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        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
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        <fairValLevel>1</fairValLevel>
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        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
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        <fairValLevel>1</fairValLevel>
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        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
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        <fairValLevel>1</fairValLevel>
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        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
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        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
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        <fairValLevel>1</fairValLevel>
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        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
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        <name>N/A</name>
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        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>2</fairValLevel>
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        <name>CRINETICS PHARMACEUTICALS INC</name>
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        <title>Crinetics Pharmaceuticals, Inc. </title>
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        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
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        <name>ALTO NEUROSCIENCE INC</name>
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        <fairValLevel>1</fairValLevel>
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        <title>Terns Pharmaceuticals, Inc. </title>
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        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
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        <name>OMEROS CORP</name>
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        <name>ELI LILLY &amp; COMPANY</name>
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        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
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        <isRestrictedSec>N</isRestrictedSec>
        
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        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>2</fairValLevel>
        <repurchaseAgrmt>
          <transCat>Repurchase</transCat>
          <notClearedCentCparty isCleared="N">
            <counterpartyInfos>
              <counterpartyInfo lei="5493004J7H4GCPG6OB62" name="CF Secured"/>
            </counterpartyInfos>
          </notClearedCentCparty>
          <isTriParty>Y</isTriParty>
          <repurchaseRt>3.52000000</repurchaseRt>
          <maturityDt>2026-05-01</maturityDt>
          <repurchaseCollaterals>
            <repurchaseCollateral>
              <principalAmt>188000.00000000</principalAmt>
              <principalCd>USD</principalCd>
              <collateralVal>188818.33000000</collateralVal>
              <collateralCd>USD</collateralCd>
              <invstCat>UST</invstCat>
            </repurchaseCollateral>
          </repurchaseCollaterals>
        </repurchaseAgrmt>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PRESTIGE CONSUMER HEALTHCARE INC</name>
        <lei>N/A</lei>
        <title>Prestige Consumer Healthcare, Inc. </title>
        <cusip>74112D101</cusip>
        <identifiers>
          <isin value="US74112D1019"/>
        </identifiers>
        <balance>685.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>38579.20000000</valUSD>
        <pctVal>1.144857754379</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ALUMIS INC</name>
        <lei>N/A</lei>
        <title>Alumis, Inc. </title>
        <cusip>022307102</cusip>
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          <isin value="US0223071020"/>
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        <balance>1686.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>41627.34000000</valUSD>
        <pctVal>1.235312888634</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
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        <name>PFIZER INC</name>
        <lei>765LHXWGK1KXCLTFYQ30</lei>
        <title>Pfizer, Inc. </title>
        <cusip>717081103</cusip>
        <identifiers>
          <isin value="US7170811035"/>
        </identifiers>
        <balance>1626.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>43414.20000000</valUSD>
        <pctVal>1.288338885207</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>N/A</name>
        <lei>N/A</lei>
        <title>PHPIX_SPSIPH_GOLDMAN</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Dummy ID" value="1076GSWPS"/>
        </identifiers>
        <balance>-30.00000000</balance>
        <units>OU</units>
        <curCd>USD</curCd>
        <valUSD>32.93000000</valUSD>
        <pctVal>0.000977214816</pctVal>
        <payoffProfile>Short</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="Total Return Swap" issuerCat="OTHER"/>
        <invCountry>US</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>2</fairValLevel>
        <derivativeInfo>
          <swapDeriv derivCat="SWP">
            <counterparties>
              <counterpartyName>GOLDMAN SACHS GROUP, INC.</counterpartyName>
              <counterpartyLei>784F5XWPLTWKTBV3E584</counterpartyLei>
            </counterparties>
            <descRefInstrmnt>
