The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
APPLE INC Common Stock 037833100 79,017,850 273,078 SH SOLE 273,078 0 0
AIRBNB INC-CLASS A Common Stock 009066101 2,730,920 19,084 SH SOLE 19,084 0 0
ANALOG DEVICES INC Common Stock 032654105 14,145,607 35,616 SH SOLE 35,616 0 0
AUTODESK INC Common Stock 052769106 2,012,830 10,353 SH SOLE 10,353 0 0
ASTERA LABS INC Common Stock 04626A103 3,797,020 7,861 SH SOLE 7,861 0 0
APPLIED MATERIALS INC Common Stock 038222105 29,687,103 41,061 SH SOLE 41,061 0 0
ADVANCED MICRO DEVICES Common Stock 007903107 47,907,648 82,470 SH SOLE 82,470 0 0
AMAZON.COM INC Common Stock 023135106 59,567,601 249,927 SH SOLE 249,927 0 0
AMPHENOL CORP-CL A Common Stock 032095101 3,742,754 21,200 SH SOLE 21,200 0 0
APPLOVIN CORP-CLASS A Common Stock 03831W108 8,117,964 15,756 SH SOLE 15,756 0 0
BROADCOM INC Common Stock 11135F101 38,359,010 101,545 SH SOLE 101,545 0 0
CADENCE DESIGN SYS INC Common Stock 127387108 4,693,377 12,505 SH SOLE 12,505 0 0
CIENA CORP Common Stock 171779309 686,784 1,400 SH SOLE 1,400 0 0
CELESTICA INC Common Stock 15101Q207 2,578,406 7,068 SH SOLE 7,068 0 0
COHERENT CORP Common Stock 19247G107 4,548,239 11,530 SH SOLE 11,530 0 0
CREDO TECHNOLOGY GROUP HOLDI Common Stock G25457105 815,850 3,000 SH SOLE 3,000 0 0
SALESFORCE INC Common Stock 79466L302 314,112 2,000 SH SOLE 2,000 0 0
CROWDSTRIKE HOLDINGS INC - A Common Stock 22788C105 7,795,475 10,215 SH SOLE 10,215 0 0
CISCO SYSTEMS INC Common Stock 17275R102 20,839,048 177,414 SH SOLE 177,414 0 0
DOORDASH INC - A Common Stock 25809K105 3,401,811 18,435 SH SOLE 18,435 0 0
DATADOG INC - CLASS A Common Stock 23804L103 4,572,182 17,561 SH SOLE 17,561 0 0
DELL TECHNOLOGIES -C Common Stock 24703L202 776,628 1,800 SH SOLE 1,800 0 0
FORMFACTOR INC Common Stock 346375108 1,487,349 9,300 SH SOLE 9,300 0 0
ALPHABET INC-CL A Common Stock 02079K305 60,388,025 168,979 SH SOLE 168,979 0 0
HEWLETT PACKARD ENTERPRISE Common Stock 42824C109 814,032 18,000 SH SOLE 18,000 0 0
INTEL CORP Common Stock 458140100 37,344,602 267,454 SH SOLE 267,454 0 0
KEYSIGHT TECHNOLOGIES IN Common Stock 49338L103 2,240,448 6,400 SH SOLE 6,400 0 0
KLA CORP Common Stock 482480100 20,563,045 68,155 SH SOLE 68,155 0 0
LUMENTUM HOLDINGS INC Common Stock 55024U109 10,083,921 11,752 SH SOLE 11,752 0 0
LAM RESEARCH CORP Common Stock 512807306 28,460,581 65,644 SH SOLE 65,644 0 0
MASTERCARD INC - A Common Stock 57636Q104 4,375,872 8,520 SH SOLE 8,520 0 0
MICROCHIP TECHNOLOGY INC Common Stock 595017104 3,020,726 33,122 SH SOLE 33,122 0 0
MERCADOLIBRE INC Common Stock 58733R102 3,338,766 1,967 SH SOLE 1,967 0 0
META PLATFORMS INC-CLASS A Common Stock 30303M102 34,302,671 60,897 SH SOLE 60,897 0 0
MONOLITHIC POWER SYSTEMS INC Common Stock 609839105 2,739,240 1,979 SH SOLE 1,979 0 0
MARVELL TECHNOLOGY INC Common Stock 573874104 15,389,295 51,661 SH SOLE 51,661 0 0
MICROSOFT CORP Common Stock 594918104 54,420,634 145,892 SH SOLE 145,892 0 0
MICRON TECHNOLOGY INC Common Stock 595112103 69,117,731 59,879 SH SOLE 59,879 0 0
MAXLINEAR INC Common Stock 57776J100 1,536,360 12,000 SH SOLE 12,000 0 0
CLOUDFLARE INC - CLASS A Common Stock 18915M107 1,103,760 4,500 SH SOLE 4,500 0 0
NETFLIX INC Common Stock 64110L106 15,217,982 213,137 SH SOLE 213,137 0 0
NVIDIA CORP Common Stock 67066G104 101,330,378 506,424 SH SOLE 506,424 0 0
OKTA INC Common Stock 679295105 545,800 4,000 SH SOLE 4,000 0 0
ON SEMICONDUCTOR Common Stock 682189105 1,522,094 16,100 SH SOLE 16,100 0 0
ONTO INNOVATION INC Common Stock 683344105 3,860,190 10,200 SH SOLE 10,200 0 0
PALO ALTO NETWORKS INC Common Stock 697435105 13,954,538 40,920 SH SOLE 40,920 0 0
PALANTIR TECHNOLOGIES INC-A Common Stock 69608A108 11,514,979 98,697 SH SOLE 98,697 0 0
QUALCOMM INC Common Stock 747525103 8,441,762 45,683 SH SOLE 45,683 0 0
RUBRIK INC-A Common Stock 781154109 762,660 9,500 SH SOLE 9,500 0 0
SHOPIFY INC - CLASS A Common Stock 82509L107 4,535,458 39,722 SH SOLE 39,722 0 0
SITIME CORP Common Stock 82982T106 633,726 850 SH SOLE 850 0 0
SANDISK CORP Common Stock 80004C200 22,982,863 10,108 SH SOLE 10,108 0 0
SYNOPSYS INC Common Stock 871607107 4,829,600 10,827 SH SOLE 10,827 0 0
ATLASSIAN CORP-CL A Common Stock 049468101 311,160 4,000 SH SOLE 4,000 0 0
TERADYNE INC Common Stock 880770102 6,381,366 13,189 SH SOLE 13,189 0 0
TOWER SEMICONDUCTOR LTD Common Stock M87915274 2,476,862 9,503 SH SOLE 9,503 0 0
TTM TECHNOLOGIES Common Stock 87305R109 2,805,300 15,000 SH SOLE 15,000 0 0
TWILIO INC - A Common Stock 90138F102 618,990 3,000 SH SOLE 3,000 0 0
UNITY SOFTWARE INC Common Stock 91332U101 1,228,940 43,000 SH SOLE 43,000 0 0
UBER TECHNOLOGIES INC Common Stock 90353T100 2,251,392 31,200 SH SOLE 31,200 0 0
VISA INC-CLASS A SHARES Common Stock 92826C839 6,525,572 19,020 SH SOLE 19,020 0 0
VICOR CORP Common Stock 925815102 569,670 1,500 SH SOLE 1,500 0 0
VERTIV HOLDINGS CO-A Common Stock 92537N108 2,920,970 8,724 SH SOLE 8,724 0 0
