<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:019ef9e5-b251-7c10-85ca-a34b773b0c32,g:9c9dd60b-d219-40be-9470-0ee4e1373ebd-->
<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:mdt="http://www.medtronic.com/20260424" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:dtr-types="http://www.xbrl.org/dtr/type/2024-01-31" attributeFormDefault="unqualified" elementFormDefault="qualified" targetNamespace="http://www.medtronic.com/20260424">
  <xs:import namespace="http://fasb.org/srt/2026" schemaLocation="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd"/>
  <xs:import namespace="http://fasb.org/us-gaap/2026" schemaLocation="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd"/>
  <xs:import namespace="http://www.xbrl.org/2003/instance" schemaLocation="http://www.xbrl.org/2003/xbrl-instance-2003-12-31.xsd"/>
  <xs:import namespace="http://www.xbrl.org/2003/linkbase" schemaLocation="http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd"/>
  <xs:import namespace="http://www.xbrl.org/dtr/type/2024-01-31" schemaLocation="https://www.xbrl.org/dtr/type/2024-01-31/types.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/country/2026" schemaLocation="https://xbrl.sec.gov/country/2026/country-2026.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/cyd-af-sub/2026" schemaLocation="https://xbrl.sec.gov/cyd/2026/cyd-af-sub-2026.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/dei/2026" schemaLocation="https://xbrl.sec.gov/dei/2026/dei-2026.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/ecd/2026" schemaLocation="https://xbrl.sec.gov/ecd/2026/ecd-2026.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/stpr/2026" schemaLocation="https://xbrl.sec.gov/stpr/2026/stpr-2026.xsd"/>
  <xs:annotation>
    <xs:appinfo>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="mdt-20260424_pre.xml" xlink:role="http://www.xbrl.org/2003/role/presentationLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="mdt-20260424_def.xml" xlink:role="http://www.xbrl.org/2003/role/definitionLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="mdt-20260424_lab.xml" xlink:role="http://www.xbrl.org/2003/role/labelLinkbaseRef" xlink:type="simple"/>
      <link:linkbaseRef xmlns:xlink="http://www.w3.org/1999/xlink" xlink:arcrole="http://www.w3.org/1999/xlink/properties/linkbase" xlink:href="mdt-20260424_cal.xml" xlink:role="http://www.xbrl.org/2003/role/calculationLinkbaseRef" xlink:type="simple"/>
      <link:roleType id="Cover" roleURI="http://www.medtronic.com/role/Cover">
        <link:definition>0000001 - Document - Cover</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="AuditInformation" roleURI="http://www.medtronic.com/role/AuditInformation">
        <link:definition>0000002 - Document - Audit Information</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CONSOLIDATEDSTATEMENTSOFOPERATIONS" roleURI="http://www.medtronic.com/role/CONSOLIDATEDSTATEMENTSOFOPERATIONS">
        <link:definition>9952151 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOMELOSS" roleURI="http://www.medtronic.com/role/CONSOLIDATEDSTATEMENTSOFCOMPREHENSIVEINCOMELOSS">
        <link:definition>9952152 - Statement - CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CONSOLIDATEDBALANCESHEETS" roleURI="http://www.medtronic.com/role/CONSOLIDATEDBALANCESHEETS">
        <link:definition>9952153 - Statement - CONSOLIDATED BALANCE SHEETS</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CONSOLIDATEDBALANCESHEETSParenthetical" roleURI="http://www.medtronic.com/role/CONSOLIDATEDBALANCESHEETSParenthetical">
        <link:definition>9952154 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CONSOLIDATEDSTATEMENTSOFSTOCKHOLDERSEQUITY" roleURI="http://www.medtronic.com/role/CONSOLIDATEDSTATEMENTSOFSTOCKHOLDERSEQUITY">
        <link:definition>9952155 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS&#8217; EQUITY</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CONDENSEDCOMBINEDSTATEMENTSOFCASHFLOWS" roleURI="http://www.medtronic.com/role/CONDENSEDCOMBINEDSTATEMENTSOFCASHFLOWS">
        <link:definition>9952156 - Statement - CONDENSED COMBINED STATEMENTS OF CASH FLOWS</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DescriptionoftheBusinessandBasisofPresentation" roleURI="http://www.medtronic.com/role/DescriptionoftheBusinessandBasisofPresentation">
        <link:definition>9952157 - Disclosure - Description of the Business and Basis of Presentation</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SummaryofSignificantAccountingPolicies" roleURI="http://www.medtronic.com/role/SummaryofSignificantAccountingPolicies">
        <link:definition>9952158 - Disclosure - Summary of Significant Accounting Policies</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Revenue" roleURI="http://www.medtronic.com/role/Revenue">
        <link:definition>9952159 - Disclosure - Revenue</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Restructuring" roleURI="http://www.medtronic.com/role/Restructuring">
        <link:definition>9952160 - Disclosure - Restructuring</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CompositionofCertainFinancialStatementItems" roleURI="http://www.medtronic.com/role/CompositionofCertainFinancialStatementItems">
        <link:definition>9952161 - Disclosure - Composition of Certain Financial Statement Items</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancialInstruments" roleURI="http://www.medtronic.com/role/FinancialInstruments">
