| Segment Disclosures |
Segment Disclosures Information about the one reportable segment, significant segment expenses and a reconciliation to condensed consolidated net income is as follows (in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | | | 2026 | | 2025 | | 2026 | | 2025 | | Revenue, net | | $ | 707,331 | | | $ | 603,311 | | | $ | 1,413,935 | | | $ | 1,161,881 | | | Operating expenses: | | | | | | | | | | Direct service costs, excluding depreciation and amortization - Employee compensation | | 163,089 | | | 147,942 | | | 327,692 | | | 291,869 | | | Direct service costs, excluding depreciation and amortization - Other segment items (a) | | 39,466 | | | 37,884 | | | 73,137 | | | 71,773 | | | Reimbursed out-of-pocket expenses | | 303,139 | | | 237,472 | | | 615,143 | | | 439,876 | | | Total direct costs | | 505,694 | | | 423,298 | | | 1,015,972 | | | 803,518 | | | Selling, general and administrative | | 48,103 | | | 46,664 | | | 96,020 | | | 104,561 | | | Depreciation | | 6,555 | | | 6,777 | | | 13,306 | | | 13,471 | | | Amortization | | 155 | | | 237 | | | 310 | | | 473 | | | Total operating expenses | | 560,507 | | | 476,976 | | | 1,125,608 | | | 922,023 | | | Income from operations | | 146,824 | | | 126,335 | | | 288,327 | | | 239,858 | | | Other income (expense), net: | | | | | | | | | | Miscellaneous (expense) income, net | | (147) | | | (2,875) | | | 824 | | | (4,691) | | | Interest income, net | | 4,986 | | | 1,078 | | | 10,103 | | | 7,541 | | | Total other income (expense), net | | 4,839 | | | (1,797) | | | 10,927 | | | 2,850 | | | Income before income taxes | | 151,663 | | | 124,538 | | | 299,254 | | | 242,708 | | | Income tax provision | | 30,301 | | | 34,278 | | | 54,022 | | | 37,853 | | | Segment net income | | $ | 121,362 | | | $ | 90,260 | | | $ | 245,232 | | | $ | 204,855 | | | | | | | | | | | | Reconciliation of profit or loss | | | | | | | | | | Adjustments and reconciling items | | — | | | — | | | — | | | — | | | Condensed consolidated net income | | $ | 121,362 | | | $ | 90,260 | | | $ | 245,232 | | | $ | 204,855 | |
(a) Direct service costs, excluding depreciation and amortization - Other segment items includes costs related to inventory, leases, project subcontractors and other direct service costs. Revenue by Category The following table disaggregates the Company’s revenue by major source (in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended June 30, | | Six Months Ended June 30, | | | 2026 | | 2025 | | 2026 | | 2025 | | Therapeutic Area | | | | | | | | | | Metabolic | | $ | 219,067 | | | $ | 147,873 | | | $ | 456,625 | | | $ | 295,888 | | | Oncology | | 209,372 | | | 188,558 | | | 410,611 | | | 359,034 | | | Other | | 98,279 | | | 118,062 | | | 191,597 | | | 213,898 | | | Central Nervous System | | 82,858 | | | 61,129 | | | 163,065 | | | 116,030 | | | Cardiology | | 59,982 | | | 58,584 | | | 116,243 | | | 116,863 | | | AVAI | | 37,773 | | | 29,105 | | | 75,794 | | | 60,168 | | | Total revenue | | $ | 707,331 | | | $ | 603,311 | | | $ | 1,413,935 | | | $ | 1,161,881 | |
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