WESTERN DIGITAL CORP Common Stock 958102105 15,634,588 24,478 SH SOLE 24,478 0 0
ZETA GLOBAL HOLDINGS CORP-A Common Stock 98956A105 432,960 22,000 SH SOLE 22,000 0 0
ASML HOLDING NV-NY REG SHS NY Reg Shrs N07059210 9,497,587 4,774 SH SOLE 4,774 0 0
ASE TECHNOLOGY HOLDING -ADR ADR 00215W100 4,421,760 98,000 SH SOLE 98,000 0 0
KANZHUN LTD - ADR ADR 48553T106 836,550 65,000 SH SOLE 65,000 0 0
NOKIA CORP-SPON ADR ADR 654902204 2,602,880 196,000 SH SOLE 196,000 0 0
NETEASE INC-ADR ADR 64110W102 2,127,124 16,600 SH SOLE 16,600 0 0
PDD HOLDINGS INC ADR 722304102 2,799,857 36,705 SH SOLE 36,705 0 0
STMICROELECTRONICS NV-NY SHS NY Reg Shrs 861012102 1,872,250 25,000 SH SOLE 25,000 0 0
TAL EDUCATION GROUP- ADR ADR 874080104 669,900 70,000 SH SOLE 70,000 0 0
TRIP.COM GROUP LTD-ADR ADR 89677Q107 398,400 10,000 SH SOLE 10,000 0 0
TAIWAN SEMICONDUCTOR-SP ADR ADR 874039100 16,039,566 33,525 SH SOLE 33,525 0 0
VNET GROUP INC-ADR ADR 90138A103 522,600 65,000 SH SOLE 65,000 0 0
AGILENT TECHNOLOGIES INC Common Stock 00846U101 479,014 3,600 SH SOLE 3,600 0 0
ABSCI CORP Common Stock 00091E109 403,471 34,812 SH SOLE 34,812 0 0
ADIAL PHARMACEUTICALS INC Common Stock 00688A304 20,480 8,000 SH SOLE 8,000 0 0
ALECTOR INC Common Stock 014442107 7,236 3,600 SH SOLE 3,600 0 0
ALX ONCOLOGY HOLDINGS INC Common Stock 00166B105 25,875 12,500 SH SOLE 12,500 0 0
AMGEN INC Common Stock 031162100 26,146,150 72,203 SH SOLE 72,203 0 0
AMN HEALTHCARE SERVICES INC Common Stock 001744101 116,532 3,600 SH SOLE 3,600 0 0
ANNEXON INC Common Stock 03589W102 354,454 62,076 SH SOLE 62,076 0 0
ARTIVA BIOTHERAPEUTICS INC Common Stock 04317A107 15,520 1,600 SH SOLE 1,600 0 0
ATAIBECKLEY INC Common Stock 04650F101 380,352 72,173 SH SOLE 72,173 0 0
ALPHATEC HOLDINGS INC Common Stock 02081G201 216,250 25,000 SH SOLE 25,000 0 0
AURA BIOSCIENCES INC Common Stock 05153U107 174,333 24,554 SH SOLE 24,554 0 0
AXOGEN INC Common Stock 05463X106 221,712 4,800 SH SOLE 4,800 0 0
BIOHAVEN LTD Common Stock G1110E107 148,800 10,000 SH SOLE 10,000 0 0
BROOKDALE SENIOR LIVING INC Common Stock 112463104 201,125 12,500 SH SOLE 12,500 0 0
BRISTOL-MYERS SQUIBB CO Common Stock 110122108 1,555,740 27,000 SH SOLE 27,000 0 0
BOUNDLESS BIO INC Common Stock 10170A100 42,250 16,900 SH SOLE 16,900 0 0
BOSTON SCIENTIFIC CORP Common Stock 101137107 533,500 12,500 SH SOLE 12,500 0 0
BRIGHTSPRING HEALTH SERVICES Common Stock 10950A106 209,220 3,000 SH SOLE 3,000 0 0
CAMP4 THERAPEUTICS CORP Common Stock 13463J101 3,496 800 SH SOLE 800 0 0
CAPRICOR THERAPEUTICS INC Common Stock 14070B309 38,528 1,600 SH SOLE 1,600 0 0
THE CIGNA GROUP Common Stock 125523100 595,469 2,160 SH SOLE 2,160 0 0
HEMAB THERAPEUTICS HOLDINGS Common Stock 423494103 132,228 3,600 SH SOLE 3,600 0 0
CHARLES RIVER LABORATORIES Common Stock 159864107 226,790 1,000 SH SOLE 1,000 0 0
CRINETICS PHARMACEUTICALS IN Common Stock 22663K107 687,817 18,381 SH SOLE 18,381 0 0
CORVUS PHARMACEUTICALS INC Common Stock 221015100 319,462 21,383 SH SOLE 21,383 0 0
CYTOMX THERAPEUTICS INC Common Stock 23284F105 242,426 64,647 SH SOLE 64,647 0 0
CONTINEUM THERAPEUTICS INC-A Common Stock 21217B100 183,699 11,208 SH SOLE 11,208 0 0
CVS HEALTH CORP Common Stock 126650100 1,862,100 18,000 SH SOLE 18,000 0 0
DEFINIUM THERAPEUTICS INC Common Stock 24477V105 1,004,680 21,358 SH SOLE 21,358 0 0
QUEST DIAGNOSTICS INC Common Stock 74834L100 339,120 1,600 SH SOLE 1,600 0 0
DIAMEDICA THERAPEUTICS INC Common Stock 25253X207 17,600 2,500 SH SOLE 2,500 0 0
DENALI THERAPEUTICS INC Common Stock 24823R105 766,945 29,819 SH SOLE 29,819 0 0
BRIGHT MINDS BIOSCIENCES INC Common Stock 10919W405 42,120 600 SH SOLE 600 0 0
DESIGN THERAPEUTICS INC Common Stock 25056L103 1,301,432 89,940 SH SOLE 89,940 0 0
PRECISION BIOSCIENCES INC Common Stock 74019P207 125,760 16,000 SH SOLE 16,000 0 0
DEXCOM INC Common Stock 252131107 950,915 14,119 SH SOLE 14,119 0 0
EDITAS MEDICINE INC Common Stock 28106W103 143,934 44,424 SH SOLE 44,424 0 0
ENCOMPASS HEALTH CORP Common Stock 29261A100 126,350 1,250 SH SOLE 1,250 0 0
ELEDON PHARMACEUTICALS INC Common Stock 28617K101 63,040 16,000 SH SOLE 16,000 0 0
ELEVANCE HEALTH INC Common Stock 036752103 309,384 800 SH SOLE 800 0 0
EUPRAXIA PHARMACEUTICALS INC Common Stock 29842P105 82,625 12,500 SH SOLE 12,500 0 0
EQUILLIUM INC Common Stock 29446K106 80,000 25,000 SH SOLE 25,000 0 0
ERASCA INC Common Stock 29479A108 1,089,912 59,493 SH SOLE 59,493 0 0
ESTABLISHMENT LABS HOLDINGS Common Stock G31249108 68,648 800 SH SOLE 800 0 0
EDGEWISE THERAPEUTICS INC Common Stock 28036F105 746,495 18,373 SH SOLE 18,373 0 0
EYEPOINT INC Common Stock 30233G209 548,305 38,343 SH SOLE 38,343 0 0
FORTE BIOSCIENCES INC Common Stock 34962G208 170,000 8,000 SH SOLE 8,000 0 0
FAETH THERAPEUTICS INC Common Stock 81728A207 90,000 3,600 SH SOLE 3,600 0 0
GH RESEARCH PLC Common Stock G3855L106 360,703 13,419 SH SOLE 13,419 0 0
MONTE ROSA THERAPEUTICS INC Common Stock 61225M102 364,089 15,045 SH SOLE 15,045 0 0
