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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValue_019e1cf6-953b-7b20-8419-7f3093c7109d_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investments, at fair value:</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValue_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValue" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValue"/>
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    <link:label id="lab_csx_EBPNoteReceivableFromParticipantGeneralLoanBorrowingTerm_label_en-US" xlink:label="lab_csx_EBPNoteReceivableFromParticipantGeneralLoanBorrowingTerm" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable From Participant, General Loan, Borrowing Term</link:label>
    <link:label id="lab_csx_EBPNoteReceivableFromParticipantGeneralLoanBorrowingTerm_documentation_en-US" xlink:label="lab_csx_EBPNoteReceivableFromParticipantGeneralLoanBorrowingTerm" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable From Participant, General Loan, Borrowing Term</link:label>
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    <link:label id="lab_srt_MaximumMember_label_en-US" xlink:label="lab_srt_MaximumMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Maximum [Member]</link:label>
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    <link:label id="lab_dei_LegalEntityAxis_019e1cf6-95dd-776d-9cf8-03868ec87300_terseLabel_en-US" xlink:label="lab_dei_LegalEntityAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Legal Entity [Axis]</link:label>
    <link:label id="lab_dei_LegalEntityAxis_label_en-US" xlink:label="lab_dei_LegalEntityAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Legal Entity [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LegalEntityAxis" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_LegalEntityAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_LegalEntityAxis" xlink:to="lab_dei_LegalEntityAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_RangeMember_019e1cf6-95dd-7fa1-a0bd-db714ce81c9d_terseLabel_en-US" xlink:label="lab_srt_RangeMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Statistical Measurement [Domain]</link:label>
    <link:label id="lab_srt_RangeMember_label_en-US" xlink:label="lab_srt_RangeMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Statistical Measurement [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_RangeMember" xlink:to="lab_srt_RangeMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable_019e1cf6-953b-7d2e-8aa3-78c8197548c7_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Description of Plan [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Description of Plan [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTable"/>
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    <link:label id="lab_us-gaap_MutualFundMember_019e1cf6-953b-79a1-abbf-5410d3c103c7_terseLabel_en-US" xlink:label="lab_us-gaap_MutualFundMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Mutual Funds</link:label>
    <link:label id="lab_us-gaap_MutualFundMember_label_en-US" xlink:label="lab_us-gaap_MutualFundMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Mutual Fund [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MutualFundMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_MutualFundMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_MutualFundMember" xlink:to="lab_us-gaap_MutualFundMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable_019e1cf6-95dd-7e66-8359-90fd7f60cef9_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Related Party and Party-in-Interest Transactions [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Related Party and Party-in-Interest Transactions [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleTable_019e1cf6-95dd-700c-a437-e674833125f3_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Accounting Standard Update and Change in Accounting Principle [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleTable_label_en-US" xlink:label="lab_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Accounting Standard Update and Change in Accounting Principle [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleTable" xlink:to="lab_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable_019e1cf6-953b-7c6b-8a3b-abe191885643_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Fully Benefit-Responsive Investment Contract [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Fully Benefit-Responsive Investment Contract [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTable"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease_019e1cf6-95dd-7767-9955-b149433d3ea3_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Total Deductions</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Decrease</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecrease"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount_019e1cf6-95dd-7bcb-815c-75dde616948f_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Maximum borrowing, amount</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable from Participant, Account, Maximum Borrowing, Amount</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingAmount"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTextBlock_019e1cf6-95dd-7ad8-8f1f-624546938293_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Fair Value Measurements</link:label>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAccruedExpense_019e1cf6-95dd-7d2b-858a-66a79a5d075b_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAccruedExpense" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Accrued expenses</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractAbstract"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedPlanInterestInMasterTrustMember_019e1cf6-953b-7c7a-b9cd-1e96467292e3_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedPlanInterestInMasterTrustMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Nonconsolidated, Plan Interest in Master Trust</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedPlanInterestInMasterTrustMember_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedPlanInterestInMasterTrustMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Nonconsolidated, Plan Interest in Master Trust [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedPlanInterestInMasterTrustMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedPlanInterestInMasterTrustMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedPlanInterestInMasterTrustMember" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedPlanInterestInMasterTrustMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueInputsLevel1Member_019e1cf6-95dd-76f0-9c60-d368096a6931_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel1Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Level 1</link:label>
    <link:label id="lab_us-gaap_FairValueInputsLevel1Member_label_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel1Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Fair Value, Inputs, Level 1 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueInputsLevel1Member" xlink:to="lab_us-gaap_FairValueInputsLevel1Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock_019e1cf6-95dd-78a6-af2b-6b48b2123dbd_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Fully Benefit-Responsive Investment Contracts</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Fully Benefit-Responsive Investment Contract [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value and NAV [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_csx_EBPInvoluntaryRolloverLimit_019e1cf6-95dd-7eb3-9684-191d97de2cd5_terseLabel_en-US" xlink:label="lab_csx_EBPInvoluntaryRolloverLimit" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Involuntary rollover limit</link:label>
    <link:label id="lab_csx_EBPInvoluntaryRolloverLimit_label_en-US" xlink:label="lab_csx_EBPInvoluntaryRolloverLimit" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Involuntary Rollover Limit</link:label>
