S-1 S-1/A EX-FILING FEES 333-297489 0001585608 Jaguar Health, Inc. N/A N/A 0001585608 2026-07-24 2026-07-24 0001585608 1 2026-07-24 2026-07-24 0001585608 2 2026-07-24 2026-07-24 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-1

Jaguar Health, Inc.

Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Fees to be Paid 1 Equity Voting common stock, par value $0.0001 per share 457(a) 200,000 $ 1.30 $ 260,000.00 0.0001381 $ 35.91
Fees Previously Paid 2 Equity Voting common stock, par value $0.0001 per share 457(a) 40,800,000 $ 2.20 $ 89,760,000.00 $ 12,395.86
Carry Forward Securities
Carry Forward Securities

Total Offering Amounts:

$ 90,020,000.00

$ 12,431.77

Total Fees Previously Paid:

$ 12,395.86

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 35.91

Offering Note

1

Estimated solely for the purposes of calculating the registration fee pursuant to Rule 457(c) under the Securities Act of 1933, as amended, with respect to the additional 200,000 shares of the registrant's voting common stock being newly registered pursuant to this Pre-Effective Amendment, based on the average of the high and low prices of the registrant's voting common stock as quoted on The Nasdaq Capital Market on July 22, 2026 (such date being within five business days of the date that this Pre-Effective Amendment to the Registration Statement was filed with the Securities and Exchange Commission).

2

Reflects the amount of securities, Maximum Aggregate Offering Price, and registration fee previously registered and paid in connection with 40,800,000 shares of the registrant's voting commo stock registered pursuant to the Registration Statement as originally file with the Securities and Exchange Commission on July 16, 2026.

Table 2: Fee Offset Claims and Sources ☑Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rules 457(b) and 0-11(a)(2)
Fee Offset Claims
Fee Offset Sources
Rule 457(p)
Fee Offset Claims
Fee Offset Sources
Table 3: Combined Prospectuses ☑Not Applicable

Security Type

Security Class Title

Amount of Securities Previously Registered

Maximum Aggregate Offering Price of Securities Previously Registered

Form Type

File Number

Initial Effective Date