GLOBUS MEDICAL INC - A Common Stock 379577208 158,020 2,000 SH SOLE 2,000 0 0
GRAIL INC Common Stock 384747101 636,959 9,330 SH SOLE 9,330 0 0
CYBIN INC Common Stock 23256X407 39,660 6,000 SH SOLE 6,000 0 0
HUMANA INC Common Stock 444859102 497,521 1,250 SH SOLE 1,250 0 0
IDEXX LABORATORIES INC Common Stock 45168D104 1,439,813 2,735 SH SOLE 2,735 0 0
IDEAYA BIOSCIENCES INC Common Stock 45166A102 568,107 15,243 SH SOLE 15,243 0 0
INFLARX NV Common Stock N44821101 35,840 16,000 SH SOLE 16,000 0 0
IMMUNEERING CORP - CLASS A Common Stock 45254E107 63,857 12,797 SH SOLE 12,797 0 0
IMMUNIC INC Common Stock 4525EP200 98,368 6,400 SH SOLE 6,400 0 0
IMMUNOVANT INC Common Stock 45258J102 1,307,130 33,925 SH SOLE 33,925 0 0
INSPIRE MEDICAL SYSTEMS INC Common Stock 457730109 8,922 200 SH SOLE 200 0 0
IONIS PHARMACEUTICALS INC Common Stock 462222100 6,049,986 76,302 SH SOLE 76,302 0 0
DISC MEDICINE INC Common Stock 254604101 602,600 8,239 SH SOLE 8,239 0 0
IRHYTHM HOLDINGS INC Common Stock 450056106 190,320 1,600 SH SOLE 1,600 0 0
INTUITIVE SURGICAL INC Common Stock 46120E602 5,235,060 13,164 SH SOLE 13,164 0 0
INVIVYD INC Common Stock 00534A102 63,238 72,487 SH SOLE 72,487 0 0
JOHNSON & JOHNSON Common Stock 478160104 7,165,510 28,214 SH SOLE 28,214 0 0
KESTRA MEDICAL TECHNOLOGIES Common Stock G52441105 127,200 5,000 SH SOLE 5,000 0 0
KARYOPHARM THERAPEUTICS INC Common Stock 48576U205 244,250 25,000 SH SOLE 25,000 0 0
ELI LILLY & CO Common Stock 532457108 10,876,431 9,068 SH SOLE 9,068 0 0
VERADERMICS INC Common Stock 922967104 12,294 100 SH SOLE 100 0 0
MAZE THERAPEUTICS INC Common Stock 578784100 412,031 13,808 SH SOLE 13,808 0 0
MBX BIOSCIENCES INC Common Stock 55287L101 506,460 9,175 SH SOLE 9,175 0 0
MCKESSON CORP Common Stock 58155Q103 1,210,141 1,600 SH SOLE 1,600 0 0
MANNKIND CORP Common Stock 56400P706 262,714 61,670 SH SOLE 61,670 0 0
MERCK & CO. INC. Common Stock 58933Y105 3,831,194 29,663 SH SOLE 29,663 0 0
SATELLOS BIOSCIENCE INC Common Stock 80401L803 155,500 20,000 SH SOLE 20,000 0 0
NEWAMSTERDAM PHARMA CO NV Common Stock N62509109 1,647,223 48,605 SH SOLE 48,605 0 0
NEKTAR THERAPEUTICS Common Stock 640268306 111,696 1,600 SH SOLE 1,600 0 0
NATERA INC Common Stock 632307104 977,220 3,600 SH SOLE 3,600 0 0
OMEROS CORP Common Stock 682143102 143,782 15,119 SH SOLE 15,119 0 0
OPTION CARE HEALTH INC Common Stock 68404L201 75,492 3,600 SH SOLE 3,600 0 0
ORIC PHARMACEUTICALS INC Common Stock 68622P109 239,917 22,153 SH SOLE 22,153 0 0
PALISADE BIO INC Common Stock 696389402 141,890 67,890 SH SOLE 67,890 0 0
PARABILIS MEDICINES INC Common Stock 698955101 43,792 1,600 SH SOLE 1,600 0 0
PHARVARIS NV Common Stock N69605108 508,983 14,719 SH SOLE 14,719 0 0
INSULET CORP Common Stock 45784P101 304,500 2,000 SH SOLE 2,000 0 0
PROCEPT BIOROBOTICS CORP Common Stock 74276L105 112,900 5,000 SH SOLE 5,000 0 0
PROQR THERAPEUTICS NV Common Stock N71542109 23,250 12,500 SH SOLE 12,500 0 0
PROTAGONIST THERAPEUTICS INC Common Stock 74366E102 1,407,831 11,485 SH SOLE 11,485 0 0
PELTHOS THERAPEUTICS INC Common Stock 171126204 61,042 2,160 SH SOLE 2,160 0 0
PALVELLA THERAPEUTICS INC Common Stock 697947109 207,377 1,357 SH SOLE 1,357 0 0
RAPPORT THERAPEUTICS INC Common Stock 75383L102 450,536 10,812 SH SOLE 10,812 0 0
AVITA MEDICAL INC Common Stock 05380C102 51,625 12,500 SH SOLE 12,500 0 0
REPLIGEN CORP Common Stock 759916109 341,100 2,500 SH SOLE 2,500 0 0
RESMED INC Common Stock 761152107 194,880 1,000 SH SOLE 1,000 0 0
ROIVANT SCIENCES LTD Common Stock G76279101 4,221,036 119,272 SH SOLE 119,272 0 0
ROYALTY PHARMA PLC- CL A Common Stock G7709Q104 6,759,070 120,547 SH SOLE 120,547 0 0
SEPTERNA INC Common Stock 81734D104 360,821 10,774 SH SOLE 10,774 0 0
SHOULDER INNOVATIONS INC Common Stock 82537J108 101,400 5,000 SH SOLE 5,000 0 0
SUMMIT THERAPEUTICS INC Common Stock 86627T108 1,945,488 133,527 SH SOLE 133,527 0 0
SAREPTA THERAPEUTICS INC Common Stock 803607100 720,633 40,102 SH SOLE 40,102 0 0
SURROZEN INC Common Stock 86889P208 94,718 3,650 SH SOLE 3,650 0 0
STOKE THERAPEUTICS INC Common Stock 86150R107 330,865 10,112 SH SOLE 10,112 0 0
SHATTUCK LABS INC Common Stock 82024L103 101,609 14,641 SH SOLE 14,641 0 0
STRYKER CORP Common Stock 863667101 1,439,282 4,560 SH SOLE 4,560 0 0
TECTONIC THERAPEUTIC INC Common Stock 878972108 189,166 5,503 SH SOLE 5,503 0 0
TENAX THERAPEUTICS INC Common Stock 88032L605 52,380 3,600 SH SOLE 3,600 0 0
TENET HEALTHCARE CORP Common Stock 88033G407 374,160 2,000 SH SOLE 2,000 0 0
TIZIANA LIFE SCIENCES LTD Common Stock G88912103 23,040 18,000 SH SOLE 18,000 0 0
TRANSMEDICS GROUP INC Common Stock 89377M109 6,642 100 SH SOLE 100 0 0
THERMO FISHER SCIENTIFIC INC Common Stock 883556102 2,007,268 4,000 SH SOLE 4,000 0 0
TANDEM DIABETES CARE INC Common Stock 875372203 7,545 500 SH SOLE 500 0 0
TANGO THERAPEUTICS INC Common Stock 87583X109 907,196 29,021 SH SOLE 29,021 0 0
ENTRADA THERAPEUTICS INC Common Stock 29384C108 204,446 27,778 SH SOLE 27,778 0 0