    <link:label id="lab_csx_EBPInvoluntaryRolloverLimit_documentation_en-US" xlink:label="lab_csx_EBPInvoluntaryRolloverLimit" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Involuntary Rollover Limit</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBPInvoluntaryRolloverLimit" xlink:href="csx-20260622.xsd#csx_EBPInvoluntaryRolloverLimit"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_csx_EBPInvoluntaryRolloverLimit" xlink:to="lab_csx_EBPInvoluntaryRolloverLimit" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAsset_019e1cf6-95dd-73f2-817f-043243ee4bb1_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAsset" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Total Assets</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAsset_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAsset" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Asset</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanAsset" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanAsset"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanAsset" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanAsset" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract_019e1cf6-953b-7a47-a6ab-8904f5ce8138_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">ASSETS</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Asset [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanAssetAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanAssetAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_RangeAxis_019e1cf6-95dd-7261-9b1c-82765ba4641f_terseLabel_en-US" xlink:label="lab_srt_RangeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Statistical Measurement [Axis]</link:label>
    <link:label id="lab_srt_RangeAxis_label_en-US" xlink:label="lab_srt_RangeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Statistical Measurement [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_RangeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_RangeAxis" xlink:to="lab_srt_RangeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract_019e1cf6-95dd-70a5-b270-d15405ffedca_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Additions</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable_019e1cf6-95dd-7c32-951c-794ff1160890_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Statement of Change in Net Asset Available for Benefit [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Statement of Change in Net Asset Available for Benefit [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustLineItems_019e1cf6-95dd-7406-8aa2-337dcd9d4c6b_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Master Trust [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Master Trust [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanMasterTrustLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanMasterTrustLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanMasterTrustLineItems" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanLiability_019e1cf6-95dd-74a1-8dfa-70e42b9d31be_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanLiability" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Total Liabilities</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanLiability_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanLiability" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Liability</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanLiability" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanLiability"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanLiability" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanLiability" xlink:type="arc" order="1"/>
    <link:label id="lab_csx_EBPESOPPercentInvestmentInCompanyCommonStock_019e1cf6-95dd-7ce0-b9ec-2f943fb4dea8_terseLabel_en-US" xlink:label="lab_csx_EBPESOPPercentInvestmentInCompanyCommonStock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">ESOP, percent investment in company common stock</link:label>
    <link:label id="lab_csx_EBPESOPPercentInvestmentInCompanyCommonStock_label_en-US" xlink:label="lab_csx_EBPESOPPercentInvestmentInCompanyCommonStock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, ESOP, Percent Investment In Company Common Stock</link:label>
    <link:label id="lab_csx_EBPESOPPercentInvestmentInCompanyCommonStock_documentation_en-US" xlink:label="lab_csx_EBPESOPPercentInvestmentInCompanyCommonStock" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, ESOP, Percent Investment In Company Common Stock</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBPESOPPercentInvestmentInCompanyCommonStock" xlink:href="csx-20260622.xsd#csx_EBPESOPPercentInvestmentInCompanyCommonStock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_csx_EBPESOPPercentInvestmentInCompanyCommonStock" xlink:to="lab_csx_EBPESOPPercentInvestmentInCompanyCommonStock" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_AmendmentFlag_019e1cf6-95dd-72c5-8ffb-48e68067d37c_terseLabel_en-US" xlink:label="lab_dei_AmendmentFlag" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Amendment Flag</link:label>
    <link:label id="lab_dei_AmendmentFlag_label_en-US" xlink:label="lab_dei_AmendmentFlag" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Amendment Flag</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_AmendmentFlag"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_AmendmentFlag" xlink:to="lab_dei_AmendmentFlag" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock_019e1cf6-95dd-7233-8f85-b1c6195ded88_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Basis of Presentation</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Basis of Accounting [Policy Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanBasisOfAccountingPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale_019e1cf6-95dd-752b-8740-a0f0da210539_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Due from brokers for securities sold</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment Sale, Receivable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableInvestmentSale" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable_019e1cf6-953b-75d7-9c55-e03787cb7d44_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairAndContractValue_019e1cf6-95dd-7e8e-89ab-728e3db725dc_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairAndContractValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investment in Master Trust (Note 3)</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairAndContractValue_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairAndContractValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Plan Interest in Master Trust, Fair and Contract Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairAndContractValue" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairAndContractValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairAndContractValue" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairAndContractValue" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Description of Plan and Accounting Change [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract_019e1cf6-95dd-7fee-abfb-ba23abbb1d13_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Receivables</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Receivable [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanReceivableAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock_019e1cf6-95dd-7bad-8fa7-cd66a35ad23b_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Schedule of Fair Value Hierarchy of Master Trust</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value and NAV [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_CommonStockMember_019e1cf6-95dd-76b0-816c-723d485192dc_terseLabel_en-US" xlink:label="lab_us-gaap_CommonStockMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Common stock</link:label>
    <link:label id="lab_us-gaap_CommonStockMember_label_en-US" xlink:label="lab_us-gaap_CommonStockMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Common Stock [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_CommonStockMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_CommonStockMember" xlink:to="lab_us-gaap_CommonStockMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentTypeCategorizationMember_019e1cf6-95dd-7f08-ba2f-764a6e6fbacc_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentTypeCategorizationMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investments [Domain]</link:label>
    <link:label id="lab_us-gaap_InvestmentTypeCategorizationMember_label_en-US" xlink:label="lab_us-gaap_InvestmentTypeCategorizationMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Investments [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeCategorizationMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InvestmentTypeCategorizationMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InvestmentTypeCategorizationMember" xlink:to="lab_us-gaap_InvestmentTypeCategorizationMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EbpNonemployerCommonStockMember_019e1cf6-95dd-79c6-818e-e4d55c883fa8_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EbpNonemployerCommonStockMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Other Common Stock</link:label>
