0001479615 us-gaap:CommonStockMember 2026-07-10 2026-07-10 0001479615 dei:AdrMember 2026-07-10 2026-07-10 0001479615 2026-07-10 2026-07-10 true 0001479615 true 00-0000000 8-K/A 2026-07-10 Silence Therapeutics plc X0 001-39487 12 Hammersmith Grove London GB W6 7AP 44 20 3457 6900 false false false false American Depositary Shares, each representing 3 ordinary shares, nominal value £0.05 per share SLN NASDAQ Ordinary share, nominal value £0.05 per share NASDAQ false This Amendment No. 1 to the Current Report on Form 8-K supplements and amends Item 5.02 of the Current Report on Form 8-K filed on December 15, 2025 (the “Original Form 8-K”) to disclose information regarding material modifications to a material compensatory plan, contract or arrangement as to which a named executive officer of the registrant participates that were effected pursuant to an agreement entered into subsequent to the filing of the Original Form 8-K. No other changes have been made to the Original Form 8-K.