TREVI THERAPEUTICS INC Common Stock 89532M101 432,605 23,196 SH SOLE 23,196 0 0
TAYSHA GENE THERAPIES INC Common Stock 877619106 447,649 65,734 SH SOLE 65,734 0 0
UNITEDHEALTH GROUP INC Common Stock 91324P102 3,469,264 8,347 SH SOLE 8,347 0 0
VENTURE GLOBAL INC-CL A Common Stock 92333F101 278,250 25,000 SH SOLE 25,000 0 0
VERTEX PHARMACEUTICALS INC Common Stock 92532F100 23,974,673 48,265 SH SOLE 48,265 0 0
VTV THERAPEUTICS INC- CL A Common Stock 918385204 94,125 2,500 SH SOLE 2,500 0 0
XERIS BIOPHARMA HOLDINGS INC Common Stock 98422E103 246,122 31,076 SH SOLE 31,076 0 0
DENTSPLY SIRONA INC Common Stock 24906P109 67,904 6,400 SH SOLE 6,400 0 0
ZENAS BIOPHARMA INC Common Stock 98937L105 478,362 18,848 SH SOLE 18,848 0 0
ZURA BIO LTD Common Stock G9TY5A101 94,400 16,000 SH SOLE 16,000 0 0
ARGENX SE - ADR ADR 04016X101 4,306,708 4,642 SH SOLE 4,642 0 0
DBV TECHNOLOGIES SA-SPON ADR ADR 23306J309 131,200 8,000 SH SOLE 8,000 0 0
IMMUNOCORE HOLDINGS PLC-ADR ADR 45258D105 231,045 7,277 SH SOLE 7,277 0 0
INVENTIVA SA - ADR ADR 46124U107 81,648 21,600 SH SOLE 21,600 0 0
NOVARTIS AG-SPONSORED ADR ADR 66987V109 7,679,280 49,000 SH SOLE 49,000 0 0
SS SPDR S&P BIOTECH ETF ETP 78464A870 96,216 608 SH SOLE 608 0 0
GSK PLC-SPON ADR ADR 37733W204 9,071 0 SH SOLE 0 0 0
PETROLEO BRASILEIRO-SPON ADR ADR 71654V408 2,434 0 SH SOLE 0 0 0
CHIPOTLE MEXICAN GRILL INC Common Stock 169656105 2,074 61 SH SOLE 61 0 0
COSTCO WHOLESALE CORP Common Stock 22160K105 16,703,752 17,856 SH SOLE 17,856 0 0
DECKERS OUTDOOR CORP Common Stock 243537107 416,323 4,193 SH SOLE 4,193 0 0
GE VERNOVA INC Common Stock 36828A101 2,251,846 1,916 SH SOLE 1,916 0 0
ALPHABET INC-CL C Common Stock 02079K107 29,098,845 82,356 SH SOLE 82,356 0 0
HOME DEPOT INC Common Stock 437076102 4,559,447 12,928 SH SOLE 12,928 0 0
HILTON WORLDWIDE HOLDINGS IN Common Stock 43300A203 337,400 1,021 SH SOLE 1,021 0 0
HERSHEY CO/THE Common Stock 427866108 1,755 10 SH SOLE 10 0 0
COCA-COLA CO/THE Common Stock 191216100 3,100,812 38,023 SH SOLE 38,023 0 0
MCDONALD'S CORP Common Stock 580135101 2,865,827 10,602 SH SOLE 10,602 0 0
PROCTER & GAMBLE CO/THE Common Stock 742718109 2,138,744 14,585 SH SOLE 14,585 0 0
FERRARI NV Common Stock N3167Y103 2,330,535 6,260 SH SOLE 6,260 0 0
ROYAL CARIBBEAN CRUISES LTD Common Stock V7780T103 40,009 126 SH SOLE 126 0 0
STARBUCKS CORP Common Stock 855244109 3,516,664 34,413 SH SOLE 34,413 0 0
TJX COMPANIES INC Common Stock 872540109 636,300 4,200 SH SOLE 4,200 0 0
WALMART INC Common Stock 931142103 21,486,102 189,706 SH SOLE 189,706 0 0
ATOUR LIFESTYLE HOLDINGS-ADR ADR 04965M106 564,450 17,750 SH SOLE 17,750 0 0
ALIBABA GROUP HOLDING-SP ADR ADR 01609W102 334,199 3,445 SH SOLE 3,445 0 0
BRITISH AMERICAN TOB-SP ADR ADR 110448107 2,281,847 36,947 SH SOLE 36,947 0 0
DIAGEO PLC-SPONSORED ADR ADR 25243Q205 151,436 1,884 SH SOLE 1,884 0 0
TENCENT MUSIC ENTERTAINM-ADR ADR 88034P109 4,175 500 SH SOLE 500 0 0
SS CONSUMER DISC SELECT SECT ETP 81369Y407 707,198 6,030 SH SOLE 6,030 0 0
CHINA YUCHAI INTL LTD Common Stock G21082105 260,755 5,500 SH SOLE 5,500 0 0
TESLA INC Common Stock 88160R101 28,299,230 67,283 SH SOLE 67,283 0 0
TEXAS INSTRUMENTS INC Common Stock 882508104 9,675,650 32,461 SH SOLE 32,461 0 0
NIO INC - ADR ADR 62914V106 379,500 75,000 SH SOLE 75,000 0 0
UXIN LTD - ADR ADR 91818X306 54,250 35,000 SH SOLE 35,000 0 0
WERIDE INC-ADR ADR 950915108 174,600 30,000 SH SOLE 30,000 0 0
ABBVIE INC Common Stock 00287Y109 1,739,587 6,913 SH SOLE 6,913 0 0
BANK OF AMERICA CORP Common Stock 060505104 1,511,736 26,531 SH SOLE 26,531 0 0
BERKSHIRE HATHAWAY INC-CL B Common Stock 084670702 2,719,620 5,435 SH SOLE 5,435 0 0
CATERPILLAR INC Common Stock 149123101 1,935,988 1,818 SH SOLE 1,818 0 0
CHEVRON CORP Common Stock 166764100 1,195,793 7,214 SH SOLE 7,214 0 0
GENERAL ELECTRIC Common Stock 369604301 1,526,313 4,084 SH SOLE 4,084 0 0
GOLDMAN SACHS GROUP INC Common Stock 38141G104 1,166,110 1,153 SH SOLE 1,153 0 0
INTL BUSINESS MACHINES CORP Common Stock 459200101 1,030,916 3,666 SH SOLE 3,666 0 0
JPMORGAN CHASE & CO Common Stock 46625H100 3,431,400 10,483 SH SOLE 10,483 0 0
LINDE PLC Common Stock G54950103 8,163,964 15,732 SH SOLE 15,732 0 0
MORGAN STANLEY Common Stock 617446448 968,064 4,631 SH SOLE 4,631 0 0
ORACLE CORP Common Stock 68389X105 988,333 6,744 SH SOLE 6,744 0 0
PEPSICO INC Common Stock 713448108 6,295,558 46,496 SH SOLE 46,496 0 0
PHILIP MORRIS INTERNATIONAL Common Stock 718172109 1,109,513 6,091 SH SOLE 6,091 0 0
RTX CORP Common Stock 75513E101 997,980 5,260 SH SOLE 5,260 0 0
VERIZON COMMUNICATIONS INC Common Stock 92343V104 691,709 16,337 SH SOLE 16,337 0 0
WELLS FARGO & CO Common Stock 949746101 989,697 11,976 SH SOLE 11,976 0 0
EXXONMOBIL HOLDINGS CORP Common Stock 30231G102 2,221,016 16,245 SH SOLE 16,245 0 0
ADOBE INC Common Stock 00724F101 2,495,298 12,171 SH SOLE 12,171 0 0
AUTOMATIC DATA PROCESSING Common Stock 053015103 2,713,662 12,036 SH SOLE 12,036 0 0