    <link:label id="lab_us-gaap-ebp_EbpNonemployerCommonStockMember_label_en-US" xlink:label="lab_us-gaap-ebp_EbpNonemployerCommonStockMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Nonemployer, Common Stock [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EbpNonemployerCommonStockMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EbpNonemployerCommonStockMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EbpNonemployerCommonStockMember" xlink:to="lab_us-gaap-ebp_EbpNonemployerCommonStockMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Master Trust [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanMasterTrustAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanMasterTrustAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanMasterTrustAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock_019e1cf6-953b-7b55-a128-f9fb577d863c_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Use of Estimates</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Use of Estimate [Policy Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanUseOfEstimatePolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock_019e1cf6-953b-78a8-b73a-9ea078df3f3f_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_CoverAbstract_label_en-US" xlink:label="lab_dei_CoverAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Cover [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_CoverAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_CoverAbstract" xlink:to="lab_dei_CoverAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock_019e1cf6-95dd-7fa6-94db-628f2846a5c7_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Risks and Uncertainties</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Risk and Uncertainty [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanRiskAndUncertaintyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable_019e1cf6-95dd-7340-9267-70fbec32d8f6_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Accrued income</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment Income, Receivable</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentIncomeReceivable" xlink:type="arc" order="1"/>
    <link:label id="lab_srt_MinimumMember_019e1cf6-953b-7dce-9e2a-895125871dda_terseLabel_en-US" xlink:label="lab_srt_MinimumMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Minimum</link:label>
    <link:label id="lab_srt_MinimumMember_label_en-US" xlink:label="lab_srt_MinimumMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Minimum [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember" xlink:href="https://xbrl.fasb.org/srt/2026/elts/srt-2026.xsd#srt_MinimumMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_srt_MinimumMember" xlink:to="lab_srt_MinimumMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_InvestmentTypeAxis_019e1cf6-95dd-7a39-9b27-312df25a6819_terseLabel_en-US" xlink:label="lab_us-gaap_InvestmentTypeAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investment Type [Axis]</link:label>
    <link:label id="lab_us-gaap_InvestmentTypeAxis_label_en-US" xlink:label="lab_us-gaap_InvestmentTypeAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Investment Type [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentTypeAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_InvestmentTypeAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_InvestmentTypeAxis" xlink:to="lab_us-gaap_InvestmentTypeAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_csx_EBPReallocationsDisallowedReallocationPeriodFollowingTransaction_019e1cf6-95dd-7035-b264-f35e61bfd3f3_terseLabel_en-US" xlink:label="lab_csx_EBPReallocationsDisallowedReallocationPeriodFollowingTransaction" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Disallowed reallocation period following transaction</link:label>
    <link:label id="lab_csx_EBPReallocationsDisallowedReallocationPeriodFollowingTransaction_label_en-US" xlink:label="lab_csx_EBPReallocationsDisallowedReallocationPeriodFollowingTransaction" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Reallocations, Disallowed Reallocation Period Following Transaction</link:label>
    <link:label id="lab_csx_EBPReallocationsDisallowedReallocationPeriodFollowingTransaction_documentation_en-US" xlink:label="lab_csx_EBPReallocationsDisallowedReallocationPeriodFollowingTransaction" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Reallocations, Disallowed Reallocation Period Following Transaction</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBPReallocationsDisallowedReallocationPeriodFollowingTransaction" xlink:href="csx-20260622.xsd#csx_EBPReallocationsDisallowedReallocationPeriodFollowingTransaction"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_csx_EBPReallocationsDisallowedReallocationPeriodFollowingTransaction" xlink:to="lab_csx_EBPReallocationsDisallowedReallocationPeriodFollowingTransaction" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionNoncash_019e1cf6-953b-7937-8d3f-10ea4fde6b4f_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionNoncash" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Employer contribution, noncash</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionNoncash_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionNoncash" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Employer Contribution, Noncash</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionNoncash" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionNoncash"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionNoncash" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContributionNoncash" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant_019e1cf6-953b-78fa-ac1e-ab98b8afb15d_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Interest on notes receivable from members</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Interest Income on Note Receivable from Participant</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnNoteReceivableFromParticipant" xlink:type="arc" order="1"/>
    <link:label id="lab_csx_EBPParticipantLoanBasisSpreadOnVariableRate_019e1cf6-95dd-73b3-b613-c8232b4d9cff_terseLabel_en-US" xlink:label="lab_csx_EBPParticipantLoanBasisSpreadOnVariableRate" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Basis spread on variable rate</link:label>
    <link:label id="lab_csx_EBPParticipantLoanBasisSpreadOnVariableRate_label_en-US" xlink:label="lab_csx_EBPParticipantLoanBasisSpreadOnVariableRate" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Participant Loan, Basis Spread On Variable Rate</link:label>
    <link:label id="lab_csx_EBPParticipantLoanBasisSpreadOnVariableRate_documentation_en-US" xlink:label="lab_csx_EBPParticipantLoanBasisSpreadOnVariableRate" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Participant Loan, Basis Spread On Variable Rate</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBPParticipantLoanBasisSpreadOnVariableRate" xlink:href="csx-20260622.xsd#csx_EBPParticipantLoanBasisSpreadOnVariableRate"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionExcludingRollover_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionExcludingRollover" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Participant Contribution, Excluding Rollover</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionExcludingRollover" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForParticipantContributionExcludingRollover"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment_019e1cf6-95dd-7cdc-adf5-100c171e9109_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Net increase in the fair value of investments:</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase (Decrease) from Gain (Loss) on Investment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForGainLossOnInvestment"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestAndDividendIncomeOnInvestment_019e1cf6-95dd-7ce2-9480-5aad5283869a_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestAndDividendIncomeOnInvestment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Interest, dividend, and other income</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestAndDividendIncomeOnInvestment_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestAndDividendIncomeOnInvestment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Interest