        <link:definition>9952162 - Disclosure - Financial Instruments</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Debt" roleURI="http://www.medtronic.com/role/Debt">
        <link:definition>9952163 - Disclosure - Debt</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncomeTaxes" roleURI="http://www.medtronic.com/role/IncomeTaxes">
        <link:definition>9952164 - Disclosure - Income Taxes</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockbasedCompensation" roleURI="http://www.medtronic.com/role/StockbasedCompensation">
        <link:definition>9952165 - Disclosure - Stock-based Compensation</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Leases" roleURI="http://www.medtronic.com/role/Leases">
        <link:definition>9952166 - Disclosure - Leases</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ResearchandDevelopmentFundingArrangements" roleURI="http://www.medtronic.com/role/ResearchandDevelopmentFundingArrangements">
        <link:definition>9952167 - Disclosure - Research and Development Funding Arrangements</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CommitmentsandContingencies" roleURI="http://www.medtronic.com/role/CommitmentsandContingencies">
        <link:definition>9952168 - Disclosure - Commitments and Contingencies</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentandGeographicData" roleURI="http://www.medtronic.com/role/SegmentandGeographicData">
        <link:definition>9952169 - Disclosure - Segment and Geographic Data</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RelatedPartyTransactions" roleURI="http://www.medtronic.com/role/RelatedPartyTransactions">
        <link:definition>9952170 - Disclosure - Related Party Transactions</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="Pension" roleURI="http://www.medtronic.com/role/Pension">
        <link:definition>9952171 - Disclosure - Pension</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SummaryofSignificantAccountingPoliciesPolicies" roleURI="http://www.medtronic.com/role/SummaryofSignificantAccountingPoliciesPolicies">
        <link:definition>9955511 - Disclosure - Summary of Significant Accounting Policies (Policies)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SummaryofSignificantAccountingPoliciesTables" roleURI="http://www.medtronic.com/role/SummaryofSignificantAccountingPoliciesTables">
        <link:definition>9955512 - Disclosure - Summary of Significant Accounting Policies (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenueTables" roleURI="http://www.medtronic.com/role/RevenueTables">
        <link:definition>9955513 - Disclosure - Revenue (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RestructuringTables" roleURI="http://www.medtronic.com/role/RestructuringTables">
        <link:definition>9955514 - Disclosure - Restructuring (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CompositionofCertainFinancialStatementItemsTables" roleURI="http://www.medtronic.com/role/CompositionofCertainFinancialStatementItemsTables">
        <link:definition>9955515 - Disclosure - Composition of Certain Financial Statement Items (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancialInstrumentsTables" roleURI="http://www.medtronic.com/role/FinancialInstrumentsTables">
        <link:definition>9955516 - Disclosure - Financial Instruments (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DebtTables" roleURI="http://www.medtronic.com/role/DebtTables">
        <link:definition>9955517 - Disclosure - Debt (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncomeTaxesTables" roleURI="http://www.medtronic.com/role/IncomeTaxesTables">
        <link:definition>9955518 - Disclosure - Income Taxes (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockbasedCompensationTables" roleURI="http://www.medtronic.com/role/StockbasedCompensationTables">
        <link:definition>9955519 - Disclosure - Stock-based Compensation (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesTables" roleURI="http://www.medtronic.com/role/LeasesTables">
        <link:definition>9955520 - Disclosure - Leases (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentandGeographicDataTables" roleURI="http://www.medtronic.com/role/SegmentandGeographicDataTables">
        <link:definition>9955521 - Disclosure - Segment and Geographic Data (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RelatedPartyTransactionsTables" roleURI="http://www.medtronic.com/role/RelatedPartyTransactionsTables">
        <link:definition>9955522 - Disclosure - Related Party Transactions (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PensionTables" roleURI="http://www.medtronic.com/role/PensionTables">
        <link:definition>9955523 - Disclosure - Pension (Tables)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DescriptionoftheBusinessandBasisofPresentationDetails" roleURI="http://www.medtronic.com/role/DescriptionoftheBusinessandBasisofPresentationDetails">
        <link:definition>9955524 - Disclosure - Description of the Business and Basis of Presentation (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SummaryofSignificantAccountingPoliciesCreditLossRollforwardDetails" roleURI="http://www.medtronic.com/role/SummaryofSignificantAccountingPoliciesCreditLossRollforwardDetails">