AMERICAN ELECTRIC POWER Common Stock 025537101 2,241,358 16,383 SH SOLE 16,383 0 0
ALNYLAM PHARMACEUTICALS INC Common Stock 02043Q107 7,606,727 25,269 SH SOLE 25,269 0 0
AXON ENTERPRISE INC Common Stock 05464C101 1,360,600 2,427 SH SOLE 2,427 0 0
BOOKING HOLDINGS INC Common Stock 09857L108 4,158,696 23,332 SH SOLE 23,332 0 0
BAKER HUGHES CO Common Stock 05722G100 1,657,841 29,871 SH SOLE 29,871 0 0
COCA-COLA EUROPACIFIC PARTNE Common Stock G25839104 1,343,540 13,426 SH SOLE 13,426 0 0
CONSTELLATION ENERGY Common Stock 21037T109 2,701,272 10,876 SH SOLE 10,876 0 0
COMCAST CORP-CLASS A Common Stock 20030N101 2,633,626 107,276 SH SOLE 107,276 0 0
COPART INC Common Stock 217204106 785,824 27,876 SH SOLE 27,876 0 0
COREWEAVE INC-CL A Common Stock 21873S108 1,341,501 13,477 SH SOLE 13,477 0 0
CSX CORP Common Stock 126408103 2,659,256 55,949 SH SOLE 55,949 0 0
CINTAS CORP Common Stock 172908105 2,048,954 12,047 SH SOLE 12,047 0 0
ELECTRONIC ARTS INC Common Stock 285512109 1,548,052 7,550 SH SOLE 7,550 0 0
EXELON CORP Common Stock 30161N101 1,436,316 30,809 SH SOLE 30,809 0 0
DIAMONDBACK ENERGY INC Common Stock 25278X109 1,488,857 8,470 SH SOLE 8,470 0 0
FASTENAL CO Common Stock 311900104 1,660,301 34,568 SH SOLE 34,568 0 0
FERROVIAL NV Common Stock N3168P101 1,486,298 21,663 SH SOLE 21,663 0 0
FORTINET INC Common Stock 34959E109 3,388,857 22,060 SH SOLE 22,060 0 0
GE HEALTHCARE TECHNOLOGY Common Stock 36266G107 876,745 13,697 SH SOLE 13,697 0 0
GILEAD SCIENCES INC Common Stock 375558103 20,407,448 161,528 SH SOLE 161,528 0 0
HONEYWELL INTERNATIONAL INC Common Stock 438516205 2,136,006 9,540 SH SOLE 9,540 0 0
HONEYWELL AEROSPACE INC Common Stock 43849R105 2,109,103 9,540 SH SOLE 9,540 0 0
INTUIT INC Common Stock 461202103 2,149,596 8,236 SH SOLE 8,236 0 0
KEURIG DR PEPPER INC Common Stock 49271V100 1,349,219 40,967 SH SOLE 40,967 0 0
KRAFT HEINZ CO/THE Common Stock 500754106 843,328 35,704 SH SOLE 35,704 0 0
MARRIOTT INTERNATIONAL -CL A Common Stock 571903202 2,942,485 7,940 SH SOLE 7,940 0 0
MONDELEZ INTERNATIONAL INC-A Common Stock 609207105 2,252,879 38,651 SH SOLE 38,651 0 0
MONSTER BEVERAGE CORP Common Stock 61174X109 2,830,542 29,448 SH SOLE 29,448 0 0
STRATEGY INC Common Stock 594972408 865,910 9,961 SH SOLE 9,961 0 0
NEBIUS GROUP NV Common Stock N97284108 1,832,664 6,636 SH SOLE 6,636 0 0
NXP SEMICONDUCTORS NV Common Stock N6596X109 2,142,800 7,602 SH SOLE 7,602 0 0
OLD DOMINION FREIGHT LINE Common Stock 679580100 1,356,349 6,262 SH SOLE 6,262 0 0
O'REILLY AUTOMOTIVE INC Common Stock 67103H107 2,297,922 24,953 SH SOLE 24,953 0 0
PAYCHEX INC Common Stock 704326107 1,060,784 10,788 SH SOLE 10,788 0 0
PACCAR INC Common Stock 693718108 1,903,542 15,847 SH SOLE 15,847 0 0
PAYPAL HOLDINGS INC Common Stock 70450Y103 1,146,861 26,560 SH SOLE 26,560 0 0
REGENERON PHARMACEUTICALS Common Stock 75886F107 12,157,783 19,498 SH SOLE 19,498 0 0
ROCKET LAB CORP Common Stock 773121108 1,771,353 17,426 SH SOLE 17,426 0 0
ROPER TECHNOLOGIES INC Common Stock 776696106 1,028,367 3,039 SH SOLE 3,039 0 0
ROSS STORES INC Common Stock 778296103 2,064,645 9,700 SH SOLE 9,700 0 0
SEAGATE TECHNOLOGY HOLDINGS Common Stock G7997R103 6,519,346 6,752 SH SOLE 6,752 0 0
T-MOBILE US INC Common Stock 872590104 5,465,482 32,585 SH SOLE 32,585 0 0
THOMSON REUTERS CORP Common Stock 884903881 937,082 11,474 SH SOLE 11,474 0 0
TAKE-TWO INTERACTIVE SOFTWRE Common Stock 874054109 1,397,388 5,590 SH SOLE 5,590 0 0
WARNER BROS DISCOVERY INC Common Stock 934423104 2,012,563 75,490 SH SOLE 75,490 0 0
WORKDAY INC-CLASS A Common Stock 98138H101 740,886 6,052 SH SOLE 6,052 0 0
XCEL ENERGY INC Common Stock 98389B100 1,519,227 18,797 SH SOLE 18,797 0 0
ARM HOLDINGS PLC-ADR ADR 042068205 4,851,581 13,683 SH SOLE 13,683 0 0
GOLDMAN SACHS PHYSICAL GOLD ETP 38150K103 9,575,940 242,000 SH SOLE 242,000 0 0
GRANITESHARES GOLD TRUST ETP 38748G101 11,977,590 303,000 SH SOLE 303,000 0 0
SPDR GOLD SHARES ETP 78463V107 21,881,772 59,400 SH SOLE 59,400 0 0
SPDR GOLD MINISHARES TRUST ETP 98149E303 21,657,834 272,700 SH SOLE 272,700 0 0
ISHARES GOLD TRUST ETP 464285204 22,497,449 297,940 SH SOLE 297,940 0 0
ISHARES GOLD TRUST MICRO ETP 46436F103 14,123,530 353,000 SH SOLE 353,000 0 0
ABRDN PHYSICAL GOLD SHARES ETP 00326A104 10,570,595 276,500 SH SOLE 276,500 0 0
PROSHARES ULTRA GOLD ETP 74347W601 7,295,581 166,300 SH SOLE 166,300 0 0
PGIM ULTRA SHORT BOND ETF ETP 69344A107 496,984 10,000 SH SOLE 10,000 0 0
VANGUARD ULTRA SHORT BOND ET ETP 92203C303 278,768 5,600 SH SOLE 5,600 0 0
AARDVARK THERAPEUTICS INC Common Stock 002942100 19,999 3,472 SH SOLE 3,472 0 0
ABCELLERA BIOLOGICS INC Common Stock 00288U106 381,518 48,601 SH SOLE 48,601 0 0
ARBUTUS BIOPHARMA CORP Common Stock 03879J100 150,902 31,438 SH SOLE 31,438 0 0
ACADIA PHARMACEUTICALS INC Common Stock 004225108 689,476 27,252 SH SOLE 27,252 0 0
AC IMMUNE SA Common Stock H00263105 38,549 16,197 SH SOLE 16,197 0 0
ACLARIS THERAPEUTICS INC Common Stock 00461U105 117,586 22,228 SH SOLE 22,228 0 0