and Dividend Income on Investment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestAndDividendIncomeOnInvestment" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestAndDividendIncomeOnInvestment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestAndDividendIncomeOnInvestment" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestAndDividendIncomeOnInvestment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems_019e1cf6-95dd-799a-a78d-77abdaa1ef8c_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Description of Plan [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Description of Plan [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanPlanNumber_019e1cf6-953b-7aac-9d3f-a7074b3d9ab0_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanPlanNumber" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Plan number</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanPlanNumber_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanPlanNumber" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Plan Number</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanPlanNumber" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanPlanNumber"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanPlanNumber" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanPlanNumber" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems_019e1cf6-953b-776f-801b-7dd135d67dc9_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value and NAV [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value and NAV [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock_019e1cf6-95dd-7dcf-bf21-4074d5beea66_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Description of the Plan</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Description of Plan [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanDescriptionOfPlanTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems_019e1cf6-95dd-7414-a26c-42df2deeb900_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Statement of Change in Net Asset Available for Benefit [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Statement of Change in Net Asset Available for Benefit [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable_019e1cf6-95dd-779a-a359-a0d29121f68b_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Statement of Net Asset Available for Benefit [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Statement of Net Asset Available for Benefit [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitTable" xlink:type="arc" order="1"/>
    <link:label id="lab_csx_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm_019e1cf6-95dd-773e-979c-8a9907b79036_terseLabel_en-US" xlink:label="lab_csx_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Primary residence, borrowing term</link:label>
    <link:label id="lab_csx_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm_label_en-US" xlink:label="lab_csx_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable From Participant, Account, Primary Residence, Maximum Borrowing Term</link:label>
    <link:label id="lab_csx_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm_documentation_en-US" xlink:label="lab_csx_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable From Participant, Account, Primary Residence, Maximum Borrowing Term</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm" xlink:href="csx-20260622.xsd#csx_EBPNoteReceivableFromParticipantAccountPrimaryResidenceMaximumBorrowingTerm"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment_019e1cf6-95dd-75a0-adca-8a4b0aecef63_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Interest income on investment</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Interest Income on Investment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForInterestIncomeOnInvestment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems_019e1cf6-953b-7ab9-9d86-2c5fe4bd4463_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentLineItems"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustAndPlanInterestInMasterTrustDomain_019e1cf6-95dd-7a6b-a6a5-3c3a2e7b8b96_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustAndPlanInterestInMasterTrustDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Nonconsolidated, Master Trust and Plan Interest in Master Trust [Domain]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustAndPlanInterestInMasterTrustDomain_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustAndPlanInterestInMasterTrustDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Nonconsolidated, Master Trust and Plan Interest in Master Trust [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustAndPlanInterestInMasterTrustDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustAndPlanInterestInMasterTrustDomain"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember_019e1cf6-95dd-760e-b771-f7da18715db6_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">CSX Common Stock</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Employer, Common Stock [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerCommonStockMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Schedule of Asset Held for Investment [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanScheduleOfAssetHeldForInvestmentAbstract"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncrease"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense_019e1cf6-95dd-714d-a32c-6428ab6d8351_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Fees and expenses</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForAdministrativeExpense"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValue_019e1cf6-95dd-714b-8f55-bd643c49c9f0_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Stable Value Fund, at contract value:</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValue_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Contract Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValue" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentContractValue"/>
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    <link:label id="lab_csx_EBPPaymentOfBenefitsMonthlyInstallmentPeriod_019e1cf6-95dd-7606-8e6c-7944e8b47f06_terseLabel_en-US" xlink:label="lab_csx_EBPPaymentOfBenefitsMonthlyInstallmentPeriod" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Payment of benefits, monthly installment period</link:label>
    <link:label id="lab_csx_EBPPaymentOfBenefitsMonthlyInstallmentPeriod_label_en-US" xlink:label="lab_csx_EBPPaymentOfBenefitsMonthlyInstallmentPeriod" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Payment Of Benefits, Monthly Installment Period</link:label>
    <link:label id="lab_csx_EBPPaymentOfBenefitsMonthlyInstallmentPeriod_documentation_en-US" xlink:label="lab_csx_EBPPaymentOfBenefitsMonthlyInstallmentPeriod" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Payment Of Benefits, Monthly Installment Period</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBPPaymentOfBenefitsMonthlyInstallmentPeriod" xlink:href="csx-20260622.xsd#csx_EBPPaymentOfBenefitsMonthlyInstallmentPeriod"/>
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    <link:label id="lab_dei_DocumentInformationLineItems_019e1cf6-95dd-7e31-8e42-926ce4385832_terseLabel_en-US" xlink:label="lab_dei_DocumentInformationLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Document Information [Line Items]</link:label>
    <link:label id="lab_dei_DocumentInformationLineItems_label_en-US" xlink:label="lab_dei_DocumentInformationLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Document Information [Line Items]</link:label>