        <link:definition>9955525 - Disclosure - Summary of Significant Accounting Policies - Credit Loss Rollforward (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SummaryofSignificantAccountingPoliciesNarrativeDetails" roleURI="http://www.medtronic.com/role/SummaryofSignificantAccountingPoliciesNarrativeDetails">
        <link:definition>9955526 - Disclosure - Summary of Significant Accounting Policies - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SummaryofSignificantAccountingPoliciesAntidilutiveSecuritiesDetails" roleURI="http://www.medtronic.com/role/SummaryofSignificantAccountingPoliciesAntidilutiveSecuritiesDetails">
        <link:definition>9955527 - Disclosure - Summary of Significant Accounting Policies - Antidilutive Securities (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenueScheduleofDisaggregationofNetSalesbyMarketGeographyDetails" roleURI="http://www.medtronic.com/role/RevenueScheduleofDisaggregationofNetSalesbyMarketGeographyDetails">
        <link:definition>9955528 - Disclosure - Revenue - Schedule of Disaggregation of Net Sales by Market Geography (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenueScheduleofDisaggregationofNetSalesbyProductDetails" roleURI="http://www.medtronic.com/role/RevenueScheduleofDisaggregationofNetSalesbyProductDetails">
        <link:definition>9955529 - Disclosure - Revenue - Schedule of Disaggregation of Net Sales by Product (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenueNarrativeDetails" roleURI="http://www.medtronic.com/role/RevenueNarrativeDetails">
        <link:definition>9955530 - Disclosure - Revenue - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenueNarrativeDetails_1" roleURI="http://www.medtronic.com/role/RevenueNarrativeDetails_1">
        <link:definition>9955530 - Disclosure - Revenue - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenueNarrativeDetails_2" roleURI="http://www.medtronic.com/role/RevenueNarrativeDetails_2">
        <link:definition>9955530 - Disclosure - Revenue - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RevenueNarrativeDetails_3" roleURI="http://www.medtronic.com/role/RevenueNarrativeDetails_3">
        <link:definition>9955530 - Disclosure - Revenue - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RestructuringNarrativeDetails" roleURI="http://www.medtronic.com/role/RestructuringNarrativeDetails">
        <link:definition>9955531 - Disclosure - Restructuring - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RestructuringNarrativeDetails_1" roleURI="http://www.medtronic.com/role/RestructuringNarrativeDetails_1">
        <link:definition>9955531 - Disclosure - Restructuring - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RestructuringScheduleofRestructuringandRelatedCostsDetails" roleURI="http://www.medtronic.com/role/RestructuringScheduleofRestructuringandRelatedCostsDetails">
        <link:definition>9955532 - Disclosure - Restructuring - Schedule of Restructuring and Related Costs (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RestructuringScheduleofRestructuringandRelatedCostsDetails_1" roleURI="http://www.medtronic.com/role/RestructuringScheduleofRestructuringandRelatedCostsDetails_1">
        <link:definition>9955532 - Disclosure - Restructuring - Schedule of Restructuring and Related Costs (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CompositionofCertainFinancialStatementItemsInventoriesDetails" roleURI="http://www.medtronic.com/role/CompositionofCertainFinancialStatementItemsInventoriesDetails">
        <link:definition>9955533 - Disclosure - Composition of Certain Financial Statement Items - Inventories (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CompositionofCertainFinancialStatementItemsPropertyPlantandEquipmentDetails" roleURI="http://www.medtronic.com/role/CompositionofCertainFinancialStatementItemsPropertyPlantandEquipmentDetails">
        <link:definition>9955534 - Disclosure - Composition of Certain Financial Statement Items - Property, Plant and Equipment (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CompositionofCertainFinancialStatementItemsGoodwillDetails" roleURI="http://www.medtronic.com/role/CompositionofCertainFinancialStatementItemsGoodwillDetails">
        <link:definition>9955535 - Disclosure - Composition of Certain Financial Statement Items - Goodwill (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CompositionofCertainFinancialStatementItemsScheduleofGrossCarryingAmountandAccumulatedAmortizationofDefiniteandIndefiniteLivedIntangibleAssetsDetails" roleURI="http://www.medtronic.com/role/CompositionofCertainFinancialStatementItemsScheduleofGrossCarryingAmountandAccumulatedAmortizationofDefiniteandIndefiniteLivedIntangibleAssetsDetails">
        <link:definition>9955536 - Disclosure - Composition of Certain Financial Statement Items - Schedule of Gross Carrying Amount and Accumulated Amortization of Definite and Indefinite Lived Intangible Assets (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CompositionofCertainFinancialStatementItemsAmortizationExpenseDetails" roleURI="http://www.medtronic.com/role/CompositionofCertainFinancialStatementItemsAmortizationExpenseDetails">
