FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person *
Bejar Rafael

(Last) (First) (Middle)
C/O APTOSE BIOSCIENCES INC.
251 CONSUMERS ROAD, SUITE 1105

(Street)
TORONTO M2J 4R3

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
Aptose Biosciences Inc. [ APTO ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director 10% Owner
Officer (give title below) Other (specify below)
Former SVP&Ch Medical Officer
3. Date of Earliest Transaction (Month/Day/Year)
06/30/2026
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Shares 06/30/2026   D (1)   244 D $ 1.72 (2) 0 D  
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option (Right to Buy) $ 2 06/30/2026   D (1)     35,000   (3) 02/05/2034 Common Shares 35,000 $ 0 0 D  
Employee Stock Option $ 0.66 06/30/2026   D (1)     200,000   (3) 01/19/2033 Common Shares 200,000 $ 0 0 D  
Performance Stock Option $ 2.35 06/30/2026   D (1)     400,000   (4) 08/19/2031 Common Shares 400,000 $ 0 0 D  
Employee Stock Option (Right to Buy) $ 4.37 06/30/2026   D (1)     343,000   (3) 01/04/2031 Common Shares 343,000 $ 0 0 D  
Employee Option Grant $ 6.91 06/30/2026   D (1)     200,000   (3) 01/30/2030 Common Shares 200,000 $ 0 0 D  
Employee Stock Option (Right to Buy) $ 5.67 06/30/2026   D (1)     400,000   (3) 12/31/2030 Common Shares 400,000 $ 0 0 D  
Explanation of Responses:
1. Disposed of pursuant to a board, shareholder and court-approved business arrangement agreement between the Issuer and Hammi Pharmaceuticals Co. Inc., a South Korean corporation ("Hammi") whereby a subsidiary of Hammi acquired all outstanding shares of the Issuer at a price of C$2.41 per share.
2. Converted from Canadian price of C$2.41 per share using an exchange rate of C$1.4 = US$1.00.
3. Options vest 50% on the first anniversary of grant date; remaining options vest 1/3 annually beginning on the second anniversary of the grant date.
4. Performance stock options subject to specific performance criteria.
Remarks:
TOTAL OPTIONS AND OPTION EXERCISE PRICE SUBJECT TO ADJUSTMENT AS A RESULT OF HTE ISSUER'S 1:30 REVERSE STOCK SPLIT ON 2/26/25 AND ISSUER'S 1:15 REVERSE STOCK SPLIT ON 6/6/23
/s/ Rafael Bejar 07/01/2026
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
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