              <indexBasketInfo>
                <indexName>DOW JONES U.S. SELECT PHARMACEUTICALS INDEX</indexName>
                <indexIdentifier>SPSIPH Index</indexIdentifier>
                <narrativeDesc>This swap is not based on custom baskets or indices</narrativeDesc>
              </indexBasketInfo>
            </descRefInstrmnt>
            <swapFlag>Y</swapFlag>
            <floatingRecDesc curCd="USD" fixedOrFloating="Floating" floatingRtIndex="FEDL01" floatingRtSpread="0.00750000" pmntAmt="-30.00000000">
              <rtResetTenors>
                <rtResetTenor rateTenor="Month" rateTenorUnit="1" resetDt="Month" resetDtUnit="1"/>
              </rtResetTenors>
            </floatingRecDesc>
            <otherPmntDesc fixedOrFloating="Other">DOW JONES U.S. SELECT PHARMACEUTICALS INDEX</otherPmntDesc>
            <terminationDt>2026-05-26</terminationDt>
            <upfrontPmnt>0.00000000</upfrontPmnt>
            <pmntCurCd>USD</pmntCurCd>
            <upfrontRcpt>0.00000000</upfrontRcpt>
            <rcptCurCd>USD</rcptCurCd>
            <notionalAmt>-198112.80000000</notionalAmt>
            <curCd>USD</curCd>
            <unrealizedAppr>32.93000000</unrealizedAppr>
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        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ANI PHARMACEUTICALS INC</name>
        <lei>5493000T6CXTND40YH31</lei>
        <title>ANI Pharmaceuticals, Inc. </title>
        <cusip>00182C103</cusip>
        <identifiers>
          <isin value="US00182C1036"/>
        </identifiers>
        <balance>582.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>46239.90000000</valUSD>
        <pctVal>1.372192997178</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>LB PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>LB Pharmaceuticals, Inc. </title>
        <cusip>50180M108</cusip>
        <identifiers>
          <isin value="US50180M1080"/>
        </identifiers>
        <balance>671.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>21277.41000000</valUSD>
        <pctVal>0.631418169158</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>JAZZ PHARMACEUTICALS PLC</name>
        <lei>635400GAUMJCLEZRRV50</lei>
        <title>Jazz Pharmaceuticals plc </title>
        <cusip>G50871105</cusip>
        <identifiers>
          <isin value="IE00B4Q5ZN47"/>
        </identifiers>
        <balance>239.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>48521.78000000</valUSD>
        <pctVal>1.439908968804</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>XERIS BIOPHARMA HOLDINGS INC</name>
        <lei>N/A</lei>
        <title>Xeris Biopharma Holdings, Inc. </title>
        <cusip>98422E103</cusip>
        <identifiers>
          <isin value="US98422E1038"/>
        </identifiers>
        <balance>7337.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>44939.13000000</valUSD>
        <pctVal>1.333591973280</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PHIBRO ANIMAL HEALTH CORP</name>
        <lei>549300U24SP4AF2JUX52</lei>
        <title>Phibro Animal Health Corporation </title>
        <cusip>71742Q106</cusip>
        <identifiers>
          <isin value="US71742Q1067"/>
        </identifiers>
        <balance>749.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>39831.82000000</valUSD>
        <pctVal>1.182029902073</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MAZE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>Maze Therapeutics, Inc. </title>
        <cusip>578784100</cusip>
        <identifiers>
          <isin value="US5787841007"/>
        </identifiers>
        <balance>880.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>23390.40000000</valUSD>
        <pctVal>0.694122242504</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>N/A</name>
        <lei>N/A</lei>
        <title>ROYAL BANK OF CANADA  3.42 , 5/01/2026</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Dummy ID" value="RBC26501"/>
        </identifiers>
        <balance>42000.00000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>42000.00000000</valUSD>
        <pctVal>1.246371767272</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>RA</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        
        <fairValLevel>2</fairValLevel>
        <repurchaseAgrmt>
          <transCat>Repurchase</transCat>
          <notClearedCentCparty isCleared="N">
            <counterpartyInfos>
              <counterpartyInfo lei="ES7IP3U3RHIGC71XBU11" name="ROYAL BANK OF CANADA"/>
            </counterpartyInfos>
          </notClearedCentCparty>
          <isTriParty>Y</isTriParty>
          <repurchaseRt>3.42000000</repurchaseRt>
          <maturityDt>2026-05-01</maturityDt>
          <repurchaseCollaterals>
            <repurchaseCollateral>
              <principalAmt>42400.00000000</principalAmt>
              <principalCd>USD</principalCd>
              <collateralVal>42939.51000000</collateralVal>
              <collateralCd>USD</collateralCd>
              <invstCat>UST</invstCat>
            </repurchaseCollateral>
          </repurchaseCollaterals>
        </repurchaseAgrmt>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <signature>
      <ncom:dateSigned>2026-04-30</ncom:dateSigned>
      <ncom:nameOfApplicant>Pharmaceuticals UltraSector ProFund</ncom:nameOfApplicant>
      <ncom:signature>Rebecca Colvin </ncom:signature>
      <ncom:signerName>Rebecca Colvin </ncom:signerName>
      <ncom:title>Treasurer and Principal Financial Officer </ncom:title>
    </signature>
  </formData>
  <documents>XXXX</documents>
</edgarSubmission>
