The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108 500,080 19,766 SH SOLE 0 0 19,766
ALKERMES PLC SHS G01767105 314,370 6,000 SH SOLE 0 0 6,000
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 441,009 1,465 SH SOLE 0 0 1,465
AMYLYX PHARMACEUTICALS INC COM 03237H101 194,650 10,838 SH SOLE 0 0 10,838
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 516,534 19,700 SH SOLE 0 0 19,700
ARDELYX INC COM 039697107 306,000 60,000 SH SOLE 0 0 60,000
ARGENX SE SPONSORED ADR 04016X101 594,701 641 SH SOLE 0 0 641
ARRIVENT BIOPHARMA INC COM 04272N102 244,604 7,041 SH SOLE 0 0 7,041
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 211,926 2,600 SH SOLE 0 0 2,600
ASCENDIS PHARMA A/S ORD SHS K08588103 400,080 1,500 SH SOLE 0 0 1,500
AURINIA PHARMACEUTICALS INC COM 05156V102 509,100 30,000 SH SOLE 0 0 30,000
AXSOME THERAPEUTICS INC. COM 05464T104 244,770 1,000 SH SOLE 0 0 1,000
BRIDGEBIO PHARMA INC COM 10806X102 223,440 3,000 SH SOLE 0 0 3,000
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 483,730 13,000 SH SOLE 0 0 13,000
COGENT BIOSCIENCES INC COM 19240Q201 464,400 12,000 SH SOLE 0 0 12,000
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101 254,700 18,000 SH SOLE 0 0 18,000
CRINETICS PHARMACEUTICALS IN COM 22663K107 411,620 11,000 SH SOLE 0 0 11,000
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 272,700 5,000 SH SOLE 0 0 5,000
CYTOMX THERAPEUTICS INC. COM 23284F105 147,750 39,400 SH SOLE 0 0 39,400
DEFINIUM THERAPEUTICS INC COM SHS 24477V105 470,400 10,000 SH SOLE 0 0 10,000
DENALI THERAPEUTICS INC COM 24823R105 217,668 8,463 SH SOLE 0 0 8,463
DIANTHUS THERAPEUTICS INC COM 252828108 243,700 2,500 SH SOLE 0 0 2,500
DISC MEDICINE INC COM 254604101 585,120 8,000 SH SOLE 0 0 8,000
DYNE THERAPEUTICS INC COM 26818M108 444,200 20,000 SH SOLE 0 0 20,000
EDGEWISE THERAPEUTICS INC COM 28036F105 203,150 5,000 SH SOLE 0 0 5,000
ENLIVEN THERAPEUTICS INC COM 29337E102 355,250 7,000 SH SOLE 0 0 7,000
EXELIXIS INC COM 30161Q104 435,280 8,000 SH SOLE 0 0 8,000
EYEPOINT INC COM NEW 30233G209 143,000 10,000 SH SOLE 0 0 10,000
HALOZYME THERAPEUTICS INC COM 40637H109 547,890 7,000 SH SOLE 0 0 7,000
HARMONY BIOSCIENCES HLDGS IN COM 413197104 364,100 10,000 SH SOLE 0 0 10,000
IMMUNOCORE HLDGS PLC ADS 45258D105 480,727 15,141 SH SOLE 0 0 15,141
IMMUNOME INC COM 45257U108 381,420 18,000 SH SOLE 0 0 18,000
IMMUNOVANT INC COM 45258J102 500,890 13,000 SH SOLE 0 0 13,000
INCYTE CORP COM 45337C102 600,808 5,300 SH SOLE 0 0 5,300
INTELLIA THERAPEUTICS INC COM 45826J105 338,400 20,000 SH SOLE 0 0 20,000
IONIS PHARMACEUTICALS INC COM 462222100 539,172 6,800 SH SOLE 0 0 6,800
ISHARES TR 0-3 MTH TREASURY 46436E718 70,469,000 700,000 SH SOLE 0 0 700,000