ADMA BIOLOGICS INC Common Stock 000899104 308,744 36,887 SH SOLE 36,887 0 0
ADAPTIVE BIOTECHNOLOGIES Common Stock 00650F109 546,353 25,471 SH SOLE 25,471 0 0
AGIOS PHARMACEUTICALS INC Common Stock 00847X104 351,246 9,465 SH SOLE 9,465 0 0
ALKERMES PLC Common Stock G01767105 1,389,882 26,527 SH SOLE 26,527 0 0
ALLOGENE THERAPEUTICS INC Common Stock 019770106 114,256 54,931 SH SOLE 54,931 0 0
ALUMIS INC Common Stock 022307102 552,782 19,644 SH SOLE 19,644 0 0
ALTIMMUNE INC Common Stock 02155H200 94,091 30,951 SH SOLE 30,951 0 0
ALVOTECH SA Common Stock L01800108 183,256 49,663 SH SOLE 49,663 0 0
AMYLYX PHARMACEUTICALS INC Common Stock 03237H101 317,802 17,695 SH SOLE 17,695 0 0
AMPHASTAR PHARMACEUTICALS IN Common Stock 03209R103 141,603 7,017 SH SOLE 7,017 0 0
AMNEAL PHARMACEUTICALS INC Common Stock 03168L105 878,881 50,773 SH SOLE 50,773 0 0
ANAPTYSBIO INC Common Stock 032724106 312,593 4,631 SH SOLE 4,631 0 0
ANI PHARMACEUTICALS INC Common Stock 00182C103 299,498 3,618 SH SOLE 3,618 0 0
APOGEE THERAPEUTICS INC Common Stock 03770N101 1,307,656 9,852 SH SOLE 9,852 0 0
AQUESTIVE THERAPEUTICS INC Common Stock 03843E104 83,054 19,965 SH SOLE 19,965 0 0
ARCTURUS THERAPEUTICS HOLDIN Common Stock 03969T109 30,401 4,524 SH SOLE 4,524 0 0
ARDELYX INC Common Stock 039697107 200,507 39,315 SH SOLE 39,315 0 0
ARCUTIS BIOTHERAPEUTICS INC Common Stock 03969K108 521,962 19,907 SH SOLE 19,907 0 0
ARVINAS INC Common Stock 04335A105 85,335 10,269 SH SOLE 10,269 0 0
ARROWHEAD PHARMACEUTICALS IN Common Stock 04280A100 1,827,210 22,417 SH SOLE 22,417 0 0
ASCENDIS PHARMA A/S Common Stock K08588103 2,613,323 9,798 SH SOLE 9,798 0 0
AURINIA PHARMACEUTICALS INC Common Stock 05156V102 347,325 20,467 SH SOLE 20,467 0 0
ARRIVENT BIOPHARMA INC Common Stock 04272N102 257,493 7,412 SH SOLE 7,412 0 0
ATEA PHARMACEUTICALS INC Common Stock 04683R106 59,222 12,736 SH SOLE 12,736 0 0
ANAVEX LIFE SCIENCES CORP Common Stock 032797300 38,200 14,749 SH SOLE 14,749 0 0
AXSOME THERAPEUTICS INC Common Stock 05464T104 2,004,666 8,190 SH SOLE 8,190 0 0
BRIDGEBIO PHARMA INC Common Stock 10806X102 2,321,616 31,171 SH SOLE 31,171 0 0
BICARA THERAPEUTICS INC Common Stock 055477103 310,468 10,457 SH SOLE 10,457 0 0
BIOCRYST PHARMACEUTICALS INC Common Stock 09058V103 404,500 40,450 SH SOLE 40,450 0 0
BLACK DIAMOND THERAPEUTICS I Common Stock 09203E105 16,872 9,120 SH SOLE 9,120 0 0
BEAM THERAPEUTICS INC Common Stock 07373V105 561,921 16,373 SH SOLE 16,373 0 0
BIOGEN INC Common Stock 09062X103 5,076,762 23,497 SH SOLE 23,497 0 0
BIOAGE LABS INC Common Stock 09077V100 173,408 7,075 SH SOLE 7,075 0 0
BIOMARIN PHARMACEUTICAL INC Common Stock 09061G101 1,760,144 30,761 SH SOLE 30,761 0 0
CABALETTA BIO INC Common Stock 12674W109 80,705 25,950 SH SOLE 25,950 0 0
CANDEL THERAPEUTICS INC Common Stock 137404109 120,108 11,661 SH SOLE 11,661 0 0
CARIS LIFE SCIENCES INC Common Stock 142152107 801,704 44,989 SH SOLE 44,989 0 0
C4 THERAPEUTICS INC Common Stock 12529R107 82,178 17,597 SH SOLE 17,597 0 0
CODEXIS INC Common Stock 192005106 32,693 14,466 SH SOLE 14,466 0 0
CULLINAN THERAPEUTICS INC Common Stock 230031106 178,112 9,781 SH SOLE 9,781 0 0
CG ONCOLOGY INC Common Stock 156944100 997,329 14,037 SH SOLE 14,037 0 0
COHERUS ONCOLOGY INC Common Stock 19249H103 34,369 24,549 SH SOLE 24,549 0 0
COGENT BIOSCIENCES INC Common Stock 19240Q201 1,052,408 27,194 SH SOLE 27,194 0 0
COLLEGIUM PHARMACEUTICAL INC Common Stock 19459J104 186,864 5,162 SH SOLE 5,162 0 0
CARIBOU BIOSCIENCES INC Common Stock 142038108 27,782 15,785 SH SOLE 15,785 0 0
CORMEDIX INC Common Stock 21900C308 98,015 12,486 SH SOLE 12,486 0 0
CRISPR THERAPEUTICS AG Common Stock H17182108 837,189 15,350 SH SOLE 15,350 0 0
CASTLE BIOSCIENCES INC Common Stock 14843C105 115,124 4,827 SH SOLE 4,827 0 0
CYTOKINETICS INC Common Stock 23282W605 1,838,145 21,577 SH SOLE 21,577 0 0
DYNE THERAPEUTICS INC Common Stock 26818M108 584,345 26,310 SH SOLE 26,310 0 0
ENLIVEN THERAPEUTICS INC Common Stock 29337E102 491,920 9,693 SH SOLE 9,693 0 0
ENANTA PHARMACEUTICALS INC Common Stock 29251M106 67,476 4,628 SH SOLE 4,628 0 0
EVOLUS INC Common Stock 30052C107 72,738 10,481 SH SOLE 10,481 0 0
ESPERION THERAPEUTICS INC Common Stock 29664W105 129,465 40,970 SH SOLE 40,970 0 0
ETON PHARMACEUTICALS INC Common Stock 29772L108 157,832 4,360 SH SOLE 4,360 0 0
EXELIXIS INC Common Stock 30161Q104 2,176,563 40,003 SH SOLE 40,003 0 0
4D MOLECULAR THERAPEUTICS IN Common Stock 35104E100 110,656 8,320 SH SOLE 8,320 0 0
FOGHORN THERAPEUTICS INC Common Stock 344174107 45,599 9,344 SH SOLE 9,344 0 0
FORTREA HOLDINGS INC Common Stock 34965K107 261,974 15,056 SH SOLE 15,056 0 0
FULCRUM THERAPEUTICS INC Common Stock 359616109 38,814 10,605 SH SOLE 10,605 0 0
GERON CORP Common Stock 374163103 130,685 102,098 SH SOLE 102,098 0 0
GUARDANT HEALTH INC Common Stock 40131M109 3,166,083 21,103 SH SOLE 21,103 0 0
GOSSAMER BIO INC Common Stock 38341P102 6,148 37,352 SH SOLE 37,352 0 0
