParValueOtherShares_019ef48f-29f8-781d-a3cb-19350fc48b72" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidOrdinarySharesPercentageOfParValue_019ef48f-29f8-707d-9a8b-1ca56aeb295b" xlink:href="san-20260630.xsd#san_DividendsPaidOrdinarySharesPercentageOfParValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherSharesPercentageOfParValue_019ef48f-29f8-7924-a51d-3b4e4b40f71f" xlink:to="loc_san_DividendsPaidOrdinarySharesPercentageOfParValue_019ef48f-29f8-707d-9a8b-1ca56aeb295b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsPaidOrdinaryAndOtherSharesPerShare_019ef48f-29f8-770a-8668-45663d4e033c" xlink:href="san-20260630.xsd#san_DividendsPaidOrdinaryAndOtherSharesPerShare"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DividendsPaidOtherSharesPerShare_019ef48f-29f8-74a4-99c7-c31e611a338b" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DividendsPaidOtherSharesPerShare"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherSharesPerShare_019ef48f-29f8-770a-8668-45663d4e033c" xlink:to="loc_ifrs-full_DividendsPaidOtherSharesPerShare_019ef48f-29f8-74a4-99c7-c31e611a338b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DividendsPaidOrdinarySharesPerShare_019ef48f-29f8-76b1-b760-79056d6e5cf7" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DividendsPaidOrdinarySharesPerShare"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_DividendsPaidOrdinaryAndOtherSharesPerShare_019ef48f-29f8-770a-8668-45663d4e033c" xlink:to="loc_ifrs-full_DividendsPaidOrdinarySharesPerShare_019ef48f-29f8-76b1-b760-79056d6e5cf7" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/ShareholderremunerationsystemandearningspershareScheduleofbasicearningspershareDetails" xlink:type="simple" xlink:href="san-20260630.xsd#ShareholderremunerationsystemandearningspershareScheduleofbasicearningspershareDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/ShareholderremunerationsystemandearningspershareScheduleofbasicearningspershareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_BasicEarningsLossPerShare_019e640b-7266-7528-a5e6-4a59bf9e837e" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_BasicEarningsLossPerShare"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_BasicEarningsLossPerShareFromDiscontinuedOperations_019e640b-7314-79f6-933e-f1d1a17e6df3" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_BasicEarningsLossPerShareFromDiscontinuedOperations"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_BasicEarningsLossPerShare_019e640b-7266-7528-a5e6-4a59bf9e837e" xlink:to="loc_ifrs-full_BasicEarningsLossPerShareFromDiscontinuedOperations_019e640b-7314-79f6-933e-f1d1a17e6df3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_BasicEarningsLossPerShareFromContinuingOperations_019e640b-7314-757a-8a81-a4d6c65d1a96" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_BasicEarningsLossPerShareFromContinuingOperations"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_BasicEarningsLossPerShare_019e640b-7266-7528-a5e6-4a59bf9e837e" xlink:to="loc_ifrs-full_BasicEarningsLossPerShareFromContinuingOperations_019e640b-7314-757a-8a81-a4d6c65d1a96" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossAttributableToOrdinaryEquityHoldersOfParentEntity_019e640b-7266-79d8-b0f6-1a02fa59a79e" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLossAttributableToOrdinaryEquityHoldersOfParentEntity"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossAttributableToOwnersOfParent_019e640b-7266-7817-8953-a563d5d4f092" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLossAttributableToOwnersOfParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossAttributableToOrdinaryEquityHoldersOfParentEntity_019e640b-7266-79d8-b0f6-1a02fa59a79e" xlink:to="loc_ifrs-full_ProfitLossAttributableToOwnersOfParent_019e640b-7266-7817-8953-a563d5d4f092" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_AdjustmentToProfitLossForRemunerationOfContingentlyConvertiblePreferredSecurities_019e640b-7266-7a04-aad6-5814a13b98ad" xlink:href="san-20260630.xsd#san_AdjustmentToProfitLossForRemunerationOfContingentlyConvertiblePreferredSecurities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossAttributableToOrdinaryEquityHoldersOfParentEntity_019e640b-7266-79d8-b0f6-1a02fa59a79e" xlink:to="loc_san_AdjustmentToProfitLossForRemunerationOfContingentlyConvertiblePreferredSecurities_019e640b-7266-7a04-aad6-5814a13b98ad" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/ShareholderremunerationsystemandearningspershareScheduleofdilutedearningspershareDetails" xlink:type="simple" xlink:href="san-20260630.xsd#ShareholderremunerationsystemandearningspershareScheduleofdilutedearningspershareDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/ShareholderremunerationsystemandearningspershareScheduleofdilutedearningspershareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DilutedEarningsLossPerShare_019e640b-7314-72cd-8396-93474c2792f9" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DilutedEarningsLossPerShare"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DilutedEarningsLossPerShareFromDiscontinuedOperations_019e640b-7314-77d7-a284-d3cc0fe51ba2" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DilutedEarningsLossPerShareFromDiscontinuedOperations"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_DilutedEarningsLossPerShare_019e640b-7314-72cd-8396-93474c2792f9" xlink:to="loc_ifrs-full_DilutedEarningsLossPerShareFromDiscontinuedOperations_019e640b-7314-77d7-a284-d3cc0fe51ba2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DilutedEarningsLossPerShareFromContinuingOperations_019e640b-7314-7bba-8198-9b4c9518ec47" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DilutedEarningsLossPerShareFromContinuingOperations"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_DilutedEarningsLossPerShare_019e640b-7314-72cd-8396-93474c2792f9" xlink:to="loc_ifrs-full_DilutedEarningsLossPerShareFromContinuingOperations_019e640b-7314-7bba-8198-9b4c9518ec47" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AdjustedWeightedAverageShares_019e640b-7314-7b28-9ecc-824e5db58f00" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AdjustedWeightedAverageShares"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DilutiveEffectOfShareOptionsAndShareRightsOnNumberOfOrdinaryShares_019e640b-7314-7338-96ab-aa2a9713d43d" xlink:href="san-20260630.xsd#san_DilutiveEffectOfShareOptionsAndShareRightsOnNumberOfOrdinaryShares"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AdjustedWeightedAverageShares_019e640b-7314-7b28-9ecc-824e5db58f00" xlink:to="loc_san_DilutiveEffectOfShareOptionsAndShareRightsOnNumberOfOrdinaryShares_019e640b-7314-7338-96ab-aa2a9713d43d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_WeightedAverageShares_019e640b-7314-7a33-a16c-85dd6bd9a1b6" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_WeightedAverageShares"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AdjustedWeightedAverageShares_019e640b-7314-7b28-9ecc-824e5db58f00" xlink:to="loc_ifrs-full_WeightedAverageShares_019e640b-7314-7a33-a16c-85dd6bd9a1b6" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/RemunerationandotherbenefitspaidtoBancoSantandersdirectorsandseniormanagersScheduleofremunerationofmembersoftheboardofdirectorsDetails" xlink:type="simple" xlink:href="san-20260630.xsd#RemunerationandotherbenefitspaidtoBancoSantandersdirectorsandseniormanagersScheduleofremunerationofmembersoftheboardofdirectorsDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/RemunerationandotherbenefitspaidtoBancoSantandersdirectorsandseniormanagersScheduleofremunerationofmembersoftheboardofdirectorsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_KeyManagementPersonnelCompensationShorttermEmployeeBenefits_019e640b-7314-79c7-8bce-630f5313799c" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_KeyManagementPersonnelCompensationShorttermEmployeeBenefits"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_KeyManagementPersonnelCompensationShortTermEmployeeBenefitsFixed_019e640b-7314-7e48-b575-a57dab2b3a1b" xlink:href="san-20260630.xsd#san_KeyManagementPersonnelCompensationShortTermEmployeeBenefitsFixed"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_KeyManagementPersonnelCompensationShorttermEmployeeBenefits_019e640b-7314-79c7-8bce-630f5313799c" xlink:to="loc_san_KeyManagementPersonnelCompensationShortTermEmployeeBenefitsFixed_019e640b-7314-7e48-b575-a57dab2b3a1b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_KeyManagementPersonnelCompensationShortTermEmployeeBenefitsVariable_019e640b-7314-799e-b7b6-9d06ccac85c0" xlink:href="san-20260630.xsd#san_KeyManagementPersonnelCompensationShortTermEmployeeBenefitsVariable"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_KeyManagementPersonnelCompensationShorttermEmployeeBenefits_019e640b-7314-79c7-8bce-630f5313799c" xlink:to="loc_san_KeyManagementPersonnelCompensationShortTermEmployeeBenefitsVariable_019e640b-7314-799e-b7b6-9d06ccac85c0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_KeyManagementPersonnelCompensationAttendanceFees_019e6463-dd36-741e-bb15-d0b86deda313" xlink:href="san-20260630.xsd#san_KeyManagementPersonnelCompensationAttendanceFees"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_KeyManagementPersonnelCompensationShorttermEmployeeBenefits_019e640b-7314-79c7-8bce-630f5313799c" xlink:to="loc_san_KeyManagementPersonnelCompensationAttendanceFees_019e6463-dd36-741e-bb15-d0b86deda313" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_KeyManagementPersonnelCompensationEmoluments_019e6463-dd36-7d20-8599-04c13adf4c67" xlink:href="san-20260630.xsd#san_KeyManagementPersonnelCompensationEmoluments"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_KeyManagementPersonnelCompensationShorttermEmployeeBenefits_019e640b-7314-79c7-8bce-630f5313799c" xlink:to="loc_san_KeyManagementPersonnelCompensationEmoluments_019e6463-dd36-7d20-8599-04c13adf4c67" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_KeyManagementPersonnelCompensationOtherShortTermEmployeeBenefits_019e6463-dd36-7870-a87b-68c15a952e06" xlink:href="san-20260630.xsd#san_KeyManagementPersonnelCompensationOtherShortTermEmployeeBenefits"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_KeyManagementPersonnelCompensationShorttermEmployeeBenefits_019e640b-7314-79c7-8bce-630f5313799c" xlink:to="loc_san_KeyManagementPersonnelCompensationOtherShortTermEmployeeBenefits_019e6463-dd36-7870-a87b-68c15a952e06" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/FinancialassetsDisclosureofreconciliationofchangesinlossallowanceDetails" xlink:type="simple" xlink:href="san-20260630.xsd#FinancialassetsDisclosureofreconciliationofchangesinlossallowanceDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/FinancialassetsDisclosureofreconciliationofchangesinlossallowanceDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss_019e640b-7314-7dc6-a2fd-429a646b3c9f" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ImpairmentLossRecognisedInProfitOrLoss_019e640b-7314-7ac1-86d7-203c7a5f9f90" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ImpairmentLossRecognisedInProfitOrLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss_019e640b-7314-7dc6-a2fd-429a646b3c9f" xlink:to="loc_ifrs-full_ImpairmentLossRecognisedInProfitOrLoss_019e640b-7314-7ac1-86d7-203c7a5f9f90" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReversalOfImpairmentLossRecognisedInProfitOrLoss_019e640b-7314-7a38-a739-a44d0cc051f1" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReversalOfImpairmentLossRecognisedInProfitOrLoss"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss_019e640b-7314-7dc6-a2fd-429a646b3c9f" xlink:to="loc_ifrs-full_ReversalOfImpairmentLossRecognisedInProfitOrLoss_019e640b-7314-7a38-a739-a44d0cc051f1" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/FinancialassetsScheduleofcollateralsreceivedforfinancialassetsDetails" xlink:type="simple" xlink:href="san-20260630.xsd#FinancialassetsScheduleofcollateralsreceivedforfinancialassetsDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/FinancialassetsScheduleofcollateralsreceivedforfinancialassetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_san_RealAndOtherCollateralsReceivedForFinancialAssets_019e640b-7314-773b-a9f9-0565b9be5e7d" xlink:href="san-20260630.xsd#san_RealAndOtherCollateralsReceivedForFinancialAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_RealCollateralsReceivedForFinancialAssets_019e640b-7314-7d0f-966e-41c91bd57343" xlink:href="san-20260630.xsd#san_RealCollateralsReceivedForFinancialAssets"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_RealAndOtherCollateralsReceivedForFinancialAssets_019e640b-7314-773b-a9f9-0565b9be5e7d" xlink:to="loc_san_RealCollateralsReceivedForFinancialAssets_019e640b-7314-7d0f-966e-41c91bd57343" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherThanRealCollateralsReceivedForFinancialAssets_019e640b-7314-721b-809d-2c1b0edd8d26" xlink:href="san-20260630.xsd#san_OtherThanRealCollateralsReceivedForFinancialAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_RealAndOtherCollateralsReceivedForFinancialAssets_019e640b-7314-773b-a9f9-0565b9be5e7d" xlink:to="loc_san_OtherThanRealCollateralsReceivedForFinancialAssets_019e640b-7314-721b-809d-2c1b0edd8d26" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/NoncurrentassetsheldforsaleandliabilitiesassociatedwithnoncurrentassetsheldforsaleDiscontinuedoperationsCondensedfinancialstatementsDetails" xlink:type="simple" xlink:href="san-20260630.xsd#NoncurrentassetsheldforsaleandliabilitiesassociatedwithnoncurrentassetsheldforsaleDiscontinuedoperationsCondensedfinancialstatementsDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/NoncurrentassetsheldforsaleandliabilitiesassociatedwithnoncurrentassetsheldforsaleDiscontinuedoperationsCondensedfinancialstatementsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Assets_019e640b-7314-71b3-9ce0-e24d44814a7d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashAndCashEquivalents_019e640b-7314-78b7-8dac-5b77c8b039e4" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashAndCashEquivalents"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7314-71b3-9ce0-e24d44814a7d" xlink:to="loc_ifrs-full_CashAndCashEquivalents_019e640b-7314-78b7-8dac-5b77c8b039e4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossClassifiedAsHeldForTrading_019e640b-7314-7010-b805-80085832b821" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossClassifiedAsHeldForTrading"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7314-71b3-9ce0-e24d44814a7d" xlink:to="loc_ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossClassifiedAsHeldForTrading_019e640b-7314-7010-b805-80085832b821" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinancialAssetsAtFairValueThroughOtherComprehensiveIncome_019e640b-7314-7427-a6c3-b0121ccf94ad" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FinancialAssetsAtFairValueThroughOtherComprehensiveIncome"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7314-71b3-9ce0-e24d44814a7d" xlink:to="loc_ifrs-full_FinancialAssetsAtFairValueThroughOtherComprehensiveIncome_019e640b-7314-7427-a6c3-b0121ccf94ad" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinancialAssetsAtAmortisedCost_019e640b-7314-766a-bc0c-768c93e11b81" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FinancialAssetsAtAmortisedCost"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7314-71b3-9ce0-e24d44814a7d" xlink:to="loc_ifrs-full_FinancialAssetsAtAmortisedCost_019e640b-7314-766a-bc0c-768c93e11b81" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IntangibleAssetsOtherThanGoodwill_019e640b-7314-7a76-acca-15494a66117b" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IntangibleAssetsOtherThanGoodwill"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7314-71b3-9ce0-e24d44814a7d" xlink:to="loc_ifrs-full_IntangibleAssetsOtherThanGoodwill_019e640b-7314-7a76-acca-15494a66117b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_TaxAssets_019e640b-7314-75f7-a336-22e998584367" xlink:href="san-20260630.xsd#san_TaxAssets"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7314-71b3-9ce0-e24d44814a7d" xlink:to="loc_san_TaxAssets_019e640b-7314-75f7-a336-22e998584367" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherAssets_019e640b-7314-7826-be4a-5cb7b28d9ce3" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherAssets"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-7314-71b3-9ce0-e24d44814a7d" xlink:to="loc_ifrs-full_OtherAssets_019e640b-7314-7826-be4a-5cb7b28d9ce3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7314-7e21-b6e5-d4607c67b46b" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLossBeforeTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GrossProfit_019e640b-7314-745d-b593-1ae3ea3243cf" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_GrossProfit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7314-7e21-b6e5-d4607c67b46b" xlink:to="loc_ifrs-full_GrossProfit_019e640b-7314-745d-b593-1ae3ea3243cf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_AdministrativeExpensesDepreciationAndAmortisationCost_019e640b-7314-767e-a082-461884c566da" xlink:href="san-20260630.xsd#san_AdministrativeExpensesDepreciationAndAmortisationCost"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7314-7e21-b6e5-d4607c67b46b" xlink:to="loc_san_AdministrativeExpensesDepreciationAndAmortisationCost_019e640b-7314-767e-a082-461884c566da" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss_019e640b-7314-71d7-b0f8-5592b6a3c18d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7314-7e21-b6e5-d4607c67b46b" xlink:to="loc_ifrs-full_ImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss_019e640b-7314-71d7-b0f8-5592b6a3c18d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherResultsAndProvisions_019e640b-7314-7d1c-a1f7-e58ab511a371" xlink:href="san-20260630.xsd#san_OtherResultsAndProvisions"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-7314-7e21-b6e5-d4607c67b46b" xlink:to="loc_san_OtherResultsAndProvisions_019e640b-7314-7d1c-a1f7-e58ab511a371" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_IncreaseDecreaseInCashAndCashEquivalentsAfterEffectOfForeignExchangeRatesDiscontinuedOperations_019e640b-7314-7b52-9a80-53077371311a" xlink:href="san-20260630.xsd#san_IncreaseDecreaseInCashAndCashEquivalentsAfterEffectOfForeignExchangeRatesDiscontinuedOperations"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInOperatingActivitiesDiscontinuedOperations_019e640b-7314-768e-bf9c-3b2edaa44e38" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashFlowsFromUsedInOperatingActivitiesDiscontinuedOperations"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInCashAndCashEquivalentsAfterEffectOfForeignExchangeRatesDiscontinuedOperations_019e640b-7314-7b52-9a80-53077371311a" xlink:to="loc_ifrs-full_CashFlowsFromUsedInOperatingActivitiesDiscontinuedOperations_019e640b-7314-768e-bf9c-3b2edaa44e38" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInInvestingActivitiesDiscontinuedOperations_019e640b-7314-7970-8a9c-a8088b939624" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashFlowsFromUsedInInvestingActivitiesDiscontinuedOperations"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInCashAndCashEquivalentsAfterEffectOfForeignExchangeRatesDiscontinuedOperations_019e640b-7314-7b52-9a80-53077371311a" xlink:to="loc_ifrs-full_CashFlowsFromUsedInInvestingActivitiesDiscontinuedOperations_019e640b-7314-7970-8a9c-a8088b939624" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInFinancingActivitiesDiscontinuedOperations_019e640b-7314-7303-8c69-dfc153c2a465" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashFlowsFromUsedInFinancingActivitiesDiscontinuedOperations"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInCashAndCashEquivalentsAfterEffectOfForeignExchangeRatesDiscontinuedOperations_019e640b-7314-7b52-9a80-53077371311a" xlink:to="loc_ifrs-full_CashFlowsFromUsedInFinancingActivitiesDiscontinuedOperations_019e640b-7314-7303-8c69-dfc153c2a465" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_EffectOfExchangeRateChangesOnCashAndCashEquivalents_019e640b-7314-785f-9f26-47b6b4f61faf" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_EffectOfExchangeRateChangesOnCashAndCashEquivalents"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IncreaseDecreaseInCashAndCashEquivalentsAfterEffectOfForeignExchangeRatesDiscontinuedOperations_019e640b-7314-7b52-9a80-53077371311a" xlink:to="loc_ifrs-full_EffectOfExchangeRateChangesOnCashAndCashEquivalents_019e640b-7314-785f-9f26-47b6b4f61faf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_GrossProfit_019e640b-7314-7a13-9f93-a526c20c844d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_GrossProfit"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InterestRevenueExpense_019e640b-7314-7afb-8366-e872ce58e072" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InterestRevenueExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7314-7a13-9f93-a526c20c844d" xlink:to="loc_ifrs-full_InterestRevenueExpense_019e640b-7314-7afb-8366-e872ce58e072" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_RevenueFromDividends_019e640b-7314-70ae-86c6-fcaaba54c3e0" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_RevenueFromDividends"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7314-7a13-9f93-a526c20c844d" xlink:to="loc_ifrs-full_RevenueFromDividends_019e640b-7314-70ae-86c6-fcaaba54c3e0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod_019e640b-7314-7db6-a645-e1f7b27c0c76" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7314-7a13-9f93-a526c20c844d" xlink:to="loc_ifrs-full_ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod_019e640b-7314-7db6-a645-e1f7b27c0c76" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FeeAndCommissionIncomeExpense_019e640b-7314-7e45-8546-9e8c0e778ea1" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FeeAndCommissionIncomeExpense"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7314-7a13-9f93-a526c20c844d" xlink:to="loc_ifrs-full_FeeAndCommissionIncomeExpense_019e640b-7314-7e45-8546-9e8c0e778ea1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_TradingIncomeExpense_019e640b-7314-7a4a-9954-e6471334628d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_TradingIncomeExpense"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7314-7a13-9f93-a526c20c844d" xlink:to="loc_ifrs-full_TradingIncomeExpense_019e640b-7314-7a4a-9954-e6471334628d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherOperatingIncomeExpense_019e640b-7314-7308-a2b4-7c87c0ef1063" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherOperatingIncomeExpense"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_GrossProfit_019e640b-7314-7a13-9f93-a526c20c844d" xlink:to="loc_ifrs-full_OtherOperatingIncomeExpense_019e640b-7314-7308-a2b4-7c87c0ef1063" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/EquityScheduleofothercomprehensiveincomecomponentsDetails" xlink:type="simple" xlink:href="san-20260630.xsd#EquityScheduleofothercomprehensiveincomecomponentsDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/EquityScheduleofothercomprehensiveincomecomponentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherComprehensiveIncomeItemsThatMayBeReclassifiedToProfitOrLoss_019e640b-7315-748f-8e9e-14d8e980aa14" xlink:href="san-20260630.xsd#san_OtherComprehensiveIncomeItemsThatMayBeReclassifiedToProfitOrLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReserveOfCashFlowHedges_019e640b-7315-7339-8e69-9f443cd2d012" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReserveOfCashFlowHedges"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatMayBeReclassifiedToProfitOrLoss_019e640b-7315-748f-8e9e-14d8e980aa14" xlink:to="loc_ifrs-full_ReserveOfCashFlowHedges_019e640b-7315-7339-8e69-9f443cd2d012" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherReservesOtherComprehensiveIncomeBeforeTaxHedgingInstrumentsNotDesignated_019e640b-7315-7efa-b509-6570104233a2" xlink:href="san-20260630.xsd#san_OtherReservesOtherComprehensiveIncomeBeforeTaxHedgingInstrumentsNotDesignated"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatMayBeReclassifiedToProfitOrLoss_019e640b-7315-748f-8e9e-14d8e980aa14" xlink:to="loc_san_OtherReservesOtherComprehensiveIncomeBeforeTaxHedgingInstrumentsNotDesignated_019e640b-7315-7efa-b509-6570104233a2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReserveOfGainsAndLossesOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome_019e640b-7315-76cb-b039-432812d2d04a" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReserveOfGainsAndLossesOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatMayBeReclassifiedToProfitOrLoss_019e640b-7315-748f-8e9e-14d8e980aa14" xlink:to="loc_ifrs-full_ReserveOfGainsAndLossesOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome_019e640b-7315-76cb-b039-432812d2d04a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReserveOfGainsAndLossesOnHedgingInstrumentsThatHedgeInvestmentsInEquityInstruments_019e640b-7315-7ad0-90d6-f8055f44e9d6" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReserveOfGainsAndLossesOnHedgingInstrumentsThatHedgeInvestmentsInEquityInstruments"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatMayBeReclassifiedToProfitOrLoss_019e640b-7315-748f-8e9e-14d8e980aa14" xlink:to="loc_ifrs-full_ReserveOfGainsAndLossesOnHedgingInstrumentsThatHedgeInvestmentsInEquityInstruments_019e640b-7315-7ad0-90d6-f8055f44e9d6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_AmountRecognisedInOtherComprehensiveIncomeAndSubjectToReclassificationToProfitOrLossRelatingToInvestmentsInAssociatedEntities_019e640b-7315-705c-90f0-bd38d358e613" xlink:href="san-20260630.xsd#san_AmountRecognisedInOtherComprehensiveIncomeAndSubjectToReclassificationToProfitOrLossRelatingToInvestmentsInAssociatedEntities"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatMayBeReclassifiedToProfitOrLoss_019e640b-7315-748f-8e9e-14d8e980aa14" xlink:to="loc_san_AmountRecognisedInOtherComprehensiveIncomeAndSubjectToReclassificationToProfitOrLossRelatingToInvestmentsInAssociatedEntities_019e640b-7315-705c-90f0-bd38d358e613" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReserveOfExchangeDifferencesOnTranslation_019e640b-7315-7cf9-8857-376347a3679d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReserveOfExchangeDifferencesOnTranslation"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatMayBeReclassifiedToProfitOrLoss_019e640b-7315-748f-8e9e-14d8e980aa14" xlink:to="loc_ifrs-full_ReserveOfExchangeDifferencesOnTranslation_019e640b-7315-7cf9-8857-376347a3679d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherReservesNonCurrentAssetsHeldForSaleThatMayBeReclassifiedToProfitOrLossNetOfTax_019e640b-7315-7089-8c8d-cd7691614568" xlink:href="san-20260630.xsd#san_OtherReservesNonCurrentAssetsHeldForSaleThatMayBeReclassifiedToProfitOrLossNetOfTax"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatMayBeReclassifiedToProfitOrLoss_019e640b-7315-748f-8e9e-14d8e980aa14" xlink:to="loc_san_OtherReservesNonCurrentAssetsHeldForSaleThatMayBeReclassifiedToProfitOrLossNetOfTax_019e640b-7315-7089-8c8d-cd7691614568" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss_019e640b-7314-7c32-a9da-ec464e95447c" xlink:href="san-20260630.xsd#san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReserveOfRemeasurementsOfDefinedBenefitPlans_019e640b-7314-768c-979f-66a8dd873069" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReserveOfRemeasurementsOfDefinedBenefitPlans"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss_019e640b-7314-7c32-a9da-ec464e95447c" xlink:to="loc_ifrs-full_ReserveOfRemeasurementsOfDefinedBenefitPlans_019e640b-7314-768c-979f-66a8dd873069" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherReservesNoncurrentAssetsHeldForSaleNotReclassifiedToProfitOrLoss_019e640b-7314-704a-bf9f-7c117fdc85e3" xlink:href="san-20260630.xsd#san_OtherReservesNoncurrentAssetsHeldForSaleNotReclassifiedToProfitOrLoss"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss_019e640b-7314-7c32-a9da-ec464e95447c" xlink:to="loc_san_OtherReservesNoncurrentAssetsHeldForSaleNotReclassifiedToProfitOrLoss_019e640b-7314-704a-bf9f-7c117fdc85e3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_AmountRecognisedInOtherComprehensiveIncomeAndAccumulatedInEquityRelatingToInvestmentsInAssociatedEntities_019e640b-7314-7c9c-92f2-2253795337ef" xlink:href="san-20260630.xsd#san_AmountRecognisedInOtherComprehensiveIncomeAndAccumulatedInEquityRelatingToInvestmentsInAssociatedEntities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss_019e640b-7314-7c32-a9da-ec464e95447c" xlink:to="loc_san_AmountRecognisedInOtherComprehensiveIncomeAndAccumulatedInEquityRelatingToInvestmentsInAssociatedEntities_019e640b-7314-7c9c-92f2-2253795337ef" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherValuationAdjustmentsNotReclassifiedToProfitOrLossNetOfTax_019e640b-7314-7476-b7f9-8f84bcd50767" xlink:href="san-20260630.xsd#san_OtherValuationAdjustmentsNotReclassifiedToProfitOrLossNetOfTax"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss_019e640b-7314-7c32-a9da-ec464e95447c" xlink:to="loc_san_OtherValuationAdjustmentsNotReclassifiedToProfitOrLossNetOfTax_019e640b-7314-7476-b7f9-8f84bcd50767" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReserveOfGainsAndLossesFromInvestmentsInEquityInstruments_019e640b-7314-753c-a367-40c184589ee9" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReserveOfGainsAndLossesFromInvestmentsInEquityInstruments"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss_019e640b-7314-7c32-a9da-ec464e95447c" xlink:to="loc_ifrs-full_ReserveOfGainsAndLossesFromInvestmentsInEquityInstruments_019e640b-7314-753c-a367-40c184589ee9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_HedgeIneffectivenessMeasuredAtFairValueThroughOtherComprehensiveIncome_019e640b-7314-7f8a-9b1b-aebcb9b15730" xlink:href="san-20260630.xsd#san_HedgeIneffectivenessMeasuredAtFairValueThroughOtherComprehensiveIncome"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss_019e640b-7314-7c32-a9da-ec464e95447c" xlink:to="loc_san_HedgeIneffectivenessMeasuredAtFairValueThroughOtherComprehensiveIncome_019e640b-7314-7f8a-9b1b-aebcb9b15730" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherReservesOtherComprehensiveIncomeBeforeTaxGainsLossesOnHedgedItem_019e640b-7314-7073-922a-b75c2dc6877c" xlink:href="san-20260630.xsd#san_OtherReservesOtherComprehensiveIncomeBeforeTaxGainsLossesOnHedgedItem"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss_019e640b-7314-7c32-a9da-ec464e95447c" xlink:to="loc_san_OtherReservesOtherComprehensiveIncomeBeforeTaxGainsLossesOnHedgedItem_019e640b-7314-7073-922a-b75c2dc6877c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherReservesOtherComprehensiveIncomeBeforeTaxGainsLossesOnHedgingInstrument_019e640b-7314-7995-a941-5c846c81869c" xlink:href="san-20260630.xsd#san_OtherReservesOtherComprehensiveIncomeBeforeTaxGainsLossesOnHedgingInstrument"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss_019e640b-7314-7c32-a9da-ec464e95447c" xlink:to="loc_san_OtherReservesOtherComprehensiveIncomeBeforeTaxGainsLossesOnHedgingInstrument_019e640b-7314-7995-a941-5c846c81869c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReserveOfChangeInFairValueOfFinancialLiabilityAttributableToChangeInCreditRiskOfLiability_019e640b-7314-7274-8f3f-2e2cc6cda71b" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReserveOfChangeInFairValueOfFinancialLiabilityAttributableToChangeInCreditRiskOfLiability"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_OtherComprehensiveIncomeItemsThatWillNotBeReclassifiedToProfitOrLoss_019e640b-7314-7c32-a9da-ec464e95447c" xlink:to="loc_ifrs-full_ReserveOfChangeInFairValueOfFinancialLiabilityAttributableToChangeInCreditRiskOfLiability_019e640b-7314-7274-8f3f-2e2cc6cda71b" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/EquityScheduleofchangesinfairvalueofequityinstrumentsthatwillnotbereclassifiedDetails" xlink:type="simple" xlink:href="san-20260630.xsd#EquityScheduleofchangesinfairvalueofequityinstrumentsthatwillnotbereclassifiedDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/EquityScheduleofchangesinfairvalueofequityinstrumentsthatwillnotbereclassifiedDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReserveOfGainsAndLossesFromInvestmentsInEquityInstruments_019e640b-7315-7ae5-a348-31fe4846dd7b" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReserveOfGainsAndLossesFromInvestmentsInEquityInstruments"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ReserveOfGainsAndLossesFromInvestmentInEquityInstrumentsAccumulatedGains_019e640b-7315-78d4-9b65-ce66ae3e74a3" xlink:href="san-20260630.xsd#san_ReserveOfGainsAndLossesFromInvestmentInEquityInstrumentsAccumulatedGains"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ReserveOfGainsAndLossesFromInvestmentsInEquityInstruments_019e640b-7315-7ae5-a348-31fe4846dd7b" xlink:to="loc_san_ReserveOfGainsAndLossesFromInvestmentInEquityInstrumentsAccumulatedGains_019e640b-7315-78d4-9b65-ce66ae3e74a3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ReserveOfGainsAndLossesFromInvestmentInEquityInstrumentsAccumulatedLosses_019e640b-7315-7fde-b75e-7b07dce64a71" xlink:href="san-20260630.xsd#san_ReserveOfGainsAndLossesFromInvestmentInEquityInstrumentsAccumulatedLosses"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ReserveOfGainsAndLossesFromInvestmentsInEquityInstruments_019e640b-7315-7ae5-a348-31fe4846dd7b" xlink:to="loc_san_ReserveOfGainsAndLossesFromInvestmentInEquityInstrumentsAccumulatedLosses_019e640b-7315-7fde-b75e-7b07dce64a71" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/EquityScheduleofothercomprehensiveincomethatmaybereclassifiedtoprofitorlossbytypeofinstrumentandgeographicaloriginoftheissuerDetails" xlink:type="simple" xlink:href="san-20260630.xsd#EquityScheduleofothercomprehensiveincomethatmaybereclassifiedtoprofitorlossbytypeofinstrumentandgeographicaloriginoftheissuerDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/EquityScheduleofothercomprehensiveincomethatmaybereclassifiedtoprofitorlossbytypeofinstrumentandgeographicaloriginoftheissuerDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ReserveOfGainsAndLossesOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome_019e640b-7315-7f1d-9776-ceeb0e5069bc" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ReserveOfGainsAndLossesOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ReserveOfLossesOnRemeasuringFinancialAssetsAtFairValueWithChangesInOtherComprehensiveIncome_019e640b-7315-7cd8-a8fd-1aefeb63def5" xlink:href="san-20260630.xsd#san_ReserveOfLossesOnRemeasuringFinancialAssetsAtFairValueWithChangesInOtherComprehensiveIncome"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ReserveOfGainsAndLossesOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome_019e640b-7315-7f1d-9776-ceeb0e5069bc" xlink:to="loc_san_ReserveOfLossesOnRemeasuringFinancialAssetsAtFairValueWithChangesInOtherComprehensiveIncome_019e640b-7315-7cd8-a8fd-1aefeb63def5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ReserveOfGainsOnRemeasuringFinancialAssetsAtFairValueWithChangesInOtherComprehensiveIncome_019e640b-7315-76be-a966-bac9bc66f0cb" xlink:href="san-20260630.xsd#san_ReserveOfGainsOnRemeasuringFinancialAssetsAtFairValueWithChangesInOtherComprehensiveIncome"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ReserveOfGainsAndLossesOnFinancialAssetsMeasuredAtFairValueThroughOtherComprehensiveIncome_019e640b-7315-7f1d-9776-ceeb0e5069bc" xlink:to="loc_san_ReserveOfGainsOnRemeasuringFinancialAssetsAtFairValueWithChangesInOtherComprehensiveIncome_019e640b-7315-76be-a966-bac9bc66f0cb" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/RelatedpartiesDetails" xlink:type="simple" xlink:href="san-20260630.xsd#RelatedpartiesDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/RelatedpartiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AmountsPayableRelatedPartyTransactions_019e640b-7315-711d-aa31-2fc2c53fc98d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AmountsPayableRelatedPartyTransactions"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_PayableToRelatedPartyAttributableToLoansAndCreditsReceived_019e640b-7315-7260-9e1a-4c7e34bfabc2" xlink:href="san-20260630.xsd#san_PayableToRelatedPartyAttributableToLoansAndCreditsReceived"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AmountsPayableRelatedPartyTransactions_019e640b-7315-711d-aa31-2fc2c53fc98d" xlink:to="loc_san_PayableToRelatedPartyAttributableToLoansAndCreditsReceived_019e640b-7315-7260-9e1a-4c7e34bfabc2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_PayableToRelatedPartyOther_019e640b-7315-7518-b297-86f5c75169d4" xlink:href="san-20260630.xsd#san_PayableToRelatedPartyOther"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AmountsPayableRelatedPartyTransactions_019e640b-7315-711d-aa31-2fc2c53fc98d" xlink:to="loc_san_PayableToRelatedPartyOther_019e640b-7315-7518-b297-86f5c75169d4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_PayableToRelatedPartyAttributableToSuppliersAndCreditorsGranted_019e640b-7315-70b3-b881-844621d119a7" xlink:href="san-20260630.xsd#san_PayableToRelatedPartyAttributableToSuppliersAndCreditorsGranted"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AmountsPayableRelatedPartyTransactions_019e640b-7315-711d-aa31-2fc2c53fc98d" xlink:to="loc_san_PayableToRelatedPartyAttributableToSuppliersAndCreditorsGranted_019e640b-7315-70b3-b881-844621d119a7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_TotalIncomeRelatedPartyTransactions_019e640b-7315-7b95-a8f2-4eac685869ba" xlink:href="san-20260630.xsd#san_TotalIncomeRelatedPartyTransactions"