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    <link:label id="lab_us-gaap-ebp_EbpRiskAndUncertaintyLineItems_019e1cf6-95dd-7f6b-96d1-98df2548bb45_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EbpRiskAndUncertaintyLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Risk and Uncertainty [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EbpRiskAndUncertaintyLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EbpRiskAndUncertaintyLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Risk and Uncertainty [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EbpRiskAndUncertaintyLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EbpRiskAndUncertaintyLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EbpRiskAndUncertaintyLineItems" xlink:to="lab_us-gaap-ebp_EbpRiskAndUncertaintyLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EbpRiskAndUncertaintyTable_019e1cf6-95dd-7686-bc0e-65cbd3551d46_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EbpRiskAndUncertaintyTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Risk and Uncertainty [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EbpRiskAndUncertaintyTable_label_en-US" xlink:label="lab_us-gaap-ebp_EbpRiskAndUncertaintyTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Risk and Uncertainty [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EbpRiskAndUncertaintyTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EbpRiskAndUncertaintyTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EbpRiskAndUncertaintyTable" xlink:to="lab_us-gaap-ebp_EbpRiskAndUncertaintyTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTextBlock_019e1cf6-95dd-77de-a3b6-2313743910c4_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investment in Master Trust</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Master Trust [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanMasterTrustTextBlock"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Statement of Change in Net Asset Available for Benefit [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanStatementOfChangeInNetAssetAvailableForBenefitAbstract"/>
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    <link:label id="lab_us-gaap_FairValueInputsLevel2Member_019e1cf6-95dd-76dc-8139-5d7619720379_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel2Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Level 2</link:label>
    <link:label id="lab_us-gaap_FairValueInputsLevel2Member_label_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel2Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Fair Value, Inputs, Level 2 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueInputsLevel2Member"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractLineItems_019e1cf6-95dd-7251-a99e-cf8b59c6b80e_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Fully Benefit-Responsive Investment Contract [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Fully Benefit-Responsive Investment Contract [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanFullyBenefitResponsiveInvestmentContractLineItems"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution_019eb7c2-2c14-70c1-acb3-1d4cfea13d36_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Employer contributions</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Employer Contribution, Cash and Noncash</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForEmployerContribution"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTable_019e1cf6-95dd-76a1-89f2-093d34b0fb33_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Tax Status [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Tax Status [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanTaxStatusTable"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease_019e1cf6-95dd-77d9-b7d2-7f7a6599911a_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Net Increase</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase (Decrease)</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecrease"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Related Party and Party-in-Interest Transactions [Text Block]</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsAbstract"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerContributionReceivable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanEmployerContributionReceivable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution, Receivable</link:label>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract_019e1cf6-95dd-7fbd-a0cf-b9bb124d0a3f_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Investments</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment_019e1cf6-953b-761a-991e-34b6e10974d1_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Dividend income on investment</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase from Dividend Income on Investment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseForDividendIncomeOnInvestment" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant_019e1cf6-95dd-7943-8815-827af9aa0bcb_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Distributions to members</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Decrease from Payment to Participant</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseForPaymentToParticipant" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairValue_019e1cf6-953b-70d5-980a-3e234ec21f08_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairValue" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Total assets at fair value</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairValue_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairValue" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Plan Interest in Master Trust, Fair Value</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairValue" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairValue"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairValue" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentPlanInterestInMasterTrustFairValue" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_019e1cf6-953b-7068-9986-cbb3ccdc509e_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Fair Value Hierarchy and NAV [Domain]</link:label>
    <link:label id="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_label_en-US" xlink:label="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Fair Value Hierarchy and NAV [Domain]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:to="lab_us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_csx_EBPNoteReceivableFromParticipantPeriodPrecedingLoan_019e1cf6-95dd-743e-bad6-eb786fdbd2aa_terseLabel_en-US" xlink:label="lab_csx_EBPNoteReceivableFromParticipantPeriodPrecedingLoan" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Note receivable from participant, period preceding loan</link:label>
    <link:label id="lab_csx_EBPNoteReceivableFromParticipantPeriodPrecedingLoan_label_en-US" xlink:label="lab_csx_EBPNoteReceivableFromParticipantPeriodPrecedingLoan" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable From Participant, Period Preceding Loan</link:label>
    <link:label id="lab_csx_EBPNoteReceivableFromParticipantPeriodPrecedingLoan_documentation_en-US" xlink:label="lab_csx_EBPNoteReceivableFromParticipantPeriodPrecedingLoan" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable From Participant, Period Preceding Loan</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBPNoteReceivableFromParticipantPeriodPrecedingLoan" xlink:href="csx-20260622.xsd#csx_EBPNoteReceivableFromParticipantPeriodPrecedingLoan"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_csx_EBPNoteReceivableFromParticipantPeriodPrecedingLoan" xlink:to="lab_csx_EBPNoteReceivableFromParticipantPeriodPrecedingLoan" xlink:type="arc" order="1"/>
    <link:label id="lab_csx_EBP004Member_019e1cf6-95dd-7da2-801b-359128a5b724_terseLabel_en-US" xlink:label="lab_csx_EBP004Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP 004</link:label>
    <link:label id="lab_csx_EBP004Member_label_en-US" xlink:label="lab_csx_EBP004Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP 004 [Member]</link:label>
    <link:label id="lab_csx_EBP004Member_documentation_en-US" xlink:label="lab_csx_EBP004Member" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP 004</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBP004Member" xlink:href="csx-20260622.xsd#csx_EBP004Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_csx_EBP004Member" xlink:to="lab_csx_EBP004Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Statement of Net Asset Available for Benefit [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityInvestmentPurchase_019e1cf6-953b-70a4-938a-caf06aa075e3_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityInvestmentPurchase" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Due to brokers for securities purchased</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityInvestmentPurchase_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityInvestmentPurchase" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Liability for Investment Purchase</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanLiabilityInvestmentPurchase" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanLiabilityInvestmentPurchase"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanLiabilityInvestmentPurchase" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityInvestmentPurchase" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Tax Status [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanTaxStatusAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution_019e1cf6-95dd-7bc5-8995-76e2f78a33b6_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Current value</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Asset Held for Investment, Participant Loan, after Deemed Distribution</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanAssetHeldForInvestmentParticipantLoanAfterDeemedDistribution" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTable_019e1cf6-953b-7e56-a9b6-e88476182ed3_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Master Trust [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Master Trust [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanMasterTrustTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueInputsLevel12And3Member_019e1cf6-953b-7729-9786-c58cd1045024_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel12And3Member" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Total</link:label>
