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  <xs:element id="jnj_RealAssetsMember" abstract="true" name="RealAssetsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_PrivateCreditMember" abstract="true" name="PrivateCreditMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_CommonCollectiveTrustU.S.EquitiesMember" abstract="true" name="CommonCollectiveTrustU.S.EquitiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_CommonCollectiveTrustGlobalEquitiesAndEmergingMarketsMember" abstract="true" name="CommonCollectiveTrustGlobalEquitiesAndEmergingMarketsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_CommonCollectiveTrustFixedIncomeMember" abstract="true" name="CommonCollectiveTrustFixedIncomeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_LimitedPartnershipsEmergingMarketLongOnlyEquityFundsMember" abstract="true" name="LimitedPartnershipsEmergingMarketLongOnlyEquityFundsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_LimitedPartnershipsPrivateMarketFundsMember" abstract="true" name="LimitedPartnershipsPrivateMarketFundsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_InvestmentStrategyAxis" abstract="true" name="InvestmentStrategyAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="jnj_InvestmentStrategyDomain" abstract="true" name="InvestmentStrategyDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_PassiveMember" abstract="true" name="PassiveMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_ActiveMember" abstract="true" name="ActiveMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_CoInvestmentsMember" abstract="true" name="CoInvestmentsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_EBPInvestmentPlanInterestInMasterTrustFairAndContractValuePercent" abstract="false" name="EBPInvestmentPlanInterestInMasterTrustFairAndContractValuePercent" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="jnj_EBPInvestmentPlanInterestInMasterTrustFairAndContractValueExtensionTerms" abstract="false" name="EBPInvestmentPlanInterestInMasterTrustFairAndContractValueExtensionTerms" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="jnj_EBPDerivativeAsset" abstract="false" name="EBPDerivativeAsset" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="jnj_EBPDerivativeLiability" abstract="false" name="EBPDerivativeLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="jnj_MaturityAxis" abstract="true" name="MaturityAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="jnj_MaturityDomain" abstract="true" name="MaturityDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_MaturityOfOneYearMember" abstract="true" name="MaturityOfOneYearMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_MaturityOfTwoYearsMember" abstract="true" name="MaturityOfTwoYearsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_MaturityOfThreeYearsMember" abstract="true" name="MaturityOfThreeYearsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_MaturityOfFourYearsMember" abstract="true" name="MaturityOfFourYearsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_MaturityOfFiveYearsMember" abstract="true" name="MaturityOfFiveYearsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_MaturityOfSixYearsMember" abstract="true" name="MaturityOfSixYearsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_MaturityOfSevenYearsMember" abstract="true" name="MaturityOfSevenYearsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_MaturityOfEightYearsMember" abstract="true" name="MaturityOfEightYearsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_MaturityOfNineYearsMember" abstract="true" name="MaturityOfNineYearsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_MaturityOfTenYearsMember" abstract="true" name="MaturityOfTenYearsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_EBPDerivativeNumberOfContracts" abstract="false" name="EBPDerivativeNumberOfContracts" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="jnj_EBPCustodianMember" abstract="true" name="EBPCustodianMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="jnj_EBPPlannedBusinessSeparationTerm" abstract="false" name="EBPPlannedBusinessSeparationTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
</xs:schema>