        <link:definition>9955537 - Disclosure - Composition of Certain Financial Statement Items - Amortization Expense (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CompositionofCertainFinancialStatementItemsAmortizationExpenseDetails_1" roleURI="http://www.medtronic.com/role/CompositionofCertainFinancialStatementItemsAmortizationExpenseDetails_1">
        <link:definition>9955537 - Disclosure - Composition of Certain Financial Statement Items - Amortization Expense (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CompositionofCertainFinancialStatementItemsEstimatedAggregateAmortizationExpenseDetails" roleURI="http://www.medtronic.com/role/CompositionofCertainFinancialStatementItemsEstimatedAggregateAmortizationExpenseDetails">
        <link:definition>9955538 - Disclosure - Composition of Certain Financial Statement Items - Estimated Aggregate Amortization Expense (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CompositionofCertainFinancialStatementItemsOtherAccruedExpensesDetails" roleURI="http://www.medtronic.com/role/CompositionofCertainFinancialStatementItemsOtherAccruedExpensesDetails">
        <link:definition>9955539 - Disclosure - Composition of Certain Financial Statement Items - Other Accrued Expenses (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CompositionofCertainFinancialStatementItemsProductWarrantiesDetails" roleURI="http://www.medtronic.com/role/CompositionofCertainFinancialStatementItemsProductWarrantiesDetails">
        <link:definition>9955540 - Disclosure - Composition of Certain Financial Statement Items - Product Warranties (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="FinancialInstrumentsScheduleofEquityandOtherInvestmentsDetails" roleURI="http://www.medtronic.com/role/FinancialInstrumentsScheduleofEquityandOtherInvestmentsDetails">
        <link:definition>9955541 - Disclosure - Financial Instruments - Schedule of Equity and Other Investments (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DebtNarrativeDetails" roleURI="http://www.medtronic.com/role/DebtNarrativeDetails">
        <link:definition>9955542 - Disclosure - Debt - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="DebtSupplierFinancingArrangementsDetails" roleURI="http://www.medtronic.com/role/DebtSupplierFinancingArrangementsDetails">
        <link:definition>9955543 - Disclosure - Debt - Supplier Financing Arrangements (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncomeTaxesComponentsofIncomeLossBeforeIncomeTaxesDetails" roleURI="http://www.medtronic.com/role/IncomeTaxesComponentsofIncomeLossBeforeIncomeTaxesDetails">
        <link:definition>9955544 - Disclosure - Income Taxes - Components of Income (Loss) Before Income Taxes (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncomeTaxesIncomeTaxProvisionDetails" roleURI="http://www.medtronic.com/role/IncomeTaxesIncomeTaxProvisionDetails">
        <link:definition>9955545 - Disclosure - Income Taxes - Income Tax Provision (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncomeTaxesDeferredTaxAssetsandLiabilitiesDetails" roleURI="http://www.medtronic.com/role/IncomeTaxesDeferredTaxAssetsandLiabilitiesDetails">
        <link:definition>9955546 - Disclosure - Income Taxes - Deferred Tax Assets and Liabilities (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncomeTaxesDeferredTaxAssetsandLiabilitiesDetails_1" roleURI="http://www.medtronic.com/role/IncomeTaxesDeferredTaxAssetsandLiabilitiesDetails_1">
        <link:definition>9955546 - Disclosure - Income Taxes - Deferred Tax Assets and Liabilities (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncomeTaxesNarrativeDetails" roleURI="http://www.medtronic.com/role/IncomeTaxesNarrativeDetails">
        <link:definition>9955547 - Disclosure - Income Taxes - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncomeTaxesValuationAllowanceRollforwardDetails" roleURI="http://www.medtronic.com/role/IncomeTaxesValuationAllowanceRollforwardDetails">
        <link:definition>9955548 - Disclosure - Income Taxes - Valuation Allowance Rollforward (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncomeTaxesIncomeTaxPaidDetails" roleURI="http://www.medtronic.com/role/IncomeTaxesIncomeTaxPaidDetails">
        <link:definition>9955549 - Disclosure - Income Taxes - Income Tax Paid (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncomeTaxesEffectiveTaxRateReconciliationDetails" roleURI="http://www.medtronic.com/role/IncomeTaxesEffectiveTaxRateReconciliationDetails">
        <link:definition>9955550 - Disclosure - Income Taxes - Effective Tax Rate Reconciliation (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="IncomeTaxesUnrecognizedTaxBenefitsDetails" roleURI="http://www.medtronic.com/role/IncomeTaxesUnrecognizedTaxBenefitsDetails">
        <link:definition>9955551 - Disclosure - Income Taxes - Unrecognized Tax Benefits (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockbasedCompensationNarrativeDetails" roleURI="http://www.medtronic.com/role/StockbasedCompensationNarrativeDetails">
        <link:definition>9955552 - Disclosure - Stock-based Compensation - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockbasedCompensationShareBasedCompensationExpenseDetails" roleURI="http://www.medtronic.com/role/StockbasedCompensationShareBasedCompensationExpenseDetails">
        <link:definition>9955553 - Disclosure - Stock-based Compensation - Share Based Compensation Expense (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockbasedCompensationShareBasedCompensationExpenseDetails_1" roleURI="http://www.medtronic.com/role/StockbasedCompensationShareBasedCompensationExpenseDetails_1">