    <link:label id="lab_us-gaap_FairValueInputsLevel12And3Member_label_en-US" xlink:label="lab_us-gaap_FairValueInputsLevel12And3Member" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Fair Value, Inputs, Level 1, Level 2, and Level 3 [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel12And3Member" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueInputsLevel12And3Member"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueInputsLevel12And3Member" xlink:to="lab_us-gaap_FairValueInputsLevel12And3Member" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleLineItems_019e1cf6-953b-741c-a1ba-6e887b107ef9_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Accounting Standard Update and Change in Accounting Principle [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Accounting Standard Update and Change in Accounting Principle [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleLineItems" xlink:to="lab_us-gaap-ebp_EbpAccountingStandardUpdateAndChangeInAccountingPrincipleLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_DocumentType_019e1cf6-953b-70f8-84f5-bbc4d0b73c21_terseLabel_en-US" xlink:label="lab_dei_DocumentType" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Document Type</link:label>
    <link:label id="lab_dei_DocumentType_label_en-US" xlink:label="lab_dei_DocumentType" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Document Type</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentType"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_DocumentType" xlink:to="lab_dei_DocumentType" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityCentralIndexKey_019e1cf6-95dd-79a3-be29-1109a58a7688_terseLabel_en-US" xlink:label="lab_dei_EntityCentralIndexKey" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Entity Central Index Key</link:label>
    <link:label id="lab_dei_EntityCentralIndexKey_label_en-US" xlink:label="lab_dei_EntityCentralIndexKey" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity Central Index Key</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityCentralIndexKey"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityCentralIndexKey" xlink:to="lab_dei_EntityCentralIndexKey" xlink:type="arc" order="1"/>
    <link:label id="lab_csx_EBPInvoluntaryRolloverDistributionRequestPeriod_019e1cf6-95dd-75ec-b0bd-cf8263af21aa_terseLabel_en-US" xlink:label="lab_csx_EBPInvoluntaryRolloverDistributionRequestPeriod" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Distribution request period</link:label>
    <link:label id="lab_csx_EBPInvoluntaryRolloverDistributionRequestPeriod_label_en-US" xlink:label="lab_csx_EBPInvoluntaryRolloverDistributionRequestPeriod" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Involuntary Rollover, Distribution Request Period</link:label>
    <link:label id="lab_csx_EBPInvoluntaryRolloverDistributionRequestPeriod_documentation_en-US" xlink:label="lab_csx_EBPInvoluntaryRolloverDistributionRequestPeriod" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Involuntary Rollover, Distribution Request Period</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBPInvoluntaryRolloverDistributionRequestPeriod" xlink:href="csx-20260622.xsd#csx_EBPInvoluntaryRolloverDistributionRequestPeriod"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_csx_EBPInvoluntaryRolloverDistributionRequestPeriod" xlink:to="lab_csx_EBPInvoluntaryRolloverDistributionRequestPeriod" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate_019e1cf6-95dd-7489-a03f-68499aca2c6f_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Interest rate</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Asset Held for Investment, Participant Loan, Interest Rate</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanParticipantLoanInterestRate" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember_019e1cf6-95dd-7f54-ac47-d1051a43b34f_terseLabel_en-US" xlink:label="lab_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Common Collective Trusts</link:label>
    <link:label id="lab_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember_label_en-US" xlink:label="lab_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Common Collective Trust [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember" xlink:to="lab_us-gaap_DefinedBenefitPlanCommonCollectiveTrustMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EbpRiskAndUncertaintyAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EbpRiskAndUncertaintyAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Risk and Uncertainty [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EbpRiskAndUncertaintyAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EbpRiskAndUncertaintyAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EbpRiskAndUncertaintyAbstract" xlink:to="lab_us-gaap-ebp_EbpRiskAndUncertaintyAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems_019e1cf6-953b-7257-90a4-7f10544bfa16_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Tax Status [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Tax Status [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusLineItems" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract_019e1cf6-95dd-7186-a941-83473d246b6d_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Deductions</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Decrease [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitDecreaseAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant_019e1cf6-953b-7576-9d18-fa13c732cd49_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Notes receivable from members</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable from Participant</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipant" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustMember_019e1cf6-95dd-7c6a-b41c-6d7ecd65e3f2_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Nonconsolidated, Master Trust</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustMember_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Nonconsolidated, Master Trust [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustMember" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustMember" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis_019e1cf6-953b-74a1-a97b-25fd7a331084_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Fair Value Hierarchy and NAV [Axis]</link:label>
    <link:label id="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis_label_en-US" xlink:label="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Fair Value Hierarchy and NAV [Axis]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:to="lab_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock_019e1cf6-95dd-7817-b54b-e639730d5bab_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Summary of Significant Accounting Policies</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Summary of Accounting Policy [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanSummaryOfAccountingPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityRegistrantName_019e1cf6-95dd-7f31-ad4a-65651487740c_terseLabel_en-US" xlink:label="lab_dei_EntityRegistrantName" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Entity Registrant Name</link:label>