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_FinanceIncomeRelatedPartyTransactions_019e640b-7315-7b3e-9db8-329e3142b0e6" xlink:href="san-20260630.xsd#san_FinanceIncomeRelatedPartyTransactions"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TotalIncomeRelatedPartyTransactions_019e640b-7315-7b95-a8f2-4eac685869ba" xlink:to="loc_san_FinanceIncomeRelatedPartyTransactions_019e640b-7315-7b3e-9db8-329e3142b0e6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_SaleOfStocksRelatedPartyTransactions_019e640b-7315-7605-ab93-f3d90c758a0a" xlink:href="san-20260630.xsd#san_SaleOfStocksRelatedPartyTransactions"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TotalIncomeRelatedPartyTransactions_019e640b-7315-7b95-a8f2-4eac685869ba" xlink:to="loc_san_SaleOfStocksRelatedPartyTransactions_019e640b-7315-7605-ab93-f3d90c758a0a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherIncomeRelatedPartyTransactions_019e640b-7315-7219-bd4f-d2147ed71ac3" xlink:href="san-20260630.xsd#san_OtherIncomeRelatedPartyTransactions"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TotalIncomeRelatedPartyTransactions_019e640b-7315-7b95-a8f2-4eac685869ba" xlink:to="loc_san_OtherIncomeRelatedPartyTransactions_019e640b-7315-7219-bd4f-d2147ed71ac3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DividendsReceivedRelatedPartyTransactions_019e640b-7315-7bea-8c87-75472a98d90a" xlink:href="san-20260630.xsd#san_DividendsReceivedRelatedPartyTransactions"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TotalIncomeRelatedPartyTransactions_019e640b-7315-7b95-a8f2-4eac685869ba" xlink:to="loc_san_DividendsReceivedRelatedPartyTransactions_019e640b-7315-7bea-8c87-75472a98d90a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_RevenueFromRenderingOfServicesRelatedPartyTransactions_019e640b-7315-7c3e-99fa-0b5ef856a71c" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_RevenueFromRenderingOfServicesRelatedPartyTransactions"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TotalIncomeRelatedPartyTransactions_019e640b-7315-7b95-a8f2-4eac685869ba" xlink:to="loc_ifrs-full_RevenueFromRenderingOfServicesRelatedPartyTransactions_019e640b-7315-7c3e-99fa-0b5ef856a71c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_TotalExpensesRelatedPartyTransactions_019e640b-7315-737d-862e-e389831675b7" xlink:href="san-20260630.xsd#san_TotalExpensesRelatedPartyTransactions"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_FinanceCostsRelatedPartyTransactions_019e640b-7315-75d0-b367-f954b9efd60f" xlink:href="san-20260630.xsd#san_FinanceCostsRelatedPartyTransactions"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TotalExpensesRelatedPartyTransactions_019e640b-7315-737d-862e-e389831675b7" xlink:to="loc_san_FinanceCostsRelatedPartyTransactions_019e640b-7315-75d0-b367-f954b9efd60f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_LeasesRelatedPartyTransactions_019e640b-7315-7ea6-9507-ca3a5677d906" xlink:href="san-20260630.xsd#san_LeasesRelatedPartyTransactions"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TotalExpensesRelatedPartyTransactions_019e640b-7315-737d-862e-e389831675b7" xlink:to="loc_san_LeasesRelatedPartyTransactions_019e640b-7315-7ea6-9507-ca3a5677d906" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherExpensesRelatedPartyTransactions_019e640b-7315-70bd-9729-1876e2e0e0e1" xlink:href="san-20260630.xsd#san_OtherExpensesRelatedPartyTransactions"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TotalExpensesRelatedPartyTransactions_019e640b-7315-737d-862e-e389831675b7" xlink:to="loc_san_OtherExpensesRelatedPartyTransactions_019e640b-7315-70bd-9729-1876e2e0e0e1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_PurchaseOfStocksRelatedPartyTransactions_019e640b-7315-7c58-855e-369204f404d9" xlink:href="san-20260630.xsd#san_PurchaseOfStocksRelatedPartyTransactions"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TotalExpensesRelatedPartyTransactions_019e640b-7315-737d-862e-e389831675b7" xlink:to="loc_san_PurchaseOfStocksRelatedPartyTransactions_019e640b-7315-7c58-855e-369204f404d9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ServicesReceivedRelatedPartyTransactions_019e640b-7315-7fc7-b13e-44c73a9b5cb6" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ServicesReceivedRelatedPartyTransactions"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_TotalExpensesRelatedPartyTransactions_019e640b-7315-737d-862e-e389831675b7" xlink:to="loc_ifrs-full_ServicesReceivedRelatedPartyTransactions_019e640b-7315-7fc7-b13e-44c73a9b5cb6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_AmountsReceivableRelatedPartyTransactions_019e640b-7315-714c-a447-4a58fa19e777" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_AmountsReceivableRelatedPartyTransactions"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ReceivableFromRelatedPartyAttributableToLoansAndCreditsGranted_019e640b-7315-73f8-8bc8-74b1db1c0af9" xlink:href="san-20260630.xsd#san_ReceivableFromRelatedPartyAttributableToLoansAndCreditsGranted"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AmountsReceivableRelatedPartyTransactions_019e640b-7315-714c-a447-4a58fa19e777" xlink:to="loc_san_ReceivableFromRelatedPartyAttributableToLoansAndCreditsGranted_019e640b-7315-73f8-8bc8-74b1db1c0af9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ReceivableFromRelatedPartyOther_019e640b-7315-7b17-94c0-643e88f91bd7" xlink:href="san-20260630.xsd#san_ReceivableFromRelatedPartyOther"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AmountsReceivableRelatedPartyTransactions_019e640b-7315-714c-a447-4a58fa19e777" xlink:to="loc_san_ReceivableFromRelatedPartyOther_019e640b-7315-7b17-94c0-643e88f91bd7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_ReceivableFromRelatedPartyAttributableToCustomersAndCommercialDebtors_019e640b-7315-763d-aa6a-1802d12de1b9" xlink:href="san-20260630.xsd#san_ReceivableFromRelatedPartyAttributableToCustomersAndCommercialDebtors"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_AmountsReceivableRelatedPartyTransactions_019e640b-7315-714c-a447-4a58fa19e777" xlink:to="loc_san_ReceivableFromRelatedPartyAttributableToCustomersAndCommercialDebtors_019e640b-7315-763d-aa6a-1802d12de1b9" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/OtherdisclosuresDisclosureofcapitalratioDetails" xlink:type="simple" xlink:href="san-20260630.xsd#OtherdisclosuresDisclosureofcapitalratioDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/OtherdisclosuresDisclosureofcapitalratioDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_san_IfrsCapitalToRiskWeightedAssets_019e640b-73d7-7a8a-a891-ff3be54368b2" xlink:href="san-20260630.xsd#san_IfrsCapitalToRiskWeightedAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_CommonEquityTierTwoCapitalRatio_019e640b-73d7-70de-bef7-169ef68e37df" xlink:href="san-20260630.xsd#san_CommonEquityTierTwoCapitalRatio"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IfrsCapitalToRiskWeightedAssets_019e640b-73d7-7a8a-a891-ff3be54368b2" xlink:to="loc_san_CommonEquityTierTwoCapitalRatio_019e640b-73d7-70de-bef7-169ef68e37df" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_IfrsTierOneRiskBasedCapitalToRiskWeightedAssets_019e640b-73d7-7c5e-afea-c05bf6b6702e" xlink:href="san-20260630.xsd#san_IfrsTierOneRiskBasedCapitalToRiskWeightedAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IfrsCapitalToRiskWeightedAssets_019e640b-73d7-7a8a-a891-ff3be54368b2" xlink:to="loc_san_IfrsTierOneRiskBasedCapitalToRiskWeightedAssets_019e640b-73d7-7c5e-afea-c05bf6b6702e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