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 233,982 971 SH SOLE 0 0 971
KINIKSA PHARMACEUTICALS INTL ORD SHS CL A G52694109 319,750 5,000 SH SOLE 0 0 5,000
KODIAK SCIENCES INC COM 50015M109 233,760 6,000 SH SOLE 0 0 6,000
KRYSTAL BIOTECH INC COM 501147102 257,196 692 SH SOLE 0 0 692
KYMERA THERAPEUTICS INC COM 501575104 458,680 4,000 SH SOLE 0 0 4,000
LIQUIDIA CORPORATION COM NEW 53635D202 398,650 5,000 SH SOLE 0 0 5,000
MADRIGAL PHARMACEUTICALS INC COM 558868105 322,170 600 SH SOLE 0 0 600
MIRUM PHARMACEUTICALS INC COM 604749101 292,675 2,500 SH SOLE 0 0 2,500
MONTE ROSA THERAPEUTICS INC COM 61225M102 556,600 23,000 SH SOLE 0 0 23,000
NEUROCRINE BIOSCIENCES INC COM 64125C109 505,605 3,000 SH SOLE 0 0 3,000
NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES N62509109 406,680 12,000 SH SOLE 0 0 12,000
NURIX THERAPEUTICS INC COM 67080M103 606,500 25,000 SH SOLE 0 0 25,000
OCULAR THERAPEUTIX INC COM 67576A100 147,300 15,000 SH SOLE 0 0 15,000
OLEMA PHARMACEUTICALS INC COM 68062P106 125,100 10,000 SH SOLE 0 0 10,000
ORIC PHARMACEUTICALS INC COM 68622P109 140,790 13,000 SH SOLE 0 0 13,000
ORUKA THERAPEUTICS INC COM 687604108 285,510 3,000 SH SOLE 0 0 3,000
PHARVARIS N V COM N69605108 518,700 15,000 SH SOLE 0 0 15,000
PROTAGONIST THERAPEUTICS INC COM 74366E102 367,740 3,000 SH SOLE 0 0 3,000
PTC THERAPEUTICS INC COM 69366J200 489,420 6,000 SH SOLE 0 0 6,000
RAPPORT THERAPEUTICS INC COM 75383L102 583,380 14,000 SH SOLE 0 0 14,000
REVOLUTION MEDICINES INC COM 76155X100 224,736 1,200 SH SOLE 0 0 1,200
RHYTHM PHARMACEUTICALS INC COM 76243J105 222,060 2,000 SH SOLE 0 0 2,000
ROYALTY PHARMA PLC SHS CLASS A G7709Q104 616,770 11,000 SH SOLE 0 0 11,000
SCHOLAR ROCK HLDG CORP COM 80706P103 210,485 3,827 SH SOLE 0 0 3,827
SPDR SERIES TRUST ST STR SP BIOT 78464A870 90,202,500 570,000 SH SOLE 0 0 570,000
SPYRE THERAPEUTICS INC COM NEW 00773J202 355,120 4,000 SH SOLE 0 0 4,000
STOKE THERAPEUTICS INC COM 86150R107 392,640 12,000 SH SOLE 0 0 12,000
SUPERNUS PHARMACEUTICALS COM 868459108 279,060 6,000 SH SOLE 0 0 6,000
SYNDAX PHARMACEUTICALS INC COM 87164F105 437,200 20,000 SH SOLE 0 0 20,000
TANGO THERAPEUTICS INC COM 87583X109 312,600 10,000 SH SOLE 0 0 10,000
TARSUS PHARMACEUTICALS INC COM 87650L103 440,580 7,000 SH SOLE 0 0 7,000
TG THERAPEUTICS INC COM 88322Q108 549,400 10,000 SH SOLE 0 0 10,000
TREVI THERAPEUTICS INC COM 89532M101 559,500 30,000 SH SOLE 0 0 30,000
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 567,630 17,000 SH SOLE 0 0 17,000
VERA THERAPEUTICS INC CL A 92337R101 300,370 7,000 SH SOLE 0 0 7,000
VIKING THERAPEUTICS INC COM 92686J106 390,100 10,000 SH SOLE 0 0 10,000
XENON PHARMACEUTICALS INC COM 98420N105 253,512 4,200 SH SOLE 0 0 4,200
ZYMEWORKS INC COM 98985Y108 261,400 10,000 SH SOLE 0 0 10,000