        <link:definition>9955553 - Disclosure - Stock-based Compensation - Share Based Compensation Expense (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockbasedCompensationValuationAssumptionsDetails" roleURI="http://www.medtronic.com/role/StockbasedCompensationValuationAssumptionsDetails">
        <link:definition>9955554 - Disclosure - Stock-based Compensation - Valuation Assumptions (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockbasedCompensationStockOptionsActivityDetails" roleURI="http://www.medtronic.com/role/StockbasedCompensationStockOptionsActivityDetails">
        <link:definition>9955555 - Disclosure - Stock-based Compensation - Stock Options Activity (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockbasedCompensationRestrictedStockActivityDetails" roleURI="http://www.medtronic.com/role/StockbasedCompensationRestrictedStockActivityDetails">
        <link:definition>9955556 - Disclosure - Stock-based Compensation - Restricted Stock Activity (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockbasedCompensationPerformanceShareUnitActivityDetails" roleURI="http://www.medtronic.com/role/StockbasedCompensationPerformanceShareUnitActivityDetails">
        <link:definition>9955557 - Disclosure - Stock-based Compensation - Performance Share Unit Activity (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="StockbasedCompensationSharesReservedforFutureInfluenceDetails" roleURI="http://www.medtronic.com/role/StockbasedCompensationSharesReservedforFutureInfluenceDetails">
        <link:definition>9955558 - Disclosure - Stock-based Compensation - Shares Reserved for Future Influence (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesBalanceSheetClassificationandAmountsofRightofUseAssetsandLeaseLiabilitiesDetails" roleURI="http://www.medtronic.com/role/LeasesBalanceSheetClassificationandAmountsofRightofUseAssetsandLeaseLiabilitiesDetails">
        <link:definition>9955559 - Disclosure - Leases - Balance Sheet Classification and Amounts of Right-of-Use Assets and Lease Liabilities (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesWeightedAverageRemainingLeaseTermandWeightedAverageDiscountRateforOperatingLeasesDetails" roleURI="http://www.medtronic.com/role/LeasesWeightedAverageRemainingLeaseTermandWeightedAverageDiscountRateforOperatingLeasesDetails">
        <link:definition>9955560 - Disclosure - Leases - Weighted-Average Remaining Lease Term and Weighted-Average Discount Rate for Operating Leases (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesSupplementalCashFlowInformationDetails" roleURI="http://www.medtronic.com/role/LeasesSupplementalCashFlowInformationDetails">
        <link:definition>9955561 - Disclosure - Leases - Supplemental Cash Flow Information (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesMaturitiesofOperatingLeasesDetails" roleURI="http://www.medtronic.com/role/LeasesMaturitiesofOperatingLeasesDetails">
        <link:definition>9955562 - Disclosure - Leases - Maturities of Operating Leases (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="LeasesMaturitiesofOperatingLeasesDetails_1" roleURI="http://www.medtronic.com/role/LeasesMaturitiesofOperatingLeasesDetails_1">
        <link:definition>9955562 - Disclosure - Leases - Maturities of Operating Leases (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="ResearchandDevelopmentFundingArrangementsDetails" roleURI="http://www.medtronic.com/role/ResearchandDevelopmentFundingArrangementsDetails">
        <link:definition>9955563 - Disclosure - Research and Development Funding Arrangements (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="CommitmentsandContingenciesDetails" roleURI="http://www.medtronic.com/role/CommitmentsandContingenciesDetails">
        <link:definition>9955564 - Disclosure - Commitments and Contingencies (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentandGeographicDataNarrativeDetails" roleURI="http://www.medtronic.com/role/SegmentandGeographicDataNarrativeDetails">
        <link:definition>9955565 - Disclosure - Segment and Geographic Data - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="SegmentandGeographicDataScheduleofNetSalestoExternalCustomersbyGeographyDetails" roleURI="http://www.medtronic.com/role/SegmentandGeographicDataScheduleofNetSalestoExternalCustomersbyGeographyDetails">
        <link:definition>9955566 - Disclosure - Segment and Geographic Data - Schedule of Net Sales to External Customers by Geography (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RelatedPartyTransactionsNarrativeDetails" roleURI="http://www.medtronic.com/role/RelatedPartyTransactionsNarrativeDetails">
        <link:definition>9955567 - Disclosure - Related Party Transactions - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RelatedPartyTransactionsSharedExpensesWithParentDetails" roleURI="http://www.medtronic.com/role/RelatedPartyTransactionsSharedExpensesWithParentDetails">
        <link:definition>9955568 - Disclosure - Related Party Transactions - Shared Expenses With Parent (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="RelatedPartyTransactionsNetTransfersWithParentDetails" roleURI="http://www.medtronic.com/role/RelatedPartyTransactionsNetTransfersWithParentDetails">