    <link:label id="lab_dei_EntityRegistrantName_label_en-US" xlink:label="lab_dei_EntityRegistrantName" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity Registrant Name</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_EntityRegistrantName"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityRegistrantName" xlink:to="lab_dei_EntityRegistrantName" xlink:type="arc" order="1"/>
    <link:label id="lab_csx_EBPParticipantContributionMaximumContributionToEligibleCompensationPercentage_019e1cf6-95dd-7495-a0b1-90c99e428bb2_terseLabel_en-US" xlink:label="lab_csx_EBPParticipantContributionMaximumContributionToEligibleCompensationPercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Participant contribution, maximum annual compensation to total compensation, percentage</link:label>
    <link:label id="lab_csx_EBPParticipantContributionMaximumContributionToEligibleCompensationPercentage_label_en-US" xlink:label="lab_csx_EBPParticipantContributionMaximumContributionToEligibleCompensationPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Participant Contribution, Maximum Contribution to Eligible Compensation, Percentage</link:label>
    <link:label id="lab_csx_EBPParticipantContributionMaximumContributionToEligibleCompensationPercentage_documentation_en-US" xlink:label="lab_csx_EBPParticipantContributionMaximumContributionToEligibleCompensationPercentage" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Participant Contribution, Maximum Contribution to Eligible Compensation, Percentage</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBPParticipantContributionMaximumContributionToEligibleCompensationPercentage" xlink:href="csx-20260622.xsd#csx_EBPParticipantContributionMaximumContributionToEligibleCompensationPercentage"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_csx_EBPParticipantContributionMaximumContributionToEligibleCompensationPercentage" xlink:to="lab_csx_EBPParticipantContributionMaximumContributionToEligibleCompensationPercentage" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTableTextBlock_019e1cf6-95dd-73f1-8a60-3eedf6cabad2_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Schedule of Financial Information of Master Trust</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTableTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTableTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Master Trust [Table Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTableTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanMasterTrustTableTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTableTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanMasterTrustTableTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract_019e1cf6-95dd-7af3-bc46-86acabc0fa10_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">LIABILITIES</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Liability [Abstract]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanLiabilityAbstract" xlink:type="arc" order="1"/>
    <link:label id="lab_csx_EBPEmployerContributionVestingPercentage_019e1cf6-95dd-7f86-b0a5-042ed22793ba_terseLabel_en-US" xlink:label="lab_csx_EBPEmployerContributionVestingPercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Vested (in percentage)</link:label>
    <link:label id="lab_csx_EBPEmployerContributionVestingPercentage_label_en-US" xlink:label="lab_csx_EBPEmployerContributionVestingPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution Vesting Percentage</link:label>
    <link:label id="lab_csx_EBPEmployerContributionVestingPercentage_documentation_en-US" xlink:label="lab_csx_EBPEmployerContributionVestingPercentage" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Employer Contribution Vesting Percentage</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBPEmployerContributionVestingPercentage" xlink:href="csx-20260622.xsd#csx_EBPEmployerContributionVestingPercentage"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_csx_EBPEmployerContributionVestingPercentage" xlink:to="lab_csx_EBPEmployerContributionVestingPercentage" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock_019e1cf6-95dd-7de2-9573-67456a7eebe4_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Income Tax Status</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Tax Status [Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanTaxStatusTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage_019e1cf6-95dd-7721-8418-f4675e373598_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Account balance (in percentage)</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable from Participant, Account, Maximum Borrowing, to Total Account, Percentage</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantAccountMaximumBorrowingToTotalAccountPercentage" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_DocumentInformationTable_019e1cf6-95dd-7ddd-849b-6c388b01dc34_terseLabel_en-US" xlink:label="lab_dei_DocumentInformationTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Document Information [Table]</link:label>
    <link:label id="lab_dei_DocumentInformationTable_label_en-US" xlink:label="lab_dei_DocumentInformationTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Document Information [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentInformationTable" xlink:href="https://xbrl.sec.gov/dei/2026/dei-2026.xsd#dei_DocumentInformationTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_DocumentInformationTable" xlink:to="lab_dei_DocumentInformationTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock_019e1cf6-953b-76f2-b82e-6897f4250422_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Notes Receivable from Members</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Note Receivable from Participant [Policy Text Block]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanNoteReceivableFromParticipantPolicyTextBlock" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment_019e1cf6-95dd-70ff-9768-65602bed3f84_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Net gain from investment in Master Trust (Note 3)</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment_019e1cf6-95dd-7755-a4e0-56306de58cfe_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Total investment gain for the Master Trust</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Increase (Decrease) from Income (Loss) on Investment</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanChangeInNetAssetAvailableForBenefitIncreaseDecreaseForIncomeLossOnInvestment"/>
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    <link:label id="lab_csx_EBPChangeInNetAssetAvailableForBenefitTransferToPlan_019e1cf6-95dd-7e7a-8cf1-5e834a38d195_terseLabel_en-US" xlink:label="lab_csx_EBPChangeInNetAssetAvailableForBenefitTransferToPlan" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Transfers to Plan</link:label>
    <link:label id="lab_csx_EBPChangeInNetAssetAvailableForBenefitTransferToPlan_label_en-US" xlink:label="lab_csx_EBPChangeInNetAssetAvailableForBenefitTransferToPlan" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Transfer to Plan</link:label>
    <link:label id="lab_csx_EBPChangeInNetAssetAvailableForBenefitTransferToPlan_documentation_en-US" xlink:label="lab_csx_EBPChangeInNetAssetAvailableForBenefitTransferToPlan" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Transfer to Plan</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBPChangeInNetAssetAvailableForBenefitTransferToPlan" xlink:href="csx-20260622.xsd#csx_EBPChangeInNetAssetAvailableForBenefitTransferToPlan"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_csx_EBPChangeInNetAssetAvailableForBenefitTransferToPlan" xlink:to="lab_csx_EBPChangeInNetAssetAvailableForBenefitTransferToPlan" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustAndPlanInterestInMasterTrustAxis_019e1cf6-95dd-791c-ae1c-11e0efd6ea16_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustAndPlanInterestInMasterTrustAxis" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Nonconsolidated, Master Trust and Plan Interest in Master Trust [Axis]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustAndPlanInterestInMasterTrustAxis_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNonconsolidatedMasterTrustAndPlanInterestInMasterTrustAxis" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Nonconsolidated, Master Trust and Plan Interest in Master Trust [Axis]</link:label>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsLineItems_019e1cf6-95dd-75a2-980a-470ba888ad49_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Related Party and Party-in-Interest Transactions [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Related Party and Party-in-Interest Transactions [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanRelatedPartyAndPartyInInterestTransactionsLineItems"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit_019e1cf6-953b-7607-a300-a292b4338536_totalLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Net Assets Available for Benefits at End of Year</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit_019e1cf6-953b-73f5-aa03-d2899ee655cf_periodStartLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:type="resource" xml:lang="en-US">Net Assets Available for Benefits at Beginning of Year</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit_019e1cf6-953b-730c-a20b-1d8d0333a24e_periodEndLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:type="resource" xml:lang="en-US">Net Assets Available for Benefits at End of Year</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Net Asset Available for Benefit</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanNetAssetAvailableForBenefit" xlink:type="arc" order="1"/>