_IfrsTierOneRiskBasedCapitalToRiskWeightedAssets_019e640b-73d7-749a-909f-88b0a594fda7" xlink:href="san-20260630.xsd#san_IfrsTierOneRiskBasedCapitalToRiskWeightedAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_TierOneCapitalInExcessOfCommonEquityTierOneCapitalPercentageOfRiskWeightedAssets_019e640b-73d7-7390-b609-fa6ceb413082" xlink:href="san-20260630.xsd#san_TierOneCapitalInExcessOfCommonEquityTierOneCapitalPercentageOfRiskWeightedAssets"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IfrsTierOneRiskBasedCapitalToRiskWeightedAssets_019e640b-73d7-749a-909f-88b0a594fda7" xlink:to="loc_san_TierOneCapitalInExcessOfCommonEquityTierOneCapitalPercentageOfRiskWeightedAssets_019e640b-73d7-7390-b609-fa6ceb413082" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_IFRSCommonEquityTierOneCapitalRatio_019e640b-73d7-7f78-a87f-7726e92bb277" xlink:href="san-20260630.xsd#san_IFRSCommonEquityTierOneCapitalRatio"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_IfrsTierOneRiskBasedCapitalToRiskWeightedAssets_019e640b-73d7-749a-909f-88b0a594fda7" xlink:to="loc_san_IFRSCommonEquityTierOneCapitalRatio_019e640b-73d7-7f78-a87f-7726e92bb277" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/AdditionaldisclosurerequirementsCondensedBalanceSheetsDetails" xlink:type="simple" xlink:href="san-20260630.xsd#AdditionaldisclosurerequirementsCondensedBalanceSheetsDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/AdditionaldisclosurerequirementsCondensedBalanceSheetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Equity_019e640b-73d8-74bb-b748-4b69fafa38db" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Equity"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_IssuedCapital_019e640b-73d8-79a4-bdc3-c62d9afd743e" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_IssuedCapital"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_019e640b-73d8-74bb-b748-4b69fafa38db" xlink:to="loc_ifrs-full_IssuedCapital_019e640b-73d8-79a4-bdc3-c62d9afd743e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_RetainedEarningsAndOtherReserves_019e640b-73d8-730c-80d0-6c3b4e85d794" xlink:href="san-20260630.xsd#san_RetainedEarningsAndOtherReserves"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Equity_019e640b-73d8-74bb-b748-4b69fafa38db" xlink:to="loc_san_RetainedEarningsAndOtherReserves_019e640b-73d8-730c-80d0-6c3b4e85d794" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Assets_019e640b-73d8-77eb-a93a-653db855adf5" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashAndBankBalancesAtCentralBanks_019e640b-73d8-7bc0-9129-9e7f25831fc3" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashAndBankBalancesAtCentralBanks"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-73d8-77eb-a93a-653db855adf5" xlink:to="loc_ifrs-full_CashAndBankBalancesAtCentralBanks_019e640b-73d8-7bc0-9129-9e7f25831fc3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossClassifiedAsHeldForTrading_019e640b-73d8-7cdc-831d-26bc784db6a5" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossClassifiedAsHeldForTrading"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-73d8-77eb-a93a-653db855adf5" xlink:to="loc_ifrs-full_FinancialAssetsAtFairValueThroughProfitOrLossClassifiedAsHeldForTrading_019e640b-73d8-7cdc-831d-26bc784db6a5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_FinancialAssets_019e640b-73d8-7949-bc15-b88e92124af9" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_FinancialAssets"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-73d8-77eb-a93a-653db855adf5" xlink:to="loc_ifrs-full_FinancialAssets_019e640b-73d8-7949-bc15-b88e92124af9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InvestmentsInSubsidiariesJointVenturesAndAssociates_019e640b-73d8-7e09-9352-5c8b022740d2" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InvestmentsInSubsidiariesJointVenturesAndAssociates"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-73d8-77eb-a93a-653db855adf5" xlink:to="loc_ifrs-full_InvestmentsInSubsidiariesJointVenturesAndAssociates_019e640b-73d8-7e09-9352-5c8b022740d2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_PropertyPlantAndEquipmentIncludingRightofuseAssets_019e640b-73d8-7896-8a1c-500d78e025b5" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_PropertyPlantAndEquipmentIncludingRightofuseAssets"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-73d8-77eb-a93a-653db855adf5" xlink:to="loc_ifrs-full_PropertyPlantAndEquipmentIncludingRightofuseAssets_019e640b-73d8-7896-8a1c-500d78e025b5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherAssets_019e640b-73d8-7cb9-80ba-08e7b7a7aef9" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherAssets"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-73d8-77eb-a93a-653db855adf5" xlink:to="loc_ifrs-full_OtherAssets_019e640b-73d8-7cb9-80ba-08e7b7a7aef9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_InvestmentSecurities_019e640b-73d8-7c6d-942b-2ff300b752a3" xlink:href="san-20260630.xsd#san_InvestmentSecurities"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Assets_019e640b-73d8-77eb-a93a-653db855adf5" xlink:to="loc_san_InvestmentSecurities_019e640b-73d8-7c6d-942b-2ff300b752a3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Liabilities_019e640b-73d8-7930-a161-b62b39b11467" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Liabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_DepositLiability_019e640b-73d8-73df-905b-63d96a88f1f7" xlink:href="san-20260630.xsd#san_DepositLiability"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Liabilities_019e640b-73d8-7930-a161-b62b39b11467" xlink:to="loc_san_DepositLiability_019e640b-73d8-73df-905b-63d96a88f1f7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Borrowings_019e640b-73d8-77f4-8302-013354e5b5f5" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Borrowings"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Liabilities_019e640b-73d8-7930-a161-b62b39b11467" xlink:to="loc_ifrs-full_Borrowings_019e640b-73d8-77f4-8302-013354e5b5f5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherLiabilities_019e640b-73d8-7441-8fd0-d45af5328b33" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherLiabilities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Liabilities_019e640b-73d8-7930-a161-b62b39b11467" xlink:to="loc_ifrs-full_OtherLiabilities_019e640b-73d8-7441-8fd0-d45af5328b33" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_Borrowings_019e640b-73d8-794f-9bf9-8fe49e440cbb" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_Borrowings"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ShorttermBorrowings_019e640b-73d8-7356-a099-40f90c86898a" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ShorttermBorrowings"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Borrowings_019e640b-73d8-794f-9bf9-8fe49e440cbb" xlink:to="loc_ifrs-full_ShorttermBorrowings_019e640b-73d8-7356-a099-40f90c86898a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_LongtermBorrowings_019e640b-73d8-755e-947a-ef39b7fba5e0" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_LongtermBorrowings"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_Borrowings_019e640b-73d8-794f-9bf9-8fe49e440cbb" xlink:to="loc_ifrs-full_LongtermBorrowings_019e640b-73d8-755e-947a-ef39b7fba5e0" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/AdditionaldisclosurerequirementsCondensedStatementsofIncomeDetails" xlink:type="simple" xlink:href="san-20260630.xsd#AdditionaldisclosurerequirementsCondensedStatementsofIncomeDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