        <link:definition>9955569 - Disclosure - Related Party Transactions - Net Transfers With Parent (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PensionNarrativeDetails" roleURI="http://www.medtronic.com/role/PensionNarrativeDetails">
        <link:definition>9955570 - Disclosure - Pension - Narrative (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PensionChangeinBenefitObligationandFundedStatusDetails" roleURI="http://www.medtronic.com/role/PensionChangeinBenefitObligationandFundedStatusDetails">
        <link:definition>9955571 - Disclosure - Pension - Change in Benefit Obligation and Funded Status (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PensionBenefitObligationinExcessofPlanAssetsDetails" roleURI="http://www.medtronic.com/role/PensionBenefitObligationinExcessofPlanAssetsDetails">
        <link:definition>9955572 - Disclosure - Pension - Benefit Obligation in Excess of Plan Assets (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PensionActuarialAssumptionsandPlanAssetsTargetAllocationsDetails" roleURI="http://www.medtronic.com/role/PensionActuarialAssumptionsandPlanAssetsTargetAllocationsDetails">
        <link:definition>9955573 - Disclosure - Pension - Actuarial Assumptions and Plan Assets Target Allocations (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PensionFutureBenefitPaymentsDetails" roleURI="http://www.medtronic.com/role/PensionFutureBenefitPaymentsDetails">
        <link:definition>9955574 - Disclosure - Pension - Future Benefit Payments (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PensionNetPeriodicCostandAOCIDetails" roleURI="http://www.medtronic.com/role/PensionNetPeriodicCostandAOCIDetails">
        <link:definition>9955575 - Disclosure - Pension - Net Periodic Cost and AOCI (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
      <link:roleType id="PensionFairValueMeasurementDetails" roleURI="http://www.medtronic.com/role/PensionFairValueMeasurementDetails">
        <link:definition>9955576 - Disclosure - Pension - Fair Value Measurement (Details)</link:definition>
        <link:usedOn>link:presentationLink</link:usedOn>
        <link:usedOn>link:calculationLink</link:usedOn>
        <link:usedOn>link:definitionLink</link:usedOn>
      </link:roleType>
    </xs:appinfo>
  </xs:annotation>
  <xs:element id="mdt_AuditInformationAbstract" abstract="true" name="AuditInformationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="mdt_NetInvestmentFromParent" abstract="false" name="NetInvestmentFromParent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_ParentCompanyInvestmentMember" abstract="true" name="ParentCompanyInvestmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_AdjustmentsToAdditionalPaidInCapitalDistributionToParentInConnectionWithSeparation" abstract="false" name="AdjustmentsToAdditionalPaidInCapitalDistributionToParentInConnectionWithSeparation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_StockholdersEquityNetTransfersFromToParent" abstract="false" name="StockholdersEquityNetTransfersFromToParent" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_AdjustmentsToAdditionalPaidInCapitalReclassificationOfNetParentInvestment" abstract="false" name="AdjustmentsToAdditionalPaidInCapitalReclassificationOfNetParentInvestment" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_IncreaseDecreaseInCollaborativeArrangementsRightsAndObligationsRoyaltyLiabilities" abstract="false" name="IncreaseDecreaseInCollaborativeArrangementsRightsAndObligationsRoyaltyLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_CapitalizedExpensesInAccountsPayableAndAccruedLiabilities" abstract="false" name="CapitalizedExpensesInAccountsPayableAndAccruedLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_OtherOperatingIncomeExpensePolicyPolicyTextBlock" abstract="false" name="OtherOperatingIncomeExpensePolicyPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="mdt_OtherNonoperatingIncomeExpensePolicyPolicyTextBlock" abstract="false" name="OtherNonoperatingIncomeExpensePolicyPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="mdt_AssetsAndLiabilitiesLesseeTableTextBlock" abstract="false" name="AssetsAndLiabilitiesLesseeTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="mdt_AllocatedExpensesWithParentCompanyMember" abstract="true" name="AllocatedExpensesWithParentCompanyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_PumpsAndConsumablesMember" abstract="true" name="PumpsAndConsumablesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_PumpsMember" abstract="true" name="PumpsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_ConsumablesMember" abstract="true" name="ConsumablesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_ContinuousGlucoseMonitoringSystemsCGMMember" abstract="true" name="ContinuousGlucoseMonitoringSystemsCGMMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_IncreaseDecreaseInContractWithCustomerRefundLiability" abstract="false" name="IncreaseDecreaseInContractWithCustomerRefundLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_TerminationOfThirdPartyManufacturingAgreementMember" abstract="true" name="TerminationOfThirdPartyManufacturingAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_AssetWriteOffMember" abstract="true" name="AssetWriteOffMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