HALOZYME THERAPEUTICS INC Common Stock 40637H109 1,477,503 18,877 SH SOLE 18,877 0 0
HARMONY BIOSCIENCES HOLDINGS Common Stock 413197104 335,482 9,214 SH SOLE 9,214 0 0
HARROW INC Common Stock 415858109 251,932 5,932 SH SOLE 5,932 0 0
HUMACYTE INC Common Stock 44486Q103 27,575 35,334 SH SOLE 35,334 0 0
IMMUNITYBIO INC Common Stock 45256X103 1,459,345 166,687 SH SOLE 166,687 0 0
INHIBRX BIOSCIENCES INC Common Stock 45720N103 221,241 2,335 SH SOLE 2,335 0 0
INCYTE CORP Common Stock 45337C102 3,604,281 31,795 SH SOLE 31,795 0 0
INDIVIOR PHARMACEUTICALS INC Common Stock 45579U109 796,146 19,404 SH SOLE 19,404 0 0
INSMED INC Common Stock 457669307 3,677,964 34,496 SH SOLE 34,496 0 0
INNOVIVA INC Common Stock 45781M101 266,774 11,747 SH SOLE 11,747 0 0
IOVANCE BIOTHERAPEUTICS INC Common Stock 462260100 295,614 71,061 SH SOLE 71,061 0 0
IRONWOOD PHARMACEUTICALS INC Common Stock 46333X108 110,294 26,198 SH SOLE 26,198 0 0
JANUX THERAPEUTICS INC Common Stock 47103J105 149,084 9,706 SH SOLE 9,706 0 0
JAZZ PHARMACEUTICALS PLC Common Stock G50871105 2,406,326 9,986 SH SOLE 9,986 0 0
KAMADA LTD Common Stock M6240T109 67,389 9,181 SH SOLE 9,181 0 0
KINIKSA PHARMACEUTICALS INTE Common Stock G52694109 471,248 7,369 SH SOLE 7,369 0 0
KODIAK SCIENCES INC Common Stock 50015M109 388,003 9,959 SH SOLE 9,959 0 0
KEROS THERAPEUTICS INC Common Stock 492327101 33,705 3,150 SH SOLE 3,150 0 0
KRYSTAL BIOTECH INC Common Stock 501147102 1,743,876 4,692 SH SOLE 4,692 0 0
KURA ONCOLOGY INC Common Stock 50127T109 154,984 14,128 SH SOLE 14,128 0 0
KYMERA THERAPEUTICS INC Common Stock 501575104 1,501,145 13,091 SH SOLE 13,091 0 0
KYVERNA THERAPEUTICS INC Common Stock 501976104 86,213 9,676 SH SOLE 9,676 0 0
LENZ THERAPEUTICS INC Common Stock 52635N103 28,343 4,990 SH SOLE 4,990 0 0
LIFECORE BIOMEDICAL INC Common Stock 514766104 31,343 5,970 SH SOLE 5,970 0 0
LIGAND PHARMACEUTICALS Common Stock 53220K504 1,008,327 3,190 SH SOLE 3,190 0 0
LARIMAR THERAPEUTICS INC Common Stock 517125100 50,426 16,533 SH SOLE 16,533 0 0
LEXEO THERAPEUTICS INC Common Stock 52886X107 58,174 12,497 SH SOLE 12,497 0 0
LYELL IMMUNOPHARMA INC Common Stock 55083R203 52,182 3,714 SH SOLE 3,714 0 0
MADRIGAL PHARMACEUTICALS INC Common Stock 558868105 1,970,070 3,669 SH SOLE 3,669 0 0
MEDPACE HOLDINGS INC Common Stock 58506Q109 2,406,987 4,545 SH SOLE 4,545 0 0
JYONG BIOTECH LTD Common Stock G83116106 25,047 12,100 SH SOLE 12,100 0 0
MEIRAGTX HOLDINGS PLC Common Stock G59665102 199,124 14,739 SH SOLE 14,739 0 0
MIRUM PHARMACEUTICALS INC Common Stock 604749101 1,136,164 9,705 SH SOLE 9,705 0 0
MINERALYS THERAPEUTICS INC Common Stock 603170101 354,247 13,130 SH SOLE 13,130 0 0
MODERNA INC Common Stock 60770K107 4,422,324 63,149 SH SOLE 63,149 0 0
MARAVAI LIFESCIENCES HLDGS-A Common Stock 56600D107 146,490 23,476 SH SOLE 23,476 0 0
NEUROCRINE BIOSCIENCES INC Common Stock 64125C109 2,697,066 16,003 SH SOLE 16,003 0 0
NEUROGENE INC Common Stock 64135M105 79,097 2,515 SH SOLE 2,515 0 0
NEUMORA THERAPEUTICS INC Common Stock 640979100 50,130 29,488 SH SOLE 29,488 0 0
NURIX THERAPEUTICS INC Common Stock 67080M103 399,247 16,457 SH SOLE 16,457 0 0
INTELLIA THERAPEUTICS INC Common Stock 45826J105 376,250 22,237 SH SOLE 22,237 0 0
NUVALENT INC-A Common Stock 670703107 1,445,938 11,708 SH SOLE 11,708 0 0
NOVAVAX INC Common Stock 670002401 246,521 26,170 SH SOLE 26,170 0 0
NOVOCURE LTD Common Stock G6674U108 279,260 18,433 SH SOLE 18,433 0 0
OMNIAB INC Common Stock 68218J103 56,757 23,072 SH SOLE 23,072 0 0
ORCHESTRA BIOMED HOLDINGS IN Common Stock 68572M106 41,122 9,530 SH SOLE 9,530 0 0
OCULAR THERAPEUTIX INC Common Stock 67576A100 342,207 34,848 SH SOLE 34,848 0 0
OLEMA PHARMACEUTICALS INC Common Stock 68062P106 173,902 13,901 SH SOLE 13,901 0 0
ORUKA THERAPEUTICS INC Common Stock 687604108 913,537 9,599 SH SOLE 9,599 0 0
PACIFIC BIOSCIENCES OF CALIF Common Stock 69404D108 83,046 49,432 SH SOLE 49,432 0 0
PHIBRO ANIMAL HEALTH CORP-A Common Stock 71742Q106 105,284 3,353 SH SOLE 3,353 0 0
PUMA BIOTECHNOLOGY INC Common Stock 74587V107 65,699 8,101 SH SOLE 8,101 0 0
PACIRA BIOSCIENCES INC Common Stock 695127100 158,867 6,262 SH SOLE 6,262 0 0
VAXCYTE INC Common Stock 92243G108 1,335,886 22,981 SH SOLE 22,981 0 0
PEPGEN INC Common Stock 713317105 19,814 11,008 SH SOLE 11,008 0 0
PRECIGEN INC Common Stock 74017N105 323,412 56,739 SH SOLE 56,739 0 0
PHATHOM PHARMACEUTICALS INC Common Stock 71722W107 137,719 12,693 SH SOLE 12,693 0 0
PRAXIS PRECISION MEDICINES I Common Stock 74006W207 1,485,463 4,437 SH SOLE 4,437 0 0
PRIME MEDICINE INC Common Stock 74168J101 106,069 28,745 SH SOLE 28,745 0 0
PROTHENA CORP PLC Common Stock G72800108 81,570 8,332 SH SOLE 8,332 0 0
PERSONALIS INC Common Stock 71535D106 223,324 16,666 SH SOLE 16,666 0 0
PTC THERAPEUTICS INC Common Stock 69366J200 1,076,806 13,201 SH SOLE 13,201 0 0
PYXIS ONCOLOGY INC Common Stock 747324101 30,350 10,083 SH SOLE 10,083 0 0