/AdditionaldisclosurerequirementsCondensedStatementsofIncomeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_san_NetInterestAndDividendIncomeExpenseAfterProvisionForCreditLosses_019e640b-73d8-7b66-a299-231d873aa062" xlink:href="san-20260630.xsd#san_NetInterestAndDividendIncomeExpenseAfterProvisionForCreditLosses"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss_019e640b-73d8-73ac-97c3-9de6eb589ee6" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_NetInterestAndDividendIncomeExpenseAfterProvisionForCreditLosses_019e640b-73d8-7b66-a299-231d873aa062" xlink:to="loc_ifrs-full_ImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss_019e640b-73d8-73ac-97c3-9de6eb589ee6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_InterestIncomeExpenseNetPlusDividendsFromAffiliates_019e640b-73d8-7ba2-809b-11724b8e8604" xlink:href="san-20260630.xsd#san_InterestIncomeExpenseNetPlusDividendsFromAffiliates"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_NetInterestAndDividendIncomeExpenseAfterProvisionForCreditLosses_019e640b-73d8-7b66-a299-231d873aa062" xlink:to="loc_san_InterestIncomeExpenseNetPlusDividendsFromAffiliates_019e640b-73d8-7ba2-809b-11724b8e8604" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_InterestIncomeExpenseNetPlusDividendsFromAffiliates_019e640b-73d8-7f1b-b5da-913cffb33232" xlink:href="san-20260630.xsd#san_InterestIncomeExpenseNetPlusDividendsFromAffiliates"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_RevenueFromInterest_019e640b-73d8-76d4-91cf-8ab3de98a17d" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_RevenueFromInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_InterestIncomeExpenseNetPlusDividendsFromAffiliates_019e640b-73d8-7f1b-b5da-913cffb33232" xlink:to="loc_ifrs-full_RevenueFromInterest_019e640b-73d8-76d4-91cf-8ab3de98a17d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_InterestExpense_019e640b-73d8-74ea-9950-6f2ef4f197d8" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_InterestExpense"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_san_InterestIncomeExpenseNetPlusDividendsFromAffiliates_019e640b-73d8-7f1b-b5da-913cffb33232" xlink:to="loc_ifrs-full_InterestExpense_019e640b-73d8-74ea-9950-6f2ef4f197d8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProfitLossBeforeTax_019e640b-73d8-7328-848b-1d827d532a24" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProfitLossBeforeTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_NetInterestAndDividendIncomeExpenseAfterProvisionForCreditLosses_019e640b-73d8-730e-bb65-7b88c7c7162b" xlink:href="san-20260630.xsd#san_NetInterestAndDividendIncomeExpenseAfterProvisionForCreditLosses"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-73d8-7328-848b-1d827d532a24" xlink:to="loc_san_NetInterestAndDividendIncomeExpenseAfterProvisionForCreditLosses_019e640b-73d8-730e-bb65-7b88c7c7162b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherOperatingExpense_019e640b-73d8-7782-aa4f-2c093e771099" xlink:href="san-20260630.xsd#san_OtherOperatingExpense"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-73d8-7328-848b-1d827d532a24" xlink:to="loc_san_OtherOperatingExpense_019e640b-73d8-7782-aa4f-2c093e771099" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_OtherOperatingIncome1_019e640b-73d8-71d9-a3d0-fc21cbaa4195" xlink:href="san-20260630.xsd#san_OtherOperatingIncome1"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_ProfitLossBeforeTax_019e640b-73d8-7328-848b-1d827d532a24" xlink:to="loc_san_OtherOperatingIncome1_019e640b-73d8-71d9-a3d0-fc21cbaa4195" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.santander.com/role/AdditionaldisclosurerequirementsCondensedCashFlowStatementsDetails" xlink:type="simple" xlink:href="san-20260630.xsd#AdditionaldisclosurerequirementsCondensedCashFlowStatementsDetails"/>
  <link:calculationLink xlink:role="http://www.santander.com/role/AdditionaldisclosurerequirementsCondensedCashFlowStatementsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-73d8-7fb7-b494-d13d3a0d2f55" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_CashFlowsFromUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_IssuanceRedemptionOfTreasuryShares_019e640b-73d8-774a-9ceb-f664608e79ae" xlink:href="san-20260630.xsd#san_IssuanceRedemptionOfTreasuryShares"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-73d8-7fb7-b494-d13d3a0d2f55" xlink:to="loc_san_IssuanceRedemptionOfTreasuryShares_019e640b-73d8-774a-9ceb-f664608e79ae" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromIssueOfBondsNotesAndDebentures_019e640b-73d8-7b8b-90c0-10f81569ded6" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProceedsFromIssueOfBondsNotesAndDebentures"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-73d8-7fb7-b494-d13d3a0d2f55" xlink:to="loc_ifrs-full_ProceedsFromIssueOfBondsNotesAndDebentures_019e640b-73d8-7b8b-90c0-10f81569ded6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_san_PaymentsToAcquireEntityShares_019e640b-73d8-7a97-ab50-f67485862126" xlink:href="san-20260630.xsd#san_PaymentsToAcquireEntityShares"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-73d8-7fb7-b494-d13d3a0d2f55" xlink:to="loc_san_PaymentsToAcquireEntityShares_019e640b-73d8-7a97-ab50-f67485862126" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_DividendsPaidClassifiedAsFinancingActivities_019e640b-73d8-7b32-87f4-b1b6a49ec42f" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_DividendsPaidClassifiedAsFinancingActivities"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-73d8-7fb7-b494-d13d3a0d2f55" xlink:to="loc_ifrs-full_DividendsPaidClassifiedAsFinancingActivities_019e640b-73d8-7b32-87f4-b1b6a49ec42f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_RepaymentsOfBondsNotesAndDebentures_019e640b-73d8-7add-a3be-9aaa4db2654c" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_RepaymentsOfBondsNotesAndDebentures"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-73d8-7fb7-b494-d13d3a0d2f55" xlink:to="loc_ifrs-full_RepaymentsOfBondsNotesAndDebentures_019e640b-73d8-7add-a3be-9aaa4db2654c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_OtherInflowsOutflowsOfCashClassifiedAsFinancingActivities_019e640b-73d8-71e0-a39e-0d59f316cdfb" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_OtherInflowsOutflowsOfCashClassifiedAsFinancingActivities"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-73d8-7fb7-b494-d13d3a0d2f55" xlink:to="loc_ifrs-full_OtherInflowsOutflowsOfCashClassifiedAsFinancingActivities_019e640b-73d8-71e0-a39e-0d59f316cdfb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromIssuingShares_019e640b-73d8-77c5-bfce-0fe55227e3d5" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProceedsFromIssuingShares"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-73d8-7fb7-b494-d13d3a0d2f55" xlink:to="loc_ifrs-full_ProceedsFromIssuingShares_019e640b-73d8-77c5-bfce-0fe55227e3d5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ifrs-full_ProceedsFromSaleOrIssueOfTreasuryShares_019e640b-73d8-7a0a-8237-b49f9dd0b4e3" xlink:href="https://xbrl.ifrs.org/taxonomy/2025-03-27/full_ifrs/full_ifrs-cor_2025-03-27.xsd#ifrs-full_ProceedsFromSaleOrIssueOfTreasuryShares"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="https://xbrl.org/2023/arcrole/summation-item" xlink:from="loc_ifrs-full_CashFlowsFromUsedInFinancingActivities_019e640b-73d8-7fb7-b494-d13d3a0d2f55" xlink:to="loc_ifrs-full_ProceedsFromSaleOrIssueOfTreasuryShares_019e640b-73d8-7a0a-8237-b49f9dd0b4e3" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