_BuildingAndLeaseholdImprovementsMember" abstract="true" name="BuildingAndLeaseholdImprovementsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_PurchasedTechnologyAndPatentsMember" abstract="true" name="PurchasedTechnologyAndPatentsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_ContractTerminationLiabilityCurrent" abstract="false" name="ContractTerminationLiabilityCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_AncillaryServicesLiabilityCurrent" abstract="false" name="AncillaryServicesLiabilityCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_MedtronicDiabetesBusinessMember" abstract="true" name="MedtronicDiabetesBusinessMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_SupplierFinanceProgramObligationNet" abstract="false" name="SupplierFinanceProgramObligationNet" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_SupplierFinanceProgramObligationAdjustments" abstract="false" name="SupplierFinanceProgramObligationAdjustments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_DeferredTaxAssetsOperatingLossCapitalLossAndTaxCreditCarryforwards" abstract="false" name="DeferredTaxAssetsOperatingLossCapitalLossAndTaxCreditCarryforwards" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_DeferredTaxAssetsCapitalizedResearchAndDevelopment" abstract="false" name="DeferredTaxAssetsCapitalizedResearchAndDevelopment" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_DeferredTaxAssetsLeaseObligations" abstract="false" name="DeferredTaxAssetsLeaseObligations" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_DeferredTaxAssetsOtherNoncurrentNet" abstract="false" name="DeferredTaxAssetsOtherNoncurrentNet" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_DeferredTaxLiabilitiesOtherNet" abstract="false" name="DeferredTaxLiabilitiesOtherNet" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_DepartamentoDeHaciendaPuertoRicoMember" abstract="true" name="DepartamentoDeHaciendaPuertoRicoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_TaxCreditCarryforwardNoExpirationAmount" abstract="false" name="TaxCreditCarryforwardNoExpirationAmount" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_EffectiveIncomeTaxRateReconciliationPillar2Amount" abstract="false" name="EffectiveIncomeTaxRateReconciliationPillar2Amount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_ValuationAllowanceDeferredTaxAssetChargedToCostAndExpenseAmount" abstract="false" name="ValuationAllowanceDeferredTaxAssetChargedToCostAndExpenseAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_ValuationAllowanceDeferredTaxAssetChargeToOtherAccountAmount" abstract="false" name="ValuationAllowanceDeferredTaxAssetChargeToOtherAccountAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_EffectiveIncomeTaxRateReconciliationWithholdingTaxesAmount" abstract="false" name="EffectiveIncomeTaxRateReconciliationWithholdingTaxesAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_EffectiveIncomeTaxRateReconciliationPillar2Percent" abstract="false" name="EffectiveIncomeTaxRateReconciliationPillar2Percent" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mdt_EffectiveIncomeTaxRateReconciliationWithholdingTaxesPercent" abstract="false" name="EffectiveIncomeTaxRateReconciliationWithholdingTaxesPercent" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mdt_UnrecognizedTaxBenefitsBeforeAdjustmentsWithParentCompany" abstract="false" name="UnrecognizedTaxBenefitsBeforeAdjustmentsWithParentCompany" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_UnrecognizedTaxBenefitsDecreaseResultingFromSettlementsWithParent" abstract="false" name="UnrecognizedTaxBenefitsDecreaseResultingFromSettlementsWithParent" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_IPOGrantsMember" abstract="true" name="IPOGrantsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_MiniMedGroupInc.2026LongTermIncentivePlanMember" abstract="true" name="MiniMedGroupInc.2026LongTermIncentivePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_ShareBasedCompensationArrangementByShareBasedPaymentAwardPurchasePeriod" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardPurchasePeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="mdt_MedtronicCorporateAndShareEmployeesMember" abstract="true" name="MedtronicCorporateAndShareEmployeesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_Medtronic2021PlanMember" abstract="true" name="Medtronic2021PlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsConveyanceChangeInPeriod" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsConveyanceChangeInPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mdt_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsConvertedInPeriod" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsConvertedInPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mdt_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsConveyanceChangeInPeriodWeightedAverageGrantDateFairValue" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsConveyanceChangeInPeriodWeightedAverageGrantDateFairValue" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="mdt_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsConvertedInPeriodWeightedAverageGrantDateFairValue" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsConvertedInPeriodWeightedAverageGrantDateFairValue" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="mdt_