| Segment Reporting |
Information about the one reportable segment, significant segment expenses and a reconciliation to condensed consolidated net income is as follows (in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | | | 2026 | | 2025 | | 2026 | | 2025 | | Revenue, net | | $ | 707,331 | | | $ | 603,311 | | | $ | 1,413,935 | | | $ | 1,161,881 | | | Operating expenses: | | | | | | | | | | Direct service costs, excluding depreciation and amortization - Employee compensation | | 163,089 | | | 147,942 | | | 327,692 | | | 291,869 | | | Direct service costs, excluding depreciation and amortization - Other segment items (a) | | 39,466 | | | 37,884 | | | 73,137 | | | 71,773 | | | Reimbursed out-of-pocket expenses | | 303,139 | | | 237,472 | | | 615,143 | | | 439,876 | | | Total direct costs | | 505,694 | | | 423,298 | | | 1,015,972 | | | 803,518 | | | Selling, general and administrative | | 48,103 | | | 46,664 | | | 96,020 | | | 104,561 | | | Depreciation | | 6,555 | | | 6,777 | | | 13,306 | | | 13,471 | | | Amortization | | 155 | | | 237 | | | 310 | | | 473 | | | Total operating expenses | | 560,507 | | | 476,976 | | | 1,125,608 | | | 922,023 | | | Income from operations | | 146,824 | | | 126,335 | | | 288,327 | | | 239,858 | | | Other income (expense), net: | | | | | | | | | | Miscellaneous (expense) income, net | | (147) | | | (2,875) | | | 824 | | | (4,691) | | | Interest income, net | | 4,986 | | | 1,078 | | | 10,103 | | | 7,541 | | | Total other income (expense), net | | 4,839 | | | (1,797) | | | 10,927 | | | 2,850 | | | Income before income taxes | | 151,663 | | | 124,538 | | | 299,254 | | | 242,708 | | | Income tax provision | | 30,301 | | | 34,278 | | | 54,022 | | | 37,853 | | | Segment net income | | $ | 121,362 | | | $ | 90,260 | | | $ | 245,232 | | | $ | 204,855 | | | | | | | | | | | | Reconciliation of profit or loss | | | | | | | | | | Adjustments and reconciling items | | — | | | — | | | — | | | — | | | Condensed consolidated net income | | $ | 121,362 | | | $ | 90,260 | | | $ | 245,232 | | | $ | 204,855 | |
(a) Direct service costs, excluding depreciation and amortization - Other segment items includes costs related to inventory, leases, project subcontractors and other direct service costs.
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| Summary of Revenue by Major Source |
The following table disaggregates the Company’s revenue by major source (in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | | | 2026 | | 2025 | | 2026 | | 2025 | | Therapeutic Area | | | | | | | | | | Metabolic | | $ | 219,067 | | | $ | 147,873 | | | $ | 456,625 | | | $ | 295,888 | | | Oncology | | 209,372 | | | 188,558 | | | 410,611 | | | 359,034 | | | Other | | 98,279 | | | 118,062 | | | 191,597 | | | 213,898 | | | Central Nervous System | | 82,858 | | | 61,129 | | | 163,065 | | | 116,030 | | | Cardiology | | 59,982 | | | 58,584 | | | 116,243 | | | 116,863 | | | AVAI | | 37,773 | | | 29,105 | | | 75,794 | | | 60,168 | | | Total revenue | | $ | 707,331 | | | $ | 603,311 | | | $ | 1,413,935 | | | $ | 1,161,881 | |
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