    <link:label id="lab_dei_EntityDomain_019e1cf6-95dd-71aa-95e8-5ef1d914d12a_terseLabel_en-US" xlink:label="lab_dei_EntityDomain" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Entity [Domain]</link:label>
    <link:label id="lab_dei_EntityDomain_label_en-US" xlink:label="lab_dei_EntityDomain" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Entity [Domain]</link:label>
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    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_dei_EntityDomain" xlink:to="lab_dei_EntityDomain" xlink:type="arc" order="1"/>
    <link:label id="lab_csx_EBPFullyBenefitResponsiveInvestmentContractMinimumCreditingRate_019e1cf6-95dd-7db1-9592-f62516c5fe84_terseLabel_en-US" xlink:label="lab_csx_EBPFullyBenefitResponsiveInvestmentContractMinimumCreditingRate" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Minimum crediting rate</link:label>
    <link:label id="lab_csx_EBPFullyBenefitResponsiveInvestmentContractMinimumCreditingRate_label_en-US" xlink:label="lab_csx_EBPFullyBenefitResponsiveInvestmentContractMinimumCreditingRate" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Fully Benefit-Responsive Investment Contract, Minimum Crediting Rate</link:label>
    <link:label id="lab_csx_EBPFullyBenefitResponsiveInvestmentContractMinimumCreditingRate_documentation_en-US" xlink:label="lab_csx_EBPFullyBenefitResponsiveInvestmentContractMinimumCreditingRate" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Fully Benefit-Responsive Investment Contract, Minimum Crediting Rate</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBPFullyBenefitResponsiveInvestmentContractMinimumCreditingRate" xlink:href="csx-20260622.xsd#csx_EBPFullyBenefitResponsiveInvestmentContractMinimumCreditingRate"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_csx_EBPFullyBenefitResponsiveInvestmentContractMinimumCreditingRate" xlink:to="lab_csx_EBPFullyBenefitResponsiveInvestmentContractMinimumCreditingRate" xlink:type="arc" order="1"/>
    <link:label id="lab_csx_EBPParticipantContributionMaximumAnnualCompensationToTotalCompensationIncrementPercentage_019e1cf6-95dd-7770-8f26-8b7acb2bacb3_terseLabel_en-US" xlink:label="lab_csx_EBPParticipantContributionMaximumAnnualCompensationToTotalCompensationIncrementPercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Participant contribution, pretax, maximum annual compensation to total compensation, increment, percentage</link:label>
    <link:label id="lab_csx_EBPParticipantContributionMaximumAnnualCompensationToTotalCompensationIncrementPercentage_label_en-US" xlink:label="lab_csx_EBPParticipantContributionMaximumAnnualCompensationToTotalCompensationIncrementPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Participant Contribution, Maximum Annual Compensation to Total Compensation, Increment, Percentage</link:label>
    <link:label id="lab_csx_EBPParticipantContributionMaximumAnnualCompensationToTotalCompensationIncrementPercentage_documentation_en-US" xlink:label="lab_csx_EBPParticipantContributionMaximumAnnualCompensationToTotalCompensationIncrementPercentage" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Participant Contribution, Maximum Annual Compensation to Total Compensation, Increment, Percentage</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_csx_EBPParticipantContributionMaximumAnnualCompensationToTotalCompensationIncrementPercentage" xlink:href="csx-20260622.xsd#csx_EBPParticipantContributionMaximumAnnualCompensationToTotalCompensationIncrementPercentage"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_csx_EBPParticipantContributionMaximumAnnualCompensationToTotalCompensationIncrementPercentage" xlink:to="lab_csx_EBPParticipantContributionMaximumAnnualCompensationToTotalCompensationIncrementPercentage" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember_019e1cf6-953b-7af4-9220-fafa7afd6079_terseLabel_en-US" xlink:label="lab_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">NAV</link:label>
    <link:label id="lab_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember_label_en-US" xlink:label="lab_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Fair Value Measured at Net Asset Value Per Share [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember" xlink:href="https://xbrl.fasb.org/us-gaap/2026/elts/us-gaap-2026.xsd#us-gaap_FairValueMeasuredAtNetAssetValuePerShareMember"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTable_019e1cf6-953b-7ef4-972b-cc5db8e42818_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTable" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value and NAV [Table]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTable_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTable" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Investment, Fair Value and NAV [Table]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTable" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTable"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTable" xlink:to="lab_us-gaap-ebp_EmployeeBenefitPlanInvestmentFairValueAndNavTable" xlink:type="arc" order="1"/>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInterestInMasterTrustPercentage_019e1cf6-953b-71f4-a2bf-26372795ea06_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInterestInMasterTrustPercentage" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Plan&#8217;s Percentage of Investment in the Master Trust&#8217;s Net Assets</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanInterestInMasterTrustPercentage_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanInterestInMasterTrustPercentage" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Interest in Master Trust, Percentage</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanInterestInMasterTrustPercentage" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanInterestInMasterTrustPercentage"/>
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    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitLineItems_019e1cf6-953b-7ff7-b462-aea6451869cb_terseLabel_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitLineItems" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">EBP, Statement of Net Asset Available for Benefit [Line Items]</link:label>
    <link:label id="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitLineItems_label_en-US" xlink:label="lab_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitLineItems" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">EBP, Statement of Net Asset Available for Benefit [Line Items]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitLineItems" xlink:href="https://xbrl.fasb.org/us-gaap/2026/ebp/elts/us-gaap-ebp-2026.xsd#us-gaap-ebp_EmployeeBenefitPlanStatementOfNetAssetAvailableForBenefitLineItems"/>
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    <link:label id="lab_csx_EBPChangeInNetAssetAvailableForBenefitTransferFromPlan_019e1cf6-95dd-73f7-9cf0-12530b63f6cb_terseLabel_en-US" xlink:label="lab_csx_EBPChangeInNetAssetAvailableForBenefitTransferFromPlan" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Transfers from the Plan</link:label>
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    <link:label id="lab_csx_EBPChangeInNetAssetAvailableForBenefitTransferFromPlan_documentation_en-US" xlink:label="lab_csx_EBPChangeInNetAssetAvailableForBenefitTransferFromPlan" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">EBP, Change in Net Asset Available for Benefit, Transfer From Plan</link:label>
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