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsPerformanceAdjustmentsInPeriod" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsPerformanceAdjustmentsInPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="mdt_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsPerformanceAdjustmentsInPeriodWeightedAverageGrantDateFairValue" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsPerformanceAdjustmentsInPeriodWeightedAverageGrantDateFairValue" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="mdt_RSUsAndPSUsMember" abstract="true" name="RSUsAndPSUsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_BlackstoneArrangementSpecificDiabetesProductsMember" abstract="true" name="BlackstoneArrangementSpecificDiabetesProductsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_BlackstoneArrangementSpecificDiabetesProductsMiniMedFitPatchPumpMember" abstract="true" name="BlackstoneArrangementSpecificDiabetesProductsMiniMedFitPatchPumpMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_BlackstoneArrangementSpecificDiabetesProductsMiniMedFlexInsulinPumpMember" abstract="true" name="BlackstoneArrangementSpecificDiabetesProductsMiniMedFlexInsulinPumpMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_BlackstoneArrangementCoDevelopmentArrangementsMember" abstract="true" name="BlackstoneArrangementCoDevelopmentArrangementsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_BlackstoneMember" abstract="true" name="BlackstoneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_RevenueFromCollaborativeArrangementExcludingRevenueFromContractWithCustomerRevenueRecognized" abstract="false" name="RevenueFromCollaborativeArrangementExcludingRevenueFromContractWithCustomerRevenueRecognized" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_CollaborativeArrangementRightsAndObligationsRoyaltyPayment" abstract="false" name="CollaborativeArrangementRightsAndObligationsRoyaltyPayment" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_CollaborativeArrangementRoyaltyPaymentTerm1" abstract="false" name="CollaborativeArrangementRoyaltyPaymentTerm1" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="mdt_CollaborativeArrangementRoyaltyPaymentTerm2" abstract="false" name="CollaborativeArrangementRoyaltyPaymentTerm2" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="mdt_CollaborativeArrangementRoyaltyPaymentTerm3" abstract="false" name="CollaborativeArrangementRoyaltyPaymentTerm3" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="mdt_CollaborativeArrangementRightsAndObligationsContractTerminationFee" abstract="false" name="CollaborativeArrangementRightsAndObligationsContractTerminationFee" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_CollaborativeArrangementNumberOfContractsTerminated" abstract="false" name="CollaborativeArrangementNumberOfContractsTerminated" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="mdt_DiabetesPumpRetainerRingLitigationMember" abstract="true" name="DiabetesPumpRetainerRingLitigationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_EOFlowInternationalArbitrationMember" abstract="true" name="EOFlowInternationalArbitrationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_EOFlowCo.Ltd.Member" abstract="true" name="EOFlowCo.Ltd.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_MinimedGroupIncMember" abstract="true" name="MinimedGroupIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_MedtronicPlcMember" abstract="true" name="MedtronicPlcMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_TransitionServicesAgreementsProvidedToMedtronicMember" abstract="true" name="TransitionServicesAgreementsProvidedToMedtronicMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_TransitionServicesAgreementsProvidedByMedtronicMember" abstract="true" name="TransitionServicesAgreementsProvidedByMedtronicMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_AmountsDueFromParentCompanyMember" abstract="true" name="AmountsDueFromParentCompanyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_AmountsDueToParentCompanyMember" abstract="true" name="AmountsDueToParentCompanyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="mdt_RelatedPartyTransactionOtherIncomeExpense" abstract="false" name="RelatedPartyTransactionOtherIncomeExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_DefinedBenefitPlanBenefitObligationTransfersFromParent" abstract="false" name="DefinedBenefitPlanBenefitObligationTransfersFromParent" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="mdt_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostInterestRate" abstract="false" name="DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostInterestRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mdt_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostServiceCostDiscountRate" abstract="false" name="DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostServiceCostDiscountRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mdt_DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostInterestCostDiscountRate" abstract="false" name="DefinedBenefitPlanAssumptionsUsedCalculatingNetPeriodicBenefitCostInterestCostDiscountRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="mdt_DefinedBenefitPlanRegisteredInvestmentCompaniesMember" abstract="true" name="DefinedBenefitPlanRegisteredInvestmentCompaniesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