QUANTUM-SI INC Common Stock 74765K105 27,863 31,484 SH SOLE 31,484 0 0
UNIQURE NV Common Stock N90064101 462,304 10,037 SH SOLE 10,037 0 0
RANI THERAPEUTICS HOLDINGS-A Common Stock 753018100 13,601 17,887 SH SOLE 17,887 0 0
ULTRAGENYX PHARMACEUTICAL IN Common Stock 90400D108 523,388 15,675 SH SOLE 15,675 0 0
ROCKET PHARMACEUTICALS INC Common Stock 77313F106 59,433 17,378 SH SOLE 17,378 0 0
REPLIMUNE GROUP INC Common Stock 76029N106 145,471 13,141 SH SOLE 13,141 0 0
REGENXBIO INC Common Stock 75901B107 98,571 8,228 SH SOLE 8,228 0 0
RIGEL PHARMACEUTICALS INC Common Stock 766559702 115,208 2,945 SH SOLE 2,945 0 0
RELAY THERAPEUTICS INC Common Stock 75943R102 638,722 34,138 SH SOLE 34,138 0 0
REVOLUTION MEDICINES INC Common Stock 76155X100 6,336,619 33,835 SH SOLE 33,835 0 0
RECURSION PHARMACEUTICALS-A Common Stock 75629V104 306,456 83,503 SH SOLE 83,503 0 0
RHYTHM PHARMACEUTICALS INC Common Stock 76243J105 1,212,115 10,917 SH SOLE 10,917 0 0
SANA BIOTECHNOLOGY INC Common Stock 799566104 154,572 44,290 SH SOLE 44,290 0 0
SAGIMET BIOSCIENCES INC-A Common Stock 786700104 75,275 9,738 SH SOLE 9,738 0 0
SIGA TECHNOLOGIES INC Common Stock 826917106 41,551 11,415 SH SOLE 11,415 0 0
SIONNA THERAPEUTICS INC Common Stock 829401108 316,112 7,186 SH SOLE 7,186 0 0
SOLID BIOSCIENCES INC Common Stock 83422E204 156,523 15,668 SH SOLE 15,668 0 0
SYNDAX PHARMACEUTICALS INC Common Stock 87164F105 308,270 14,102 SH SOLE 14,102 0 0
ARS PHARMACEUTICALS INC Common Stock 82835W108 126,590 15,804 SH SOLE 15,804 0 0
SCHOLAR ROCK HOLDING CORP Common Stock 80706P103 1,048,905 19,071 SH SOLE 19,071 0 0
SUPERNUS PHARMACEUTICALS INC Common Stock 868459108 429,613 9,237 SH SOLE 9,237 0 0
SAVARA INC Common Stock 805111101 200,902 32,614 SH SOLE 32,614 0 0
SPYRE THERAPEUTICS INC Common Stock 00773J202 1,227,028 13,821 SH SOLE 13,821 0 0
TARSUS PHARMACEUTICALS INC Common Stock 87650L103 430,950 6,847 SH SOLE 6,847 0 0
THERAVANCE BIOPHARMA INC Common Stock G8807B106 139,485 8,205 SH SOLE 8,205 0 0
TEMPUS AI INC-CL A Common Stock 88023B103 1,609,006 27,775 SH SOLE 27,775 0 0
ALPHA TEKNOVA INC Common Stock 02080L102 48,467 8,533 SH SOLE 8,533 0 0
TENAYA THERAPEUTICS INC Common Stock 87990A106 25,525 34,535 SH SOLE 34,535 0 0
FIRST TRACKS BIOTHERAPEUTICS Common Stock 337185102 111,726 5,553 SH SOLE 5,553 0 0
TRAVERE THERAPEUTICS INC Common Stock 89422G107 840,788 14,800 SH SOLE 14,800 0 0
TWIST BIOSCIENCE CORP Common Stock 90184D100 1,019,644 9,911 SH SOLE 9,911 0 0
10X GENOMICS INC-CLASS A Common Stock 88025U109 713,162 18,601 SH SOLE 18,601 0 0
TYRA BIOSCIENCES INC Common Stock 90240B106 302,312 9,465 SH SOLE 9,465 0 0
UPSTREAM BIO INC Common Stock 91678A107 59,934 8,661 SH SOLE 8,661 0 0
UROGEN PHARMA LTD Common Stock M96088105 285,347 7,754 SH SOLE 7,754 0 0
UNITED THERAPEUTICS CORP Common Stock 91307C102 3,660,062 6,755 SH SOLE 6,755 0 0
VERICEL CORP Common Stock 92346J108 361,615 8,128 SH SOLE 8,128 0 0
VERACYTE INC Common Stock 92337F107 745,812 12,699 SH SOLE 12,699 0 0
VERA THERAPEUTICS INC Common Stock 92337R101 490,204 11,424 SH SOLE 11,424 0 0
VIR BIOTECHNOLOGY INC Common Stock 92764N102 273,510 26,841 SH SOLE 26,841 0 0
VANDA PHARMACEUTICALS INC Common Stock 921659108 58,575 9,571 SH SOLE 9,571 0 0
VOR BIOPHARMA INC Common Stock 929033207 158,768 8,624 SH SOLE 8,624 0 0
VIATRIS INC Common Stock 92556V106 2,943,183 185,339 SH SOLE 185,339 0 0
VOYAGER THERAPEUTICS INC Common Stock 92915B106 33,656 9,616 SH SOLE 9,616 0 0
WAVE LIFE SCIENCES LTD Common Stock Y95308105 177,908 30,621 SH SOLE 30,621 0 0
XENON PHARMACEUTICALS INC Common Stock 98420N105 928,578 15,384 SH SOLE 15,384 0 0
XENCOR INC Common Stock 98401F105 189,980 11,800 SH SOLE 11,800 0 0
ZEVRA THERAPEUTICS INC Common Stock 488445206 134,911 9,408 SH SOLE 9,408 0 0
ZYMEWORKS INC Common Stock 98985Y108 303,799 11,622 SH SOLE 11,622 0 0
ABIVAX SA-ADR ADR 00370M103 1,229,324 9,225 SH SOLE 9,225 0 0
AUTOLUS THERAPEUTICS PLC ADR 05280R100 51,080 31,925 SH SOLE 31,925 0 0
BICYCLE THERAPEUTICS PLC-ADR ADR 088786108 31,461 7,420 SH SOLE 7,420 0 0
BIONTECH SE-ADR ADR 09075V102 1,720,960 18,495 SH SOLE 18,495 0 0
COMPASS PATHWAYS PLC ADR 20451W101 299,739 21,183 SH SOLE 21,183 0 0
GENMAB A/S -SP ADR ADR 372303206 331,755 12,077 SH SOLE 12,077 0 0
STRUCTURE THERAPEUTICS INC ADR 86366E106 665,991 12,409 SH SOLE 12,409 0 0
GRIFOLS SA-ADR ADR 398438408 137,458 19,415 SH SOLE 19,415 0 0
LEGEND BIOTECH CORP-ADR ADR 52490G102 387,945 13,433 SH SOLE 13,433 0 0
LAKEFRONT BIOTHERAPEUTIC-ADR ADR 36315X101 71,742 2,393 SH SOLE 2,393 0 0
MESOBLAST LTD- SPON ADR ADR 590717401 112,556 8,319 SH SOLE 8,319 0 0
NOVABRIDGE BIOSCIENCES ADR 44975P103 34,835 17,864 SH SOLE 17,864 0 0
BEONE MEDICINES LTD-ADR ADR 07725L102 1,498,087 5,257 SH SOLE 5,257 0 0
SILENCE THERAPEUTICS PLC-ADR ADR 82686Q101 82,076 7,475 SH SOLE 7,475 0 0
SANOFI-ADR ADR 80105N105 1,579,742 37,031 SH SOLE 37,031 0 0
ZAI LAB LTD-ADR ADR 98887Q104 99,560 5,240 SH SOLE 5,240 0 0